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Wenbo Zhang

Publications and source records attributed to Wenbo Zhang.

At least 37 records · Page 2Linked to original sources

Universality Reconsidered: Rethinking the Validation of Foundation Models for General-Purpose 3D Medical Segmentation

Foundation models have emerged as a transformative paradigm in 3D medical imaging, with the promise of unified quantitative analysis across diverse targets and imaging modalities. Yet the prevailing conception of universality remains incomplete. Current models are predominantly developed and evaluated on datasets largely concentrated around a limited set of imaging modalities and anatomical regions. In this Perspective, we evaluate representative 3D segmentation foundation models using paired whole-body structural and functional imaging data. Our analysis reveals a substantial gap between benchmark-reported performance and real-world generalization, with marked degradation on previously unseen data and particularly severe failures on functional imaging modalities. These findings suggest that current foundation models remain far from achieving true universality. We argue that progress requires not only scaling models and datasets, but also a reconsideration of how universality is defined and validated, extending evaluation beyond regional structural benchmarks toward whole-body structural and functional imaging. Our observations highlight the need to distinguish benchmark success from genuine clinical generalization. Bridging this gap will be essential for translating foundation models from controlled evaluation settings to real-world medical practice.

cs.CV↗

MOSS Transcribe Diarize Technical Report

Speaker-Attributed, Time-Stamped Transcription (SATS) aims to transcribe what is said and to precisely determine the timing of each speaker, which is particularly valuable for meeting transcription. Existing SATS systems rarely adopt an end-to-end formulation and are further constrained by limited context windows, weak long-range speaker memory, and the inability to output timestamps. To address these limitations, we present MOSS Transcribe Diarize, a unified multimodal large language model that jointly performs Speaker-Attributed, Time-Stamped Transcription in an end-to-end paradigm. Trained on extensive real wild data and equipped with a 128k context window for up to 90-minute inputs, MOSS Transcribe Diarize scales well and generalizes robustly. Across comprehensive evaluations, it outperforms state-of-the-art commercial systems on multiple public and in-house benchmarks.

cs.SD↗

MKGR: Multimodal Knowledge-Graph Representation Learning for Cold-Start Protein-Protein Interaction Prediction

Accurate protein-protein interaction (PPI) prediction is central to functional genomics, disease mechanism discovery, and drug development. A difficult setting arises when candidate interactions include proteins that have no observed PPI edges during training, where models relying on network topology alone often lose useful context. This paper presents \method, a multimodal representation framework for cold-start PPI prediction. \method\ combines region-aware protein sequence encoding with four protein-centered biomedical knowledge graphs, including protein-drug, protein-disease, protein-miRNA, and protein-lncRNA associations. The sequence branch extracts contextual representations from structurally informed sequence regions, while graph attention encoders learn modality-specific protein embeddings from sparse biomedical associations. A bridge reconstruction objective regularizes graph learning by recovering shared protein-entity associations, and a pair-level gating module adaptively integrates sequence and graph evidence for each candidate protein pair. Experiments on two benchmark datasets under novel-old and novel-novel cold-start settings show that \method\ consistently outperforms competitive sequence, network, and knowledge-graph baselines across ACC, F1, AUC, AUPR, and MCC.

cs.LG↗

PolicyTrim: Boosting Intrinsic Policy Efficiency of Vision-Language-Action Models

Vision-Language-Action (VLA) models provide a unified paradigm for robotic manipulation, yet their real-world deployment is often bottlenecked by execution efficiency. While existing efforts predominantly focus on compute-centric efficiency to reduce per-step inference latency, the intrinsic \textbf{policy efficiency} of these models remains largely unexplored. Policy efficiency is fundamentally affected by two factors, namely the effective executable length of predicted action chunks and the total physical steps required to complete a task. These two factors jointly determine the total number of forward inference calls during execution. We observe that current VLA policies struggle with planning unreliability and action redundancy, suffering from severe prediction degradation at the tail of action chunks and tending to generate unnecessarily redundant physical steps. To address this, we propose \textbf{PolicyTrim}, a reinforcement learning-based post-training framework that extends the reliable action chunk length and reduces redundant physical steps. For reliable chunk extension, we employ a dynamic exploration strategy that explicitly rewards the successful completion of longer executable lengths, progressively pushing the trustworthy prediction horizon to its empirical limit. For step efficiency, we design a redundancy-aware reward that directly favors successful task completions with fewer steps while penalizing unreproducible shortcuts, effectively eliminating redundant physical actions. Extensive experiments across three benchmarks and three VLA models demonstrate that PolicyTrim improves action chunk utilization by 3$\times$ and reduces physical execution steps by 51.4\%. Ultimately, our framework delivers up to a 5.83$\times$ end-to-end deployment speedup without compromising task success rates.

