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Vanja Nikolić

Publications and source records attributed to Vanja Nikolić.

At least 37 records · Page 2Linked to original sources

Mixed approximation of nonlinear acoustic equations: Well-posedness and a priori error analysis

Accurate simulation of nonlinear acoustic waves is essential for the continued development of a wide range of (high-intensity) focused ultrasound applications. This article explores mixed finite element formulations of classical strongly damped quasilinear models of ultrasonic wave propagation; the Kuznetsov and Westervelt equations. Such formulations allow simultaneous retrieval of the acoustic particle velocity and either the pressure or acoustic velocity potential, thus characterizing the entire ultrasonic field at once. Using non-standard energy analysis and a fixed-point technique, we establish sufficient conditions for the well-posedness, stability, and optimal a priori errors in the energy norm for the semi-discrete equations. For the Westervelt equation, we also determine the conditions under which the error bounds can be made uniform with respect to the involved strong dissipation parameter. A byproduct of this analysis is the convergence rate for the inviscid (undamped) Westervelt equation in mixed form. Additionally, we discuss convergence in the $L^q(Ω)$ norm for the involved scalar quantities, where $q$ depends on the spatial dimension. Finally, computer experiments for the Raviart--Thomas (RT) and Brezzi--Douglas--Marini (BDM) elements are performed to confirm the theoretical findings.

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Analysis of general shape optimization problems in nonlinear acoustics

In various biomedical applications, precise focusing of nonlinear ultrasonic waves is crucial for efficiency and safety of the involved procedures. This work analyzes a class of shape optimization problems constrained by general quasi-linear acoustic wave equations that arise in high-intensity focused ultrasound (HIFU) applications. Within our theoretical framework, the Westervelt and Kuznetsov equations of nonlinear acoustics are obtained as particular cases. The quadratic gradient nonlinearity, specific to the Kuznetsov equation, requires special attention throughout. To prove the existence of the Eulerian shape derivative, we successively study the local well-posedness and regularity of the forward problem, uniformly with respect to shape variations, and prove that it does not degenerate under the hypothesis of small initial and boundary data. Additionally, we prove Hölder-continuity of the acoustic potential with respect to domain deformations. We then derive and analyze the corresponding adjoint problems for several different cost functionals of practical interest and conclude with the expressions of well-defined shape derivatives.

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Time-fractional Moore-Gibson-Thompson equations

In this paper, we consider several time-fractional generalizations of the Jordan-Moore-Gibson-Thompson (JMGT) equations in nonlinear acoustics as well as their linear Moore-Gibson-Thompson (MGT) versions. Following the procedure described in Jordan (2014), these time-fractional acoustic equations are derived from four fractional versions of the Maxwell-Cattaneo law in Compte and Metzler (1997). Additionally to providing well-posedness results for each of them, we also study the respective limits as the fractional order tends to one, leading to the classical third order in time (J)MGT equation.

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Determining kernels in linear viscoelasticity

In this work, we investigate the inverse problem of determining the kernel functions that best describe the mechanical behavior of a complex medium modeled by a general nonlocal viscoelastic wave equation. To this end, we minimize a tracking-type data misfit function under this PDE constraint. We perform the well-posedness analysis of the state and adjoint problems and, using these results, rigorously derive the first-order sensitivities. Numerical experiments in a three-dimensional setting illustrate the method.

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Parabolic approximation of quasilinear wave equations with applications in nonlinear acoustics

This work deals with the convergence analysis of parabolic perturbations to quasilinear wave equations on smooth bounded domains. In particular, we consider wave equations with nonlinearities of quadratic type, which cover the two classical models of nonlinear acoustics, the Westervelt and Kuznetsov equations. By employing a high-order energy analysis, we obtain convergence of their solutions to the corresponding inviscid equations' solutions in the standard energy norm with a linear rate, assuming small data and a sufficiently short time. The smallness of initial data can, however, be imposed in a lower-order norm than the one needed in the energy analysis. It arises only from ensuring the non-degeneracy of the studied wave equations. In addition, we address the open questions of local well-posedness of the two classical models on bounded domains with a non-negative, possibly vanishing sound diffusivity.

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A phase-field approach to shape and topology optimization of acoustic waves in dissipative media

We investigate the problem of finding the optimal shape and topology of a system of acoustic lenses in a dissipative medium. The sound propagation is governed by a general semilinear strongly damped wave equation. We introduce a phase-field formulation of this problem through diffuse interfaces between the lenses and the surrounding fluid. The resulting formulation is shown to be well-posed and we prove that the corresponding optimization problem has a minimizer. By analyzing properties of the reduced objective functional and well-posedness of the adjoint problem, we rigorously derive first-order optimality conditions for this problem. Additionally, we consider the $Γ$-limit of the reduced objective functional and in this way establish a relation between the diffuse interface problem and a perimeter-regularized sharp interface shape optimization problem.

