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Wei Li

Publications and source records attributed to Wei Li.

At least 199 records · Page 11Linked to original sources

A Wearable ECG Device for Differentiating Hypertrophic Cardiomyopathy from Acquired Left Ventricular Hypertrophy

Hypertrophic Cardiomyopathy (HCM) is a genetic heart disease affecting approximately 1 in 500 people and is the leading cause of sudden cardiac death in young athletes. Current diagnostic methods -- cardiovascular magnetic resonance (CMR), echocardiography, and genetic testing -- are limited by high costs, operator dependency, or insufficient accuracy, while standard electrocardiogram (ECG) analysis cannot reliably distinguish HCM from acquired left ventricular hypertrophy (LVH). This paper presents a wearable ECG device paired with a classification algorithm that differentiates HCM from acquired LVH using ECG signals alone. The portable device integrates a 3-lead electrode system, an AD8232 signal conditioning module, an Arduino Nano 33 BLE microcontroller, and a lithium polymer battery. The algorithm extracts two quantitative indices -- HCM Index~1 and HCM Index~2 -- from each heartbeat and classifies patients via dual statistical thresholds. Validation on 483 LVH patients (PhysioNet) and 29 HCM patients (digitized clinical records) yields 75.86\% sensitivity, 99.17\% specificity, and an F1-score of 80.00\%. Leave-one-out cross-validation confirms generalizability, with cross-validated sensitivity of 72.41\%, specificity of 98.96\%, and F1-score of 76.36\% (95\% confidence intervals reported). A digitization confound analysis demonstrates that the classification is driven by physiological cardiac features rather than data source artifacts. A simulated device acquisition chain analysis confirms that the wearable hardware's signal characteristics are compatible with the classification algorithm. The system offers a promising tool for affordable HCM screening in resource-limited settings.

eess.IV↗

Magnetically Tunable Chiral Phonon Polaritons with Magneto-optical Bound States in the Continuum

Chiral phonon-polaritonic states are of interest for handedness-dependent light-matter interactions, yet their realization and magnetic control remain challenging, while direct magneto-optical tunability of phonon-polaritonic media is limited. Here, we propose a hybrid platform in which an hBN phonon polariton couples to a chiral bound state in the continuum supported by a magneto-optical photonic crystal, enabling strong and selective photonic coupling. The interaction gives rise to pronounced mode splitting and the formation of hybrid states, and their modal composition is quantified by phonon-proportion analysis and described by a coupling theory. Importantly, the hybridization can be controlled by magnetic bias through the magneto-optical response of the photonic component, providing control over the modal composition and spectral response. In addition, the hybrid states exhibit handedness-selective absorption under circularly polarized excitation. This work offers a feasible route toward magnetically tunable chiral phonon-polaritonic devices and hybrid polaritonic functionalities

physics.optics↗

RealSR-R1: Reinforcement Learning for Real-World Image Super-Resolution with Vision-Language Chain-of-Thought

Real-World Image Super-Resolution is one of the most challenging task in image restoration. However, existing methods struggle with an accurate understanding of degraded image content, leading to reconstructed results that are both low-fidelity and unnatural. We present RealSR-R1 in this work, which empowers the RealSR models with understanding and reasoning capabilities. Inspired by the success of Chain of Thought (CoT) in large language models (LLMs), we simulate the human process of handling degraded images and propose the VLCoT framework, which integrates vision and language reasoning. The framework aims to precisely restore image details by progressively generating more comprehensive text and higher-resolution images. To overcome the challenge of traditional supervised learning CoT failing to generalize to real-world scenarios, we introduce, for the first time, Group Relative Policy Optimization (GRPO) into the Real-World Image Super-Resolution task. We propose VLCoT-GRPO as a solution, which designs four reward functions: (1) Format reward, used to standardize the CoT process; (2) Degradation reward, to incentivize accurate degradation estimation; (3) Understanding reward, to ensure the accuracy of the generated content; and (4) Generation reward, where we propose using a visual expert model to evaluate the quality of generated images, encouraging the model to generate more realistic images. Extensive experiments demonstrate that our proposed RealSR-R1 can generate realistic details and accurately understand image content, particularly in semantically rich scenes or images with severe degradation.

