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Volodymyr Kindratenko

Publications and source records attributed to Volodymyr Kindratenko.

At least 19 recordsLinked to original sources

Seamless Whole Slide Label-Free Virtual Staining

Label-free virtual staining offers a compelling, non-destructive alternative to standard histopathology; however, its clinical adoption is hindered by the computational bottlenecks inherent to processing gigapixel Whole Slide Images (WSIs). Current deep learning approaches require patch-based inference to avoid memory constraints, which disrupts global tissue continuity and introduces tiling artifacts--displaying visible seams and color shifts. To address this, we introduce the Consistency Memory Bank (COMB), a novel label-free virtual staining framework that enforces spatial and channel consistency across tiles without memory bottlenecks. COMB decouples context storage from computation, utilizing a dynamic retrieval mechanism to fetch feature representations from adjacent tiles. This enables a retrieval-based context integration strategy that adopts local padding to resolve spatial discontinuities and neighbor-aware channel attention to stabilize statistical drift. Further optimized with a sliding window schedule to ensure minimal memory overhead, our method demonstrates superior performance over state-of-the-art baselines, achieving significant improvements in both perceptual fidelity and tiling consistency, while suggesting its downstream utility in tumor segmentation. Code is available at https://github.com/dou0000/COMB.

eess.IV

Diamond Agent: Agentic Control of Federated HPC Resources as a Service

Efficiently aggregating and orchestrating computing power across heterogeneous clusters for HPC workflows faces four practical challenges: preserving workflow context across independently administered clusters, moving large datasets between sites, reasoning about site-specific environments and scheduler policies, and exploiting live queue and resource states for efficient task scheduling. To this end, we design Diamond Agent, an agentic system that enables intelligent execution of HPC workflows across heterogeneous clusters with typed skills as the interface. Diamond Agent provides an agent-facing workspace and skills that unify cross-site resource discovery, resource specification, data movement, task execution, and result retrieval. A centralized Diamond Agent instance can operate multiple supercomputers without being deployed separately on each login node. Diamond Agent translates high-level agent actions into valid site-specific executions, moves data through Globus Transfer, and uses live system capability and queue information to select feasible placements. Its event-driven continuation mechanism decouples agent actions from long-running batch jobs: persistent services monitor remote execution and resume the agent only when a result or decision-relevant event is available. We experiment with 27 hours of telemetry and 19 matched multi-site submission rounds comprising 83 jobs across four production supercomputers. Compared with a fixed-site baseline, Diamond Agent reduces the median additional completion time relative to the fastest observed placement from 42 seconds to 4 seconds, a 10.5x reduction.

cs.DC

CTA-Pipelining: A Latency-Oriented Spatial Scaling Method for Multi-GPU Systems

The evolution of compute infrastructure has transformed multi-GPU systems into tightly integrated shared-memory structures. However, current software still mostly treats these coherent interconnects simply as high-speed networks. Simultaneously, the demand for serving Large Language Models under latency constraints has shifted GPU workload optimization from being throughput-driven to latency-bound, necessitating latency-oriented scaling methods beyond Tensor Parallelism (TP). Thus, we introduce CTA-pipelining, an execution paradigm designed to exploit shared-memory multi-GPU systems. As a latency-oriented spatial scaling technique, CTA-pipelining leverages dependencies at the Cooperative Thread Array level, enabling concurrent execution of dependent kernels across GPUs. We demonstrate its capability using CUTLASS, cuBLAS, and NCCL libraries on 8-GPU H200 and B200 systems. Results show on 2-layer GEMM, representing the MLP operation, CTA-pipelining reduces latency by up to 31.8% compared to micro-batching, and 29.6% compared to TP. It can also be combined with TP as an orthogonal scaling dimension to further push the latency boundary.

