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Viktor Matyas

Publications and source records attributed to Viktor Matyas.

2 recordsLinked to original sources

OpenTME: An Open Dataset of AI-powered H&E Tumor Microenvironment Profiles from TCGA

The tumor microenvironment (TME) plays a central role in cancer progression, treatment response, and patient outcomes, yet large-scale, consistent, and quantitative TME characterization from routine hematoxylin and eosin (H&E)-stained histopathology remains scarce. We introduce OpenTME, an open-access dataset of pre-computed TME profiles derived from 3,634 H&E-stained whole-slide images across five cancer types (bladder, breast, colorectal, liver, and lung cancer) from The Cancer Genome Atlas (TCGA). All outputs were generated using Atlas H&E-TME, an AI-powered application built on the Atlas family of pathology foundation models, which performs tissue quality control, tissue segmentation, cell detection and classification, and spatial neighborhood analysis, yielding over 4,500 quantitative readouts per slide at cell-level resolution. OpenTME is available for non-commercial academic research on Hugging Face. We will continue to expand OpenTME over time and anticipate it will serve as a resource for biomarker discovery, spatial biology research, and the development of computational methods for TME analysis.

cs.CV

Banks-Zaks Stabilisation of Non-SUSY Strings

It appears to be difficult within string theory to obtain genuine scale separation between spacetime and the internal sector. In this paper, we propose a novel mechanism for scale-separated vacua which hinges on stringy effects that are invisible at the level of effective field theory. We show that (meta)stable vacua can form if a super no-scale one-loop potential combines with generic two-loop contributions to the vacuum energy, in a manner analogous to Banks-Zaks fixed points. Weak string coupling and scale separation arise from the accidental smallness of the one-loop term, which receives contributions only from massive states, relative to the two-loop term. We provide a proof of concept of this mechanism in explicit non-supersymmetric heterotic toroidal orbifolds by balancing the complete one-loop contribution against the estimated two-loop term and numerically minimizing the resulting effective potential in a restricted sector of moduli space. We note that this mechanism is generically possible within any fundamental theory that has a one-loop energy that gets contributions only from massive modes.

hep-th