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Viet Chi Tran

Publications and source records attributed to Viet Chi Tran.

At least 19 recordsLinked to original sources

Optimal score function estimation via derivatives constraints

We consider the problem of score function estimation via empirical risk minimization. We first start with the question of inferring the score function of a probability measure $μ$ with density on the flat torus from a sample of distribution $μ$. We show that constraining the hypothesis space to a Sobolev ball is sufficient to prevent overfitting and obtaining minimax estimation rates. We then consider the problem of score function estimation in the context of score-based generative modeling. Again, under a conjecture tying the score estimation rates to the quality of the output of a score-based generative model, we obtain minimax rates for such an approach using score function estimators obtained by constraining the hypothesis class to a Sobolev ball.

math.ST

From stochastic individual-based models to free-boundary Hamilton-Jacobi equations

We study a stochastic branching model for a population structured by a quantitative phenotypic trait and subject to births, deaths, and mutations. In a regime of large population and small mutations, and in logarithmic scales of size and time, we derive a certain class of free boundary Hamilton-Jacobi equations with state constraints from the stochastic individual-based system. This goes beyond the classical Hamilton-Jacobi equations obtained from deterministic models by taking into account the possible extinction of the system in certain regions of the trait space. The proof is obtained by combining methods for the analysis of Hamilton-Jacobi equations with probabilistic tools from the theory of large deviations and branching processes.

math.PR

Goodness-of-fit testing for the stationary density of a size-structured PDE

We consider two division models for structured cell populations, where cells can grow, age and divide. These models have been introduced in the literature under the denomination of `mitosis' and `adder' models. In the recent years, there has been an increasing interest in biology to understand whether the cells divide equally or not, as this can be related to important mechanisms in cellular aging or recovery. We are therefore interested in testing the null hypothesis $H_0$ where the division of a mother cell results into two daughters of equal size, against the alternative hypothesis $H_1$ where the division is asymmetric and ruled by a kernel that is absolutely continuous with respect to the Lebesgue measure. The sample consists of i.i.d. observations of cell sizes and ages drawn from the population, and the division is not directly observed. The hypotheses of the test are reformulated as hypotheses on the stationary size and age distributions of the models, which we assume are also the distributions of the observations. We propose a goodness-of-fit test that we study numerically on simulated data before applying it on real data.

stat.ME

Measure estimation on a manifold explored by a diffusion process

From the observation of a diffusion path $(X_t)_{t\in [0,T]}$ on a compact connected $d$-dimensional manifold $\mathcal{M}$ without boundary, we consider the problem of estimating the stationary measure $μ$ of the process. Wang and Zhu (2023) showed that for the Wasserstein metric $\mathcal{W}_2$ and for $d\geq 5$, the convergence rate of $T^{-1/(d-2)}$ is attained by the occupation measure of the path $(X_t)_{t\in [0,T]}$ when $(X_t)_{t\in [0,T]}$ is a Langevin diffusion. We extend their result in several directions. First, we show that the rate of convergence holds for a large class of diffusion paths, whose generators are uniformly elliptic. Second, the regularity of the density $p$ of the stationary measure $μ$ with respect to the volume measure of $\mathcal{M}$ can be leveraged to obtain faster estimators: when $p$ belongs to a Sobolev space of order $\ell\geq 2$, smoothing the occupation measure by convolution with a kernel yields an estimator whose rate of convergence is of order $T^{-(\ell+1)/(2\ell+d-2)}$. We further show that this rate is the minimax rate of estimation for this problem.

math.ST

Continuous limits of large plant-pollinator random networks and some applications

We study a stochastic individual-based model of interacting plant and pollinator species through a bipartite graph: each species is a node of the graph, an edge representing interactions between a pair of species. The dynamics of the system depends on the between- and within-species interactions: pollination by insects increases plant reproduction rate but has a cost which can increase plant death rate, depending on the densities of pollinators. Pollinators reproduction is increased by the resources harvested on plants. Each species is characterized by a trait corresponding to its degree of generalism. This trait determines the structure of the interaction graph and the quantities of resources exchanged between species. Our model includes in particular nested or modular networks. Deterministic approximations of the stochastic measure-valued process by systems of ordinary differential equations or integro-differential equations are established and studied, when the population is large or when the graph is dense and can be replaced with a graphon. The long-time behaviors of these limits are studied and central limit theorems are established to quantify the difference between the discrete stochastic individual-based model and the deterministic approximations. Finally, studying the continuous limits of the interaction network and the resulting PDEs, we show that nested plant-pollinator communities are expected to collapse towards a coexistence between a single pair of species of plants and pollinators.

