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Uwe Aickelin

Publications and source records attributed to Uwe Aickelin.

At least 37 records · Page 2Linked to original sources

On the Importance of Diversity in Re-Sampling for Imbalanced Data and Rare Events in Mortality Risk Models

Surgical risk increases significantly when patients present with comorbid conditions. This has resulted in the creation of numerous risk stratification tools with the objective of formulating associated surgical risk to assist both surgeons and patients in decision-making. The Surgical Outcome Risk Tool (SORT) is one of the tools developed to predict mortality risk throughout the entire perioperative period for major elective in-patient surgeries in the UK. In this study, we enhance the original SORT prediction model (UK SORT) by addressing the class imbalance within the dataset. Our proposed method investigates the application of diversity-based selection on top of common re-sampling techniques to enhance the classifier's capability in detecting minority (mortality) events. Diversity amongst training datasets is an essential factor in ensuring re-sampled data keeps an accurate depiction of the minority/majority class region, thereby solving the generalization problem of mainstream sampling approaches. We incorporate the use of the Solow-Polasky measure as a drop-in functionality to evaluate diversity, with the addition of greedy algorithms to identify and discard subsets that share the most similarity. Additionally, through empirical experiments, we prove that the performance of the classifier trained over diversity-based dataset outperforms the original classifier over ten external datasets. Our diversity-based re-sampling method elevates the performance of the UK SORT algorithm by 1.4$.

cs.LG↗

A new interval-based aggregation approach based on bagging and Interval Agreement Approach (IAA) in ensemble learning

The main aim in ensemble learning is using multiple individual classifiers outputs rather than one classifier output to aggregate them for more accurate classification. Generating an ensemble classifier generally is composed of three steps: selecting the base classifier, applying a sampling strategy to generate different individual classifiers and aggregation the classifiers outputs. This paper focuses on the classifiers outputs aggregation step and presents a new interval-based aggregation modeling using bagging resampling approach and Interval Agreement Approach (IAA) in ensemble learning. IAA is an interesting and practical aggregation approach in decision making which was introduced to combine decision makers opinions when they present their opinions by intervals. In this paper, in addition to implementing a new aggregation approach in ensemble learning, we designed some experiments to encourage researchers to use interval modeling in ensemble learning because it preserves more uncertainty and this leads to more accurate classification. For this purpose, we compared the results of implementing the proposed method to the majority vote as the most common and successful aggregation function in the literature on 10 medical data sets to show the better performance of the interval modeling and the proposed interval-based aggregation function in binary classification when it comes to ensemble learning. The results confirm the good performance of our proposed approach.

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Similarity measure for aggregated fuzzy numbers from interval-valued data

This paper presents a method to compute the degree of similarity between two aggregated fuzzy numbers from intervals using the Interval Agreement Approach (IAA). The similarity measure proposed within this study contains several features and attributes, of which are novel to aggregated fuzzy numbers. The attributes completely redefined or modified within this study include area, perimeter, centroids, quartiles and the agreement ratio. The recommended weighting for each feature has been learned using Principal Component Analysis (PCA). Furthermore, an illustrative example is provided to detail the application and potential future use of the similarity measure.

cs.AI↗

Data-Driven Regular Expressions Evolution for Medical Text Classification Using Genetic Programming

In medical fields, text classification is one of the most important tasks that can significantly reduce human workload through structured information digitization and intelligent decision support. Despite the popularity of learning-based text classification techniques, it is hard for human to understand or manually fine-tune the classification results for better precision and recall, due to the black box nature of learning. This study proposes a novel regular expression-based text classification method making use of genetic programming (GP) approaches to evolve regular expressions that can classify a given medical text inquiry with satisfactory precision and recall while allow human to read the classifier and fine-tune accordingly if necessary. Given a seed population of regular expressions (can be randomly initialized or manually constructed by experts), our method evolves a population of regular expressions according to chosen fitness function, using a novel regular expression syntax and a series of carefully chosen reproduction operators. Our method is evaluated with real-life medical text inquiries from an online healthcare provider and shows promising performance. More importantly, our method generates classifiers that can be fully understood, checked and updated by medical doctors, which are fundamentally crucial for medical related practices.

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Machine learning with incomplete datasets using multi-objective optimization models

Machine learning techniques have been developed to learn from complete data. When missing values exist in a dataset, the incomplete data should be preprocessed separately by removing data points with missing values or imputation. In this paper, we propose an online approach to handle missing values while a classification model is learnt. To reach this goal, we develop a multi-objective optimization model with two objective functions for imputation and model selection. We also propose three formulations for imputation objective function. We use an evolutionary algorithm based on NSGA II to find the optimal solutions as the Pareto solutions. We investigate the reliability and robustness of the proposed model using experiments by defining several scenarios in dealing with missing values and classification. We also describe how the proposed model can contribute to medical informatics. We compare the performance of three different formulations via experimental results. The proposed model results get validated by comparing with a comparable literature.

