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Vivek Singh

Publications and source records attributed to Vivek Singh.

At least 19 recordsLinked to original sources

A semiclassical Hilbert space for random matrix theory

We study the one-sided time evolution of thermofield double (TFD) states in random matrix theory, where the Hamiltonian is taken to be a $D\times D$ random matrix drawn from a unitarily invariant emsemble of Hermitian matrices. We argue that the Krylov basis with the maximally entangled state taken as the initial vector gives a semiclassical Hilbert space description of these TFD states in random matrix theory at any $O(1)$ temperature and time in the $D\to \infty$ limit, very analogous to the ``chord Hilbert space'' construction in the double-scaled SYK (DSSYK) model. We study this semiclassical description in detail for ensembles where the spectral density in the $D\to \infty$ limit is even, compactly supported on an interval and has square root edges. With a few more conditions on the analytic structure of the spectral density, we observe that the semiclassical Hamiltonian has the same asymptotic behavior at large Krylov depth as that of DSSYK, with the corresponding parameter $\mathfrak{q}=e^{-\lambda}$ being related to the location of the nearest zero of the spectral density away from the spectral cut. Furthermore, in a large class of models corresponding to ultraviolet deformations of the DSSYK spectral density, i.e., where the spectrum in the UV is modified while leaving the near-edge behavior unchanged, we show that the semiclassical effective Hamiltonian in the Krylov basis reduces to the Liouville Hamiltonian of JT gravity in a low-energy, continuum limit. This suggests that our semiclassical Hilbert space should be interpreted as the bulk Hilbert space of a dual gravity description.

hep-th

Multiplicative Errors-in-Variables Models for Hyperspectral Unmixing

Estimating endmember spectra and their corresponding abundances from hyperspectral images is a fundamental inverse problem in remote sensing. The standard linear mixing model relies on additive homoscedastic errors, which misspecifies the mean-variance relationship inherent to optical measurements for which the noise intensity might be proportional to the signal magnitude. This leads to confidence intervals with poor coverage. To address these limitations, we propose a hierarchical Bayesian multiplicative Errors-in-Variables (EIV) model. Motivated by the physics of light propagation, our formulation captures signal-dependent noise through a multivariate log-normal specification that naturally accommodates dependence across spectral bands. The EIV framework treats endmember signatures as random and allows for class-specific variance scaling, yielding a flexible and physically grounded data-generating process. We establish that the MLE of the abundance vector under the multiplicative model has a constant asymptotic multivariate coefficient of variation, implying that well-calibrated confidence intervals should scale proportionally with signal magnitude. The additive model, by contrast, produces intervals of constant width regardless of signal magnitude, leading to overcoverage at low abundance and undercoverage at high abundance when the true noise is multiplicative. Practical implementation and inference for the full hierarchical model is obtained from posterior distributions over the model parameters. Experiments on several real and simulated datasets demonstrate that confidence intervals derived from the proposed model achieve improved coverage across abundance levels compared to those from a standard additive model, with widths that scale proportionally with signal magnitude, while achieving comparable or superior signal reconstruction error.

stat.ME

Wigner negativity in Krylov space and emergent semiclassicality

We propose that the Krylov basis gives a semiclassical representation of dynamics in general large-$N$, complex, many-body systems. As a probe of this semiclassicality, we study the growth of Wigner negativity -- a measure of the complexity of classical simulation -- under time evolution in Krylov space in several solvable models. We begin with 2d CFTs, initially in either the vacuum or the thermofield double state on a line excited by a primary operator. In both cases, Wigner negativity remains an $O(1)$ constant and does not grow at late times, indicating approximately classical dynamics in the Krylov basis. We then study random matrix theory with the maximally entangled state between two copies as the initial state. For general one-cut matrix models, we argue that Wigner negativity in the Krylov basis grows as $t^{1/2}$ at large $O(1)$ times but does not scale with the Hilbert space dimension, thus indicating semiclassical dynamics in Krylov space. Finally, in the double-scaled SYK model, we find an approximately classical phase (constant negativity) at early times and a semiclassical phase ($t^{1/2}$ growth) at late times. In all these examples, Wigner negativity either remains constant or grows slowly, demonstrating emergent semiclassicality of dynamics in Krylov space.