cs.CV↗

Towards Knowledgeable Deep Research: Framework and Benchmark

Deep Research (DR) requires LLM agents to autonomously perform multi-step information seeking, processing, and reasoning to generate comprehensive reports. In contrast to existing studies that mainly focus on unstructured web content, a more challenging DR task should additionally utilize structured knowledge to provide a solid data foundation, facilitate quantitative computation, and lead to in-depth analyses. In this paper, we refer to this novel task as Knowledgeable Deep Research (KDR), which requires DR agents to generate reports with both structured and unstructured knowledge. Furthermore, we propose the Hybrid Knowledge Analysis framework (HKA), a multi-agent architecture that reasons over both kinds of knowledge and integrates the texts, figures, and tables into coherent multimodal reports. The key design is the Structured Knowledge Analyzer, which utilizes both coding and vision-language models to produce figures, tables, and corresponding insights. To support systematic evaluation, we construct KDR-Bench, which covers 9 domains, includes 41 expert-level questions, and incorporates a large number of structured knowledge resources (e.g., 1,252 tables). We further annotate the main conclusions and key points for each question and propose three categories of evaluation metrics including general-purpose, knowledge-centric, and vision-enhanced ones. Experimental results demonstrate that HKA consistently outperforms most existing DR agents on general-purpose and knowledge-centric metrics, and even surpasses the Gemini DR agent on vision-enhanced metrics, highlighting its effectiveness in deep, structure-aware knowledge analysis. Finally, we hope this work can serve as a new foundation for structured knowledge analysis in DR agents and facilitate future multimodal DR studies.

cs.AI↗

EthicMind: A Risk-Aware Framework for Ethical-Emotional Alignment in Multi-Turn Dialogue

Intelligent dialogue systems are increasingly deployed in emotionally and ethically sensitive settings, where failures in either emotional attunement or ethical judgment can cause significant harm. Existing dialogue models typically address empathy and ethical safety in isolation, and often fail to adapt their behavior as ethical risk and user emotion evolve across multi-turn interactions. We formulate ethical-emotional alignment in dialogue as an explicit turn-level decision problem, and propose \textsc{EthicMind}, a risk-aware framework that implements this formulation in multi-turn dialogue at inference time. At each turn, \textsc{EthicMind} jointly analyzes ethical risk signals and user emotion, plans a high-level response strategy, and generates context-sensitive replies that balance ethical guidance with emotional engagement, without requiring additional model training. To evaluate alignment behavior under ethically complex interactions, we introduce a risk-stratified, multi-turn evaluation protocol with a context-aware user simulation procedure. Experimental results show that \textsc{EthicMind} achieves more consistent ethical guidance and emotional engagement than competitive baselines, particularly in high-risk and morally ambiguous scenarios.

cs.CL↗

MinerU2.5-Pro: Pushing the Limits of Data-Centric Document Parsing at Scale

Current document parsing methods advance primarily through model architecture innovation, while systematic engineering of training data remains underexplored. Yet state-of-the-art models spanning diverse architectures and parameter scales exhibit highly consistent failure patterns on the same set of hard samples, suggesting that the performance bottleneck stems from shared deficiencies in training data rather than from architectural differences. Building on this finding, we present MinerU2.5-Pro, which advances the state of the art purely through data engineering and training strategy design while retaining the 1.2B-parameter architecture of MinerU2.5 unchanged. At its core is a Data Engine co-designed around coverage, informativeness, and annotation accuracy: Diversity-and-Difficulty-Aware Sampling expands training data from under 10M to 65.5M samples while mitigating distribution shift; Cross-Model Consistency Verification leverages output consensus among heterogeneous models to assess sample difficulty and generate reliable annotations; the Judge-and-Refine pipeline improves annotation quality for hard samples through render-then-verify iterative correction. A three-stage progressive training strategy--large-scale pre-training, hard sample fine-tuning, and GRPO alignment--sequentially exploits these data at different quality tiers. On the evaluation front, we rectify element-matching biases in OmniDocBench v1.5 and introduce a Hard subset, establishing the more discriminative OmniDocBench v1.6 protocol. Without any architectural modification, MinerU2.5-Pro achieves 95.69 on OmniDocBench v1.6, improving over the same-architecture baseline by 2.71 points and surpassing all existing methods, including those based on models with over 200x more parameters.