cs.DC

Anatomy of a failure: When, how, and why deep vision fails in scientific domains

Mirroring its ubiquity in popular media and all human activities, the use of deep learning (DL) is rapidly growing in scientific imaging modalities. However, unlike everyday RGB pictures, pixels encode precise physicochemical properties in scientific imaging across potentially thousands of channels. While DL is well validated on human-centric RGB perceptual tasks, its effectiveness for scientific imaging remains uncertain. Here, we show that the naive application of DL frameworks to scientific images can lead to critical failures. We evaluate the use of DL for pathology, comparing RGB images of stained tissue with the quantitative and information-rich biochemical signatures of infrared (IR) imaging. Despite this informational advantage, DL models trained on IR data paradoxically underperform. We investigate this discrepancy to find that IR data priors interact poorly with the simplicity bias of DL, causing models to collapse to one-dimensional predictions. This constitutes a catastrophic DL failure because the model's representational capacity remains largely unused, while furthermore raising AI safety concerns and undermining the advantages of such scientific modalities. Notably, this problem persists even with state-of-the-art DL robustification strategies, which are primarily designed and validated for RGB imagery and thus inherit the same prior-bias mismatch. This work establishes a framework for understanding the limitations of generic DL in science and advocates for the study of modality-specific failure modes to guide the development of specialized, safe AI algorithms.

cs.CV

SPARCLE: SPeaker-aware Aligned Representations via Contrastive Language Embeddings

Recent advances in speech synthesis have shifted from phoneme representations to direct grapheme modeling. While phonemes address the one-to-many mapping between text and acoustics, they rely on grapheme-to-phoneme (G2P) systems that fail to capture speaker-specific acoustic variation. Prior work demonstrates that grapheme-based models outperform phoneme-based systems at scale, but not in low-resource settings. In this paper, we propose SPARCLE, a speaker-aware grapheme representation model that enriches characters with their precise acoustic realizations. SPARCLE is trained with a contrastive objective to align graphemes with corresponding Wav2Vec2 acoustic representations while conditioned on speaker identity. The resulting model serves as a replacement to G2P systems for downstream text-to-speech (TTS) tasks. We demonstrate that SPARCLE improves generation quality, reducing word error rates by half in extreme low-resource settings compared to standard grapheme-based models.

cs.CL

Few-Shot Synthetic Accented Speech for ASR Fine-Tuning: What Helps and When?

Synthetic accented speech is a promising way to improve automatic speech recognition (ASR) when real accented recordings are scarce. We ask what makes such data useful for ASR fine-tuning: target-accent phoneme edits that expose the recognizer to accent-specific pronunciations, or random phoneme perturbations that act as augmentation in phoneme space. In a few-shot TTS pipeline, we compare LLM-generated accent edits with matched-rate random substitutions and oracle controls using ground-truth accented phonemes and prosody. Random substitutions recover much of the ASR gain: LLM target-accent edits improve over random by only a small margin, ground-truth phonemes stay close to the random baseline and nearly converge with it as the synthetic ASR fine-tuning set grows larger, and adding ground-truth prosody yields only a modest further gain. Mixing synthetic with real accented speech also stabilizes low-resource fine-tuning, but a fixed synthetic budget can later dilute the information in real data, showing that the real--synthetic ratio matters.

cs.SD

Accent Conversion: A Problem-Driven Survey of Sociolinguistic and Technical Constraints

Accent conversion has rapidly progressed alongside growing interest in improving global cross-cultural communication. This survey presents an overview of the evolution of accent conversion methodologies, analyzing how the field has developed in response to fundamental challenges related to data alignment, representation disentanglement, and resource scarcity. We trace the progression from early rule-based digital signal processing approaches such as spectral manipulation and formant-based analysis to modern neural architectures capable of flexible and reference-free accent transformation. In addition, the survey situates accent conversion within its linguistic foundations and examines how different application requirements impose varying constraints on the balance between accent modification and speaker identity preservation. Finally, it reviews commonly used speech datasets and evaluation methodologies, identifies persistent challenges, and outlines directions for future research aimed at achieving more controllable and perceptually consistent accent conversion.

cs.SD

FAC-FACodec: Controllable Zero-Shot Foreign Accent Conversion with Factorized Speech Codec

Previous accent conversion (AC) methods, including foreign accent conversion (FAC), lack explicit control over the degree of modification. Because accent modification can alter the perceived speaker identity, balancing conversion strength and identity preservation is crucial. We present an AC framework that provides an explicit, user-controllable parameter to adjust the strength of pronunciation-level accent modification. Results show performance comparable to recent AC systems, stronger preservation of speaker identity, and unique support for controllable accent conversion.