math.PR

Individual based SIS models on (not so) dense large random networks

Starting from a stochastic individual-based description of an SIS epidemic spreading on a random network, we study the dynamics when the size $n$ of the network tends to infinity. We recover in the limit an infinite-dimensional integro-differential equation studied by Delmas, Dronnier and Zitt (2022) for an SIS epidemic propagating on a graphon. Our work covers the case of dense and sparse graphs, provided that the number of edges grows faster than $n$, but not the case of very sparse graphs with $O(n)$ edges. In order to establish our limit theorem, we have to deal with both the convergence of the random graphs to the graphon and the convergence of the stochastic process spreading on top of these random structures: in particular, we propose a coupling between the process of interest and an epidemic that spreads on the complete graph but with a modified infection rate. Keywords: Random graph, mathematical models of epidemics, measure-valued process, large network limit, limit theorem, graphon.

math.PR

Random walks on simplicial complexes

The notion of Laplacian of a graph can be generalized to simplicial complexes and hypergraphs, and contains information on the topology of these structures. Even for a graph, the consideration of associated simplicial complexes is interesting to understand its shape. Whereas the Laplacian of a graph has a simple probabilistic interpretation as the generator of a continuous time Markov chain on the graph, things are not so direct when considering simplicial complexes. We define here new Markov chains on simplicial complexes. For a given order~$k$, the state space is the set of $k$-cycles that are chains of $k$-simplexes with null boundary. This new framework is a natural generalization of the canonical Markov chains on graphs. We show that the generator of our Markov chain is the upper Laplacian defined in the context of algebraic topology for discrete structure. We establish several key properties of this new process: in particular, when the number of vertices is finite, the Markov chain is positive recurrent. This result is not trivial, since the cycles can loop over themselves an unbounded number of times. We study the diffusive limits when the simplicial complexes under scrutiny are a sequence of ever refining triangulations of the flat torus. Using the analogy between singular and Hodge homologies, we express this limit as valued in the set of currents. The proof of tightness and the identification of the limiting martingale problem make use of the flat norm and carefully controls of the error terms in the convergence of the generator. Uniqueness of the solution to the martingale problem is left open. An application to hole detection is carried.

math.PR

Thick trace at infinity for the Hyperbolic Radial Spanning Tree

Since the works of Howard and Newman (2001), it is known that in straight radial rooted trees, with probability 1, infinite paths all have an asymptotic direction and each asymptotic direction is reached by (at least) an infinite path. Moreover, there exists a set of 'exceptionnal' directions reached by (at least) two infinite paths which is random, dense and only countable in dimension 2. Howard and Newman's method says nothing about (random) directions reached by more than two infinite paths and, in particular, if such 'very exceptionnal' directions exist in dimension 2. In this paper, we prove that the answer is no for the hyperbolic Radial Spanning Tree (RST): in dimension 2, this tree does not contain 3 infinite paths with the same (random) asymptotic direction with probability one. Turned in another way, this means that there is no infinite but thin subtree in the hyperbolic RST, i.e. whose infinite paths would all have the same asymptotic direction. We actually prove a stronger result in dimension $d+1$, $d\geq 1$, stating that any infinite subtree of the hyperbolic RST a.s. generates a thick trace at infinity, i.e. the set of asymptotic directions reached by its infinite paths has a positive measure.

math.PR

Complex systems in Ecology: a guided tour with large Lotka-Volterra models and random matrices

Ecosystems represent archetypal complex dynamical systems, often modelled by coupled differential equations of the form $$ \frac{d x_i}{d t} = x_i φ_i(x_1,\cdots, x_N)\ , $$ where $N$ represents the number of species and $x_i$, the abundance of species $i$. Among these families of coupled diffential equations, Lotka-Volterra (LV) equations $$ \frac{d x_i}{d t} = x_i ( r_i - x_i +(Γ\mathbf{x})_i)\ , $$ play a privileged role, as the LV model represents an acceptable trade-off between complexity and tractability. Here, $r_i$ represents the intrinsic growth of species $i$ and $Γ$ stands for the interaction matrix: $Γ_{ij}$ represents the effect of species $j$ over species $i$. For large $N$, estimating matrix $Γ$ is often an overwhelming task and an alternative is to draw $Γ$ at random, parametrizing its statistical distribution by a limited number of model features. Dealing with large random matrices, we naturally rely on Random Matrix Theory (RMT). The aim of this review article is to present an overview of the work at the junction of theoretical ecology and large random matrix theory. It is intended to an interdisciplinary audience spanning theoretical ecology, complex systems, statistical physics and mathematical biology.