cs.CV↗

Guiding a Diffusion Model by Swapping Its Tokens

Classifier-Free Guidance (CFG) is a widely used inference-time technique to boost the image quality of diffusion models. Yet, its reliance on text conditions prevents its use in unconditional generation. We propose a simple method to enable CFG-like guidance for both conditional and unconditional generation. The key idea is to generate a perturbed prediction via simple token swap operations, and use the direction between it and the clean prediction to steer sampling towards higher-fidelity distributions. In practice, we swap pairs of most semantically dissimilar token latents in either spatial or channel dimensions. Unlike existing methods that apply perturbation in a global or less constrained manner, our approach selectively exchanges and recomposes token latents, allowing finer control over perturbation and its influence on generated samples. Experiments on MS-COCO 2014, MS-COCO 2017, and ImageNet datasets demonstrate that the proposed Self-Swap Guidance (SSG), when applied to popular diffusion models, outperforms previous condition-free methods in image fidelity and prompt alignment under different set-ups. Its fine-grained perturbation granularity also improves robustness, reducing side-effects across a wider range of perturbation strengths. Overall, SSG extends CFG to a broader scope of applications including both conditional and unconditional generation, and can be readily inserted into any diffusion model as a plug-in to gain immediate improvements.

cs.CV↗

Draw-In-Mind: Rebalancing Designer-Painter Roles in Unified Multimodal Models Benefits Image Editing

In recent years, integrating multimodal understanding and generation into a single unified model has emerged as a promising paradigm. While this approach achieves strong results in text-to-image (T2I) generation, it still struggles with precise image editing. We attribute this limitation to an imbalanced division of responsibilities. The understanding module primarily functions as a translator that encodes user instructions into semantic conditions, while the generation module must simultaneously act as designer and painter, inferring the original layout, identifying the target editing region, and rendering the new content. This imbalance is counterintuitive because the understanding module is typically trained with several times more data on complex reasoning tasks than the generation module. To address this issue, we introduce Draw-In-Mind (DIM), a dataset comprising two complementary subsets: (i) DIM-T2I, containing 14M long-context image-text pairs to enhance complex instruction comprehension; and (ii) DIM-Edit, consisting of 233K chain-of-thought imaginations generated by GPT-4o, serving as explicit design blueprints for image edits. We connect a frozen Qwen2.5-VL-3B with a trainable SANA1.5-1.6B via a lightweight two-layer MLP, and train it on the proposed DIM dataset, resulting in DIM-4.6B-T2I/Edit. Despite its modest parameter scale, DIM-4.6B-Edit achieves SOTA or competitive performance on the ImgEdit and GEdit-Bench benchmarks, outperforming much larger models such as UniWorld-V1 and Step1X-Edit. These findings demonstrate that explicitly assigning the design responsibility to the understanding module provides significant benefits for image editing. Our dataset and models are available at https://github.com/showlab/DIM.

cs.CV↗

iTAG: Inverse Design for Natural Text Generation with Accurate Causal Graph Annotations