cs.SD

Hierarchical Diffusion Framework for Pseudo-Healthy Brain MRI Inpainting with Enhanced 3D Consistency

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices produces discontinuities in the volume. Fully 3D models alleviate this issue, but their high model capacity demands extensive training data for reliable, high-fidelity synthesis -- often impractical in medical settings. We address these limitations with a hierarchical diffusion framework by replacing direct 3D modeling with two perpendicular coarse-to-fine 2D stages. An axial diffusion model first yields a coarse, globally consistent inpainting; a coronal diffusion model then refines anatomical details. By combining perpendicular spatial views with adaptive resampling, our method balances data efficiency and volumetric consistency. Our experiments show our approach outperforms state-of-the-art baselines in both realism and volumetric consistency, making it a promising solution for pseudo-healthy image inpainting. Code is available at https://github.com/dou0000/3dMRI-Consistent-Inpaint.

eess.IV

FedCostAware: Enabling Cost-Aware Federated Learning on the Cloud

Federated learning (FL) is a distributed machine learning (ML) approach that allows multiple clients to collaboratively train ML models without exchanging original training data, offering a solution that is particularly valuable in sensitive domains such as biomedicine. However, training robust FL models often requires substantial computing resources from participating clients, which may not be readily available at institutions such as hospitals. While cloud platforms offer on-demand access to such resources, their usage can incur significant costs, particularly in distributed training scenarios where poor coordination strategies can lead to substantial resource wastage. To address this, we introduce FedCostAware, a cost-aware scheduling algorithm designed to optimize synchronous FL on cloud spot instances. FedCostAware addresses the challenges of training on spot instances and different client budgets by employing intelligent management of the lifecycle of spot instances. This approach minimizes resource idle time and overall expenses. Comprehensive experiments across multiple datasets demonstrate that FedCostAware significantly reduces cloud computing costs compared to conventional spot and on-demand schemes, enhancing the accessibility and affordability of FL.

cs.DC

Neural reservoir control of a soft bio-hybrid arm

A long-standing engineering problem, the control of soft robots is difficult because of their highly non-linear, heterogeneous, anisotropic, and distributed nature. Here, bridging engineering and biology, a neural reservoir is employed for the dynamic control of a bio-hybrid model arm made of multiple muscle-tendon groups enveloping an elastic spine. We show how the use of reservoirs facilitates simultaneous control and self-modeling across a set of challenging tasks, outperforming classic neural network approaches. Further, by implementing a spiking reservoir on neuromorphic hardware, energy efficiency is achieved, with nearly two-orders of magnitude improvement relative to standard CPUs, with implications for the on-board control of untethered, small-scale soft robots.

cs.RO

Introducing 3D Representation for Medical Image Volume-to-Volume Translation via Score Fusion

In volume-to-volume translations in medical images, existing models often struggle to capture the inherent volumetric distribution using 3D voxelspace representations, due to high computational dataset demands. We present Score-Fusion, a novel volumetric translation model that effectively learns 3D representations by ensembling perpendicularly trained 2D diffusion models in score function space. By carefully initializing our model to start with an average of 2D models as in TPDM, we reduce 3D training to a fine-tuning process and thereby mitigate both computational and data demands. Furthermore, we explicitly design the 3D model's hierarchical layers to learn ensembles of 2D features, further enhancing efficiency and performance. Moreover, Score-Fusion naturally extends to multi-modality settings, by fusing diffusion models conditioned on different inputs for flexible, accurate integration. We demonstrate that 3D representation is essential for better performance in downstream recognition tasks, such as tumor segmentation, where most segmentation models are based on 3D representation. Extensive experiments demonstrate that Score-Fusion achieves superior accuracy and volumetric fidelity in 3D medical image super-resolution and modality translation. Beyond these improvements, our work also provides broader insight into learning-based approaches for score function fusion.

cs.CV

Evidential Deep Learning for Uncertainty Quantification and Out-of-Distribution Detection in Jet Identification using Deep Neural Networks