cs.CV↗

An Ensembled Latent Factor Model via Differential Evolution and Gradient Descent Optimization

High-dimensional and incomplete (HDI) data are prevalent in many real-world big data scenarios. Latent factor models serve as a common representation learning approach, capable of uncovering informative latent factors from such data. Nevertheless, most existing latent factor models rely solely on gradient descent for optimization, which may lead to insufficient and biased representations, particularly when dealing with heterogeneous HDI data. Thus, this study proposes an Ensembled Latent Factor Model via Differential Evolution and Gradient Descent Optimization (ELFM-DEGDO) with two-fold designed: 1) two diverse latent factor models are independently modeled via differential evolution and gradient descent optimization, respectively, and 2) the two diverse latent factor models are combined via a customized self-adaptive weighting mechanism to effectively fuse their strengths. By leveraging the complementary advantages of both optimization paradigms, ELFM-DEGDO is able to produce more comprehensive and less biased representations for HDI data. Three HDI datasets are tested to show that ELFM-DEGDO consistently performs better than related several latent factor models.

cs.LG↗

TTT-VLA: Test-Time Latent Prompt Optimization for Vision-Language-Action Models

Vision-Language-Action (VLA) models trained on large-scale data have made remarkable progress, but they remain vulnerable to distribution shifts at deployment time. Recent VLA models suggest that prompts can serve as an efficient interface for steering policy behavior, but existing prompt-based steering typically relies on external guidance. This raises a natural question: can test-time training (TTT) for VLA be achieved by optimizing a prompt, so that the steering interface itself can be learned and adapted from interaction? We address this question with TTT-VLA, a test-time training framework based on Latent Prompt Optimization (LPO). During training, the latent prompt is learned with an additional proxy task, providing an extra learned conditioning signal for policy learning. At test time, TTT is performed by collecting interaction data from the current environment and optimizing only the latent prompt on those data using the proxy task's self-supervised signal, without modifying the policy itself. Experiments on SimplerEnv demonstrate that the proposed method consistently improves task success rates in both single- and multi-embodiment settings. Further analysis shows that the gains arise primarily from correcting a small number of critical decisions rather than globally altering policy behavior. These results suggest that LPO provides an effective and practical pathway for deployment-time improvement of foundation manipulation policies.

cs.RO↗

G2LoRA: Gradient Orthogonal Low-Rank Adaptation Framework for Graph Continual Learning on Text-Attributed Graphs

LLM-as-Aligner has emerged as a prevalent pre-training paradigm for Text-Attributed Graphs(TAGS), aligning graph and text modalities into a shared embedding space via CLIP-style contrastive learning. While effective on individual downstream tasks, we observe severe catastrophic forgetting when such models are sequentially fine-tuned on streaming tasks. Although parameter-efficient fine-tuning alleviates forgetting to some extent, it remains insufficient to resolve task interference and ineffective knowledge transfer. In this work, we study graph continual learning for LLM-as-Aligner models on TAGs, with the goal of mitigating interference while promoting positive transfer across tasks. This setting introduces two fundamental challenges: (1) heterogeneous downstream tasks induce shifting optimization objectives, hindering unified fine-tuning; and (2) graph and text encoders exhibit different sensitivities to adaptation, making uncoordinated updates prone to misalignment. To address these challenges, we propose G2LoRA, a continual learning framework for TAGs. G2LoRA unifies node-, link-, and graph-level tasks under a single graph--text alignment objective, and enables consistent optimization across domain/class/task incremental modes. To reduce task interference while encouraging positive transfer, G2LoRA performs category-aware gradient projection in structured subspaces, resolving conflicting updates and enabling conditional backward transfer to balance forward and backward knowledge flow. To further prevent cross-modal drift, G2LoRA introduces gradient magnitude modulation to coordinate update rates between graph and text encoders. Extensive experiments on benchmark datasets demonstrate that G2LoRA consistently outperforms strong baselines across different backbone architectures, achieving superior continual performance and transferability.

