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Wentao Chen

Publications and source records attributed to Wentao Chen.

At least 37 records · Page 2Linked to original sources

Task-based Regularization in Penalized Least-Squares for Binary Signal Detection Tasks in Medical Image Denoising

Image denoising algorithms have been extensively investigated for medical imaging. To perform image denoising, penalized least-squares (PLS) problems can be designed and solved, in which the penalty term encodes prior knowledge of the object being imaged. Sparsity-promoting penalties, such as total variation (TV), have been a popular choice for regularizing image denoising problems. However, such hand-crafted penalties may not be able to preserve task-relevant information in measured image data and can lead to oversmoothed image appearances and patchy artifacts that degrade signal detectability. Supervised learning methods that employ convolutional neural networks (CNNs) have emerged as a popular approach to denoising medical images. However, studies have shown that CNNs trained with loss functions based on traditional image quality measures can lead to a loss of task-relevant information in images. Some previous works have investigated task-based loss functions that employ model observers for training the CNN denoising models. However, such training processes typically require a large number of noisy and ground-truth (noise-free or low-noise) image data pairs. In this work, we propose a task-based regularization strategy for use with PLS in medical image denoising. The proposed task-based regularization is associated with the likelihood of linear test statistics of noisy images for Gaussian noise models. The proposed method does not require ground-truth image data and solves an individual optimization problem for denoising each image. Computer-simulation studies are conducted that consider a multivariate-normally distributed (MVN) lumpy background and a binary texture background. It is demonstrated that the proposed regularization strategy can effectively improve signal detectability in denoised images.

eess.IV↗

Understanding Particles From Video: Property Estimation of Granular Materials via Visuo-Haptic Learning

Granular materials (GMs) are ubiquitous in daily life. Understanding their properties is also important, especially in agriculture and industry. However, existing works require dedicated measurement equipment and also need large human efforts to handle a large number of particles. In this paper, we introduce a method for estimating the relative values of particle size and density from the video of the interaction with GMs. It is trained on a visuo-haptic learning framework inspired by a contact model, which reveals the strong correlation between GM properties and the visual-haptic data during the probe-dragging in the GMs. After training, the network can map the visual modality well to the haptic signal and implicitly characterize the relative distribution of particle properties in its latent embeddings, as interpreted in that contact model. Therefore, we can analyze GM properties using the trained encoder, and only visual information is needed without extra sensory modalities and human efforts for labeling. The presented GM property estimator has been extensively validated via comparison and ablation experiments. The generalization capability has also been evaluated and a real-world application on the beach is also demonstrated. Experiment videos are available at \url{https://sites.google.com/view/gmwork/vhlearning} .

cs.CV↗

Snapshotting Quantum Dynamics at Multiple Time Points

Measurement-induced state disturbance is a major challenge in obtaining quantum statistics at multiple time points. We propose a method to extract dynamic information from a quantum system at intermediate time points, namely snapshotting quantum dynamics. To this end, we apply classical post-processing after performing the ancilla-assisted measurements to cancel out the impact of the measurements at each time point. Based on this, we reconstruct a multi-time quasi-probability distribution (QPD) that correctly recovers the probability distributions at the respective time points. Our approach can also be applied to simultaneously extract exponentially many correlation functions with various time-orderings. We provide a proof-of-principle experimental demonstration of the proposed protocol using a dual-species trapped-ion system by employing $^{171}\rm{Yb}^+$ and $^{138}\rm{Ba}^+$ ions as the system and the ancilla, respectively. Multi-time measurements are performed by repeated initialization and detection of the ancilla state without directly measuring the system state. The two- and three-time QPDs and correlation functions are reconstructed reliably from the experiment, negativity and complex values in the QPDs clearly indicate a contribution of the quantum coherence throughout dynamics.