hep-th

An Empirical Study of Automating Agent Evaluation

Agent evaluation requires assessing complex multi-step behaviors involving tool use and intermediate reasoning, making it costly and expertise-intensive. A natural question arises: can frontier coding assistants reliably automate this evaluation process? Our study shows that simply prompting coding assistants is insufficient for this task. Without domain-specific evaluation knowledge, frontier coding assistants achieve only a 30% execution success rate and produce over-engineered evaluations averaging 12+ metrics per agent, indicating that strong coding ability does not automatically translate to reliable agent evaluation. We introduce EvalAgent, an AI assistant that automates the end-to-end agent evaluation pipeline. EvalAgent encodes evaluation domain expertise as evaluation skills (procedural instructions, reusable code and templates, and dynamically retrieved API documentation) that compose into a trace-based pipeline producing complete evaluation artifacts including metrics, executable code, and reports. To systematically assess generated evaluations, we introduce a meta-evaluation framework alongside AgentEvalBench, a benchmark comprising 20 agents, each paired with evaluation requirements and test scenarios. We further propose the Eval@1 metric to measure whether generated evaluation code both executes and yields meaningful results on the first run. Our experiments show that EvalAgent produces focused evaluations, improving Eval@1 from 17.5% to 65%, and achieving 79.5% human expert preference over baseline approaches. Further ablation studies show that evaluation skills are critical for handling complex evaluation: removing them causes Eval@1 to drop significantly from 65% to 30%.

cs.CL

A chemical language model for reticular materials design

Reticular chemistry has enabled the synthesis of tens of thousands of metal-organic frameworks (MOFs), yet the discovery of new materials still relies largely on intuition-driven linker design and iterative experimentation. As a result, researchers explore only a small fraction of the vast chemical space accessible to reticular materials, limiting the systematic discovery of frameworks with targeted properties. Here, we introduce Nexerra-R1, a building-block chemical language model that enables inverse design in reticular chemistry through the targeted generation of organic linkers. Rather than generating complete frameworks directly, Nexerra-R1 operates at the level of molecular building blocks, preserving the modular logic that underpins reticular synthesis. The model supports both unconstrained generation of low-connectivity linkers and scaffold-constrained design of symmetric multidentate motifs compatible with predefined nodes and topologies. We further combine linker generation with flow-guided distributional targeting to steer the generative process toward application-relevant objectives while maintaining chemical validity and assembly feasibility. The generated linkers are subsequently assembled into three-dimensional frameworks and are structurally optimized to produce candidate materials compatible with experimental synthesis. Using Nexerra-R1, we validate this strategy by rediscovering known MOFs and by proposing the experimental synthesis of a previously unreported framework, CU-525, generated entirely in silico. Together, these results establish a general inverse-design paradigm for reticular materials in which controllable chemical language modelling enables the direct translation from computational design to synthesizable frameworks.

cond-mat.mtrl-sci

Transforming Computational Lithography with AC and AI -- Faster, More Accurate, and Energy-efficient

From climate science to drug discovery, scientific computing demands have surged dramatically in recent years -- driven by larger datasets, more sophisticated models, and higher simulation fidelity. This growth rate far outpaces transistor scaling, leading to unsustainably rising costs, energy consumption, and emissions. Semiconductor manufacturing is no exception. Computational lithography -- involving transferring circuitry to silicon in diffraction-limited conditions -- is the largest workload in semiconductor manufacturing. It has also grown exceptionally complex as miniaturization has advanced in the angstrom-era, requiring more accurate modeling, intricate corrections, and broader solution-space exploration. Accelerated computing (AC) offers a solution by dramatically freeing up the compute and power envelope. AI augments these gains by serving as high-fidelity surrogates for compute-intensive steps. Together, they present a sustainable, next-generation computing platform for scientific workloads. This new paradigm needs a fundamental redesign of the software stack. For computational lithography, NVIDIA cuLitho reinvents the core primitives -- diffractive optics, computational geometry, multi-variant optimization, data processing -- to achieve a transformative 57X end-to-end acceleration. Beyond dramatically faster cycles, this expanded compute envelope enables more rigorous solutions, including curvilinear masks, high-numerical aperture extreme ultraviolet (high-NA EUV) lithography, and subatomic modeling. We reinvest a small fraction of the freed-up compute to include through-focus correction for better process resilience. Silicon experiments at IMEC show significant benefits compared to conventional methods -- 35% better process window and 19% better edge placement error. This is the first quantified chip-scale demonstration of the lithography benefits of AC and AI in silicon.

