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Wei Jin

Publications and source records attributed to Wei Jin.

At least 37 records · Page 2Linked to original sources

STReasoner: Empowering LLMs for Spatio-Temporal Reasoning in Time Series via Spatial-Aware Reinforcement Learning

Spatio-temporal reasoning in time series involves the explicit synthesis of temporal dynamics, spatial dependencies, and textual context. This capability is vital for high-stakes decision-making in systems such as traffic networks, power grids, and disease propagation. However, the field remains underdeveloped because most existing works prioritize predictive accuracy over reasoning. To address the gap, we introduce ST-Bench, a benchmark consisting of four core tasks, including etiological reasoning, entity identification, correlation reasoning, and in-context forecasting, developed via a network SDE-based multi-agent data synthesis pipeline. We then propose STReasoner, which empowers LLM to integrate time series, graph structure, and text for explicit reasoning. To promote spatially grounded logic, we introduce S-GRPO, a reinforcement learning algorithm that rewards performance gains specifically attributable to spatial information. Experiments show that STReasoner achieves average accuracy gains between 17% and 135% at only 0.004X the cost of proprietary models and generalizes robustly to real-world data.

cs.CL↗

TimeRecipe: A Time-Series Forecasting Recipe via Benchmarking Module Level Effectiveness

Time-series forecasting is an essential task with wide real-world applications across domains. While recent advances in deep learning have enabled time-series forecasting models with accurate predictions, there remains considerable debate over which architectures and design components, such as series decomposition or normalization, are most effective under varying conditions. Existing benchmarks primarily evaluate models at a high level, offering limited insight into why certain designs work better. To mitigate this gap, we propose TimeRecipe, a unified benchmarking framework that systematically evaluates time-series forecasting methods at the module level. TimeRecipe conducts over 10,000 experiments to assess the effectiveness of individual components across a diverse range of datasets, forecasting horizons, and task settings. Our results reveal that exhaustive exploration of the design space can yield models that outperform existing state-of-the-art methods and uncover meaningful intuitions linking specific design choices to forecasting scenarios. Furthermore, we release a practical toolkit within TimeRecipe that recommends suitable model architectures based on these empirical insights. The benchmark is available at: https://github.com/AdityaLab/TimeRecipe.

cs.LG↗

ECG-MoE: Mixture-of-Expert Electrocardiogram Foundation Model

Electrocardiography (ECG) analysis is crucial for cardiac diagnosis, yet existing foundation models often fail to capture the periodicity and diverse features required for varied clinical tasks. We propose ECG-MoE, a hybrid architecture that integrates multi-model temporal features with a cardiac period-aware expert module. Our approach uses a dual-path Mixture-of-Experts to separately model beat-level morphology and rhythm, combined with a hierarchical fusion network using LoRA for efficient inference. Evaluated on five public clinical tasks, ECG-MoE achieves state-of-the-art performance with 40% faster inference than multi-task baselines.

cs.AI↗

Pre-training Epidemic Time Series Forecasters with Compartmental Prototypes

Accurate epidemic forecasting is crucial for outbreak preparedness, but existing data-driven models are often brittle. Typically trained on a single pathogen, they struggle with data scarcity during new outbreaks and fail under distribution shifts caused by viral evolution or interventions. However, decades of surveillance data and the design of various compartmental models from diverse diseases offer an untapped source of transferable knowledge. To leverage the collective lessons from history, we propose CAPE, the first open-source pre-trained model for epidemic forecasting. Unlike existing time series foundation models that overlook epidemiological challenges, CAPE models epidemic dynamics as mixtures of latent compartmental population states, termed \textit{compartmental prototypes}. It models a flexible dictionary of compartment prototypes directly from a large collection of simulation data, enabling each outbreak to be expressed as a time-varying mixture that links observed infections to latent population states. To promote robust generalization, CAPE adopts the next-token-prediction paradigm during pre-training with lightweight epidemic-aware regularization that aligns the learned prototypes with epidemiological semantics. On a comprehensive benchmark spanning 17 diseases, CAPE significantly outperforms strong baselines with zero-shot forecasting. This work represents a principled step toward pre-trained epidemic models that are both transferable and epidemiologically grounded. We provide our code in: https://github.com/nuuuh/CAPE.

