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V. Salari

Publications and source records attributed to V. Salari.

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Generalized Deutsch-Jozsa Algorithm for Applications in Data Classification, Logistic Regression, and Quantum Key Distribution

We present a generalized Deutsch-Jozsa (DJ) quantum algorithm that not only determines both the global type of an unknown Boolean function (constant or balanced) but also determines explicit output values of the function in a single oracle query. Unlike the original DJ algorithm, which identifies only whether a function is constant or balanced, our generalization retrieves actual function output values at the same time with using a Bell state as ancilla. This makes a richer function characterization with minimal queries to have practical quantum advantages, e.g. data classification, logistic regression, and quantum cryptography.

quant-ph

Optimal Quantum Circuit Design via Unitary Neural Networks

The process of translating a quantum algorithm into a form suitable for implementation on a quantum computing platform is crucial but yet challenging. This entails specifying quantum operations with precision, a typically intricate task. In this paper, we present an alternative approach: an automated method for synthesizing the functionality of a quantum algorithm into a quantum circuit model representation. Our methodology involves training a neural network model using diverse input-output mappings of the quantum algorithm. We demonstrate that this trained model can effectively generate a quantum circuit model equivalent to the original algorithm. Remarkably, our observations indicate that the trained model achieves near-perfect mapping of unseen inputs to their respective outputs.

quant-ph

Towards non-invasive cancer diagnostics and treatment based on electromagnetic fields, optomechanics and microtubules

In this paper, we discuss biological effects of electromagnetic (EM) fields in the context of cancer biology. In particular, we review the nanomechanical properties of microtubules (MTs), the latter being one of the most successful targets for cancer therapy. We propose an investigation on the coupling of electromagnetic radiation to mechanical vibrations of MTs as an important basis for biological and medical applications. In our opinion optomechanical methods can accurately monitor and control the mechanical properties of isolated MTs in a liquid environment. Consequently, studying nanomechanical properties of MTs may give useful information for future applications to diagnostic and therapeutic technologies involving non-invasive externally applied physical fields. For example, electromagnetic fields or high intensity ultrasound can be used therapeutically avoiding harmful side effects of chemotherapeutic agents or classical radiation therapy.

physics.med-ph

Monitoring Microtubule Mechanical Vibrations via Optomechanical Coupling

The possible disruption of a microtubule during mitosis can control the duplication of a cancer cell. Cancer detection and treatment may be possible based on the detection and control of microtubule mechanical oscillations in cells through external fields (e.g. electromagnetic or ultrasound). However, little is known about the dynamic (high-frequency) mechanical properties of microtubules. Here we propose to control the vibrations of a doubly clamped microtubule by tip electrodes and to detect its motion via the optomechanical coupling between the vibrational modes of the microtubule and an optical cavity. In the presence of a red-detuned strong pump laser, this coupling leads to optomechanical induced transparency of an optical probe field, which can be detected with state-of the art technology. The center frequency and linewidth of the transparency peak give the resonance frequency and damping rate of the microtubule respectively, while the height of the peak reveals information about the microtubule-cavity field coupling. Our method should yield new knowledge about the physical properties of microtubules, which will enhance our capability to design physical cancer treatment protocols as alternatives to chemotherapeutic drugs.

quant-ph

A Simulation for Neurophotonic Quantum Computation in Visual Pathways

One of the answers to the measurement problem in quantum theory is given by the Copenhagen-Interpretation of quantum theory (i.e. orthodox quantum theory) in which the wave function collapse happens in (by) the mind of observer. In fact, at first, great scientists like Von Neumann, London, Bauer and Wigner (initially) believed that the wave function collapse occurs in the brain or is caused by the consciousness of observer. However, this issue has been stayed yet very controversial. In fact, there are many challenging discussions about the survival of quantum effects in microscopic structures of the human brain, which is mainly because of quick decoherence of quantum states due to hot, wet and noisy environment of the brain that forbids long life coherence for brain processing. Nevertheless, there are also several arguments and evidences that emergence of large coherent states is feasible in the brain. In this paper, our approach is based on the latter in which macroscopic quantum states are probable in the human brain. Here, we simulate the delayed luminescence of photons in neurons with a Brassard-like teleportation circuit, i.e. equivalent to the transfer of quantum states of photons through the visual pathways from retina to the visual cortex. Indeed, our simulation considers both classical and quantum mechanical aspects of processing in neurons. As a result and based on our simulation, it is possible for our brain to receive the exact quantum states of photons in the visual cortex to be collapsed by our consciousness, which supports the Copenhagen-Interpretation of measurement problem in quantum theory.