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Local well-posedness of a coupled Westervelt-Pennes model of nonlinear ultrasonic heating

High-Intensity Focused Ultrasound (HIFU) waves are known to induce localized heat to a targeted area during medical treatments. In turn, the rise in temperature influences their speed of propagation. This coupling affects the position of the focal region as well as the achieved pressure and temperature values. In this work, we investigate a mathematical model of nonlinear ultrasonic heating based on the Westervelt wave equation coupled to the Pennes bioheat equation that captures this so-called thermal lensing effect. We prove that this quasi-linear model is well-posed locally in time and does not degenerate under a smallness assumption on the pressure data.

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A discontinuous Galerkin coupling for nonlinear elasto-acoustics

Inspired by medical applications of high-intensity ultrasound, we study a coupled elasto-acoustic problem with general acoustic nonlinearities of quadratic type as they arise, for example, in the Westervelt and Kuznetsov equations of nonlinear acoustics. We derive convergence rates in the energy norm of a finite element approximation to the coupled problem in a setting that involves different acoustic materials and hence jumps within material parameters. A subdomain-based discontinuous Galerkin approach realizes the acoustic-acoustic coupling of different materials. At the same time, elasto-acoustic interface conditions are used for a mutual exchange of forces between the different models. Numerical simulations back up the theoretical findings in a three-dimensional setting with academic test cases as well as in an application-oriented simulation, where the modeling of human tissue as an elastic versus an acoustic medium is compared.

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The inviscid limit of third-order linear and nonlinear acoustic equations

We analyze the behavior of third-order in time linear and nonlinear sound waves in thermally relaxing fluids and gases as the sound diffusivity vanishes. The nonlinear acoustic propagation is modeled by the Jordan--Moore--Gibson--Thompson equation both in its Westervelt and in its Kuznetsov-type forms, that is, including quadratic nonlinearities of the type $(u^2)_{tt}$ and $ (u_t^2 + |\nabla u|^2)_t$. As it turns out, sufficiently smooth solutions of these equations converge in the energy norm to the solutions of the corresponding inviscid models at a linear rate. Numerical experiments illustrate our theoretical findings.

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Asymptotic behavior of nonlinear sound waves in inviscid media with thermal and molecular relaxation

Ultrasonic propagation through media with thermal and molecular relaxation can be modeled by third-order in time nonlinear wave-like equations with memory. This paper investigates the asymptotic behavior of a Cauchy problem for such a model, the nonlocal Jordan--Moore--Gibson--Thompson equation, in the so-called critical case, which corresponds to propagation in inviscid fluids. The memory has an exponentially fading character and type I, meaning that involves only the acoustic velocity potential. A major challenge in the global analysis is that the linearized equation's decay estimates are of regularity-loss type. As a result, the classical energy methods fail to work for the nonlinear problem. To overcome this difficulty, we construct appropriate time-weighted norms, where weights can have negative exponents. These problem-tailored norms create artificial damping terms that help control the nonlinearity and the loss of derivatives, and ultimately allow us to discover the model's asymptotic behavior.

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Mathematical analysis of memory effects and thermal relaxation in nonlinear sound waves on unbounded domains

Motivated by the propagation of nonlinear sound waves through relaxing hereditary media, we study a nonlocal third-order Jordan-Moore-Gibson-Thompson acoustic wave equation. Under the assumption that the relaxation kernel decays exponentially, we prove local well-posedness in unbounded two- and three-dimensional domains. In addition, we show that the solution of the three-dimensional model exists globally in time for small and smooth data, while the energy of the system decays polynomially.

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On the Jordan-Moore-Gibson-Thompson wave equation in hereditary fluids with quadratic gradient nonlinearity

We prove global solvability of the third-order in time Jordan-More-Gibson-Thompson acoustic wave equation with memory in $\mathbb{R}^n$, where $n \geq 3$. This wave equation models ultrasonic propagation in relaxing hereditary fluids and incorporates both local and cumulative nonlinear effects. The proof of global solvability is based on a sequence of high-order energy bounds that are uniform in time, and derived under the assumption of an exponentially decaying memory kernel and sufficiently small and regular initial data.