Current methods commonly used for uncertainty quantification (UQ) in deep learning (DL) models utilize Bayesian methods which are computationally expensive and time-consuming. In this paper, we provide a detailed study of UQ based on evidential deep learning (EDL) for deep neural network models designed to identify jets in high energy proton-proton collisions at the Large Hadron Collider and explore its utility in anomaly detection. EDL is a DL approach that treats learning as an evidence acquisition process designed to provide confidence (or epistemic uncertainty) about test data. Using publicly available datasets for jet classification benchmarking, we explore hyperparameter optimizations for EDL applied to the challenge of UQ for jet identification. We also investigate how the uncertainty is distributed for each jet class, how this method can be implemented for the detection of anomalies, how the uncertainty compares with Bayesian ensemble methods, and how the uncertainty maps onto latent spaces for the models. Our studies uncover some pitfalls of EDL applied to anomaly detection and a more effective way to quantify uncertainty from EDL as compared with the foundational EDL setup. These studies illustrate a methodological approach to interpreting EDL in jet classification models, providing new insights on how EDL quantifies uncertainty and detects out-of-distribution data which may lead to improved EDL methods for DL models applied to classification tasks.

hep-ex

TinyHelen's First Curriculum: Training and Evaluating Tiny Language Models in a Simpler Language Environment

Training language models (LMs) and their application agents is increasingly costly due to large datasets and models, making test failures difficult to bear. Simplified language environments serve as primordial training and testing grounds, retaining essential commonsense and communication skills but in a more digestible form, potentially enhancing the learning efficiency of LMs, and thus reducing the required model size and data volume for effective training and evaluation. In these simplified language environments, workable strategies for small models, datasets, and agents may be adaptable to larger models, datasets, and agents in complex language environments. To create such environments, we focus on two aspects: i) minimizing language dataset noise and complexity, and ii) preserving the essential text distribution characteristics. Unlike previous methods, we propose a pipeline to refine text data by eliminating noise, minimizing vocabulary, and maintaining genre-specific patterns (e.g., for books, conversation, code, etc.). Implementing this pipeline with large LMs, we have created a leaner suite of LM training and evaluation datasets: 71M Leaner-Pretrain, 7M Leaner-Instruct, Leaner-Glue for assessing linguistic proficiency, and Leaner-Eval for testing instruction-following ability. Our experiments show that leaner pre-training boosts LM learning efficiency. Tiny LMs trained on these datasets outperform those trained on original datasets in instruction-following across different language granularity levels. Moreover, the Leaner-Pretrain dataset's alignment with conventional large LM training sets enables resource-optimized analysis of how learning objectives, model architectures, and training techniques impact performance on language modeling and downstream tasks. Our code and datasets are available at https://github.com/EmpathYang/TinyHelen.git.

cs.CL

ORBIT: Cost-Effective Dataset Curation for Large Language Model Domain Adaptation with an Astronomy Case Study

Recent advances in language modeling demonstrate the need for high-quality domain-specific training data, especially for tasks that require specialized knowledge. General-purpose models, while versatile, often lack the depth needed for expert-level tasks because of limited domain-specific information. Domain adaptation training can enhance these models, but it demands substantial, high-quality data. To address this, we propose ORBIT, a cost-efficient methodology for curating massive, high-quality domain-specific datasets from noisy web sources, tailored for training specialist large language models. Using astronomy as a primary case study, we refined the 1.3T-token FineWeb-Edu dataset into a high-quality, 10B-token subset focused on astronomy. Fine-tuning \textsc{LLaMA-3-8B} on a 1B-token astronomy subset improved performance on the MMLU astronomy benchmark from 69\% to 76\% and achieved top results on AstroBench, an astronomy-specific benchmark. Moreover, our model (Orbit-LLaMA) outperformed \textsc{LLaMA-3-8B-base}, with GPT-4o evaluations preferring it in 73\% of cases across 1000 astronomy-specific questions. Additionally, we validated ORBIT's generalizability by applying it to law and medicine, achieving a significant improvement of data quality compared to an unfiltered baseline. We open-source the ORBIT methodology, including the curated datasets, the codebase, and the resulting model at \href{https://github.com/ModeEric/ORBIT-Llama}{https://github.com/ModeEric/ORBIT-Llama}.