cs.LG↗

Patient-Conditioned Adaptive Offsets for Reliable Diagnosis across Subgroups

AI models for medical diagnosis often exhibit uneven performance across patient populations due to heterogeneity in disease prevalence, imaging appearance, and clinical risk profiles. Existing algorithmic fairness approaches typically seek to reduce such disparities by suppressing sensitive attributes. However, in medical settings these attributes often carry essential diagnostic information, and removing them can degrade accuracy and reliability, particularly in high-stakes applications. In contrast, clinical decision making explicitly incorporates patient context when interpreting diagnostic evidence, suggesting a different design direction for subgroup-aware models. In this paper, we introduce HyperAdapt, a patient-conditioned adaptation framework that improves subgroup reliability while maintaining a shared diagnostic model. Clinically relevant attributes such as age and sex are encoded into a compact embedding and used to condition a hypernetwork-style module, which generates small residual modulation parameters for selected layers of a shared backbone. This design preserves the general medical knowledge learned by the backbone while enabling targeted adjustments that reflect patient-specific variability. To ensure efficiency and robustness, adaptations are constrained through low-rank and bottlenecked parameterizations, limiting both model complexity and computational overhead. Experiments across multiple public medical imaging benchmarks demonstrate that the proposed approach consistently improves subgroup-level performance without sacrificing overall accuracy. On the PAD-UFES-20 dataset, our method outperforms the strongest competing baseline by 4.1% in recall and 4.4% in F1 score, with larger gains observed for underrepresented patient populations.

cs.CV↗

TimeDistill: Efficient Long-Term Time Series Forecasting with MLP via Cross-Architecture Distillation

Transformer-based and CNN-based methods demonstrate strong performance in long-term time series forecasting. However, their high computational and storage requirements can hinder large-scale deployment. To address this limitation, we propose integrating lightweight MLP with advanced architectures using knowledge distillation (KD). Our preliminary study reveals different models can capture complementary patterns, particularly multi-scale and multi-period patterns in the temporal and frequency domains. Based on this observation, we introduce TimeDistill, a cross-architecture KD framework that transfers these patterns from teacher models (e.g., Transformers, CNNs) to MLP. Additionally, we provide a theoretical analysis, demonstrating that our KD approach can be interpreted as a specialized form of mixup data augmentation. TimeDistill improves MLP performance by up to 18.6%, surpassing teacher models on eight datasets. It also achieves up to 7X faster inference and requires 130X fewer parameters. Furthermore, we conduct extensive evaluations to highlight the versatility and effectiveness of TimeDistill.

cs.LG↗

Suspended waveguide-enhanced near-infrared photothermal spectroscopy for ppb-level molecular gas sensing on a chalcogenide chip

On-chip waveguide sensors have attracted significant attention recently due to their potential for high level integration. However, so far on-chip gas sensing based on traditional laser absorption spectroscopy has demonstrated low detection sensitivity, due to weak light-gas interaction over a limited interaction distance. On-chip photothermal spectroscopy (PTS) appears to be a powerful technique to achieve higher sensitivity, its performance is yet constrained to parts-per-million (ppm)-level due to small fraction of evanescent field in the light-gas interaction zone and fast thermal dissipation through the solid substrate. Herein, we demonstrated suspended chalcogenide glass waveguide (ChGW)-enhanced PTS that overcomes these limitations, enabling highly sensitive parts-per-billion (ppb)-level molecular gas sensing. We fabricated a nanoscale suspended ChGW with low loss of 2.6 dB/cm using CMOS-compatible two-step patterning process. By establishing an equivalent PTS model to guide the optimization of the ChGW geometry, we achieved a 4-fold increase in the absorption-induced heat source power and a 10.6-fold decrease in the equivalent heat conductivity, resulting in a 45-fold enhancement in photothermal phase modulation efficiency over the non-suspended waveguides. Combining with a high-contrast waveguide facet-formed Fabry-Perot interferometer, we achieved an unprecedented acetylene detection limit of 330 ppb, a large dynamic range close to 6 orders of magnitude, and a fast response of less than 1 s. The overall system exhibits a noise-equivalent absorption coefficient of 3.8x10-7 cm-1, setting a new benchmark for photonic waveguide gas sensors to the best of our knowledge. This work provides a key advancement towards prototyping an integrated sensor-on-a-chip for highly sensitive and background-free photonic sensing applications.

