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Veronica Miro Pina

Publications and source records attributed to Veronica Miro Pina.

2 recordsLinked to original sources

Asymptotics of the frequency spectrum for general Dirichlet Xi-coalescents

In this work, we study general Dirichlet coalescents, which are a family of Xi-coalecents constructed from i.i.d mass partitions, and are an extension of the symmetric coalescent. This class of models is motivated by population models with recurrent demographic bottlenecks. We study the short time behavior of the multidimensional block counting process whose i-th component counts the number of blocks of size i. Compared to standard coalescent models (such as the class of Lambda-coalescents coming down from infinity), our process has no deterministic speed of coming down from infinity. In particular, we prove that, under appropriate re-scaling, it converges to a stochastic process which is the unique solution of a martingale problem. We show that the multivariate Lamperti transform of this limiting process is a Markov Additive Process (MAP). This allows us to provide some asymptotics for the n-Site Frequency Spectrum, which is a statistic widely used in population genetics. In particular, the rescaled number of mutations converges to the exponential functional of a subordinator.

math.PR↗

The Wright-Fisher model with efficiency

In populations competing for resources, it is natural to ask whether consuming fewer resources provides any selective advantage. To answer this question, we propose a Wright- Fisher model with two types of individuals: the inefficient individuals, those who need more resources to reproduce and can have a higher growth rate, and the efficient individuals. In this model, the total amount of resource N, is fixed, and the population size varies randomly depending on the number of efficient individuals. We show that, as N increases, the frequency process of efficient individuals converges to a diffusion which is a generalisation of the Wright- Fisher diffusion with selection. The genealogy of this model is given by a branching-coalescing process that we call the Ancestral Selection/Efficiency Graph, and that is an extension of the Ancestral Selection Graph (Krone and Neuhauser (1997a), Krone and Neuhauser (1997b)). The main contribution of this paper is that, in evolving populations, inefficiency can arise as a promoter of selective advantage and not necessarily as a trade-off.

math.PR↗