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Vasileios E. Papageorgiou

Publications and source records attributed to Vasileios E. Papageorgiou.

8 recordsLinked to original sources

Optimal Allocation of Embedding Dimensions under Finite-Sample Constraints

The embedding dimension of categorical predictors is usually selected through heuristic tuning, although it directly affects model complexity, approximation quality, and finite-sample generalization. This paper formulates embedding dimension selection as a constrained allocation problem. The main contribution is to show that embedding capacity can be allocated across heterogeneous categorical predictors according to an explicit approximation-estimation tradeoff. We characterize approximation error through the singular-value tail of the latent category representation, while estimation error increases with total embedding complexity. Under a fixed global embedding budget and a tractable approximation model, this leads to a closed-form allocation rule in which the dimension assigned to each predictor is proportional to the square root of its approximation value relative to its parameter cost. Simulation experiments support the proposed approximation-estimation interpretation and show that the allocation rule improves budget efficiency relative to standard uniform and cardinality-based heuristics, particularly when the budget is binding and predictor heterogeneity is substantial. A real-data healthcare application further shows improvements in predictive accuracy and probabilistic calibration. Overall, the results establish embedding-dimension allocation as a principled finite-sample optimization problem rather than a purely heuristic modeling choice.

math.OC↗

Evaluating the Impact of Epidemic Control via State-Dependent Markovian Switching Modeling

We develop an exact finite-population stochastic framework for SIR epidemics evolving under Markovian switching between intervention regimes. The epidemic state is augmented by a finite phase component, allowing transmission, recovery, and direct immunity-acquisition rates to depend on the active regime. Phase-transition intensities may depend on the current epidemic state, so that policy escalation can react to the number of infectious individuals. Exploiting the monotonicity of the susceptible compartment, we derive level-wise recursions for the joint Laplace--Stieltjes transform and probability generating function of the extinction time and the number of infections generated before extinction. These recursions yield the infection-count distribution, conditional extinction-time transforms, and mixed moments linking epidemic duration and infection burden, while replacing a large global linear system with small phase-level solves. The framework is illustrated using weekly mpox incidence data from Luxembourg. A baseline one-phase SIR model is calibrated by maximum likelihood under a Poisson observation model. The calibrated baseline is then used for conditional comparisons of fixed control regimes, early versus delayed strict intervention, vaccination-supported control, and state-dependent escalation. The results show how switching mechanisms affect both the total number of infected individuals and the extinction time, including their dispersion. Since the switching mechanisms are specified rather than estimated from the intervention history, the results are conditional model-based comparisons rather than estimates of the historical effects of interventions in Luxembourg.

q-bio.PE↗

Multi-cancer detection using a computationally efficient CNN with transfer learning

This study introduces a computationally efficient convolutional neural network (CNN) architecture enhanced with transfer learning for multi-cancer detection using biomedical images. The proposed lightweight CNN model is designed to reduce computational complexity while maintaining high classification performance, making it suitable for deployment in resource-constrained environments. We evaluate this approach on three distinct tumor datasets comprising brain magnetic resonance imaging (MRI) and lung and kidney computed tomography (CT) scans. The model achieves test accuracy of 90.85 +- 2.22%, 98.64 +- 2.43% and 99.92 +- 0.08% for brain, lung, and kidney cancer classification, respectively, using 5-fold stratified cross-validation (CV). Transfer learning is employed by pretraining the model on one cancer type and fine-tuning it on the others, requiring only 20 additional epochs to achieve performance comparable to models trained from scratch. The fine-tuning process involves updating the classification part of the CNN and requires approximately 0.014 seconds per image per epoch using an NVIDIA GeForce GTX 960. Comparative evaluations show that the proposed model outperforms several state-of-the-art pretrained architectures, such as Xception, VGG16, VGG19, MobileNetV2 and DenseNet121. Overall, the model's effectiveness is evaluated across three types of cancer with distinct morphological characteristics, assessing its performance on both MRI and CT imaging modalities and demonstrating robust performance across diverse tasks and data types. These findings underscore the potential of streamlined deep learning (DL) frameworks in accelerating cancer diagnosis without sacrificing accuracy, especially in settings with limited computational resources.

cs.CV↗

Efficient Lung Ultrasound Severity Scoring Using Dedicated Feature Extractor

With the advent of the COVID-19 pandemic, ultrasound imaging has emerged as a promising technique for COVID-19 detection, due to its non-invasive nature, affordability, and portability. In response, researchers have focused on developing AI-based scoring systems to provide real-time diagnostic support. However, the limited size and lack of proper annotation in publicly available ultrasound datasets pose significant challenges for training a robust AI model. This paper proposes MeDiVLAD, a novel pipeline to address the above issue for multi-level lung-ultrasound (LUS) severity scoring. In particular, we leverage self-knowledge distillation to pretrain a vision transformer (ViT) without label and aggregate frame-level features via dual-level VLAD aggregation. We show that with minimal finetuning, MeDiVLAD outperforms conventional fully-supervised methods in both frame- and video-level scoring, while offering classification reasoning with exceptional quality. This superior performance enables key applications such as the automatic identification of critical lung pathology areas and provides a robust solution for broader medical video classification tasks.