physics.optics↗

Score-based Conditional Out-of-Distribution Augmentation for Graph Covariate Shift

Distribution shifts between training and testing datasets significantly impair the model performance on graph learning. A commonly-taken causal view in graph invariant learning suggests that stable predictive features of graphs are causally associated with labels, whereas varying environmental features lead to distribution shifts. In particular, covariate shifts caused by unseen environments in test graphs underscore the critical need for out-of-distribution (OOD) generalization. Existing graph augmentation methods designed to address the covariate shift often disentangle the stable and environmental features in the input space, and selectively perturb or mixup the environmental features. However, such perturbation-based methods heavily rely on an accurate separation of stable and environmental features, and their exploration ability is confined to existing environmental features in the training distribution. To overcome these limitations, we introduce a novel distributional augmentation approach enabled by a tailored score-based conditional graph generation strategies to explore and synthesize unseen environments while preserving the validity and stable features of overall graph patterns. Our comprehensive empirical evaluations demonstrate the enhanced effectiveness of our method in improving graph OOD generalization.

cs.LG↗

Bayesian Causal Discovery with Cycles and Latent Confounders

Learning causality from observational data has received increasing interest across various scientific fields. However, most existing methods assume the absence of latent confounders and restrict the underlying causal graph to be acyclic, assumptions that are often violated in many real-world applications. In this paper, we address these challenges by proposing a novel framework for causal discovery that accommodates both cycles and latent confounders. By leveraging the identifiability results from noisy independent component analysis and recent advances in factor analysis, we establish the unique causal identifiability under mild conditions. Building on this foundation, we further develop a fully Bayesian approach for causal structure learning, called BayCausal, and evaluate its identifiability, utility, and superior performance against state-of-the-art alternatives through extensive simulation studies. Application to a dataset from the Women's Interagency HIV Study yields interpretable and clinically meaningful insights. To facilitate broader applications, we have implemented BayCausal in an R package, BayCausal, which is the first publicly available software capable of achieving unique causal identification in the presence of both cycles and latent confounders.

stat.ME↗

Dual slow-light enhanced photothermal gas spectroscopy on a silicon chip

Integrated photonic sensors have attracted significant attention recently for their potential for high-density integration. However, they face challenges in sensing gases with high sensitivity due to weak light-gas interaction. Slow light, which dramatically intensifies light-matter interaction through spatial compression of optical energy, provides a promising solution. Herein, we demonstrate a dual slow-light scheme for enhancing the sensitivity of photothermal spectroscopy (PTS) with a suspended photonic crystal waveguide (PhCW) on a CMOS-compatible silicon platform. By tailoring the dispersion of the PhCW to generate structural slow light to enhance pump absorption and probe phase modulation, we achieve a photothermal efficiency of 3.6x10-4 rad cm ppm-1 mW-1 m-1, over 1-3 orders of magnitude higher than the strip waveguides and optical fibers. With a 1-mm-long sensing PhCW incorporated in a stabilized on-chip Mach-Zehnder interferometer with a footprint of 0.6 mm2, we demonstrate acetylene detection with a sensitivity of 1.4x10-6 in terms of noise-equivalent absorption and length product (NEAL), the best among the reported photonic waveguide gas sensors to our knowledge. The dual slow-light enhanced PTS paves the way for integrated photonic gas sensors with high sensitivity, miniaturization, and cost-effective mass production.

