arXiv subjects

Weiming Chen

Publications and source records attributed to Weiming Chen.

12 recordsLinked to original sources

arXiv2026

DeCo-MIL: Debiased Counterfactual Reasoning for Long-Tailed Whole Slide Image Analysis

Multiple instance learning (MIL) is widely used for weakly supervised whole slide image (WSI) analysis. However, under long-tailed distributions, MIL-based WSI analysis faces a nested dual long-tail: an inter-slide class long tail and an intra-slide long tail of instance-level discriminative evidence. The two long tails are coupled: tail classes have few training slides, while their limited diagnostic evidence is concentrated in a few patches and obscured by abundant within-bag redundancy. This coupling biases models toward head classes and degrades rare-class recognition. To address this, we propose DeCo-MIL for long-tailed WSI analysis, which jointly alleviates the nested dual long-tail through frequency-debiased counterfactual reasoning. For the inner long tail, DeCo-MIL clusters patches into tissue-morphology anchors, replaces each anchor with its matched normal prototype to perform a counterfactual intervention, and estimates its counterfactual contribution to the ground-truth class using class-frequency-corrected predictions. These contributions guide redundancy masking to preserve scarce discriminative instances. For the outer long tail, DeCo-MIL constructs anchor-stratified pseudo-bags from redundancy-reduced bags and combines tail-aware oversampling with consistency regularization, increasing effective supervision for tail classes while preserving tissue-morphology composition. Extensive experiments on three long-tailed WSI benchmarks demonstrate that DeCo-MIL achieves state-of-the-art performance in both tail-class recognition and overall classification.

cs.CV↗

arXiv2026

In-Loop Model Adaptation with Coupled Latent-Noise Guidance for High-Fidelity Subject-Driven Text-to-Image Generation

Text-to-image diffusion models have achieved remarkable success in generating high-quality images from a given text prompt. Subject-driven generation aims to synthesize customized images to mimic the appearance of subjects in given reference images within different visual contexts specified by the text prompts. The central challenge here is that, when the reference image changes, the diffusion model cannot efficiently adapt to different visual contexts while consistently maintaining the subject identity. Existing methods either train the model with a large domain-specific dataset or fine-tune the model using the reference image for hundreds of iterations before actual image generation. In this work, we explore a new approach, called \textit{In-Loop Model Adaptation} (IMA), which adapts the core diffusion model at each generation step during the actual process of image generation, without being trained on the reference image before the generation process. To this end, we establish a DDIM inversion chain that maps the reference image to a sequence of latent, as well as a text-to-image generation chain which generates the image from the text prompt only. We then introduce a masked latent consistency loss and a noise regularization loss to characterize the latent-noise difference between the diffusion model and these two chains at each generation step. This coupled latent-noise loss is used to guide the in-loop model adaptation to preserve the subject identity specified by the reference image while maintaining accurate alignment with the text prompt, resulting in high-fidelity text-to-image generation. Our extensive experiments demonstrate that our proposed IMA method significantly improves the performance of subject-driven text-to-image generation.

cs.CV↗

arXiv2026

SlideCheck: Guiding Self-Supervised Pretraining of Pathology Foundation Models via Dataset Distributions

Pathology foundation models are pretrained on large streams of WSI-derived patches, while supervision during data construction is often slide-level, sparse, or heterogeneous. This mismatch makes it difficult to understand and control which biological patterns enter the pretraining data. We propose SlideCheck, a lightweight pretraining data guidance tool built on frozen pathology foundation model patch features. Rather than serving as a standalone patch diagnostic model, SlideCheck provides explicit abnormality and malignancy scores for organizing, filtering, and auditing pathology pretraining data. SlideCheck uses a dual-head MLP to separately model broad abnormal morphology and malignant evidence. A regularized feature-space scorer provides a supervised anchor for patch-level evidence estimation, while score-attention agreement combines patch scores with WSI-level MIL attention to mine high-confidence pseudo labels. The same scores are then used to construct broad-positive ViT pretraining subsets, where a patch is selected if either abnormality or malignancy evidence exceeds a threshold. Experiments show that SlideCheck-defined data distributions influence the downstream behavior of self-supervised ViT pretraining, indicating that biological composition is an important controllable factor in pathology foundation model development. Curated subsets can approach full-data performance, suggesting that explicitly scored patch pools may support more efficient and auditable pretraining data construction. These findings position SlideCheck as a data guidance and auditing layer for transforming large, undifferentiated patch pools into controllable and reusable pretraining datasets.

cs.CV↗

arXiv2026

Beyond ViT Tokens: Masked-Diffusion Pretrained Convolutional Pathology Foundation Model for Cell-Level Dense Prediction

Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely on patch tokenization, which can disrupt spatial continuity and weaken local morphological details needed for cell-level prediction. To address this, we propose Masked-Diffusion Convolutional Foundation Models, termed ConvNeXt Masked-Diffusion (CMD), a self-supervised convolutional generative pretraining framework for dense pathology representation learning. CMD uses a fully convolutional ConvNeXt-UNet backbone, performs masked-diffusion pretraining in pixel space, and incorporates frozen pathology foundation model features through adaptive normalization. Experimental results demonstrate that CMD consistently outperforms existing ViT-based pathology foundation models and even surpasses state-of-the-art end-to-end segmentation methods while fine-tuning only a small number of task-specific parameters across multiple pathology dense prediction tasks. The advantage is particularly pronounced under limited annotation settings, where CMD exhibits stronger robustness and generalization ability. Our findings suggest that purely convolutional architectures can also serve as competitive pathology foundation models for cell-level dense prediction, achieving leading performance within the current ViT-dominated paradigm and providing a scalable, high-performance solution that better preserves histological structural priors for fine-grained pathology understanding.

cs.CV↗

arXiv2026

Is Class Signal Clustered or Routed in Task-Induced Implicit Neural Representation Weight Spaces?

Implicit neural representations (INRs) encode images as neural-network weights, making image classification a problem of weight-space classifiability. A natural geometric hypothesis is that classifier feedback should make image-specific weights cluster by class in the shared-anchor coordinate. We test this hypothesis in the SIREN-based Meta Weight Transformer (MWT) regime, where end-to-end training meta-learns a shared initialization and inner-loop update schedule for fitting image-specific SIRENs. We find that this prediction fails. Exposed weight-space geometry and supervised clustering pressure do not reliably track trained-reader accuracy; clustering can even make local neighborhoods more class-consistent while making the trained reader worse. Crucially, the reader constructs rather than inherits class-aligned geometry: token-flow diagnostics show that class-aligned neighborhoods become strongly predictive of trained-reader accuracy only after late reader interactions, not in the input coordinate. We further identify the native SIREN bias column in the augmented weight token as a low-dimensional, sample-dependent causal readout route for the trained reader; targeted controls rule out generic scalar-column and marginal-distribution artifacts. The diagnosis motivates interventions that strengthen reader routing, add an explicit bias route, or use denser inner-loop fitting; under the lane-specific training conventions used here, route-directed variants often outperform the shared-anchor baseline but interact non-additively. Task-induced INR weights are classifiable not because they form raw geometric clusters, but because their class signal is routed through the reader.

cs.CV↗

arXiv2026

A Digital Pathology Resource for Liver Cancer Quantification with Datasets, Benchmarks, and Tools

Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment selection and patient survival, and pathological examination remains the gold standard for liver cancer diagnosis. Identifying diverse tissue components and pathological subtypes on histopathology slides is crucial for estimating postoperative recurrence risk and overall prognosis. However, most publicly available resources are still provided at the whole-slide image (WSI) level, and well-annotated datasets for fine-grained tissue component identification in liver cancer are scarce, which hinders reproducible model development and the deployment of quantitative analysis tools. To address this gap, we release HepatoBench, a patch-level image database for liver cancer with annotations for seven key tissue categories. Based on HepatoBench, we train and open-source a deep learning classification model as a tissue recognition tool. Furthermore, we train a WSI-level tumor/non-tumor segmentation model to automatically localize lesion regions across entire slides. By integrating the patch-level tissue classifier with the WSI-level segmentation model, we build HepatoQuant, an end-to-end, disease-specific regional quantification tool for liver cancer, enabling a unified workflow from WSIs to tissue composition parsing and quantitative statistics. We also open-source HepatoBench, the benchmarking protocol, and supporting tools, providing a solid foundation for automated regional quantification and fair method comparison in liver cancer pathology.

cs.CV↗

arXiv2026

Latent Bias Alignment for High-Fidelity Diffusion Inversion in Real-World Image Reconstruction and Manipulation

Recent research has shown that text-to-image diffusion models are capable of generating high-quality images guided by text prompts. But can they be used to generate or approximate real-world images from the seed noise? This is known as the diffusion inversion problem, which serves as a fundamental building block for bridging diffusion models and real-world scenarios. However, existing diffusion inversion methods often suffer from low reconstruction quality or weak robustness. Two major challenges need to be carefully addressed: (1) the misalignment between the inversion and generation trajectories during the diffusion process, and (2) the mismatch between the diffusion inversion process and the VQ autoencoder (VQAE) reconstruction. To address these challenges, we introduce a latent bias vector at each inversion step, which is learned to reduce the misalignment between inversion and generation trajectories. We refer to this strategy as Latent Bias Optimization (LBO). Furthermore, we perform an approximate joint optimization of the diffusion inversion and VQAE reconstruction processes by learning to adjust the image latent representation, which serves as the connecting interface between them. We refer to this technique as Image Latent Boosting (ILB). Extensive experimental results demonstrate that the proposed method significantly improves the image reconstruction quality of the diffusion model, as well as the performance of downstream tasks, including image editing and rare concept generation.

cs.CV↗

arXiv2026

To What Extent Do Token-Level Representations from Pathology Foundation Models Improve Dense Prediction?

