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Ulugbek S. Kamilov

Publications and source records attributed to Ulugbek S. Kamilov.

At least 73 records · Page 4Linked to original sources

Plug-and-Play Methods for Integrating Physical and Learned Models in Computational Imaging

Plug-and-Play Priors (PnP) is one of the most widely-used frameworks for solving computational imaging problems through the integration of physical models and learned models. PnP leverages high-fidelity physical sensor models and powerful machine learning methods for prior modeling of data to provide state-of-the-art reconstruction algorithms. PnP algorithms alternate between minimizing a data-fidelity term to promote data consistency and imposing a learned regularizer in the form of an image denoiser. Recent highly-successful applications of PnP algorithms include bio-microscopy, computerized tomography, magnetic resonance imaging, and joint ptycho-tomography. This article presents a unified and principled review of PnP by tracing its roots, describing its major variations, summarizing main results, and discussing applications in computational imaging. We also point the way towards further developments by discussing recent results on equilibrium equations that formulate the problem associated with PnP algorithms.

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Deep Model-Based Architectures for Inverse Problems under Mismatched Priors

There is a growing interest in deep model-based architectures (DMBAs) for solving imaging inverse problems by combining physical measurement models and learned image priors specified using convolutional neural nets (CNNs). For example, well-known frameworks for systematically designing DMBAs include plug-and-play priors (PnP), deep unfolding (DU), and deep equilibrium models (DEQ). While the empirical performance and theoretical properties of DMBAs have been widely investigated, the existing work in the area has primarily focused on their performance when the desired image prior is known exactly. This work addresses the gap in the prior work by providing new theoretical and numerical insights into DMBAs under mismatched CNN priors. Mismatched priors arise naturally when there is a distribution shift between training and testing data, for example, due to test images being from a different distribution than images used for training the CNN prior. They also arise when the CNN prior used for inference is an approximation of some desired statistical estimator (MAP or MMSE). Our theoretical analysis provides explicit error bounds on the solution due to the mismatched CNN priors under a set of clearly specified assumptions. Our numerical results compare the empirical performance of DMBAs under realistic distribution shifts and approximate statistical estimators.

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Online Deep Equilibrium Learning for Regularization by Denoising

Plug-and-Play Priors (PnP) and Regularization by Denoising (RED) are widely-used frameworks for solving imaging inverse problems by computing fixed-points of operators combining physical measurement models and learned image priors. While traditional PnP/RED formulations have focused on priors specified using image denoisers, there is a growing interest in learning PnP/RED priors that are end-to-end optimal. The recent Deep Equilibrium Models (DEQ) framework has enabled memory-efficient end-to-end learning of PnP/RED priors by implicitly differentiating through the fixed-point equations without storing intermediate activation values. However, the dependence of the computational/memory complexity of the measurement models in PnP/RED on the total number of measurements leaves DEQ impractical for many imaging applications. We propose ODER as a new strategy for improving the efficiency of DEQ through stochastic approximations of the measurement models. We theoretically analyze ODER giving insights into its convergence and ability to approximate the traditional DEQ approach. Our numerical results suggest the potential improvements in training/testing complexity due to ODER on three distinct imaging applications.

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Image Reconstruction for MRI using Deep CNN Priors Trained without Groundtruth

We propose a new plug-and-play priors (PnP) based MR image reconstruction method that systematically enforces data consistency while also exploiting deep-learning priors. Our prior is specified through a convolutional neural network (CNN) trained without any artifact-free ground truth to remove undersampling artifacts from MR images. The results on reconstructing free-breathing MRI data into ten respiratory phases show that the method can form high-quality 4D images from severely undersampled measurements corresponding to acquisitions of about 1 and 2 minutes in length. The results also highlight the competitive performance of the method compared to several popular alternatives, including the TGV regularization and traditional UNet3D.