physics.optics↗

An Adaptive Machine Learning Triage Framework for Predicting Alzheimer's Disease Progression

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power of PET scans and CSF biomarker analysis, which are prohibitively expensive to obtain for every patient. To address this cost-accuracy dilemma, we design a two-stage machine learning framework that selectively obtains advanced, costly features based on their predicted "value of information". We apply our framework to predict AD progression for MCI patients using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Our framework reduces the need for advanced testing by 20% while achieving a test AUROC of 0.929, comparable to the model that uses both basic and advanced features (AUROC=0.915, p=0.1010). We also provide an example interpretability analysis showing how one may explain the triage decision. Our work presents an interpretable, data-driven framework that optimizes AD diagnostic pathways and balances accuracy with cost, representing a step towards making early, reliable AD prediction more accessible in real-world practice. Future work should consider multiple categories of advanced features and larger-scale validation.

cs.LG↗

GC4NC: A Benchmark Framework for Graph Condensation on Node Classification with New Insights

Graph condensation (GC) is an emerging technique designed to learn a significantly smaller graph that retains the essential information of the original graph. This condensed graph has shown promise in accelerating graph neural networks while preserving performance comparable to those achieved with the original, larger graphs. Additionally, this technique facilitates downstream applications like neural architecture search and deepens our understanding of redundancies in large graphs. Despite the rapid development of GC methods, particularly for node classification, a unified evaluation framework is still lacking to systematically compare different GC methods or clarify key design choices for improving their effectiveness. To bridge these gaps, we introduce \textbf{GC4NC}, a comprehensive framework for evaluating diverse GC methods on node classification across multiple dimensions including performance, efficiency, privacy preservation, denoising ability, NAS effectiveness, and transferability. Our systematic evaluation offers novel insights into how condensed graphs behave and the critical design choices that drive their success. These findings pave the way for future advancements in GC methods, enhancing both performance and expanding their real-world applications. Our code is available at https://github.com/Emory-Melody/GraphSlim/tree/main/benchmark.

cs.LG↗

PPG-Distill: Efficient Photoplethysmography Signals Analysis via Foundation Model Distillation

Photoplethysmography (PPG) is widely used in wearable health monitoring, yet large PPG foundation models remain difficult to deploy on resource-limited devices. We present PPG-Distill, a knowledge distillation framework that transfers both global and local knowledge through prediction-, feature-, and patch-level distillation. PPG-Distill incorporates morphology distillation to preserve local waveform patterns and rhythm distillation to capture inter-patch temporal structures. On heart rate estimation and atrial fibrillation detection, PPG-Distill improves student performance by up to 21.8% while achieving 7X faster inference and reducing memory usage by 19X, enabling efficient PPG analysis on wearables.

cs.LG↗

A note on the second-largest number of dissociation sets in connected graphs

A subset of vertices is called a dissociation set if it induces a subgraph with vertex degree at most one. Recently, Yuan et al. established the upper bound of the maximum number of dissociation sets among all connected graphs of order n and characterized the corresponding extremal graphs.They also proposed a question regarding the second-largest number of dissociation sets among all connected graphs of order n and the corresponding extremal graphs. In this paper, we give a positive answer to this question.

math.CO↗

Generalist vs Specialist Time Series Foundation Models: Investigating Potential Emergent Behaviors in Assessing Human Health Using PPG Signals