A fundamental obstacle to causal discovery from text is the lack of causally annotated text data for use as ground truth, due to high annotation costs. This motivates an important task of generating text with causal graph annotations. Early template-based generation methods sacrifice text naturalness in exchange for high causal graph annotation accuracy. Recent Large Language Model (LLM)-dependent methods directly generate natural text from target graphs through LLMs, but do not guarantee causal graph annotation accuracy. Therefore, we propose iTAG, which performs real-world concept assignment to nodes before converting causal graphs into text in existing LLM-dependent methods. iTAG frames this process as an inverse problem with the causal graph as the target, iteratively examining and refining concept selection through Chain-of-Thought (CoT) reasoning so that the induced relations between concepts are as consistent as possible with the target causal relationships described by the causal graph. iTAG demonstrates both extremely high annotation accuracy and naturalness across extensive tests, and the results of testing text-based causal discovery algorithms with the generated data show high statistical correlation with real-world data. This suggests that iTAG-generated data can serve as a practical surrogate for scalable benchmarking of text-based causal discovery algorithms.

cs.CL↗

Real-time Neural Six-way Lightmaps

Participating media are a pervasive and intriguing visual effect in virtual environments. Unfortunately, rendering such phenomena in real-time is notoriously difficult due to the computational expense of estimating the volume rendering equation. While the six-way lightmaps technique has been widely used in video games to render smoke with a camera-oriented billboard and approximate lighting effects using six precomputed lightmaps, achieving a balance between realism and efficiency, it is limited to pre-simulated animation sequences and is ignorant of camera movement. In this work, we propose a neural six-way lightmaps method to strike a long-sought balance between dynamics and visual realism. Our approach first generates a guiding map from the camera view using ray marching with a large sampling distance to approximate smoke scattering and silhouette. Then, given a guiding map, we train a neural network to predict the corresponding six-way lightmaps. The resulting lightmaps can be seamlessly used in existing game engine pipelines. This approach supports visually appealing rendering effects while enabling real-time user interactivity, including smoke-obstacle interaction, camera movement, and light change. By conducting a series of comprehensive benchmarks, we demonstrate that our method is well-suited for real-time applications, such as games and VR/AR.

cs.GR↗

Unified Medical Image Tokenizer for Autoregressive Synthesis and Understanding

Autoregressive modeling has driven major advances in multimodal AI, yet its application to medical imaging remains constrained by the absence of a unified image tokenizer that simultaneously preserves fine-grained anatomical structures and rich clinical semantics across heterogeneous modalities. Existing approaches jointly optimize image reconstruction and textual semantic objectives, relying on large-scale image-caption pairs and are prone to gradient interference. This is ill-suited for the medical domain where paired data are scarce and abundant unpaired images remain unexploited. This work identifies these issues in building unified medical image tokenizers, and introduces a principled two-stage training framework using visual representation as a bridge to address them. The propose visual representation alignment stage enables the utilization of large-scale unpaired medical images to ensure reconstruction fidelity and establish foundational semantics, alleviating the interference and better preparing for the second stage where fine-grained textual semantics are injected using image-text pairs. The resulting tokenizer, MedITok, is trained on over 33 million medical images spanning 9 modalities and 2 million image-text pairs. MedITok achieves state-of-the-art performance on 30+ benchmarks spanning 9 imaging modalities and 4 task families. It further enables autoregressive modeling for diagnostic and generative applications, serving as a scalable component for future multimodal models with unified synthesis and understanding capabilities in the medical domain. Project page: https://github.com/Masaaki-75/meditok

eess.IV↗

VLM-in-the-Loop: A Plug-In Quality Assurance Module for ECG Digitization Pipelines