eess.IV↗

Seeking the Truth Beyond the Data. An Unsupervised Machine Learning Approach

Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The goal of this process is to provide a useful aid to the researcher that will help her/him to identify patterns among the data. Dealing with large databases, such patterns may not be easily detectable without the contribution of a clustering algorithm. This article provides a deep description of the most widely used clustering methodologies accompanied by useful presentations concerning suitable parameter selection and initializations. Simultaneously, this article not only represents a review highlighting the major elements of examined clustering techniques but emphasizes the comparison of these algorithms' clustering efficiency based on 3 datasets, revealing their existing weaknesses and capabilities through accuracy and complexity, during the confrontation of discrete and continuous observations. The produced results help us extract valuable conclusions about the appropriateness of the examined clustering techniques in accordance with the dataset's size.

stat.ML↗

A convolutional neural network of low complexity for tumor anomaly detection

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several machine learning and artificial intelligence methodologies has been employed aiming to provide trustworthy helping tools that will contribute efficiently to this attempt. In this article, we present a low-complexity convolutional neural network architecture for tumor classification enhanced by a robust image augmentation methodology. The effectiveness of the presented deep learning model has been investigated based on 3 datasets containing brain, kidney and lung images, showing remarkable diagnostic efficiency with classification accuracies of 99.33%, 100% and 99.7% for the 3 datasets respectively. The impact of the augmentation preprocessing step has also been extensively examined using 4 evaluation measures. The proposed low-complexity scheme, in contrast to other models in the literature, renders our model quite robust to cases of overfitting that typically accompany small datasets frequently encountered in medical classification challenges. Finally, the model can be easily re-trained in case additional volume images are included, as its simplistic architecture does not impose a significant computational burden.

eess.IV↗

An improved Epidemiological-Unscented Kalman Filter (Hybrid SEIHCRDV-UKF) model for the prediction of COVID-19. Application on real-time data

The prevalence of COVID-19 has been the most serious health challenge of the 21th century to date, concerning national health systems on a daily basis, since December 2019 when it appeared in Wuhan City. Nevertheless, most of the proposed mathematical methodologies aiming to describe the dynamics of an epidemic, rely on deterministic models that are not able to reflect the true nature of its spread. In this paper, we propose a SEIHCRDV model - an extension/improvement of the classic SIR compartmental model - which also takes into consideration the populations of exposed, hospitalized, admitted in intensive care units (ICU), deceased and vaccinated cases, in combination with an unscented Kalman filter (UKF), providing a dynamic estimation of the time dependent system's parameters. The stochastic approach is considered necessary, as both observations and system equations are characterized by uncertainties. Apparently, this new consideration is useful for examining various pandemics more effectively. The reliability of the model is examined on the daily recordings of COVID-19 in France, over a long period of 265 days. Two major waves of infection are observed, starting in January 2021, which signified the start of vaccinations in Europe providing quite encouraging predictive performance, based on the produced NRMSE values. Special emphasis is placed on proving the non-negativity of SEIHCRDV model, achieving a representative basic reproductive number R0 and demonstrating the existence and stability of disease equilibria according to the formula produced to estimate R0. The model outperforms in predictive ability not only deterministic approaches but also state-of-the-art stochastic models that employ Kalman filters.

q-bio.PE↗

Analysis of Digitalized ECG Signals Based on Artificial Intelligence and Spectral Analysis Methods Specialized in ARVC

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that appears between the second and forth decade of a patient's life, being responsible for 20% of sudden cardiac deaths before the age of 35. The effective and punctual diagnosis of this disease based on Electrocardiograms (ECGs) could have a vital role in reducing premature cardiovascular mortality. In our analysis, we firstly outline the digitalization process of paper - based ECG signals enhanced by a spatial filter aiming to eliminate dark regions in the dataset's images that do not correspond to ECG waveform, producing undesirable noise. Next, we propose the utilization of a low - complexity convolutional neural network for the detection of an arrhythmogenic heart disease, that has not been studied through the usage of deep learning methodology to date, achieving high classification accuracy, namely 99.98% training and 98.6% testing accuracy, on a disease the major identification criterion of which are infinitesimal millivolt variations in the ECG's morphology, in contrast with other arrhythmogenic abnormalities. Finally, by performing spectral analysis we investigate significant differentiations in the field of frequencies between normal ECGs and ECGs corresponding to patients suffering from ARVC. In 16 out of the 18 frequencies where we encounter statistically significant differentiations, the normal ECGs are characterized by greater normalized amplitudes compared to the abnormal ones. The overall research carried out in this article highlights the importance of integrating mathematical methods into the examination and effective diagnosis of various diseases, aiming to a substantial contribution to their successful treatment.

eess.SP↗