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Weijie Ma

Publications and source records attributed to Weijie Ma.

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LynnReal-Omni: Native multi-modal Video Generation for Agentic Visual Workflows

Video diffusion models are stochastic and hard to control: precise content often requires repeated sampling without guaranteed success, and long-horizon scenes drift in appearance, interactions, and temporal coherence. Agentic visual creation provides explicit references, editable 3D scenes, or executable game states for stable control, but does not by itself guarantee high object or character fidelity. Combining the two can enable stable, high-quality generation. To realize this combination, we present LynnReal-Omni, a native multimodal video generation framework built on a 32B shared multimodal diffusion transformer that unifies text-to-video, image-conditioned generation, reference-guided generation, structural control, editing, degraded video restoration, and long-video generation. It accepts heterogeneous visual inputs, including appearance references, editable 3D renders, and game recordings, allowing agents to compose visual conditions within a unified model. We also train a dedicated 27B Flash shared multimodal diffusion transformer for real-time rendering. We build a systematic data pipeline for video cleaning, subject association, multimodal annotation, and aligned control construction, yielding a curated corpus of multi-shot audiovisual segments, and introduce MSAVP, a 100-prompt, 20-metric evaluation design that separates instruction following, generating plausibility, visual quality, temporal behavior, and audio coordination. LynnReal-Omni-Flash further reduces inference cost through model and decoding acceleration, including a lightweight VAE decoder; on one H100, warm generation and decoding of a 22-frame 540p video take 843 ms with LynnReal-Omni and 377 ms with Flash. These results provide a foundation for real-time streaming video generation, making LynnReal-Omni a unified, controllable, and efficient basis for agentic visual creation.

cs.CV

AI Can Learn Scientific Taste

Scientific discovery depends on expert judgement and foresight, which we call scientific taste: the ability to judge and propose research ideas with the potential for long-term scientific impact. Scientific taste is largely concentrated among highly experienced researchers, whose expertise is usually limited to a few specialised fields. If AI could learn scientific taste, it could reduce reliance on human experts and accelerate scientific discovery. Whether AI can learn this ability remains an open question. We introduce Reinforcement Learning from Community Feedback (RLCF) to learn judgement and ideation. Scientific Judge learns from community feedback, such as citations. Scientific Thinker learns to propose research ideas with high potential impact. Experiments show that Scientific Judge outperforms strong LLM baselines and that learned judgement generalises to future-year papers, other community metrics, and unseen fields. Furthermore, Scientific Thinker proposes research ideas with higher potential impact than those proposed by baselines. These results suggest that AI can learn scientific taste, marking an important step towards AI systems that could help accelerate scientific discovery.

cs.CL

AdaThink-Med: Optimizing Inference-Time Compute for Medical Reasoning via Uncertainty Quantification

Extended Chain-of-Thought (CoT) reasoning has significantly bolstered the capabilities of medical large language models (LLMs). However, current models exhibit static computational expenditure, applying lengthy reasoning processes indiscriminately to both simple queries and complex diagnostic cases. This inefficiency is particularly prohibitive in real-world healthcare, where clinical scenarios range from time-sensitive emergencies requiring rapid response to intricate pathologies demanding deep analysis. To address this, we propose \textbf{AdaThink-Med}\footnote{Code available at https://github.com/shaohao011/AdaThinkMed}, an end-to-end framework for adaptive reasoning via uncertainty-guided length calibration. Although the underlying mechanism is generalizable, we demonstrate its critical value in the medical domain, where balancing inference latency with diagnostic precision is paramount. AdaThink-Med leverages entropy-based uncertainty estimation within reinforcement fine-tuning to dynamically shape reward signals: it penalizes verbosity for high-confidence correct answers (e.g., straightforward knowledge retrieval) while incentivizing extended exploration for uncertain or ambiguous scenarios. Across six medical benchmarks, AdaThink-Med reduces inference token consumption by \textbf{4.7$\times$ to 6.4$\times$} on Qwen and Llama architectures, respectively, with minimal performance trade-offs. Notably, our reward design naturally produces distinct ``non-thinking'' and ``thinking'' modes within a single model, enabling efficient allocation of computational resources without any external router or classifier.

cs.CL

BiWM: Advancing Open-Source Interactive Video World Models with Bidirectional Autoregression