ECG digitization could unlock billions of archived clinical records, yet existing methods collapse on real-world images despite strong benchmark numbers. We introduce \textbf{VLM-in-the-Loop}, a plug-in quality assurance module that wraps any digitization backend with closed-loop VLM feedback via a standardized interface, requiring no modification to the underlying digitizer. The core mechanism is \textbf{tool grounding}: anchoring VLM assessment in quantitative evidence from domain-specific signal analysis tools. In a controlled ablation on 200 records with paired ground truth, tool grounding raises verdict consistency from 71\% to 89\% and doubles fidelity separation ($Δ$PCC 0.03 $\rightarrow$ 0.08), with the effect replicating across three VLMs (Claude Opus~4, GPT-4o, Gemini~2.5 Pro), confirming a pattern-level rather than model-specific gain. Deployed across four backends, the module improves every one: 29.4\% of borderline leads improved on our pipeline; 41.2\% of failed limb leads recovered on ECG-Digitiser; valid leads per image doubled on Open-ECG-Digitizer (2.5 $\rightarrow$ 5.8). On 428 real clinical HCM images, the integrated system reaches 98.0\% Excellent quality. Both the plug-in architecture and tool-grounding mechanism are domain-parametric, suggesting broader applicability wherever quality criteria are objectively measurable.

cs.CV↗

HLC: A High-Quality Lightweight Mezzanine Codec Featuring High-Throughput Palette

Existing mezzanine image codecs lack specialized screen content coding tools and therefore struggle to maintain high image quality under bandwidth constraints, especially in areas with dense text. Although distribution codecs offer advanced screen content compression techniques, their high computational complexity makes them impractical for mezzanine coding. To address this shortfall, we introduce the High-quality Lightweight Codec (HLC), a solution centered on enabling practical, high-throughput palette for mezzanine coding. The core innovation is a novel data-dependency-free palette that eliminates the throughput bottlenecks. To ensure its effectiveness across all content, a co-designed rate-distortion optimization module arbitrates between the palette and traditional prediction modes, while a data reuse strategy between rate estimation and entropy coding minimizes the overall hardware resources required for the system. Experimental results show that, compared with a 4K@120fps JPEG-XS encoder, HLC achieves the same throughput while using only half the LUT resources and delivers BD-PSNR improvements of 3.461dB, 3.299dB, and 5.312dB on gaming, natural, and text content datasets, respectively.

cs.AR↗

Thinking with Camera: A Unified Multimodal Model for Camera-Centric Understanding and Generation

Camera-centric understanding and generation are two cornerstones of spatial intelligence, yet they are typically studied in isolation. We present Puffin, a unified camera-centric multimodal model that extends spatial awareness along the camera dimension. Puffin integrates language regression and diffusion-based generation to interpret and create scenes from arbitrary viewpoints. To bridge the modality gap between cameras and vision-language, we introduce a novel paradigm that treats camera as language, enabling thinking with camera. This guides the model to align spatially grounded visual cues with photographic terminology while reasoning across geometric context. Puffin is trained on Puffin-4M, a large-scale dataset of 4 million vision-language-camera triplets. We incorporate both global camera parameters and pixel-wise camera maps, yielding flexible and reliable spatial generation. Experiments demonstrate Puffin superior performance over specialized models for camera-centric generation and understanding. With instruction tuning, Puffin generalizes to diverse cross-view tasks such as spatial imagination, world exploration, and photography guidance. We will release the code, models, dataset pipeline, and benchmark to advance multimodal spatial intelligence research.

cs.CV↗

Identifying Causal Effects Using Instrumental Variables from the Auxiliary Dataset

Instrumental variable approaches have gained popularity for estimating causal effects in the presence of unmeasured confounders. However, the availability of instrumental variables in the primary dataset is often challenged due to stringent and untestable assumptions. This paper presents a novel method to identify and estimate causal effects by utilizing instrumental variables from the auxiliary dataset, incorporating a structural equation model, even in scenarios with nonlinear treatment effects. Our approach involves using two datasets: one called the primary dataset with joint observations of treatment and outcome, and another auxiliary dataset providing information about the instrument and treatment. Our strategy differs from most existing methods by not depending on the simultaneous measurements of instrument and outcome. The central idea for identifying causal effects is to establish a valid substitute through the auxiliary dataset, addressing unmeasured confounders. This is achieved by developing a control function and projecting it onto the function space spanned by the treatment variable. We then propose a three-step estimator for estimating causal effects and derive its asymptotic results. We illustrate the proposed estimator through simulation studies, and the results demonstrate favorable performance. We also conduct a real data analysis to evaluate the causal effect between vitamin D status and body mass index.