eess.SP

$S$-units and period length of continued fractions of linear recursions

Let $(A_n)_{n\in \mathbb{Z}}$ be a linear recurrence sequence with values in a real quadratic field. In this paper, we study the question whether the period length of the continued fraction of $A_n$ is bounded as $n$ varies. The case where $(A_n)_n$ is a linear recurrence of degree $1$ has previously been solved by Corvaja and Zannier. Their result settled a problem posed by Mend\`es France about the length of the periods of the continued fractions for $\alpha^n$.

math.NT

Readout noise of digital frequency multiplexed TES detectors for CUPID

Superconducting transition-edge sensor (TES) detectors have been the standard in Cosmic Microwave Background experiments for almost two decades and are now being adapted for use in nuclear physics, such as neutrinoless double beta decay searches. In this paper we focus on a new high-bandwidth frequency multiplexed TES readout system developed for CUPID, a neutrinoless double beta decay experiment that will replace CUORE. In order to achieve the high energy resolution requirements for CUPID, the readout noise of the system must be kept to a minimum. Low TES operating resistance and long wiring between the readout SQUID and the warm electronics are needed for CUPID, prompting a careful consideration of the design parameters of this application of frequency multiplexing. In this work, we characterize the readout noise of the newly designed frequency multiplexed TES readout system for CUPID and construct a noise model to understand it. We find that current sharing between the SQUID coil impedance and other branches of the circuit, as well as the long output wiring, worsen the readout noise of the system. To meet noise requirements, a SQUID with a low input inductance, high transimpedance and/or low dynamic impedance is needed, and the wiring capacitance should be kept as small as possible. Alternatively, the option of adding a cryogenic low-noise amplifier at the output of the SQUID should be explored.

physics.ins-det

AURA-CVC: Autonomous Ultrasound-guided Robotic Assistance for Central Venous Catheterization

Purpose: Central venous catheterization (CVC) is a critical medical procedure for vascular access, hemodynamic monitoring, and life-saving interventions. Its success remains challenging due to the need for continuous ultrasound-guided visualization of a target vessel and approaching needle, which is further complicated by anatomical variability and operator dependency. Errors in needle placement can lead to life-threatening complications. While robotic systems offer a potential solution, achieving full autonomy remains challenging. In this work, we propose an end-to-end robotic-ultrasound-guided CVC pipeline, from scan initialization to needle insertion. Methods: We introduce a deep-learning model to identify clinically relevant anatomical landmarks from a depth image of the patient's neck, obtained using RGB-D camera, to autonomously define the scanning region and paths. Then, a robot motion planning framework is proposed to scan, segment, reconstruct, and localize vessels (veins and arteries), followed by the identification of the optimal insertion zone. Finally, a needle guidance module plans the insertion under ultrasound guidance with operator's feedback. This pipeline was validated on a high-fidelity commercial phantom across 10 simulated clinical scenarios. Results: The proposed pipeline achieved 10 out of 10 successful needle placements on the first attempt. Vessels were reconstructed with a mean error of 2.15 \textit{mm}, and autonomous needle insertion was performed with an error less than or close to 1 \textit{mm}. Conclusion: To our knowledge, this is the first robotic CVC system demonstrated on a high-fidelity phantom with integrated planning, scanning, and insertion. Experimental results show its potential for clinical translation.

cs.RO

Multi-Agent Reinforcement Learning with Long-Term Performance Objectives for Service Workforce Optimization

Workforce optimization plays a crucial role in efficient organizational operations where decision-making may span several different administrative and time scales. For instance, dispatching personnel to immediate service requests while managing talent acquisition with various expertise sets up a highly dynamic optimization problem. Existing work focuses on specific sub-problems such as resource allocation and facility location, which are solved with heuristics like local-search and, more recently, deep reinforcement learning. However, these may not accurately represent real-world scenarios where such sub-problems are not fully independent. Our aim is to fill this gap by creating a simulator that models a unified workforce optimization problem. Specifically, we designed a modular simulator to support the development of reinforcement learning methods for integrated workforce optimization problems. We focus on three interdependent aspects: personnel dispatch, workforce management, and personnel positioning. The simulator provides configurable parameterizations to help explore dynamic scenarios with varying levels of stochasticity and non-stationarity. To facilitate benchmarking and ablation studies, we also include heuristic and RL baselines for the above mentioned aspects.

cs.AI

Deep learning-based identification of patients at increased risk of cancer using routine laboratory markers

Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to determine the screening method and frequency, primarily to optimize resource allocation by targeting screening towards individuals who draw most benefit. For most screening programs, age and clinical risk factors such as family history are part of the initial risk stratification algorithm. In this paper, we focus on developing a blood marker-based risk stratification approach, which could be used to identify patients with elevated cancer risk to be encouraged for taking a diagnostic test or participate in a screening program. We demonstrate that the combination of simple, widely available blood tests, such as complete blood count and complete metabolic panel, could potentially be used to identify patients at risk for colorectal, liver, and lung cancers with areas under the ROC curve of 0.76, 0.85, 0.78, respectively. Furthermore, we hypothesize that such an approach could not only be used as pre-screening risk assessment for individuals but also as population health management tool, for example to better interrogate the cancer risk in certain sub-populations.

cs.LG

Collaborative Human-AI Risk Annotation: Co-Annotating Online Incivility with CHAIRA

Collaborative human-AI annotation is a promising approach for various tasks with large-scale and complex data. Tools and methods to support effective human-AI collaboration for data annotation are an important direction for research. In this paper, we present CHAIRA: a Collaborative Human-AI Risk Annotation tool that enables human and AI agents to collaboratively annotate online incivility. We leveraged Large Language Models (LLMs) to facilitate the interaction between human and AI annotators and examine four different prompting strategies. The developed CHAIRA system combines multiple prompting approaches with human-AI collaboration for online incivility data annotation. We evaluated CHAIRA on 457 user comments with ground truth labels based on the inter-rater agreement between human and AI coders. We found that the most collaborative prompt supported a high level of agreement between a human agent and AI, comparable to that of two human coders. While the AI missed some implicit incivility that human coders easily identified, it also spotted politically nuanced incivility that human coders overlooked. Our study reveals the benefits and challenges of using AI agents for incivility annotation and provides design implications and best practices for human-AI collaboration in subjective data annotation.

cs.HC

Current Trends and Future Directions for Sexual Health Conversational Agents (CAs) for Youth: A Scoping Review

Conversational Agents (CAs, chatbots) are systems with the ability to interact with users using natural human dialogue. While much of the research on CAs for sexual health has focused on adult populations, the insights from such research may not apply to CAs for youth. The study aimed to comprehensively evaluate the state-of-the-art research on sexual health CAs for youth. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we synthesized peer-reviewed studies specific to sexual health CAs designed for youth over the past 14 years. We found that most sexual health CAs were designed to adopt the persona of health professionals to provide general sexual and reproductive health information for youth. Text was the primary communication mode in all sexual health CAs, with half supporting multimedia output. Many sexual health CAs employed rule-based techniques to deliver pre-written expert knowledge on sexual health; yet most sexual health CAs did not have the safety features in place. While youth appreciated accessibility to non-judgmental and confidential conversations about sexual health topics, they perceived current sexual health CAs provided limited sexual health information that is not inclusive of sexual and/or gender minorities. Our review brings to light sexual health CAs needing further development and evaluation and we identify multiple important areas for future work. While the new trend of large language models (LLMs) based CAs can make such technologies more feasible, the privacy and safety of the systems should be prioritized. Finally, best practices for risk mitigation and ethical development of sexual health CAs with and for youth are needed.

cs.HC

Measuring Electron Energy in Muon-to-Electron Conversion using Holographic Synchrotron Radiation Emission Spectroscopy

The coherent conversion of a muon to an electron in a nuclear field has been one of the most powerful methods for searching for charged lepton flavor violation. Recent advancements have significantly enhanced the sensitivity of $\mu \rightarrow e$ searches, primarily driven by advancements in muon beamline design and low-mass tracking detectors, which afford exceptional momentum resolution. Nevertheless, the performance of these detectors is inherently limited by electron scattering and energy loss within detector materials. We propose a {\em holographic} track reconstruction method that leverages synchrotron radiation emitted by electrons to overcome these inevitable limitations. Similar to cyclotron radiation emission spectroscopy, which has demonstrated outstanding energy resolutions for low-energy electrons, our technique relies on a precision measurement of cyclotron frequency, but in a regime where photons are emitted stochastically and are projected onto a 2-dimensional inner surface of a solenoidal magnet. We outline the concept of such a massless holographic tracker and the feasibility of employing this innovative detection strategy for $\mu \rightarrow e$ conversion. We also address pertinent limitations and challenges inherent to the method.