Interactive video world models commonly convert bidirectional video generators into causal autoregressive systems through control fine-tuning, autoregressive training, causal initialization, and few-step distillation. This pipeline is costly, while frozen causal histories accumulate errors that degrade long-horizon fidelity and controllability. We present BiWM, the first open-source full-stack training framework for bidirectional autoregressive video world models. BiWM retains full attention within each generated chunk and requires only two stages: camera/action-control fine-tuning and few-step Distribution Matching Distillation (DMD). Both stages converge within a few hundred optimizer steps on 8 H200 GPUs. The framework supports Wan2.1-T2V-1.3B, Wan2.2-TI2V-5B, HunyuanVideo-1.5-TI2V-8B, and LTX-2.3-22B, together with real-world camera control, pluggable long-history compression, and optional low-bit deployment. Supervised and forward-KL anchors mitigate DMD mode collapse and preserve scene dynamics. BiWM provides a compact, reproducible path from pretrained bidirectional video models to interactive, controllable, and efficient world models.

cs.CV

Evidence-Grounded AI for Musculoskeletal Care

Musculoskeletal diseases are among the leading causes of disability and drive the greatest global need for rehabilitation. Because recovery, remodelling and degeneration of bones, joints and related tissues unfold over months to years, care requires longitudinal management rather than isolated decisions. Clinicians must repeatedly integrate evolving patient evidence, medical knowledge and stage-specific functional goals, yet evidence is often fragmented across visits, departments and hospital systems, disrupting continuous, individualised management. Here we report OrthoPilot, a clinical artificial intelligence (AI) system powered by a large language model (LLM) that integrates hospital data streams with authoritative external knowledge for continuous musculoskeletal care. It autonomously retrieves real-time imaging, laboratory, pathology and order data and translates evolving patient states into evidence-based decisions from admission diagnosis through rehabilitation planning. We established a specialist-validated benchmark from real-world electronic health records (EHRs) spanning 1,000 disease codes. In a full-pathway reader study against 81 orthopaedic physicians, OrthoPilot outperformed experts with 25 years of experience in diagnostic reasoning, clinical decision-making and management planning. This advantage generalised across 60 external clinical centres, where OrthoPilot surpassed all evaluated intelligent systems. In a prospective physician decision-making study of 1,870 complex cases, OrthoPilot improved full-chain management success by 10.6%. In a randomised deployment involving 8,240 inpatients, integration into routine care increased cumulative cases per bed by 9.7% and improved patient-reported access to health information. These results move clinical AI from predicting isolated events toward executing longitudinal management across complete musculoskeletal care pathways.

cs.AI

Towards Precision Therapy in Hepatocellular Carcinoma: A Clinical-Reasoning LLM for Risk Stratification and Treatment Guidance

Hepatocellular carcinoma (HCC) is a common malignancy and a leading cause of cancer-related mortality. Current guidelines and staging systems provide coarse categories, but often miss within-stage heterogeneity and the clinical context in electronic medical records (EMRs). We present HCC-STAR (Hepatocellular Carcinoma Staging, Treatment And pRognosis), a clinically aligned large language model that reads routine EMR narratives and jointly outputs risk score-based staging, ranked guideline-consistent treatments with evidence-based rationales, and individualized survival estimates. We curated about 30,000 HCC cases from SEER and expanded them into EMR-style narrative training data using a clinician-validated, prompt-based augmentation workflow. On this corpus, we developed a knowledge-aligned reasoning framework optimized with a step-verifiable composite reward, moving beyond text-level memorization of clinical guidelines. In a multi-center cohort of 6,668 patients from 12 hospitals in China, HCC-STAR achieved state-of-the-art performance in treatment recommendation and risk stratification compared with clinical guidelines and competitive models, including GPT-5 and Gemini-2.5 Pro. Hypothetical overall-survival analysis showed a median survival of 51 months under adherence to HCC-STAR recommendations, compared with 29 and 32 months under BCLC and CNLC. In clinician-centric evaluations, blinded hepatobiliary specialists rated HCC-STAR's reasoning and evidence-based justifications as trustworthy. The model surpassed resident and attending physicians in treatment accuracy and helped physicians make more accurate decisions faster when used as an assistant. These findings support HCC-STAR as a reliable and verifiable decision-support system for risk stratification and precision therapy in HCC.

