arXiv subjects

Victoria Yu. Samuta

Publications and source records attributed to Victoria Yu. Samuta.

2 recordsLinked to original sources

arXiv2019

Quantitative analysis of the dynamics of maternal gradients of the early Drosophila embryo

The predetermination, formation and maintenance of the primary morphogenetic gradient (bicoid gradient) of the early Drosophila embryo involves many interrelated processes. Here we focus on a system-biological analysis of the processes of redistribution of bicoid mRNA in an early embryo. The results of a quantitative analysis of experimental data, together with the results of their dynamic modeling, substantiate the role of active transport in the redistribution of bicoid mRNA.

q-bio.QM↗

arXiv2019

bcd mRNA active transport: 3D agent-based modeling

The article presents a 3D agent-based model to simulate the dynamics of redistribution of bicoid mRNA. The model is developed on the basis of the Skeledyne software [Odell and Foe, 2008]. The model reproduces active transport by molecular motors over an undirected network of short microtubules. The model is intended to simulate the data presented in [Spirov et al., 2009; Little et al., 2011; Fahmy et al., 2014; Ali-Murthy and Kornberg, 2016; Cai, Spirov, Akber et al., 2017].

q-bio.QM↗