stat.ME↗

Mediation analysis with unmeasured confounding between parallel mediators and outcome

Mediation analysis extending beyond single mediators has gained significant attention in recent years. However, related methods often assume the absence of unmeasured mediator-outcome confounding. To address this, we develop a mediation analysis framework that accounts for such confounding within a linear structural equation model with parallel mediators. Specifically, we introduce a pseudo proxy variable to capture unmeasured confounding, allowing us to identify causal parameters. Leveraging this proxy, we propose a partially penalized method to identify mediators that significantly affect the outcome. The resultant estimates are consistent, and the estimates of nonzero parameters are asymptotically normal. Motivated by these results, we further introduce a procedure that can consistently select active mediation pathways with large probability. Simulation studies demonstrate the superior performance of the proposed approach. Finally, we apply our approach to genomic data, identifying gene expressions that potentially mediate the impact of a genetic variant on mouse obesity.

stat.ME↗

Project Imaging-X: A Survey of 1000+ Open-Access Medical Imaging Datasets for Foundation Model Development

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling of such medical datasets are highly challenging due to the reliance on clinical expertise and strict ethical and privacy constraints, resulting in a scarcity of large-scale unified medical datasets and hindering the development of powerful medical foundation models. In this work, we present the largest survey to date of medical image datasets, covering over 1,000 open-access datasets with a systematic catalog of their modalities, tasks, anatomies, annotations, limitations, and potential for integration. Our analysis exposes a landscape that is modest in scale, fragmented across narrowly scoped tasks, and unevenly distributed across organs and modalities, which in turn limits the utility of existing medical image datasets for developing versatile and robust medical foundation models. To turn fragmentation into scale, we propose a metadata-driven fusion paradigm (MDFP) that integrates public datasets with shared modalities or tasks, thereby transforming multiple small data silos into larger, more coherent resources. Building on MDFP, we release an interactive discovery portal that enables end-to-end, automated medical image dataset integration, and compile all surveyed datasets into a unified, structured table that clearly summarizes their key characteristics and provides reference links, offering the community an accessible and comprehensive repository. By charting the current terrain and offering a principled path to dataset consolidation, our survey provides a practical roadmap for scaling medical imaging corpora, supporting faster data discovery, more principled dataset creation, and more capable medical foundation models.

cs.CV↗

Berezinskii-Kosterlitz-Thouless Quantum Supercriticality in XXZ Heisenberg Spin Chain

Quantum fluctuations can give rise to a singular quantum critical point (QCP) in the ground state, whose influence extends to finite temperatures, forming a quantum critical regime (QCR). Recently, it has been shown that in the quantum Ising model, the symmetry-breaking, longitudinal field can induce a quantum supercritical regime (QSR) emanating from the QCP, which hosts a universally enhanced quantum supercritical magnetocaloric effect (MCE). In this paper, we show that the QSR also emerges in the spin-1/2 XXZ model, in both the form of Ising and Berezinskii-Kosterlitz-Thouless (BKT) supercriticality. Using ground-state and finite-temperature tensor-network methods, we investigate quantum supercritical phenomena near a BKT QCP. We reveal a quantum supercritical crossover scaling $T \propto h^{2/3}$ and a Grüneisen ratio scaling $Γ_h \propto T^{-3/2}$ for the BKT QCP, which differ from the corresponding Ising supercritical scalings. Nevertheless, we find that the scaling function $ϕ_Γ(x)$ of the singular Grüneisen ratio for both BKT and Ising cases can be approximately described by the same expression $ϕ_Γ(x) \approx x/(1+x^2)$. Our work extends the study of quantum supercritical phenomena from the Ising to the XXZ Heisenberg model, thereby revealing the presence of BKT quantum supercriticality and broadening the scope of quantum supercritical physics.

cond-mat.str-el↗