arXiv subjects

Wenkong Wang

Publications and source records attributed to Wenkong Wang.

5 recordsLinked to original sources

arXiv2026

Knowledge-augmented Agentic AI for Mental Health Medication Information Seeking

Patients increasingly seek medication information online, yet safety knowledge for psychiatric drugs is split between regulatory adverse-event records, which are authoritative but abstract, and patient narratives, which are experience-near but unvalidated. Integrating them without conflating evidence and anecdote is especially consequential in psychiatry, where poorly contextualised information can amplify fear, nocebo responses, and non-adherence. Here we develop a provenance-aware, knowledge-graph-based multi-agent framework unifying 466,525 Reddit posts, 60,782 WebMD reviews, and twenty years of U.S. FDA Adverse Event Reporting System records for nine antidepressants. A large-language-model entity-recognition pipeline benchmarked against physician annotations reached highest F1 scores of 0.969 for medications and 0.973 for conditions. The two community platforms were far more concordant with each other (overlap up to a Jaccard similarity of 0.905) than with regulatory reports, indicating that patient-generated data form a partly independent safety signal. For sertraline, many adverse events appeared in community sources hundreds of days before the corresponding FDA date. A Neo4j knowledge graph grounded in ATC-N, ICD-10, and MedDRA vocabularies preserves provenance, keeping every claim traceable and regulatory facts distinct from patient experience. These results establish source-aware integration as a route to more auditable psychiatric medication information, with usefulness and patient benefit to be tested prospectively.

cs.AI↗

arXiv2026

AIPatient Arena: EHR-grounded evaluation of large language models in end-to-end clinical consultation workflows

Large language models (LLMs) are increasingly considered for use in clinical consultation tasks, yet most medical evaluations remain static, single-turn, or narrowly outcome-based, limiting their ability to reflect the sequential, uncertain, and interactive nature of real-world care. Here, we propose AIPatient Arena, an EHRs-grounded evaluation framework for assessing the clinical utility of LLMs across eight dimensions of clinical competence. The framework integrates EHR data into patient-specific knowledge graphs, enabling multi-turn physician-patient interactions. We applied AIPatient Arena on a primary cohort of 437 patients and two out-of-distribution validation cohorts of 119 and 67 patients. We observe that LLMs performed well in medical interview questioning skills (QS; mean scores, 4.43-4.99/5), ethical and professional conduct (ET; 4.38-4.93/5), and clarity and transparency of clinical explanations (EX; 3.80-4.72/5). Performance was moderate in information integration (II; 3.19-4.21/5) and medication safety and justification (MS; 3.13-3.78/5), but persistent weaknesses were observed in handling of ambiguous patient responses (HR; 2.57-3.32/5), information coverage (IC; 2.08-3.02/5), and diagnostic accuracy and reasoning (Dx; 2.63-3.55/5). Process-based evaluation revealed recurrent interaction failures, including repetitive questioning, omission of past medical history, and inadequate handling of uncertainty. Richer conversational context improved diagnostic reasoning but yielded limited gains in treatment planning. These findings indicate that final-answer accuracy alone is insufficient for evaluating clinical readiness and highlight the importance of assessing how models gather, interpret, and communicate information throughout a consultation. AIPatient Arena provides an EHR-grounded framework for workflow-oriented pre-deployment evaluation of medical LLMs.

cs.CL↗

arXiv2025

Graph Convolutional Long Short-Term Memory Attention Network for Post-Stroke Compensatory Movement Detection Based on Skeleton Data

Most stroke patients experience upper limb motor dysfunction. Compensatory movements are prevalent during rehabilitation training, which is detrimental to patients' long-term recovery. Therefore, detecting compensatory movements is of great significance. In this study, a Graph Convolutional Long Short-Term Memory Attention Network (GCN-LSTM-ATT) based on skeleton data is proposed for the detection of compensatory movements after stroke. Sixteen stroke patients were selected in the research. The skeleton data of the patients performing specific rehabilitation movements were collected using the Kinect depth camera. After data processing, detection models were constructed respectively using the GCN-LSTM-ATT model, the Support Vector Machine(SVM), the K-Nearest Neighbor algorithm(KNN), and the Random Forest(RF). The results show that the detection accuracy of the GCN-LSTM-ATT model reaches 0.8580, which is significantly higher than that of traditional machine learning algorithms. Ablation experiments indicate that each component of the model contributes significantly to the performance improvement. These findings provide a more precise and powerful tool for the detection of compensatory movements after stroke, and are expected to facilitate the optimization of rehabilitation training strategies for stroke patients.

cs.CV↗

arXiv2025

Adaptive Parameter Control Using AAN for Lower Limb Rehabilitation Exoskeletons

Exoskeletons play a crucial role in assisting patients with varying mobility levels during rehabilitation. However, existing control strategies face challenges such as imprecise trajectory tracking, interaction torque oscillations, and limited adaptability to diverse patient conditions. To address these issues, this paper proposes an assist-as-needed (AAN) control algorithm that integrates a human-robot coupling dynamics model, a human torque-momentum observer (HTMO), and an adaptive parameter controller (APC). The algorithm first employs inverse dynamics to compute the joint torques required for the rehabilitation trajectory. The HTMO then estimates the torque exerted by the patient's joints and determines the torque error, which the exoskeleton compensates for via a spring-damper system, ultimately generating the target trajectory. Finally, the APC ensures adaptive assistive control. The proposed method is validated for its effectiveness in MATLAB/Simulink.

nlin.CD↗

arXiv2025

DispatchMAS: Fusing taxonomy and artificial intelligence agents for emergency medical services

Objective: Emergency medical dispatch (EMD) is a high-stakes process challenged by caller distress, ambiguity, and cognitive load. Large Language Models (LLMs) and Multi-Agent Systems (MAS) offer opportunities to augment dispatchers. This study aimed to develop and evaluate a taxonomy-grounded, LLM-powered multi-agent system for simulating realistic EMD scenarios. Methods: We constructed a clinical taxonomy (32 chief complaints, 6 caller identities from MIMIC-III) and a six-phase call protocol. Using this framework, we developed an AutoGen-based MAS with Caller and Dispatcher Agents. The system grounds interactions in a fact commons to ensure clinical plausibility and mitigate misinformation. We used a hybrid evaluation framework: four physicians assessed 100 simulated cases for "Guidance Efficacy" and "Dispatch Effectiveness," supplemented by automated linguistic analysis (sentiment, readability, politeness). Results: Human evaluation, with substantial inter-rater agreement (Gwe's AC1 > 0.70), confirmed the system's high performance. It demonstrated excellent Dispatch Effectiveness (e.g., 94 % contacting the correct potential other agents) and Guidance Efficacy (advice provided in 91 % of cases), both rated highly by physicians. Algorithmic metrics corroborated these findings, indicating a predominantly neutral affective profile (73.7 % neutral sentiment; 90.4 % neutral emotion), high readability (Flesch 80.9), and a consistently polite style (60.0 % polite; 0 % impolite). Conclusion: Our taxonomy-grounded MAS simulates diverse, clinically plausible dispatch scenarios with high fidelity. Findings support its use for dispatcher training, protocol evaluation, and as a foundation for real-time decision support. This work outlines a pathway for safely integrating advanced AI agents into emergency response workflows.

cs.CL↗