cs.AI

ResearchClawBench: A Benchmark for End-to-End Autonomous Scientific Research

AI coding agents are increasingly used for scientific work, but their end-to-end autonomous research capability remains difficult to verify. We present ResearchClawBench, a benchmark for evaluating autonomous scientific research across 40 tasks from 10 scientific domains. Each task is grounded in a real published paper, provides related literature and raw data, and hides the target paper during evaluation. Expert-curated multimodal rubrics decompose the target scientific artifacts into weighted criteria, enabling evaluation of target-paper-level re-discovery while leaving room for new discovery. We evaluate seven autonomous research (auto-research) agents under a unified protocol and seventeen native LLMs through the lightweight ResearchHarness. Current systems remain far from reliable re-discovery: the strongest autonomous agent, Claude Code, averages 21.5, and the strongest ResearchHarness LLM, Claude-Opus-4.7, averages 20.7, with an LLM frontier mean of only 26.5. Error analysis shows that failures concentrate in experimental protocol mismatch, evidence mismatch, and missing scientific core. ResearchClawBench provides a reproducible evaluation frontier for measuring progress toward autonomous scientific research.

cs.LG

Project Imaging-X: A Survey of 1000+ Open-Access Medical Imaging Datasets for Foundation Model Development

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling of such medical datasets are highly challenging due to the reliance on clinical expertise and strict ethical and privacy constraints, resulting in a scarcity of large-scale unified medical datasets and hindering the development of powerful medical foundation models. In this work, we present the largest survey to date of medical image datasets, covering over 1,000 open-access datasets with a systematic catalog of their modalities, tasks, anatomies, annotations, limitations, and potential for integration. Our analysis exposes a landscape that is modest in scale, fragmented across narrowly scoped tasks, and unevenly distributed across organs and modalities, which in turn limits the utility of existing medical image datasets for developing versatile and robust medical foundation models. To turn fragmentation into scale, we propose a metadata-driven fusion paradigm (MDFP) that integrates public datasets with shared modalities or tasks, thereby transforming multiple small data silos into larger, more coherent resources. Building on MDFP, we release an interactive discovery portal that enables end-to-end, automated medical image dataset integration, and compile all surveyed datasets into a unified, structured table that clearly summarizes their key characteristics and provides reference links, offering the community an accessible and comprehensive repository. By charting the current terrain and offering a principled path to dataset consolidation, our survey provides a practical roadmap for scaling medical imaging corpora, supporting faster data discovery, more principled dataset creation, and more capable medical foundation models.

cs.CV

Cross-Modality Learning for Predicting IHC Biomarkers from H&E-Stained Whole-Slide Images

Hematoxylin and Eosin (H&E) staining is a cornerstone of pathological analysis, offering reliable visualization of cellular morphology and tissue architecture for cancer diagnosis, subtyping, and grading. Immunohistochemistry (IHC) staining provides molecular insights by detecting specific proteins within tissues, enhancing diagnostic accuracy, and improving treatment planning. However, IHC staining is costly, time-consuming, and resource-intensive, requiring specialized expertise. To address these limitations, this study proposes HistoStainAlign, a novel deep learning framework that predicts IHC staining patterns directly from H&E whole-slide images (WSIs) by learning joint representations of morphological and molecular features. The framework integrates paired H&E and IHC embeddings through a contrastive training strategy, capturing complementary features across staining modalities without patch-level annotations or tissue registration. The model was evaluated on gastrointestinal and lung tissue WSIs with three commonly used IHC stains: P53, PD-L1, and Ki-67. HistoStainAlign achieved weighted F1 scores of 0.735 [95% Confidence Interval (CI): 0.670-0.799], 0.830 [95% CI: 0.772-0.886], and 0.723 [95% CI: 0.607-0.836], respectively for these three IHC stains. Embedding analyses demonstrated the robustness of the contrastive alignment in capturing meaningful cross-stain relationships. Comparisons with a baseline model further highlight the advantage of incorporating contrastive learning for improved stain pattern prediction. This study demonstrates the potential of computational approaches to serve as a pre-screening tool, helping prioritize cases for IHC staining and improving workflow efficiency.