quant-ph↗

MLAE: Masked LoRA Experts for Visual Parameter-Efficient Fine-Tuning

In response to the challenges posed by the extensive parameter updates required for full fine-tuning of large-scale pre-trained models, parameter-efficient fine-tuning (PEFT) methods, exemplified by Low-Rank Adaptation (LoRA), have emerged. LoRA simplifies the fine-tuning process but may still struggle with a certain level of redundancy in low-rank matrices and limited effectiveness from merely increasing their rank. To address these issues, a natural idea is to enhance the independence and diversity of the learning process for the low-rank matrices. Therefore, we propose Masked LoRA Experts (MLAE), an innovative approach that applies the concept of masking to visual PEFT. Our method incorporates a cellular decomposition strategy that transforms a low-rank matrix into independent rank-1 submatrices, or "experts", thus enhancing independence. Additionally, we introduce a binary mask matrix that selectively activates these experts during training to promote more diverse and anisotropic learning, based on expert-level dropout strategies. Our investigations reveal that this selective activation not only enhances performance but also fosters a more diverse acquisition of knowledge with a marked decrease in parameter similarity among MLAE, significantly boosting the quality of the model. Remarkably, MLAE achieves new state-of-the-art (SOTA) performance with an average accuracy score of 78.8% on the VTAB-1k benchmark and 90.9% on the FGVC benchmark, surpassing the previous SOTA result by an average of 0.8% on both benchmarks with approximately half parameters. Our code is available at https://github.com/jie040109/MLAE.

cs.CV↗

A Single-Ion Information Engine for Charging Quantum Battery

Information engines produce mechanical work through measurement and adaptive control. For information engines, the principal challenge lies in how to store the generated work for subsequent utilization. Here, we report an experimental demonstration where quantized mechanical motion serves as a quantum battery and gets charged in repeated cycles by a single trapped-ion information engine. This is enabled by a key technological advancement in rapid state discrimination, allowing us to suppress measurement-induced disturbances. Consequently, we were able to obtain a charging efficiency over 50\% of the theoretical limit at the optimal temperature. The experimental results substantiate that this approach can render trapped ions a promising platform for microscopic information engines with potential applications in the future upon scaling up.

quant-ph↗

User-Friendly Customized Generation with Multi-Modal Prompts

Text-to-image generation models have seen considerable advancement, catering to the increasing interest in personalized image creation. Current customization techniques often necessitate users to provide multiple images (typically 3-5) for each customized object, along with the classification of these objects and descriptive textual prompts for scenes. This paper questions whether the process can be made more user-friendly and the customization more intricate. We propose a method where users need only provide images along with text for each customization topic, and necessitates only a single image per visual concept. We introduce the concept of a ``multi-modal prompt'', a novel integration of text and images tailored to each customization concept, which simplifies user interaction and facilitates precise customization of both objects and scenes. Our proposed paradigm for customized text-to-image generation surpasses existing finetune-based methods in user-friendliness and the ability to customize complex objects with user-friendly inputs. Our code is available at $\href{https://github.com/zhongzero/Multi-Modal-Prompt}{https://github.com/zhongzero/Multi-Modal-Prompt}$.

cs.CV↗

Improve Cross-Architecture Generalization on Dataset Distillation

Dataset distillation, a pragmatic approach in machine learning, aims to create a smaller synthetic dataset from a larger existing dataset. However, existing distillation methods primarily adopt a model-based paradigm, where the synthetic dataset inherits model-specific biases, limiting its generalizability to alternative models. In response to this constraint, we propose a novel methodology termed "model pool". This approach involves selecting models from a diverse model pool based on a specific probability distribution during the data distillation process. Additionally, we integrate our model pool with the established knowledge distillation approach and apply knowledge distillation to the test process of the distilled dataset. Our experimental results validate the effectiveness of the model pool approach across a range of existing models while testing, demonstrating superior performance compared to existing methodologies.

cs.LG↗

AmbientCycleGAN for Establishing Interpretable Stochastic Object Models Based on Mathematical Phantoms and Medical Imaging Measurements

Medical imaging systems that are designed for producing diagnostically informative images should be objectively assessed via task-based measures of image quality (IQ). Ideally, computation of task-based measures of IQ needs to account for all sources of randomness in the measurement data, including the variability in the ensemble of objects to be imaged. To address this need, stochastic object models (SOMs) that can generate an ensemble of synthesized objects or phantoms can be employed. Various mathematical SOMs or phantoms were developed that can interpretably synthesize objects, such as lumpy object models and parameterized torso phantoms. However, such SOMs that are purely mathematically defined may not be able to comprehensively capture realistic object variations. To establish realistic SOMs, it is desirable to use experimental data. An augmented generative adversarial network (GAN), AmbientGAN, was recently proposed for establishing SOMs from medical imaging measurements. However, it remains unclear to which extent the AmbientGAN-produced objects can be interpretably controlled. This work introduces a novel approach called AmbientCycleGAN that translates mathematical SOMs to realistic SOMs by use of noisy measurement data. Numerical studies that consider clustered lumpy background (CLB) models and real mammograms are conducted. It is demonstrated that our proposed method can stably establish SOMs based on mathematical models and noisy measurement data. Moreover, the ability of the proposed AmbientCycleGAN to interpretably control image features in the synthesized objects is investigated.