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Methods of ranking for aggregated fuzzy numbers from interval-valued data

This paper primarily presents two methods of ranking aggregated fuzzy numbers from intervals using the Interval Agreement Approach (IAA). The two proposed ranking methods within this study contain the combination and application of previously proposed similarity measures, along with attributes novel to that of aggregated fuzzy numbers from interval-valued data. The shortcomings of previous measures, along with the improvements of the proposed methods, are illustrated using both a synthetic and real-world application. The real-world application regards the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) algorithm, modified to include both the previous and newly proposed methods.

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A Hybrid Pricing and Cutting Approach for the Multi-Shift Full Truckload Vehicle Routing Problem

Full truckload transportation (FTL) in the form of freight containers represents one of the most important transportation modes in international trade. Due to large volume and scale, in FTL, delivery time is often less critical but cost and service quality are crucial. Therefore, efficiently solving large scale multiple shift FTL problems is becoming more and more important and requires further research. In one of our earlier studies, a set covering model and a three-stage solution method were developed for a multi-shift FTL problem. This paper extends the previous work and presents a significantly more efficient approach by hybridising pricing and cutting strategies with metaheuristics (a variable neighbourhood search and a genetic algorithm). The metaheuristics were adopted to find promising columns (vehicle routes) guided by pricing and cuts are dynamically generated to eliminate infeasible flow assignments caused by incompatible commodities. Computational experiments on real-life and artificial benchmark FTL problems showed superior performance both in terms of computational time and solution quality, when compared with previous MIP based three-stage methods and two existing metaheuristics. The proposed cutting and heuristic pricing approach can efficiently solve large scale real-life FTL problems.

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Multicriteria Group Decision-Making Under Uncertainty Using Interval Data and Cloud Models

In this study, we propose a multicriteria group decision making (MCGDM) algorithm under uncertainty where data is collected as intervals. The proposed MCGDM algorithm aggregates the data, determines the optimal weights for criteria and ranks alternatives with no further input. The intervals give flexibility to experts in assessing alternatives against criteria and provide an opportunity to gain maximum information. We also propose a novel method to aggregate expert judgements using cloud models. We introduce an experimental approach to check the validity of the aggregation method. After that, we use the aggregation method for an MCGDM problem. Here, we find the optimal weights for each criterion by proposing a bilevel optimisation model. Then, we extend the technique for order of preference by similarity to ideal solution (TOPSIS) for data based on cloud models to prioritise alternatives. As a result, the algorithm can gain information from decision makers with different levels of uncertainty and examine alternatives with no more information from decision-makers. The proposed MCGDM algorithm is implemented on a case study of a cybersecurity problem to illustrate its feasibility and effectiveness. The results verify the robustness and validity of the proposed MCGDM using sensitivity analysis and comparison with other existing algorithms.

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Transfer learning to enhance amenorrhea status prediction in cancer and fertility data with missing values

Collecting sufficient labelled training data for health and medical problems is difficult (Antropova, et al., 2018). Also, missing values are unavoidable in health and medical datasets and tackling the problem arising from the inadequate instances and missingness is not straightforward (Snell, et al. 2017, Sterne, et al. 2009). However, machine learning algorithms have achieved significant success in many real-world healthcare problems, such as regression and classification and these techniques could possibly be a way to resolve the issues.

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THCluster: herb supplements categorization for precision traditional Chinese medicine

There has been a continuing demand for traditional and complementary medicine worldwide. A fundamental and important topic in Traditional Chinese Medicine (TCM) is to optimize the prescription and to detect herb regularities from TCM data. In this paper, we propose a novel clustering model to solve this general problem of herb categorization, a pivotal task of prescription optimization and herb regularities. The model utilizes Random Walks method, Bayesian rules and Expectation Maximization(EM) models to complete a clustering analysis effectively on a heterogeneous information network. We performed extensive experiments on the real-world datasets and compared our method with other algorithms and experts. Experimental results have demonstrated the effectiveness of the proposed model for discovering useful categorization of herbs and its potential clinical manifestations.

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Measuring agreement on linguistic expressions in medical treatment scenarios

Quality of life assessment represents a key process of deciding treatment success and viability. As such, patients' perceptions of their functional status and well-being are important inputs for impairment assessment. Given that patient completed questionnaires are often used to assess patient status and determine future treatment options, it is important to know the level of agreement of the words used by patients and different groups of medical professionals. In this paper, we propose a measure called the Agreement Ratio which provides a ratio of overall agreement when modelling words through Fuzzy Sets (FSs). The measure has been specifically designed for assessing this agreement in fuzzy sets which are generated from data such as patient responses. The measure relies on using the Jaccard Similarity Measure for comparing the different levels of agreement in the FSs generated.