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Learning Cross-Video Neural Representations for High-Quality Frame Interpolation

This paper considers the problem of temporal video interpolation, where the goal is to synthesize a new video frame given its two neighbors. We propose Cross-Video Neural Representation (CURE) as the first video interpolation method based on neural fields (NF). NF refers to the recent class of methods for the neural representation of complex 3D scenes that has seen widespread success and application across computer vision. CURE represents the video as a continuous function parameterized by a coordinate-based neural network, whose inputs are the spatiotemporal coordinates and outputs are the corresponding RGB values. CURE introduces a new architecture that conditions the neural network on the input frames for imposing space-time consistency in the synthesized video. This not only improves the final interpolation quality, but also enables CURE to learn a prior across multiple videos. Experimental evaluations show that CURE achieves the state-of-the-art performance on video interpolation on several benchmark datasets.

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Monotonically Convergent Regularization by Denoising

Regularization by denoising (RED) is a widely-used framework for solving inverse problems by leveraging image denoisers as image priors. Recent work has reported the state-of-the-art performance of RED in a number of imaging applications using pre-trained deep neural nets as denoisers. Despite the recent progress, the stable convergence of RED algorithms remains an open problem. The existing RED theory only guarantees stability for convex data-fidelity terms and nonexpansive denoisers. This work addresses this issue by developing a new monotone RED (MRED) algorithm, whose convergence does not require nonexpansiveness of the deep denoising prior. Simulations on image deblurring and compressive sensing recovery from random matrices show the stability of MRED even when the traditional RED algorithm diverges.

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Bregman Plug-and-Play Priors

The past few years have seen a surge of activity around integration of deep learning networks and optimization algorithms for solving inverse problems. Recent work on plug-and-play priors (PnP), regularization by denoising (RED), and deep unfolding has shown the state-of-the-art performance of such integration in a variety of applications. However, the current paradigm for designing such algorithms is inherently Euclidean, due to the usage of the quadratic norm within the projection and proximal operators. We propose to broaden this perspective by considering a non-Euclidean setting based on the more general Bregman distance. Our new Bregman Proximal Gradient Method variant of PnP (PnP-BPGM) and Bregman Steepest Descent variant of RED (RED-BSD) replace the traditional updates in PnP and RED from the quadratic norms to more general Bregman distance. We present a theoretical convergence result for PnP-BPGM and demonstrate the effectiveness of our algorithms on Poisson linear inverse problems.

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Learning-based Motion Artifact Removal Networks (LEARN) for Quantitative $R_2^\ast$ Mapping

Purpose: To introduce two novel learning-based motion artifact removal networks (LEARN) for the estimation of quantitative motion- and $B0$-inhomogeneity-corrected $R_2^\ast$ maps from motion-corrupted multi-Gradient-Recalled Echo (mGRE) MRI data. Methods: We train two convolutional neural networks (CNNs) to correct motion artifacts for high-quality estimation of quantitative $B0$-inhomogeneity-corrected $R_2^\ast$ maps from mGRE sequences. The first CNN, LEARN-IMG, performs motion correction on complex mGRE images, to enable the subsequent computation of high-quality motion-free quantitative $R_2^\ast$ (and any other mGRE-enabled) maps using the standard voxel-wise analysis or machine-learning-based analysis. The second CNN, LEARN-BIO, is trained to directly generate motion- and $B0$-inhomogeneity-corrected quantitative $R_2^\ast$ maps from motion-corrupted magnitude-only mGRE images by taking advantage of the biophysical model describing the mGRE signal decay. We show that both CNNs trained on synthetic MR images are capable of suppressing motion artifacts while preserving details in the predicted quantitative $R_2^\ast$ maps. Significant reduction of motion artifacts on experimental in vivo motion-corrupted data has also been achieved by using our trained models. Conclusion: Both LEARN-IMG and LEARN-BIO can enable the computation of high-quality motion- and $B0$-inhomogeneity-corrected $R_2^\ast$ maps. LEARN-IMG performs motion correction on mGRE images and relies on the subsequent analysis for the estimation of $R_2^\ast$ maps, while LEARN-BIO directly performs motion- and $B0$-inhomogeneity-corrected $R_2^\ast$ estimation. Both LEARN-IMG and LEARN-BIO jointly process all the available gradient echoes, which enables them to exploit spatial patterns available in the data. The high computational speed of LEARN-BIO is an advantage that can lead to a broader clinical application.