physics.ins-det

Goal-conditioned reinforcement learning for ultrasound navigation guidance

Transesophageal echocardiography (TEE) plays a pivotal role in cardiology for diagnostic and interventional procedures. However, using it effectively requires extensive training due to the intricate nature of image acquisition and interpretation. To enhance the efficiency of novice sonographers and reduce variability in scan acquisitions, we propose a novel ultrasound (US) navigation assistance method based on contrastive learning as goal-conditioned reinforcement learning (GCRL). We augment the previous framework using a novel contrastive patient batching method (CPB) and a data-augmented contrastive loss, both of which we demonstrate are essential to ensure generalization to anatomical variations across patients. The proposed framework enables navigation to both standard diagnostic as well as intricate interventional views with a single model. Our method was developed with a large dataset of 789 patients and obtained an average error of 6.56 mm in position and 9.36 degrees in angle on a testing dataset of 140 patients, which is competitive or superior to models trained on individual views. Furthermore, we quantitatively validate our method's ability to navigate to interventional views such as the Left Atrial Appendage (LAA) view used in LAA closure. Our approach holds promise in providing valuable guidance during transesophageal ultrasound examinations, contributing to the advancement of skill acquisition for cardiac ultrasound practitioners.

cs.CV

The impact of generative artificial intelligence on socioeconomic inequalities and policy making

Generative artificial intelligence has the potential to both exacerbate and ameliorate existing socioeconomic inequalities. In this article, we provide a state-of-the-art interdisciplinary overview of the potential impacts of generative AI on (mis)information and three information-intensive domains: work, education, and healthcare. Our goal is to highlight how generative AI could worsen existing inequalities while illuminating how AI may help mitigate pervasive social problems. In the information domain, generative AI can democratize content creation and access, but may dramatically expand the production and proliferation of misinformation. In the workplace, it can boost productivity and create new jobs, but the benefits will likely be distributed unevenly. In education, it offers personalized learning, but may widen the digital divide. In healthcare, it might improve diagnostics and accessibility, but could deepen pre-existing inequalities. In each section we cover a specific topic, evaluate existing research, identify critical gaps, and recommend research directions, including explicit trade-offs that complicate the derivation of a priori hypotheses. We conclude with a section highlighting the role of policymaking to maximize generative AI's potential to reduce inequalities while mitigating its harmful effects. We discuss strengths and weaknesses of existing policy frameworks in the European Union, the United States, and the United Kingdom, observing that each fails to fully confront the socioeconomic challenges we have identified. We propose several concrete policies that could promote shared prosperity through the advancement of generative AI. This article emphasizes the need for interdisciplinary collaborations to understand and address the complex challenges of generative AI.

cs.CY

Leveraging Large Language Models (LLMs) to Support Collaborative Human-AI Online Risk Data Annotation

In this position paper, we discuss the potential for leveraging LLMs as interactive research tools to facilitate collaboration between human coders and AI to effectively annotate online risk data at scale. Collaborative human-AI labeling is a promising approach to annotating large-scale and complex data for various tasks. Yet, tools and methods to support effective human-AI collaboration for data annotation are under-studied. This gap is pertinent because co-labeling tasks need to support a two-way interactive discussion that can add nuance and context, particularly in the context of online risk, which is highly subjective and contextualized. Therefore, we provide some of the early benefits and challenges of using LLMs-based tools for risk annotation and suggest future directions for the HCI research community to leverage LLMs as research tools to facilitate human-AI collaboration in contextualized online data annotation. Our research interests align very well with the purposes of the LLMs as Research Tools workshop to identify ongoing applications and challenges of using LLMs to work with data in HCI research. We anticipate learning valuable insights from organizers and participants into how LLMs can help reshape the HCI community's methods for working with data.

cs.HC

Toward Safe Evolution of Artificial Intelligence (AI) based Conversational Agents to Support Adolescent Mental and Sexual Health Knowledge Discovery

Following the recent release of various Artificial Intelligence (AI) based Conversation Agents (CAs), adolescents are increasingly using CAs for interactive knowledge discovery on sensitive topics, including mental and sexual health topics. Exploring such sensitive topics through online search has been an essential part of adolescent development, and CAs can support their knowledge discovery on such topics through human-like dialogues. Yet, unintended risks have been documented with adolescents' interactions with AI-based CAs, such as being exposed to inappropriate content, false information, and/or being given advice that is detrimental to their mental and physical well-being (e.g., to self-harm). In this position paper, we discuss the current landscape and opportunities for CAs to support adolescents' mental and sexual health knowledge discovery. We also discuss some of the challenges related to ensuring the safety of adolescents when interacting with CAs regarding sexual and mental health topics. We call for a discourse on how to set guardrails for the safe evolution of AI-based CAs for adolescents.

cs.HC