q-bio.PE

Hyperbolic Radial Spanning Tree

We define and analyze an extension to the $d$-dimensional hyperbolic space of the Radial Spanning Tree (RST) introduced by Baccelli and Bordenave in the two-dimensional Euclidean space (2007). In particular, we will focus on the description of the infinite branches of the tree. The properties of the two-dimensional Euclidean RST are extended to the hyperbolic case in every dimension: almost surely, every infinite branch admits an asymptotic direction and each asymptotic direction is reached by at least one infinite branch. Moreover, the branch converging to any deterministic asymptotic direction is unique almost surely. To obtain results for any dimension, a completely new approach is considered here. \tvc{Our strategy mainly involves the two following ingredients, that rely on the hyperbolic Directed Spanning Forest (DSF) introduced and studied in Flammant (2019).} First, the hyperbolic metric allows us to obtain fine control of the branches' fluctuations in the hyperbolic DSF without using planarity arguments. Then, we couple the hyperbolic RST with the hyperbolic DSF and conclude.

math.PR

Evolving genealogies for branching populations under selection and competition

For a continuous state branching process with two types of individuals which are subject to selection and density dependent competition, we characterize the joint evolution of population size, type configurations and genealogies as the unique strong solution of a system of SDE's. Our construction is achieved in the lookdown framework and provides a synthesis as well as a generalization of cases considered separately in two seminal papers by Donnelly and Kurtz (1999), namely fluctuating population sizes under neutrality, and selection with constant population size. As a conceptual core in our approach we introduce the selective lookdown space which is obtained from its neutral counterpart through a state-dependent thinning of ``potential'' selection/competition events whose rates interact with the evolution of the type densities. The updates of the genealogical distance matrix at the ``active'' selection/competition events are obtained through an appropriate sampling from the selective lookdown space. The solution of the above mentioned system of SDE's is then mapped into the joint evolution of population size and symmetrized type configurations and genealogies, i.e. marked distance matrix distributions. By means of Kurtz' Markov mapping theorem, we characterize the latter process as the unique solution of a martingale problem. For the sake of transparency we restrict the main part of our presentation to a prototypical example with two types, which contains the essential features. In the final section we outline an extension to processes with multiple types including mutation.

math.PR

Algebraic two-level measure trees

With the algebraic trees, Löhr and Winter (2021) introduced a generalization of the notion of graph-theoretic trees to account for potentially uncountable structures. The tree structure is given by the map which assigns to each triple of points their branch point. No edge length or distance is considered. One can equip a tree with a natural topology and a probability measure on the Borel-$σ$-field, defining in this way an algebraic measure tree. The main result of Löhr and Winter is to provide with the sample shape convergence a compact topology on the space of binary algebraic measure trees. This was proved by encoding the latter with triangulations of the circle. In the present paper, we extend this result to a two level setup. Motivated by the study of hierarchical systems with two levels in biology, such as host-parasite populations, we equip algebraic trees with a probability measure on the set of probability measures. To show the compactness of the space of binary algebraic two-level measure trees, we enrich the encoding of these trees by triangulations of the circle, by adding a two-level measure on the circle line. As an application, we define the two-level algebraic Kingman tree, that is the random algebraic two-level measure tree obtained from the nested Kingman coalescent.

math.PR

Filling the gap between individual-based evolutionary models and Hamilton-Jacobi equations

We consider a stochastic model for the evolution of a discrete population structured by a trait with values on a finite grid of the torus, and with mutation and selection. Traits are vertically inherited unless a mutation occurs, and influence the birth and death rates. We focus on a parameter scaling where population is large, individual mutations are small but not rare, and the grid mesh for the trait values is much smaller than the size of mutation steps. When considering the evolution of the population in a long time scale, the contribution of small sub-populations may strongly influence the dynamics. Our main result quantifies the asymptotic dynamics of sub-population sizes on a logarithmic scale. We establish that under the parameter scaling the logarithm of the stochastic population size process, conveniently normalized, converges to the unique viscosity solution of a Hamilton-Jacobi equation. Such Hamilton-Jacobi equations have already been derived from parabolic integro-differential equations and have been widely developed in the study of adaptation of quantitative traits. Our work provides a justification of this framework directly from a stochastic individual based model, leading to a better understanding of the results obtained within this approach. The proof makes use of almost sure maximum principles and careful controls of the martingale parts.

