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Wei Gao

Publications and source records attributed to Wei Gao.

326 records · Page 19Linked to original sources

One-Pass AUC Optimization

AUC is an important performance measure and many algorithms have been devoted to AUC optimization, mostly by minimizing a surrogate convex loss on a training data set. In this work, we focus on one-pass AUC optimization that requires only going through the training data once without storing the entire training dataset, where conventional online learning algorithms cannot be applied directly because AUC is measured by a sum of losses defined over pairs of instances from different classes. We develop a regression-based algorithm which only needs to maintain the first and second order statistics of training data in memory, resulting a storage requirement independent from the size of training data. To efficiently handle high dimensional data, we develop a randomized algorithm that approximates the covariance matrices by low rank matrices. We verify, both theoretically and empirically, the effectiveness of the proposed algorithm.

cs.LG↗

High-Speed Propulsion of Flexible Nanowire Motors: Theory and Experiments

Micro/nano-scale propulsion has attracted considerable recent attention due to its promise for biomedical applications such as targeted drug delivery. In this paper, we report on a new experimental design and theoretical modelling of high-speed fuel-free magnetically-driven propellers which exploit the flexibility of nanowires for propulsion. These readily prepared nanomotors display both high dimensional propulsion velocities (up to ~ 21 micrometer per second) and dimensionless speeds (in body lengths per revolution) when compared with natural microorganisms and other artificial propellers. Their propulsion characteristics are studied theoretically using an elastohydrodynamic model which takes into account the elasticity of the nanowire and its hydrodynamic interaction with the fluid medium. The critical role of flexibility in this mode of propulsion is illustrated by simple physical arguments, and is quantitatively investigated with the help of an asymptotic analysis for small-amplitude swimming. The theoretical predictions are then compared with experimental measurements and we obtain good agreement. Finally, we demonstrate the operation of these nanomotors in a real biological environment (human serum), emphasizing the robustness of their propulsion performance and their promise for biomedical applications.

physics.flu-dyn↗