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Utz-Uwe Haus

Publications and source records attributed to Utz-Uwe Haus.

20 records · Page 2Linked to original sources

Computing knock out strategies in metabolic networks

Given a metabolic network in terms of its metabolites and reactions, our goal is to efficiently compute the minimal knock out sets of reactions required to block a given behaviour. We describe an algorithm which improves the computation of these knock out sets when the elementary modes (minimal functional subsystems) of the network are given. We also describe an algorithm which computes both the knock out sets and the elementary modes containing the blocked reactions directly from the description of the network and whose worst-case computational complexity is better than the algorithms currently in use for these problems. Computational results are included.

q-bio.QM↗

On crepant resolutions of 2-parameter series of Gorenstein cyclic quotient singularities

An immediate generalization of the classical McKay correspondence for Gorenstein quotient spaces $\Bbb{C}^{r}/G$ in dimensions $r\geq 4$ would primarily demand the existence of projective, crepant, full desingularizations. Since this is not always possible, it is natural to ask about special classes of such quotient spaces which would satisfy the above property. In this paper we give explicit necessary and sufficient conditions under which 2-parameter series of Gorenstein cyclic quotient singularities have torus-equivariant resolutions of this specific sort in all dimensions.

math.AG↗