cs.LG↗

Trustworthiness in Retrieval-Augmented Generation Systems: A Survey

Retrieval-Augmented Generation (RAG) has quickly grown into a pivotal paradigm in the development of Large Language Models (LLMs). Although existing research mainly emphasizes accuracy and efficiency, the trustworthiness of RAG systems remains insufficiently explored. RAG can improve LLM reliability by grounding responses in external and up-to-date knowledge, reducing hallucinations. However, unreliable retrieval or improper knowledge utilization may still lead to undesirable outputs. To address these concerns, we propose a unified framework, Trust-RAG Compass, that assesses the trustworthiness of RAG systems across six key dimensions: factuality, robustness, fairness, transparency, accountability, and privacy. Within this framework, we provide a thorough review of the existing literature along each dimension. Furthermore, we introduce an evaluation benchmark, TRC Bench (\underline{T}rust-\underline{R}AG \underline{C}ompass \underline{Bench}mark), regarding the six dimensions and conduct comprehensive evaluations for a variety of proprietary and open-source models. Our results shed light on the performance gaps between different types of LLMs across varying dimensions of trustworthiness. Finally, we identify key challenges and promising directions for future research based on our findings. Through this work, we aim to provide a structured foundation for subsequent investigations and practical guidance for developing trustworthy RAG systems in real-world scenarios.

cs.IR↗

The Hardness of Achieving Impact in AI for Social Impact Research: A Ground-Level View of Challenges & Opportunities

AI for Social Impact (AI4SI) is an emergent field harnessing interdisciplinarities between the fields of artificial intelligence (AI), machine learning (ML), and the social sciences to address societal issues aligned with the United Nations Sustainable Development Goals (UN SDGs), such as universal healthcare, climate action, etc. Despite AI4SI's rising popularity, achieving tangible, on-the-ground impact remains a significant challenge. In particular, identifying collaborators open to co-designing and deploying AI4SI-based solutions in real-world settings is often difficult. Thus, many projects stall at the proof-of-concept stage, unable to scale to production-level deployment. Drawing on twenty-six AI4SI researchers' interviews, primarily from academic institutions though also including some industry researchers and practitioners, and the authors' own lived experiences, this paper employs thematic analysis to highlight structural, organizational, communication, collaboration, and operational challenges hindering socially impactful AI4SI deployments. While there are no easy fixes, the authors synthesize best practices and actionable strategies from interviews and personal experiences, positioning this paper as a practical guide for AI4SI researchers and organizations pursuing socially impactful collaborations$^1$. $^1$We note that our findings are most directly applicable to academic research groups in the global north, as governmental, startup, and global south researchers' perspectives are underrepresented in our sample.

cs.HC↗

Reasoning Is Not Free: Robust Adaptive Cost-Efficient Routing for LLM-as-a-Judge

Reasoning-capable large language models (LLMs) have recently been adopted as automated judges, but their benefits and costs in LLM-as-a-Judge settings remain unclear. Through controlled comparisons between reasoning and non-reasoning judges, we show that explicit reasoning substantially improves judgment accuracy on tasks requiring structured verification (e.g., math and coding), while offering limited or even negative gains on simpler evaluations and incurring significantly higher computational cost. These findings motivate that reasoning should be used selectively rather than universally, with awareness of possible distribution shift. We propose a Robust Adaptive Cost-Efficient Routing (RACER), which dynamically selects between reasoning and non-reasoning judges under a fixed budget by formulating routing as a constrained distributionally robust optimization problem. RACER explicitly accounts for distribution shift via a KL-divergence uncertainty set, admits an efficient primal--dual algorithm, and enjoys theoretical guarantees including uniqueness of the optimal policy and linear convergence. Extensive experiments show that RACER achieves superior accuracy--cost trade-offs under distribution shift.

cs.AI↗

Beyond the Singular: Revealing the Value of Multiple Generations in Benchmark Evaluation

Large language models (LLMs) have demonstrated significant utility in real-world applications, exhibiting impressive capabilities in natural language processing and understanding. Benchmark evaluations are crucial for assessing the capabilities of LLMs as they can provide a comprehensive assessment of their strengths and weaknesses. However, current evaluation methods often overlook the inherent randomness of LLMs by employing deterministic generation strategies or relying on a single random sample, resulting in unaccounted sampling variance and unreliable benchmark score estimates. In this paper, we propose a hierarchical statistical model that provides a more comprehensive representation of the benchmarking process by incorporating both benchmark characteristics and LLM randomness. We show that leveraging multiple generations improves the accuracy of estimating the benchmark score and reduces variance. Multiple generations also allow us to define $\mathbb P\left(\text{correct}\right)$, a prompt-level difficulty score based on correct ratios, providing fine-grained insights into individual prompts. Additionally, we create a data map that visualizes difficulty and semantics of prompts, enabling error detection and quality control in benchmark construction.