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Uncertainty measures for probabilistic hesitant fuzzy sets in multiple criteria decision making

This contribution reviews critically the existing entropy measures for probabilistic hesitant fuzzy sets (PHFSs), and demonstrates that these entropy measures fail to effectively distinguish a variety of different PHFSs in some cases. In the sequel, we develop a new axiomatic framework of entropy measures for probabilistic hesitant fuzzy elements (PHFEs) by considering two facets of uncertainty associated with PHFEs which are known as fuzziness and nonspecificity. Respect to each kind of uncertainty, a number of formulae are derived to permit flexible selection of PHFE entropy measures. Moreover, based on the proposed PHFE entropy measures, we introduce some entropy-based distance measures which are used in the portion of comparative analysis.

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Higher order hesitant fuzzy Choquet integral operator and its application to multiple criteria decision making

Generally, the criteria involved in a decision making problem are interactive or inter-dependent, and therefore aggregating them by the use of traditional operators which are based on additive measures is not logical. This verifies that we have to implement fuzzy measures for modelling the interaction phenomena among the criteria.On the other hand, based on the recent extension of hesitant fuzzy set, called higher order hesitant fuzzy set (HOHFS) which allows the membership of a given element to be defined in forms of several possible generalized types of fuzzy set, we encourage to propose the higher order hesitant fuzzy (HOHF) Choquet integral operator. This concept not only considers the importance of the higher order hesitant fuzzy arguments, but also it can reflect the correlations among those arguments. Then,a detailed discussion on the aggregation properties of the HOHF Choquet integral operator will be presented.To enhance the application of HOHF Choquet integral operator in decision making, we first assess the appropriate energy policy for the socio-economic development. Then, the efficiency of the proposed HOHF Choquet integral operator-based technique over a number of exiting techniques is further verified by employing another decision making problem associated with the technique of TODIM (an acronym in Portuguese of Interactive and Multicriteria Decision Making).

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Learning Regular Expressions for Interpretable Medical Text Classification Using a Pool-based Simulated Annealing and Word-vector Models

In this paper, we propose a rule-based engine composed of high quality and interpretable regular expressions for medical text classification. The regular expressions are auto generated by a constructive heuristic method and optimized using a Pool-based Simulated Annealing (PSA) approach. Although existing Deep Neural Network (DNN) methods present high quality performance in most Natural Language Processing (NLP) applications, the solutions are regarded as uninterpretable black boxes to humans. Therefore, rule-based methods are often introduced when interpretable solutions are needed, especially in the medical field. However, the construction of regular expressions can be extremely labor-intensive for large data sets. This research aims to reduce the manual efforts while maintaining high-quality solutions

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Fuzzy C-means-based scenario bundling for stochastic service network design

Stochastic service network designs with uncertain demand represented by a set of scenarios can be modelled as a large-scale two-stage stochastic mixed-integer program (SMIP). The progressive hedging algorithm (PHA) is a decomposition method for solving the resulting SMIP. The computational performance of the PHA can be greatly enhanced by decomposing according to scenario bundles instead of individual scenarios. At the heart of bundle-based decomposition is the method for grouping the scenarios into bundles. In this paper, we present a fuzzy c-means-based scenario bundling method to address this problem. Rather than full membership of a bundle, which is typically the case in existing scenario bundling strategies such as k-means, a scenario has partial membership in each of the bundles and can be assigned to more than one bundle in our method.

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Using simulation to incorporate dynamic criteria into multiple criteria decision-making

In this paper, we present a case study demonstrating how dynamic and uncertain criteria can be incorporated into a multicriteria analysis with the help of discrete event simulation. The simulation guided multicriteria analysis can include both monetary and non-monetary criteria that are static or dynamic, whereas standard multi criteria analysis only deals with static criteria and cost benefit analysis only deals with static monetary criteria. The dynamic and uncertain criteria are incorporated by using simulation to explore how the decision options perform. The results of the simulation are then fed into the multicriteria analysis. By enabling the incorporation of dynamic and uncertain criteria, the dynamic multiple criteria analysis was able to take a unique perspective of the problem. The highest ranked option returned by the dynamic multicriteria analysis differed from the other decision aid techniques.

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Multi-objective semi-supervised clustering to identify health service patterns for injured patients

This study develops a pattern recognition method that identifies patterns based on their similarity and their association with the outcome of interest. The practical purpose of developing this pattern recognition method is to group patients, who are injured in transport accidents, in the early stages post-injury. This grouping is based on distinctive patterns in health service use within the first week post-injury. The groups also provide predictive information towards the total cost of medication process. As a result, the group of patients who have undesirable outcomes are identified as early as possible based health service use patterns.

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Imputation techniques on missing values in breast cancer treatment and fertility data

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of modelling if handled improperly. Imputing missing values provides an opportunity to resolve the issue. Conventional imputation methods adopt simple statistical analysis, such as mean imputation or discarding missing cases, which have many limitations and thus degrade the performance of learning. This study examines a series of machine learning based imputation methods and suggests an efficient approach to in preparing a good quality breast cancer (BC) dataset, to find the relationship between BC treatment and chemotherapy-related amenorrhoea, where the performance is evaluated with the accuracy of the prediction.

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