q-bio.OT

Experimental Investigation of Distant Cellular Interaction among Adipose Derived Stem-Cells

In addition to chemical and mechanical interactions between cells electromagnetic field produced by cells has been considered as another form of signaling for cell-cell communication. The aim of this study is evaluation of electromagnetic effects on viability of Adipose-derived stem cells (ADSCs) without co-culturing. In this study, stem cells were isolated from human adipose tissue enzymatically and proliferated in monolayer culture. Then, 5.(10^4) adipose-derived stem cells were cultured in each well of the test plate. In the first row (4 wells), ADSCs as inducer cells were cultured in DMEM1 with 10 ng/ml Fibroblast growth factor (FGF). In adjacent and the last rows, ADSCs were cultured without FGF (as detector cells). After the three and five days the viability of cells were evaluated. Moreover, ADSCs were cultured in the same conditions but the inducer cells were placed once in the UV-filter tube and once in the quartz tube to see whether there is electromagnetic interaction among cells. Inducer cells caused significant cell proliferation in adjacent row cells (p- value<0.01) in the fifth day. However, using the UV-filter tube and quartz tube both reduced the effect of inducer cells on adjacent cells significantly. As a conclusion, we could detect distant cellular interaction (DCI) among adipose derived stem cells (ADSCs), but it was not electromagnetic signaling. Our results show that ADSCs affect each other via volatile signaling as a chemical distant cellular interaction (CDCI).

q-bio.OT

Quantum Decoherence Timescales for Ionic Superposition States in Ion Channels

There are many controversial and challenging discussions about quantum effects in microscopic structures in neurons of the human brain. The challenge is mainly because of quick decoherence of quantum states due to hot, wet and noisy environment of the brain which forbids long life coherence for brain processing. Despite these critical discussions, there are only a few number of published papers about numerical aspects of decoherence in neurons. Perhaps the most important issue is offered by Max Tegmark who has calculated decoherence times for the systems of "ions" and "microtubules" in neurons of the brain. In fact, Tegmark did not consider ion channels which are responsible for ions displacement through the membrane and are the building blocks of electrical membrane signals in the nervous system. Here, we would like to re-investigate decoherence times for ionic superposition states by using the data obtained via molecular dynamics simulations. Our main approach is according to what Tegmark has used before. In fact, Tegmark didn't consider the ion channel structure and his estimates are only simple approximations. In this paper, we focus on the small nano-scale part of KcsA ion channels which is called "selectivity filter" and has a key role in the operation of an ion channel. Our results for superposition states of potassium ions indicate that decoherence times are in the order of picoseconds which are 10-100 million times bigger than the order calculated by Tegmark. This decoherence time is still not enough for cognitive processing in the brain, however it can be adequate for quantum states of cooled ions in the filter to leave their quantum traces on the filter and action potentials.

physics.bio-ph

Emission of Mitochondrial Biophotons and their Effect on Electrical Activity of Membrane via Microtubules

In this paper we argue that, in addition to electrical and chemical signals propagating in the neurons of the brain, signal propagation takes place in the form of biophoton production. This statement is supported by recent experimental confirmation of photon guiding properties of a single neuron. We have investigated the interaction of mitochondrial biophotons with microtubules from a quantum mechanical point of view. Our theoretical analysis indicates that the interaction of biophotons and microtubules causes transitions/fluctuations of microtubules between coherent and incoherent states. A significant relationship between the fluctuation function of microtubules and alpha-EEG diagrams is elaborated on in this paper. We argue that the role of biophotons in the brain merits special attention.

physics.bio-ph

Visible light induced ocular delayed bioluminescence as a possible origin of negative afterimage

The delayed luminescence of biological tissues is an ultraweak reemission of absorbed photons after exposure to external monochromatic or white light illumination. Recently, Wang, Bókkon, Dai and Antal (Brain Res. 2011) presented the first experimental proof of the existence of spontaneous ultraweak biophoton emission and visible light induced delayed ultraweak photon emission from in vitro freshly isolated rat's whole eye, lens, vitreous humor and retina. Here, we suggest that the photobiophysical source of negative afterimage can also occur within the eye by delayed bioluminescent photons. In other words, when we stare at a colored (or white) image for few seconds, external photons can induce excited electronic states within different parts of the eye that is followed by a delayed reemission of absorbed photons for several seconds. Finally, these reemitted photons can be absorbed by nonbleached photoreceptors that produce a negative afterimage. Although this suggests the photobiophysical source of negative afterimages is related retinal mechanisms, cortical neurons have also essential contribution in the interpretation and modulation of negative afterimages.