cs.CL↗

Resource-efficient parallel entanglement generation for multinode quantum networks via time-bin multiplexing

Nonlocal entanglement generation among multiple remote quantum nodes provides a critical foundation for a variety of counterintuitive quantum applications. The exponential loss of photons transmitting over optical fibers sets an upper limit for entangling these quantum nodes. Here, we propose a resource-efficient and parallel protocol for entangling multiple remote quantum nodes via time-bin multiplexing. The transmission of a single photon with qudit-encoding in the time-bin mode enables entangling multiple stationary qubits in parallel, when single photons and individual stationary qubits interfaces are used and photon-state modulations are properly introduced before subsequently impinging the photon into each interface. Our protocol can generate parallel multipartite entanglement among ($N\geq3$) quantum nodes with the dimension of the photonic time bins independent of $N$, exponentially reducing the requirements for the coherence time of the stationary qubits and for the complexity of the photonic modulations. These distinct features make our protocol particularly advantageous for the development of multinode quantum networks.

quant-ph↗

AutoResearchBench: Benchmarking AI Agents on Complex Scientific Literature Discovery

Autonomous scientific research is significantly advanced thanks to the development of AI agents. One key step in this process is finding the right scientific literature, whether to explore existing knowledge for a research problem, or to acquire evidence for verifying assumptions and supporting claims. To assess AI agents' capability in driving this process, we present AutoResearchBench, a dedicated benchmark for autonomous scientific literature discovery. AutoResearchBench consists of two complementary task types: (1) Deep Research, which requires tracking down a specific target paper through a progressive, multi-step probing process, and (2) Wide Research, which requires comprehensively collecting a set of papers satisfying given conditions. Compared to previous benchmarks on agentic web browsing, AutoResearchBench is distinguished along three dimensions: it is research-oriented, calling for in-depth comprehension of scientific concepts; literature-focused, demanding fine-grained utilization of detailed information; and open-ended, involving an unknown number of qualified papers and thus requiring deliberate reasoning and search throughout. These properties make AutoResearchBench uniquely suited for evaluating autonomous research capabilities, and extraordinarily challenging. Even the most powerful LLMs, despite having largely conquered general agentic web-browsing benchmarks such as BrowseComp, achieve only 9.39% accuracy on Deep Research and 9.31% IoU on Wide Research, while many other strong baselines fall below 5%. We publicly release the dataset and evaluation pipeline to facilitate future research in this direction. We publicly release the dataset, evaluation pipeline, and code at https://github.com/CherYou/AutoResearchBench.

cs.AI↗

Bridging the Gap between Learning and Inference for Diffusion-Based Molecule Generation

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain constrained by exposure bias, error accumulation, and suboptimal handling of activity cliffs. Here, we introduce DiffGap, a diffusion-based framework that integrates adaptive sampling and pseudo-molecule estimation to bridge the gap between training objectives and inference dynamics in 3D molecule generation. By dynamically aligning intermediate denoising steps with realistic generation trajectories, DiffGap enables the diffusion model to adapt to input biases in advance during the training phase. A temperature annealing module further controls the aligning strength of the adaptive alignment process, ensuring stable learning of the data distribution. Evaluated on the CrossDocked2020 benchmark, DiffGap outperforms existing methods in docking scores and binding affinity, demonstrating superior fidelity in generating drug-like molecules. Our work establishes a principled approach to harmonize generative training with inference mechanics, offering a robust computational toolkit for accelerating structure-based therapeutic discovery. The source code of DiffGap is available at https://github.com/neusymlab/DiffGap.

cs.LG↗

Learning Where to Embed: Noise-Aware Positional Embedding for Query Retrieval in Small-Object Detection