cs.CL

Transforming the Hybrid Cloud for Emerging AI Workloads

This white paper, developed through close collaboration between IBM Research and UIUC researchers within the IIDAI Institute, envisions transforming hybrid cloud systems to meet the growing complexity of AI workloads through innovative, full-stack co-design approaches, emphasizing usability, manageability, affordability, adaptability, efficiency, and scalability. By integrating cutting-edge technologies such as generative and agentic AI, cross-layer automation and optimization, unified control plane, and composable and adaptive system architecture, the proposed framework addresses critical challenges in energy efficiency, performance, and cost-effectiveness. Incorporating quantum computing as it matures will enable quantum-accelerated simulations for materials science, climate modeling, and other high-impact domains. Collaborative efforts between academia and industry are central to this vision, driving advancements in foundation models for material design and climate solutions, scalable multimodal data processing, and enhanced physics-based AI emulators for applications like weather forecasting and carbon sequestration. Research priorities include advancing AI agentic systems, LLM as an Abstraction (LLMaaA), AI model optimization and unified abstractions across heterogeneous infrastructure, end-to-end edge-cloud transformation, efficient programming model, middleware and platform, secure infrastructure, application-adaptive cloud systems, and new quantum-classical collaborative workflows. These ideas and solutions encompass both theoretical and practical research questions, requiring coordinated input and support from the research community. This joint initiative aims to establish hybrid clouds as secure, efficient, and sustainable platforms, fostering breakthroughs in AI-driven applications and scientific discovery across academia, industry, and society.

cs.DC

RL-Pruner: Structured Pruning Using Reinforcement Learning for CNN Compression and Acceleration

Convolutional Neural Networks (CNNs) have demonstrated exceptional performance in recent years. Compressing these models not only reduces storage requirements, making deployment to edge devices feasible, but also accelerates inference, thereby reducing latency and computational costs. Structured pruning, which removes filters at the layer level, directly modifies the model architecture. This approach achieves a more compact architecture while maintaining target accuracy, ensuring that the compressed model retains good compatibility and hardware efficiency. Our method is based on a key observation: filters in different layers of a neural network have varying importance to the model's performance. When the number of filters to prune is fixed, the optimal pruning distribution across different layers is uneven to minimize performance loss. Layers that are more sensitive to pruning should account for a smaller proportion of the pruning distribution. To leverage this insight, we propose RL-Pruner, which uses reinforcement learning to learn the optimal pruning distribution. RL-Pruner can automatically extract dependencies between filters in the input model and perform pruning, without requiring model-specific pruning implementations. We conducted experiments on models such as GoogleNet, ResNet, and MobileNet, comparing our approach to other structured pruning methods to validate its effectiveness. Our code is available at https://github.com/Beryex/RLPruner-CNN.

cs.CV

AIDOVECL: AI-generated Dataset of Outpainted Vehicles for Eye-level Classification and Localization

Image labeling is a critical bottleneck in the development of computer vision technologies, often constraining machine learning performance due to the time-intensive nature of manual annotations. This work introduces a novel approach that leverages outpainting to mitigate annotated data scarcity by generating artificial contexts and annotations, significantly reducing labeling efforts. We apply this technique to a particularly acute challenge in autonomous driving, urban planning, and environmental monitoring: the lack of diverse, eye-level vehicle images from desired classes. Our dataset comprises AI-generated vehicle images obtained by detecting and cropping vehicles from manually selected seed images, which are then outpainted onto larger canvases to simulate varied real-world conditions. The outpainted images include detailed annotations, providing high-quality ground truth data. Advanced outpainting techniques and image quality assessments ensure visual fidelity and contextual relevance. Ablation results show that incorporating AIDOVECL improves overall detection performance by up to about 10%, and delivers gains of up to about 40% in settings with greater diversity of context, object scale, and placement, with underrepresented classes achieving up to about 50% higher true positives. AIDOVECL enhances vehicle detection by augmenting real training data and supporting evaluation across diverse scenarios. By demonstrating outpainting as an automatic annotation paradigm, it offers a practical and versatile solution for building fine-grained datasets with reduced labeling effort across multiple machine learning domains. The code and links to datasets are available for further research and replication at https://github.com/amir-kazemi/aidovecl.

cs.CV