math.PR

Time reversal of spinal processes for linear and non-linear branching processes near stationarity

We consider a stochastic individual-based population model with competition, trait-structure affecting reproduction and survival, and changing environment. The changes of traits are described by jump processes, and the dynamics can be approximated in large population by a non-linear PDE with a non-local mutation operator. Using the fact that this PDE admits a non-trivial stationary solution, we can approximate the non-linear stochastic population process by a linear birth-death process where the interactions are frozen, as long as the population remains close to this equilibrium. This allows us to derive, when the population is large, the equation satisfied by the ancestral lineage of an individual uniformly sampled at a fixed time $T$, which is the path constituted of the traits of the ancestors of this individual in past times $t\leq T$. This process is a time inhomogeneous Markov process, but we show that the time reversal of this process possesses a very simple structure (e.g. time-homogeneous and independent of $T$). This extends recent results where the authors studied a similar model with a Laplacian operator but where the methods essentially relied on the Gaussian nature of the mutations.

math.PR

Estimation of dense stochastic block models visited by random walks

We are interested in recovering information on a stochastic block model from the subgraph discovered by an exploring random walk. Stochastic block models correspond to populations structured into a finite number of types, where two individuals are connected by an edge independently from the other pairs and with a probability depending on their types. We consider here the dense case where the random network can be approximated by a graphon. This problem is motivated from the study of chain-referral surveys where each interviewee provides information on her/his contacts in the social network. First, we write the likelihood of the subgraph discovered by the random walk: biases are appearing since hubs and majority types are more likely to be sampled. Even for the case where the types are observed, the maximum likelihood estimator is not explicit any more. When the types of the vertices is unobserved, we use an SAEM algorithm to maximize the likelihood. Second, we propose a different estimation strategy using new results by Athreya and Roellin. It consists in de-biasing the maximum likelihood estimator proposed in Daudin et al. and that ignores the biases.

math.ST

Dynamics of lineages in adaptation to a gradual environmental change

We investigate a simple quantitative genetics model subjet to a gradual environmental change from the viewpoint of the phylogenies of the living individuals. We aim to understand better how the past traits of their ancestors are shaped by the adaptation to the varying environment. The individuals are characterized by a one-dimensional trait. The dynamics -- births and deaths -- depend on a time-changing mortality rate that shifts the optimal trait to the right at constant speed. The population size is regulated by a nonlinear non-local logistic competition term. The macroscopic behaviour can be described by a PDE that admits a unique positive stationary solution. In the stationary regime, the population can persist, but with a lag in the trait distribution due to the environmental change. For the microscopic (individual-based) stochastic process, the evolution of the lineages can be traced back using the historical process, that is, a measure-valued process on the set of continuous real functions of time. Assuming stationarity of the trait distribution, we describe the limiting distribution, in large populations, of the path of an individual drawn at random at a given time $T$. Freezing the non-linearity due to competition allows the use of a many-to-one identity together with Feynman-Kac's formula. This path, in reversed time, remains close to a simple Ornstein-Uhlenbeck process. It shows how the lagged bulk of the present population stems from ancestors once optimal in trait but still in the tail of the trait distribution in which they lived.

math.PR

Respondent Driven Sampling on sparse Erdös-Rényi graphs

We study the exploration of an Erdös-Rényi random graph by a respondent-driven sampling method, where discovered vertices reveal their neighbours. Some of them receive coupons to reveal in their turn their own neighbourhood. This leads to the study of a Markov chain on the random graph that we study. For sparse Erdös-Rényi graphs of large sizes, this process correctly renormalized converges to the solution of a deterministic curve, solution of a system of ODEs absorbed on the abscissa axis. The associated fluctuation process is also studied, providing a functional central limit theorem, with a Gaussian limiting process. Simulations and numerical computation illustrate the study.

math.PR

Nonparametric estimation of the fragmentation kernel based on a PDE stationary distribution approximation

We consider a stochastic individual-based model in continuous time to describe a size-structured population for cell divisions. This model is motivated by the detection of cellular aging in biology. We address here the problem of nonparametric estimation of the kernel ruling the divisions based on the eigenvalue problem related to the asymptotic behavior in large population. This inverse problem involves a multiplicative deconvolution operator. Using Fourier technics we derive a nonparametric estimator whose consistency is studied. The main difficulty comes from the non-standard equations connecting the Fourier transforms of the kernel and the parameters of the model. A numerical study is carried out and we pay special attention to the derivation of bandwidths by using resampling.

math.ST