physics.bio-ph

Plausibility of Quantum Coherent States in Biological Systems

In this paper we briefly discuss the necessity of using quantum mechanics as a fundamental theory applicable to some key functional aspects of biological systems. This is especially relevant to three important parts of a neuron in the human brain, namely the cell membrane, microtubules (MT) and ion channels. We argue that the recently published papers criticizing the use of quantum theory in these systems are not convincing.

physics.bio-ph

Emergence of Intrinsic Representations of Images by Feedforward and Feedback Processes and Bioluminescent Photons in Early Retinotopic Areas

Recently, we put forwarded a redox molecular hypothesis involving the natural biophysical substrate of visual perception and imagery. Here, we explicitly propose that the feedback and feedforward iterative operation processes can be interpreted in terms of a homunculus looking at the biophysical picture in our brain during visual imagery. We further propose that the brain can use both picture-like and language-like representation processes. In our interpretation, visualization (imagery) is a special kind of representation i.e., visual imagery requires a peculiar inherent biophysical (picture-like) mechanism. We also conjecture that the evolution of higher levels of complexity made the biophysical picture representation of the external visual world possible by controlled redox and bioluminescent nonlinear (iterative) biochemical reactions in the V1 and V2 areas during visual imagery. Our proposal deals only with the primary level of visual representation (i.e. perceived "scene").

q-bio.NC

Estimation of the number of biophotons involved in the visual perception of a single-object image: Biophoton intensity can be considerably higher inside cells than outside

Recently, we have proposed a redox molecular hypothesis about the natural biophysical substrate of visual perception and imagery (Bókkon, 2009. BioSystems; Bókkon and D'Angiulli, 2009. Bioscience Hypotheses). Namely, the retina transforms external photon signals into electrical signals that are carried to the V1 (striate cortex). Then, V1 retinotopic electrical signals (spike-related electrical signals along classical axonal-dendritic pathways) can be converted into regulated ultraweak bioluminescent photons (biophotons) through redox processes within retinotopic visual neurons that make it possible to create intrinsic biophysical pictures during visual perception and imagery. However, the consensus opinion is to consider biophotons as by-products of cellular metabolism. This paper argues that biophotons are not by-products, other than originating from regulated cellular radical/redox processes. It also shows that the biophoton intensity can be considerably higher inside cells than outside. Our simple calculations, within a level of accuracy, suggest that the real biophoton intensity in retinotopic neurons may be sufficient for creating intrinsic biophysical picture representation of a single-object image during visual perception.

q-bio.NC

On the Theoretical Possibility of Quantum Visual Information Transfer to the Human Brain

The feasibility of wave function collapse in the human brain has been the subject of vigorous scientific debates since the advent of quantum theory. Scientists like Von Neumann, London, Bauer and Wigner (initially) believed that wave function collapse occurs in the brain or is caused by the mind of the observer. It is a legitimate question to ask how human brain can receive subtle external visual quantum information intact when it must pass through very noisy and complex pathways from the eye to the brain? There are several approaches to investigate information processing in the brain, each of which presents a different set of conclusions. Penrose and Hameroff have hypothesized that there is quantum information processing inside the human brain whose material substrate involves microtubules and consciousness is the result of a collective wavefunction collapse occurring in these structures. Conversely, Tegmark stated that owing to thermal decoherence there cannot be any quantum processing in neurons of the brain and processing in the brain must be classical for cognitive processes. However, Rosa and Faber presented an argument for a middle way which shows that none of the previous authors are completely right and despite the presence of decoherence, it is still possible to consider the brain to be a quantum system. Additionally, Thaheld, has concluded that quantum states of photons do collapse in the human eye and there is no possibility for collapse of visual quantum states in the brain and thus there is no possibility for the quantum state reduction in the brain. In this paper we conclude that if we accept the main essence of the above approaches taken together, each of them can provide a different part of a teleportation mechanism.

quant-ph