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Deformation-Compensated Learning for Image Reconstruction without Ground Truth

Deep neural networks for medical image reconstruction are traditionally trained using high-quality ground-truth images as training targets. Recent work on Noise2Noise (N2N) has shown the potential of using multiple noisy measurements of the same object as an alternative to having a ground-truth. However, existing N2N-based methods are not suitable for learning from the measurements of an object undergoing nonrigid deformation. This paper addresses this issue by proposing the deformation-compensated learning (DeCoLearn) method for training deep reconstruction networks by compensating for object deformations. A key component of DeCoLearn is a deep registration module, which is jointly trained with the deep reconstruction network without any ground-truth supervision. We validate DeCoLearn on both simulated and experimentally collected magnetic resonance imaging (MRI) data and show that it significantly improves imaging quality.

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Recovery Analysis for Plug-and-Play Priors using the Restricted Eigenvalue Condition

The plug-and-play priors (PnP) and regularization by denoising (RED) methods have become widely used for solving inverse problems by leveraging pre-trained deep denoisers as image priors. While the empirical imaging performance and the theoretical convergence properties of these algorithms have been widely investigated, their recovery properties have not previously been theoretically analyzed. We address this gap by showing how to establish theoretical recovery guarantees for PnP/RED by assuming that the solution of these methods lies near the fixed-points of a deep neural network. We also present numerical results comparing the recovery performance of PnP/RED in compressive sensing against that of recent compressive sensing algorithms based on generative models. Our numerical results suggest that PnP with a pre-trained artifact removal network provides significantly better results compared to the existing state-of-the-art methods.

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CoIL: Coordinate-based Internal Learning for Imaging Inverse Problems

We propose Coordinate-based Internal Learning (CoIL) as a new deep-learning (DL) methodology for the continuous representation of measurements. Unlike traditional DL methods that learn a mapping from the measurements to the desired image, CoIL trains a multilayer perceptron (MLP) to encode the complete measurement field by mapping the coordinates of the measurements to their responses. CoIL is a self-supervised method that requires no training examples besides the measurements of the test object itself. Once the MLP is trained, CoIL generates new measurements that can be used within a majority of image reconstruction methods. We validate CoIL on sparse-view computed tomography using several widely-used reconstruction methods, including purely model-based methods and those based on DL. Our results demonstrate the ability of CoIL to consistently improve the performance of all the considered methods by providing high-fidelity measurement fields.

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Scalable Plug-and-Play ADMM with Convergence Guarantees

Plug-and-play priors (PnP) is a broadly applicable methodology for solving inverse problems by exploiting statistical priors specified as denoisers. Recent work has reported the state-of-the-art performance of PnP algorithms using pre-trained deep neural nets as denoisers in a number of imaging applications. However, current PnP algorithms are impractical in large-scale settings due to their heavy computational and memory requirements. This work addresses this issue by proposing an incremental variant of the widely used PnP-ADMM algorithm, making it scalable to large-scale datasets. We theoretically analyze the convergence of the algorithm under a set of explicit assumptions, extending recent theoretical results in the area. Additionally, we show the effectiveness of our algorithm with nonsmooth data-fidelity terms and deep neural net priors, its fast convergence compared to existing PnP algorithms, and its scalability in terms of speed and memory.

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SGD-Net: Efficient Model-Based Deep Learning with Theoretical Guarantees

Deep unfolding networks have recently gained popularity in the context of solving imaging inverse problems. However, the computational and memory complexity of data-consistency layers within traditional deep unfolding networks scales with the number of measurements, limiting their applicability to large-scale imaging inverse problems. We propose SGD-Net as a new methodology for improving the efficiency of deep unfolding through stochastic approximations of the data-consistency layers. Our theoretical analysis shows that SGD-Net can be trained to approximate batch deep unfolding networks to an arbitrary precision. Our numerical results on intensity diffraction tomography and sparse-view computed tomography show that SGD-Net can match the performance of the batch network at a fraction of training and testing complexity.