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation), practical deployment still lacks a clear, reproducible understanding of how different PFMs behave across datasets and how adaptation choices affect performance and stability. We present PFM-DenseBench, a large-scale benchmark for dense pathology prediction, evaluating 17 PFMs across 18 public segmentation datasets. Under a unified protocol, we systematically assess PFMs with multiple adaptation and fine-tuning strategies, and derive insightful, practice-oriented findings on when and why different PFMs and tuning choices succeed or fail across heterogeneous datasets. We release containers, configs, and dataset cards to enable reproducible evaluation and informed PFM selection for real-world dense pathology tasks. Project Website: https://m4a1tastegood.github.io/PFM-DenseBench

eess.IV↗

arXiv2025

Generative Semantic Coding for Ultra-Low Bitrate Visual Communication and Analysis

We consider the problem of ultra-low bit rate visual communication for remote vision analysis, human interactions and control in challenging scenarios with very low communication bandwidth, such as deep space exploration, battlefield intelligence, and robot navigation in complex environments. In this paper, we ask the following important question: can we accurately reconstruct the visual scene using only a very small portion of the bit rate in existing coding methods while not sacrificing the accuracy of vision analysis and performance of human interactions? Existing text-to-image generation models offer a new approach for ultra-low bitrate image description. However, they can only achieve a semantic-level approximation of the visual scene, which is far insufficient for the purpose of visual communication and remote vision analysis and human interactions. To address this important issue, we propose to seamlessly integrate image generation with deep image compression, using joint text and coding latent to guide the rectified flow models for precise generation of the visual scene. The semantic text description and coding latent are both encoded and transmitted to the decoder at a very small bit rate. Experimental results demonstrate that our method can achieve the same image reconstruction quality and vision analysis accuracy as existing methods while using much less bandwidth. The code will be released upon paper acceptance.

cs.CV↗

arXiv2025

Understanding the Implicit User Intention via Reasoning with Large Language Model for Image Editing

Existing image editing methods can handle simple editing instructions very well. To deal with complex editing instructions, they often need to jointly fine-tune the large language models (LLMs) and diffusion models (DMs), which involves very high computational complexity and training cost. To address this issue, we propose a new method, called \textbf{C}omplex \textbf{I}mage \textbf{E}diting via \textbf{L}LM \textbf{R}easoning (CIELR), which converts a complex user instruction into a set of simple and explicit editing actions, eliminating the need for jointly fine-tuning the large language models and diffusion models. Specifically, we first construct a structured semantic representation of the input image using foundation models. Then, we introduce an iterative update mechanism that can progressively refine this representation, obtaining a fine-grained visual representation of the image scene. This allows us to perform complex and flexible image editing tasks. Extensive experiments on the SmartEdit Reasoning Scenario Set show that our method surpasses the previous state-of-the-art by 9.955 dB in PSNR, indicating its superior preservation of regions that should remain consistent. Due to the limited number of samples of public datasets of complex image editing with reasoning, we construct a benchmark named CIEBench, containing 86 image samples, together with a metric specifically for reasoning-based image editing. CIELR also outperforms previous methods on this benchmark. The code and dataset are available at \href{https://github.com/Jia-shao/Reasoning-Editing}{https://github.com/Jia-shao/Reasoning-Editing}.

cs.CV↗

arXiv2025

Runge-Kutta Approximation and Decoupled Attention for Rectified Flow Inversion and Semantic Editing

Rectified flow (RF) models have recently demonstrated superior generative performance compared to DDIM-based diffusion models. However, in real-world applications, they suffer from two major challenges: (1) low inversion accuracy that hinders the consistency with the source image, and (2) entangled multimodal attention in diffusion transformers, which hinders precise attention control. To address the first challenge, we propose an efficient high-order inversion method for rectified flow models based on the Runge-Kutta solver of differential equations. To tackle the second challenge, we introduce Decoupled Diffusion Transformer Attention (DDTA), a novel mechanism that disentangles text and image attention inside the multimodal diffusion transformers, enabling more precise semantic control. Extensive experiments on image reconstruction and text-guided editing tasks demonstrate that our method achieves state-of-the-art performance in terms of fidelity and editability. Code is available at https://github.com/wmchen/RKSovler_DDTA.

cs.CV↗

arXiv2025

LatentEdit: Adaptive Latent Control for Consistent Semantic Editing

Diffusion-based Image Editing has achieved significant success in recent years. However, it remains challenging to achieve high-quality image editing while maintaining the background similarity without sacrificing speed or memory efficiency. In this work, we introduce LatentEdit, an adaptive latent fusion framework that dynamically combines the current latent code with a reference latent code inverted from the source image. By selectively preserving source features in high-similarity, semantically important regions while generating target content in other regions guided by the target prompt, LatentEdit enables fine-grained, controllable editing. Critically, the method requires no internal model modifications or complex attention mechanisms, offering a lightweight, plug-and-play solution compatible with both UNet-based and DiT-based architectures. Extensive experiments on the PIE-Bench dataset demonstrate that our proposed LatentEdit achieves an optimal balance between fidelity and editability, outperforming the state-of-the-art method even in 8-15 steps. Additionally, its inversion-free variant further halves the number of neural function evaluations and eliminates the need for storing any intermediate variables, substantially enhancing real-time deployment efficiency.

cs.GR↗