eess.IV

Improving Medical Reasoning with Curriculum-Aware Reinforcement Learning

Recent advances in reinforcement learning with verifiable, rule-based rewards have greatly enhanced the reasoning capabilities and out-of-distribution generalization of VLMs/LLMs, obviating the need for manually crafted reasoning chains. Despite these promising developments in the general domain, their translation to medical imaging remains limited. Current medical reinforcement fine-tuning (RFT) methods predominantly focus on close-ended VQA, thereby restricting the model's ability to engage in world knowledge retrieval and flexible task adaptation. More critically, these methods fall short of addressing the critical clinical demand for open-ended, reasoning-intensive decision-making. To bridge this gap, we introduce \textbf{MedCCO}, the first multimodal reinforcement learning framework tailored for medical VQA that unifies close-ended and open-ended data within a curriculum-driven RFT paradigm. Specifically, MedCCO is initially fine-tuned on a diverse set of close-ended medical VQA tasks to establish domain-grounded reasoning capabilities, and is then progressively adapted to open-ended tasks to foster deeper knowledge enhancement and clinical interpretability. We validate MedCCO across eight challenging medical VQA benchmarks, spanning both close-ended and open-ended settings. Experimental results show that MedCCO consistently enhances performance and generalization, achieving a 11.4\% accuracy gain across three in-domain tasks, and a 5.7\% improvement on five out-of-domain benchmarks. These findings highlight the promise of curriculum-guided RL in advancing robust, clinically-relevant reasoning in medical multimodal language models.

cs.AI

LSSInst: Improving Geometric Modeling in LSS-Based BEV Perception with Instance Representation

With the attention gained by camera-only 3D object detection in autonomous driving, methods based on Bird-Eye-View (BEV) representation especially derived from the forward view transformation paradigm, i.e., lift-splat-shoot (LSS), have recently seen significant progress. The BEV representation formulated by the frustum based on depth distribution prediction is ideal for learning the road structure and scene layout from multi-view images. However, to retain computational efficiency, the compressed BEV representation such as in resolution and axis is inevitably weak in retaining the individual geometric details, undermining the methodological generality and applicability. With this in mind, to compensate for the missing details and utilize multi-view geometry constraints, we propose LSSInst, a two-stage object detector incorporating BEV and instance representations in tandem. The proposed detector exploits fine-grained pixel-level features that can be flexibly integrated into existing LSS-based BEV networks. Having said that, due to the inherent gap between two representation spaces, we design the instance adaptor for the BEV-to-instance semantic coherence rather than pass the proposal naively. Extensive experiments demonstrated that our proposed framework is of excellent generalization ability and performance, which boosts the performances of modern LSS-based BEV perception methods without bells and whistles and outperforms current LSS-based state-of-the-art works on the large-scale nuScenes benchmark.

cs.CV

CrossFusion: Interleaving Cross-modal Complementation for Noise-resistant 3D Object Detection

The combination of LiDAR and camera modalities is proven to be necessary and typical for 3D object detection according to recent studies. Existing fusion strategies tend to overly rely on the LiDAR modal in essence, which exploits the abundant semantics from the camera sensor insufficiently. However, existing methods cannot rely on information from other modalities because the corruption of LiDAR features results in a large domain gap. Following this, we propose CrossFusion, a more robust and noise-resistant scheme that makes full use of the camera and LiDAR features with the designed cross-modal complementation strategy. Extensive experiments we conducted show that our method not only outperforms the state-of-the-art methods under the setting without introducing an extra depth estimation network but also demonstrates our model's noise resistance without re-training for the specific malfunction scenarios by increasing 5.2\% mAP and 2.4\% NDS.

cs.CV

Toward Clinically Assisted Colorectal Polyp Recognition via Structured Cross-modal Representation Consistency

The colorectal polyps classification is a critical clinical examination. To improve the classification accuracy, most computer-aided diagnosis algorithms recognize colorectal polyps by adopting Narrow-Band Imaging (NBI). However, the NBI usually suffers from missing utilization in real clinic scenarios since the acquisition of this specific image requires manual switching of the light mode when polyps have been detected by using White-Light (WL) images. To avoid the above situation, we propose a novel method to directly achieve accurate white-light colonoscopy image classification by conducting structured cross-modal representation consistency. In practice, a pair of multi-modal images, i.e. NBI and WL, are fed into a shared Transformer to extract hierarchical feature representations. Then a novel designed Spatial Attention Module (SAM) is adopted to calculate the similarities between the class token and patch tokens %from multi-levels for a specific modality image. By aligning the class tokens and spatial attention maps of paired NBI and WL images at different levels, the Transformer achieves the ability to keep both global and local representation consistency for the above two modalities. Extensive experimental results illustrate the proposed method outperforms the recent studies with a margin, realizing multi-modal prediction with a single Transformer while greatly improving the classification accuracy when only with WL images.

cs.CV