Foundation models are large-scale machine learning models that are pre-trained on massive amounts of data and can be adapted for various downstream tasks. They have been extensively applied to tasks in Natural Language Processing and Computer Vision with models such as GPT, BERT, and CLIP. They are now also increasingly gaining attention in time-series analysis, particularly for physiological sensing. However, most time series foundation models are specialist models - with data in pre-training and testing of the same type, such as Electrocardiogram, Electroencephalogram, and Photoplethysmogram (PPG). Recent works, such as MOMENT, train a generalist time series foundation model with data from multiple domains, such as weather, traffic, and electricity. This paper aims to conduct a comprehensive benchmarking study to compare the performance of generalist and specialist models, with a focus on PPG signals. Through an extensive suite of total 51 tasks covering cardiac state assessment, laboratory value estimation, and cross-modal inference, we comprehensively evaluate both models across seven dimensions, including win score, average performance, feature quality, tuning gain, performance variance, transferability, and scalability. These metrics jointly capture not only the models' capability but also their adaptability, robustness, and efficiency under different fine-tuning strategies, providing a holistic understanding of their strengths and limitations for diverse downstream scenarios. In a full-tuning scenario, we demonstrate that the specialist model achieves a 27% higher win score. Finally, we provide further analysis on generalization, fairness, attention visualizations, and the importance of training data choice.

cs.LG↗

U-Cast: Learning Hierarchical Structures for High-Dimensional Time Series Forecasting

Time series forecasting (TSF) is a central problem in time series analysis. However, as the number of channels in time series datasets scales to the thousands or more, a scenario we define as High-Dimensional Time Series Forecasting (HDTSF), it introduces significant new modeling challenges that are often not the primary focus of traditional TSF research. HDTSF is challenging because the channel correlation often forms complex and hierarchical patterns. Existing TSF models either ignore these interactions or fail to scale as dimensionality grows. To address this issue, we propose U-Cast, a channel-dependent forecasting architecture that learns latent hierarchical channel structures with an innovative query-based attention. To disentangle highly correlated channel representation, U-Cast adds a full-rank regularization during training. We also release Time-HD, the first benchmark of large, diverse, high-dimensional datasets. Our theory shows that exploiting cross-channel information lowers forecasting risk, and experiments on Time-HD demonstrate that U-Cast surpasses strong baselines in both accuracy and efficiency. Together, U-Cast and Time-HD provide a solid basis for future HDTSF research.

cs.LG↗

A Unified AI Approach for Continuous Monitoring of Human Health and Diseases from Intensive Care Unit to Home with Physiological Foundation Models (UNIPHY+)

We present UNIPHY+, a unified physiological foundation model (physioFM) framework designed to enable continuous human health and diseases monitoring across care settings using ubiquitously obtainable physiological data. We propose novel strategies for incorporating contextual information during pretraining, fine-tuning, and lightweight model personalization via multi-modal learning, feature fusion-tuning, and knowledge distillation. We advocate testing UNIPHY+ with a broad set of use cases from intensive care to ambulatory monitoring in order to demonstrate that UNIPHY+ can empower generalizable, scalable, and personalized physiological AI to support both clinical decision-making and long-term health monitoring.

cs.AI↗

Graph ODEs and Beyond: A Comprehensive Survey on Integrating Differential Equations with Graph Neural Networks

Graph Neural Networks (GNNs) and differential equations (DEs) are two rapidly advancing areas of research that have shown remarkable synergy in recent years. GNNs have emerged as powerful tools for learning on graph-structured data, while differential equations provide a principled framework for modeling continuous dynamics across time and space. The intersection of these fields has led to innovative approaches that leverage the strengths of both, enabling applications in physics-informed learning, spatiotemporal modeling, and scientific computing. This survey aims to provide a comprehensive overview of the burgeoning research at the intersection of GNNs and DEs. We will categorize existing methods, discuss their underlying principles, and highlight their applications across domains such as molecular modeling, traffic prediction, and epidemic spreading. Furthermore, we identify open challenges and outline future research directions to advance this interdisciplinary field. A comprehensive paper list is provided at https://github.com/Emory-Melody/Awesome-Graph-NDEs. This survey serves as a resource for researchers and practitioners seeking to understand and contribute to the fusion of GNNs and DEs

cs.LG↗