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Joint Reconstruction and Calibration using Regularization by Denoising

Regularization by denoising (RED) is a broadly applicable framework for solving inverse problems by using priors specified as denoisers. While RED has been shown to provide state-of-the-art performance in a number of applications, existing RED algorithms require exact knowledge of the measurement operator characterizing the imaging system, limiting their applicability in problems where the measurement operator has parametric uncertainties. We propose a new method, called Calibrated RED (Cal-RED), that enables joint calibration of the measurement operator along with reconstruction of the unknown image. Cal-RED extends the traditional RED methodology to imaging problems that require the calibration of the measurement operator. We validate Cal-RED on the problem of image reconstruction in computerized tomography (CT) under perturbed projection angles. Our results corroborate the effectiveness of Cal-RED for joint calibration and reconstruction using pre-trained deep denoisers as image priors.

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Async-RED: A Provably Convergent Asynchronous Block Parallel Stochastic Method using Deep Denoising Priors

Regularization by denoising (RED) is a recently developed framework for solving inverse problems by integrating advanced denoisers as image priors. Recent work has shown its state-of-the-art performance when combined with pre-trained deep denoisers. However, current RED algorithms are inadequate for parallel processing on multicore systems. We address this issue by proposing a new asynchronous RED (ASYNC-RED) algorithm that enables asynchronous parallel processing of data, making it significantly faster than its serial counterparts for large-scale inverse problems. The computational complexity of ASYNC-RED is further reduced by using a random subset of measurements at every iteration. We present complete theoretical analysis of the algorithm by establishing its convergence under explicit assumptions on the data-fidelity and the denoiser. We validate ASYNC-RED on image recovery using pre-trained deep denoisers as priors.

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Deep Image Reconstruction using Unregistered Measurements without Groundtruth

One of the key limitations in conventional deep learning based image reconstruction is the need for registered pairs of training images containing a set of high-quality groundtruth images. This paper addresses this limitation by proposing a novel unsupervised deep registration-augmented reconstruction method (U-Dream) for training deep neural nets to reconstruct high-quality images by directly mapping pairs of unregistered and artifact-corrupted images. The ability of U-Dream to circumvent the need for accurately registered data makes it widely applicable to many biomedical image reconstruction tasks. We validate it in accelerated magnetic resonance imaging (MRI) by training an image reconstruction model directly on pairs of undersampled measurements from images that have undergone nonrigid deformations.

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SIMBA: Scalable Inversion in Optical Tomography using Deep Denoising Priors

Two features desired in a three-dimensional (3D) optical tomographic image reconstruction algorithm are the ability to reduce imaging artifacts and to do fast processing of large data volumes. Traditional iterative inversion algorithms are impractical in this context due to their heavy computational and memory requirements. We propose and experimentally validate a novel scalable iterative mini-batch algorithm (SIMBA) for fast and high-quality optical tomographic imaging. SIMBA enables high-quality imaging by combining two complementary information sources: the physics of the imaging system characterized by its forward model and the imaging prior characterized by a denoising deep neural net. SIMBA easily scales to very large 3D tomographic datasets by processing only a small subset of measurements at each iteration. We establish the theoretical fixed-point convergence of SIMBA under nonexpansive denoisers for convex data-fidelity terms. We validate SIMBA on both simulated and experimentally collected intensity diffraction tomography (IDT) datasets. Our results show that SIMBA can significantly reduce the computational burden of 3D image formation without sacrificing the imaging quality.

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RARE: Image Reconstruction using Deep Priors Learned without Ground Truth

Regularization by denoising (RED) is an image reconstruction framework that uses an image denoiser as a prior. Recent work has shown the state-of-the-art performance of RED with learned denoisers corresponding to pre-trained convolutional neural nets (CNNs). In this work, we propose to broaden the current denoiser-centric view of RED by considering priors corresponding to networks trained for more general artifact-removal. The key benefit of the proposed family of algorithms, called regularization by artifact-removal (RARE), is that it can leverage priors learned on datasets containing only undersampled measurements. This makes RARE applicable to problems where it is practically impossible to have fully-sampled groundtruth data for training. We validate RARE on both simulated and experimentally collected data by reconstructing a free-breathing whole-body 3D MRIs into ten respiratory phases from heavily undersampled k-space measurements. Our results corroborate the potential of learning regularizers for iterative inversion directly on undersampled and noisy measurements.

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