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A high-order discontinuous Galerkin method for nonlinear sound waves

We propose a high-order discontinuous Galerkin scheme for nonlinear acoustic waves on polytopic meshes. To model sound propagation with and without losses, we use Westervelt's nonlinear wave equation with and without strong damping. Challenges in the numerical analysis lie in handling the nonlinearity in the model, which involves the derivatives in time of the acoustic velocity potential, and in preventing the equation from degenerating. We rely in our approach on the Banach fixed-point theorem combined with a stability and convergence analysis of a linear wave equation with a variable coefficient in front of the second time derivative. By doing so, we derive an a priori error estimate for Westervelt's equation in a suitable energy norm for the polynomial degree $p \geq 2$. Numerical experiments carried out in two-dimensional settings illustrate the theoretical convergence results. In addition, we demonstrate efficiency of the method in a three-dimensional domain with varying medium parameters, where we use the discontinuous Galerkin approach in a hybrid way.

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On the Jordan-Moore-Gibson-Thompson equation: well-posedness with quadratic gradient nonlinearity and singular limit for vanishing relaxation time

In this paper, we consider the Jordan-Moore-Gibson-Thompson equation, a third order in time wave equation describing the nonlinear propagation of sound that avoids the infinite signal speed paradox of classical second order in time strongly damped models of nonlinear acoustics, such as the Westervelt and the Kuznetsov equation. We show well-posedness in an acoustic velocity potential formulation with and without gradient nonlinearity, corresponding to the Kuznetsov and the Westervelt nonlinearities, respectively. Moreover, we consider the limit as the parameter of the third order time derivative that plays the role of a relaxation time tends to zero, which again leads to the classical Kuznetsov and Westervelt models. To this end, we establish appropriate energy estimates for the linearized equations and employ fixed-point arguments for well-posedness of the nonlinear equations. The theoretical results are illustrated by numerical experiments.

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Local and nonlocal phase-field models of tumor growth and invasion due to ECM degradation

We present and analyze new multi-species phase-field mathematical models of tumor growth and ECM invasion. The local and nonlocal mathematical models describe the evolution of volume fractions of tumor cells, viable cells (proliferative and hypoxic cells), necrotic cells, and the evolution of MDE and ECM, together with chemotaxis, haptotaxis, apoptosis, nutrient distribution, and cell-to-matrix adhesion. We provide a rigorous proof of the existence of solutions of the coupled system with gradient-based and adhesion-based haptotaxis effects. In addition, we discuss finite element discretizations of the model, and we present the results of numerical experiments designed to show the relative importance and roles of various effects, including cell mobility, proliferation, necrosis, hypoxia, and nutrient concentration on the generation of MDEs and the degradation of the ECM.

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A priori error estimates for the finite element approximation of Westervelt's quasilinear acoustic wave equation

We study the spatial discretization of Westervelt's quasilinear strongly damped wave equation by piecewise linear finite elements. Our approach employs the Banach fixed-point theorem combined with a priori analysis of a linear wave model with variable coefficients. Degeneracy of the semi-discrete Westervelt equation is avoided by relying on the inverse estimates for finite element functions and the stability and approximation properties of the interpolation operator. In this way, we obtain optimal convergence rates in $L^2$-based spatial norms for sufficiently small data and mesh size and an appropriate choice of initial approximations. Numerical experiments in a setting of a 1D channel as well as for a focused-ultrasound problem illustrate our theoretical findings.

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Self-adaptive absorbing boundary conditions for quasilinear acoustic wave propagation

We propose a self-adaptive absorbing technique for quasilinear ultrasound waves in two- and three-dimensional computational domains. As a model for the nonlinear ultrasound propagation in thermoviscous fluids, we employ Westervelt's wave equation solved for the acoustic velocity potential. The angle of incidence of the wave is computed based on the information provided by the wave-field gradient which is readily available in the finite element framework. The absorbing boundary conditions are then updated with the angle values in real time. Numerical experiments illustrate the accuracy and efficiency of the proposed method.

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Vanishing relaxation time limit of the Jordan--Moore--Gibson--Thompson wave equation with Neumann and absorbing boundary conditions

We study the Jordan--Moore--Gibson--Thompson (JMGT) equation, a third order in time wave equation that models nonlinear sound propagation, in the practically relevant setting of Neumann and absorbing boundary conditions. In the analysis, we pay special attention to dependencies on the coefficient $τ$ of the third order time derivative that plays the physical role of relaxation time. We establish local in time well-posedness and derive energy bounds that can be made independent of $τ$ under appropriate conditions. This fact allows us to pass to the limit $τ\to0$ and recover solutions of a classical model in nonlinear acoustics, the Westervelt equation, as singular limits of solutions to the JMGT equation.

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