Transformer-based detectors have advanced small-object detection, but they often remain inefficient and vulnerable to background-induced query noise, which motivates deep decoders to refine low-quality queries. We present HELP (Heatmap-guided Embedding Learning Paradigm), a noise-aware positional-semantic fusion framework that studies where to embed positional information by selectively preserving positional encodings in foreground-salient regions while suppressing background clutter. Within HELP, we introduce Heatmap-guided Positional Embedding (HPE) as the core embedding mechanism and visualize it with a heatbar for interpretable diagnosis and fine-tuning. HPE is integrated into both the encoder and decoder: it guides noise-suppressed feature encoding by injecting heatmap-aware positional encoding, and it enables high-quality query retrieval by filtering background-dominant embeddings via a gradient-based mask filter before decoding. To address feature sparsity in complex small targets, we integrate Linear-Snake Convolution to enrich retrieval-relevant representations. The gradient-based heatmap supervision is used during training only, incurring no additional gradient computation at inference. As a result, our design reduces decoder layers from eight to three and achieves a 59.4% parameter reduction (66.3M vs. 163M) while maintaining consistent accuracy gains under a reduced compute budget across benchmarks. Code Repository: https://github.com/yidimopozhibai/Noise-Suppressed-Query-Retrieval

cs.CV↗

Many Ways to Be Fake: Benchmarking Fake News Detection Under Strategy-Driven AI Generation

Recent advances in large language models (LLMs) have enabled the large-scale generation of highly fluent and deceptive news-like content. While prior work has often treated fake news detection as a binary classification problem, modern fake news increasingly arises through human-AI collaboration, where strategic inaccuracies are embedded within otherwise accurate and credible narratives. These mixed-truth cases represent a realistic and consequential threat, yet they remain underrepresented in existing benchmarks. To address this gap, we introduce MANYFAKE, a synthetic benchmark containing 6,798 fake news articles generated through multiple strategy-driven prompting pipelines that capture many ways fake news can be constructed and refined. Using this benchmark, we evaluate a range of state-of-the-art fake news detectors. Our results show that even advanced reasoning-enabled models approach saturation on fully fabricated stories, but remain brittle when falsehoods are subtle, optimized, and interwoven with accurate information.

cs.CL↗

A Weak-Signal-Aware Framework for Subsurface Defect Detection: Mechanisms for Enhancing Low-SCR Hyperbolic Signatures

Subsurface defect detection via Ground Penetrating Radar is challenged by "weak signals" faint diffraction hyperbolas with low signal-to-clutter ratios, high wavefield similarity, and geometric degradation. Existing lightweight detectors prioritize efficiency over sensitivity, failing to preserve low-frequency structures or decouple heterogeneous clutter. We propose WSA-Net, a framework designed to enhance faint signatures through physical-feature reconstruction. Moving beyond simple parameter reduction, WSA-Net integrates four mechanisms: Signal preservation using partial convolutions; Clutter suppression via heterogeneous grouping attention; Geometric reconstruction to sharpen hyperbolic arcs; Context anchoring to resolve semantic ambiguities. Evaluations on the RTSTdataset show WSA-Net achieves 0.6958 mAP@0.5 and 164 FPS with only 2.412 M parameters. Results prove that signal-centric awareness in lightweight architectures effectively reduces false negatives in infrastructure inspection.

cs.CV↗

LiveWorld: Simulating Out-of-Sight Dynamics in Generative Video World Models

Recent generative video world models aim to simulate visual environment evolution, allowing an observer to interactively explore the scene via camera control. However, they implicitly assume that the world only evolves within the observer's field of view. Once an object leaves the observer's view, its state is "frozen" in memory, and revisiting the same region later often fails to reflect events that should have occurred in the meantime. In this work, we identify and formalize this overlooked limitation as the "out-of-sight dynamics" problem, which impedes video world models from representing a continuously evolving world. To address this issue, we propose LiveWorld, a novel framework that extends video world models to support persistent world evolution. Instead of treating the world as static observational memory, LiveWorld models a persistent global state composed of a static 3D background and dynamic entities that continue evolving even when unobserved. To maintain these unseen dynamics, LiveWorld introduces a monitor-based mechanism that autonomously simulates the temporal progression of active entities and synchronizes their evolved states upon revisiting, ensuring spatially coherent rendering. For evaluation, we further introduce LiveBench, a dedicated benchmark for the task of maintaining out-of-sight dynamics. Extensive experiments show that LiveWorld enables persistent event evolution and long-term scene consistency, bridging the gap between existing 2D observation-based memory and true 4D dynamic world simulation. The baseline and benchmark will be publicly available at https://zichengduan.github.io/LiveWorld/index.html.

cs.CV↗