arXiv subjects

Weizheng Xie

Publications and source records attributed to Weizheng Xie.

7 recordsLinked to original sources

arXiv2026

GlaBoost: A Multimodal Structured Framework for Glaucoma Risk Stratification

Early and accurate glaucoma detection is critical to prevent irreversible vision loss, yet existing AI methods often rely on unimodal inputs and lack interpretability. We present GlaBoost, a multimodal gradient boosting framework that unifies three complementary signals for glaucoma risk prediction: fundus image embeddings from a pretrained convolutional encoder,free-text neuroretinal rim assessments encoded by a transformer-based language model, and structured ophthalmic biomarkers. These modalities are fused into a single representation and classified by an enhanced XGBoost model.On two real-world annotated datasets, GlaBoost consistently outperforms unimodal and generic multimodal baselines. Feature importance analysis highlights the cup-to-disc ratio, rim thinning, and the ISNT rule as the dominant predictors, yielding clinically consistent and interpretable decisions. GlaBoost offers a transparent and scalable foundation for multimodal decision support in ophthalmology.

cs.LG↗

arXiv2025

Automated Glaucoma Report Generation via Dual-Attention Semantic Parallel-LSTM and Multimodal Clinical Data Integration

Generative AI for automated glaucoma diagnostic report generation faces two predominant challenges: content redundancy in narrative outputs and inadequate highlighting of pathologically significant features including optic disc cupping, retinal nerve fiber layer defects, and visual field abnormalities. These limitations primarily stem from current multimodal architectures' insufficient capacity to extract discriminative structural-textural patterns from fundus imaging data while maintaining precise semantic alignment with domain-specific terminology in comprehensive clinical reports. To overcome these constraints, we present the Dual-Attention Semantic Parallel-LSTM Network (DA-SPL), an advanced multimodal generation framework that synergistically processes both fundus imaging and supplementary visual inputs. DA-SPL employs an Encoder-Decoder structure augmented with the novel joint dual-attention mechanism in the encoder for cross-modal feature refinement, the parallelized LSTM decoder architecture for enhanced temporal-semantic consistency, and the specialized label enhancement module for accurate disease-relevant term generation. Rigorous evaluation on standard glaucoma datasets demonstrates DA-SPL's consistent superiority over state-of-the-art models across quantitative metrics. DA-SPL exhibits exceptional capability in extracting subtle pathological indicators from multimodal inputs while generating diagnostically precise reports that exhibit strong concordance with clinical expert annotations.

cs.CE↗

arXiv2025

BioVessel-Net and RetinaMix: Unsupervised Retinal Vessel Segmentation from OCTA Images

Structural changes in retinal blood vessels are critical biomarkers for the onset and progression of glaucoma and other ocular diseases. However, current vessel segmentation approaches largely rely on supervised learning and extensive manual annotations, which are costly, error-prone, and difficult to obtain in optical coherence tomography angiography. Here we present BioVessel-Net, an unsupervised generative framework that integrates vessel biostatistics with adversarial refinement and a radius-guided segmentation strategy. Unlike pixel-based methods, BioVessel-Net directly models vascular structures with biostatistical coherence, achieving accurate and explainable vessel extraction without labeled data or high-performance computing. To support training and evaluation, we introduce RetinaMix, a new benchmark dataset of 2D and 3D OCTA images with high-resolution vessel details from diverse populations. Experimental results demonstrate that BioVessel-Net achieves near-perfect segmentation accuracy across RetinaMix and existing datasets, substantially outperforming state-of-the-art supervised and semi-supervised methods. Together, BioVessel-Net and RetinaMix provide a label-free, computationally efficient, and clinically interpretable solution for retinal vessel analysis, with broad potential for glaucoma monitoring, blood flow modeling, and progression prediction. Code and dataset are available: https://github.com/VikiXie/SatMar8.

cs.CV↗

arXiv2025

Modeling Insider Filing Delays in Financial Markets with an Interpretable XGBoost Framework

Timely disclosure of insider transactions is a cornerstone of market transparency, yet delays in filing remain widespread and challenging to monitor at scale. This study introduces a comprehensive insider filing delay dataset spanning more than four million Form 4 transactions from 2002 to 2025, enriched with annotations on insider roles, governance attributes, and firm-level indicators. Building on these data, we present a hybrid framework that integrates a state-space encoder with an XGBoost classifier to capture temporal trading patterns while retaining interpretability essential for regulatory auditing. The framework consistently outperforms statistical models, deep sequence learners, and large language model baselines, achieving balanced gains in precision, recall, and F1-score. Feature ablation analyses highlight the predictive importance of insider history, spatiotemporal factors, and governance signals, shedding light on the behavioral drivers of both minor oversights and systematic violations. Beyond accuracy, the dataset and framework establish a reproducible benchmark for studying disclosure compliance, offering regulators and researchers transparent tools to strengthen market integrity.

cs.CE↗

arXiv2025

GlaLSTM: A Concurrent LSTM Stream Framework for Glaucoma Detection via Biomarker Mining

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for unraveling glaucoma's underlying mechanisms. In this paper, we propose GlaLSTM, a novel concurrent LSTM stream framework for glaucoma detection, leveraging latent biomarker relationships. Unlike traditional CNN-based models that primarily detect glaucoma from images, GlaLSTM provides deeper interpretability, revealing the key contributing factors and enhancing model transparency. This approach not only improves detection accuracy but also empowers clinicians with actionable insights, facilitating more informed decision-making. Experimental evaluations confirm that GlaLSTM surpasses existing state-of-the-art methods, demonstrating its potential for both advanced biomarker analysis and reliable glaucoma detection.

eess.IV↗

arXiv2025

X-GAN: A Generative AI-Powered Unsupervised Model for Main Vessel Segmentation of Glaucoma Screening

Structural changes in main retinal blood vessels serve as critical biomarkers for the onset and progression of glaucoma. Identifying these vessels is vital for vascular modeling yet highly challenging. This paper proposes X-GAN, a generative AI-powered unsupervised segmentation model designed for extracting main blood vessels from Optical Coherence Tomography Angiography (OCTA) images. The process begins with the Space Colonization Algorithm (SCA) to rapidly generate a skeleton of vessels, featuring their radii. By synergistically integrating the generative adversarial network (GAN) with biostatistical modeling of vessel radii, X-GAN enables a fast reconstruction of both 2D and 3D representations of the vessels. Based on this reconstruction, X-GAN achieves nearly 100\% segmentation accuracy without relying on labeled data or high-performance computing resources. Experimental results confirm X-GAN's superiority in evaluating main vessel segmentation compared to existing deep learning models.

eess.IV↗

arXiv2025

SPH-Net: A Co-Attention Hybrid Model for Accurate Stock Price Prediction

Prediction of stock price movements presents a formidable challenge in financial analytics due to the inherent volatility, non-stationarity, and nonlinear characteristics of market data. This paper introduces SPH-Net (Stock Price Prediction Hybrid Neural Network), an innovative deep learning framework designed to enhance the accuracy of time series forecasting in financial markets. The proposed architecture employs a novel co-attention mechanism that initially processes temporal patterns through a Vision Transformer, followed by refined feature extraction via an attention mechanism, thereby capturing both global and local dependencies in market data. To rigorously evaluate the model's performance, we conduct comprehensive experiments on eight diverse stock datasets: AMD, Ebay, Facebook, FirstService Corp, Tesla, Google, Mondi ADR, and Matador Resources. Each dataset is standardized using six fundamental market indicators: Open, High, Low, Close, Adjusted Close, and Volume, representing a complete set of features for comprehensive market analysis. Experimental results demonstrate that SPH-Net consistently outperforms existing stock prediction models across all evaluation metrics. The model's superior performance stems from its ability to effectively capture complex temporal patterns while maintaining robustness against market noise. By significantly improving prediction accuracy in financial time series analysis, SPH-Net provides valuable decision-support capabilities for investors and financial analysts, potentially enabling more informed investment strategies and risk assessment in volatile market conditions.

cs.CE↗