eess.IV↗

Ambient-Pix2PixGAN for Translating Medical Images from Noisy Data

Image-to-image translation is a common task in computer vision and has been rapidly increasing the impact on the field of medical imaging. Deep learning-based methods that employ conditional generative adversarial networks (cGANs), such as Pix2PixGAN, have been extensively explored to perform image-to-image translation tasks. However, when noisy medical image data are considered, such methods cannot be directly applied to produce clean images. Recently, an augmented GAN architecture named AmbientGAN has been proposed that can be trained on noisy measurement data to synthesize high-quality clean medical images. Inspired by AmbientGAN, in this work, we propose a new cGAN architecture, Ambient-Pix2PixGAN, for performing medical image-to-image translation tasks by use of noisy measurement data. Numerical studies that consider MRI-to-PET translation are conducted. Both traditional image quality metrics and task-based image quality metrics are employed to assess the proposed Ambient-Pix2PixGAN. It is demonstrated that our proposed Ambient-Pix2PixGAN can be successfully trained on noisy measurement data to produce high-quality translated images in target imaging modality.

eess.IV↗

Unsupervised Generation of Pseudo Normal PET from MRI with Diffusion Model for Epileptic Focus Localization

[$^{18}$F]fluorodeoxyglucose (FDG) positron emission tomography (PET) has emerged as a crucial tool in identifying the epileptic focus, especially in cases where magnetic resonance imaging (MRI) diagnosis yields indeterminate results. FDG PET can provide the metabolic information of glucose and help identify abnormal areas that are not easily found through MRI. However, the effectiveness of FDG PET-based assessment and diagnosis depends on the selection of a healthy control group. The healthy control group typically consists of healthy individuals similar to epilepsy patients in terms of age, gender, and other aspects for providing normal FDG PET data, which will be used as a reference for enhancing the accuracy and reliability of the epilepsy diagnosis. However, significant challenges arise when a healthy PET control group is unattainable. Yaakub \emph{et al.} have previously introduced a Pix2PixGAN-based method for MRI to PET translation. This method used paired MRI and FDG PET scans from healthy individuals for training, and produced pseudo normal FDG PET images from patient MRIs that are subsequently used for lesion detection. However, this approach requires a large amount of high-quality, paired MRI and PET images from healthy control subjects, which may not always be available. In this study, we investigated unsupervised learning methods for unpaired MRI to PET translation for generating pseudo normal FDG PET for epileptic focus localization. Two deep learning methods, CycleGAN and SynDiff, were employed, and we found that diffusion-based method achieved improved performance in accurately localizing the epileptic focus.

cs.CV↗

Exploring the Reasoning Abilities of Multimodal Large Language Models (MLLMs): A Comprehensive Survey on Emerging Trends in Multimodal Reasoning

Strong Artificial Intelligence (Strong AI) or Artificial General Intelligence (AGI) with abstract reasoning ability is the goal of next-generation AI. Recent advancements in Large Language Models (LLMs), along with the emerging field of Multimodal Large Language Models (MLLMs), have demonstrated impressive capabilities across a wide range of multimodal tasks and applications. Particularly, various MLLMs, each with distinct model architectures, training data, and training stages, have been evaluated across a broad range of MLLM benchmarks. These studies have, to varying degrees, revealed different aspects of the current capabilities of MLLMs. However, the reasoning abilities of MLLMs have not been systematically investigated. In this survey, we comprehensively review the existing evaluation protocols of multimodal reasoning, categorize and illustrate the frontiers of MLLMs, introduce recent trends in applications of MLLMs on reasoning-intensive tasks, and finally discuss current practices and future directions. We believe our survey establishes a solid base and sheds light on this important topic, multimodal reasoning.

cs.CL↗

Tree Search-Based Evolutionary Bandits for Protein Sequence Optimization

While modern biotechnologies allow synthesizing new proteins and function measurements at scale, efficiently exploring a protein sequence space and engineering it remains a daunting task due to the vast sequence space of any given protein. Protein engineering is typically conducted through an iterative process of adding mutations to the wild-type or lead sequences, recombination of mutations, and running new rounds of screening. To enhance the efficiency of such a process, we propose a tree search-based bandit learning method, which expands a tree starting from the initial sequence with the guidance of a bandit machine learning model. Under simplified assumptions and a Gaussian Process prior, we provide theoretical analysis and a Bayesian regret bound, demonstrating that the combination of local search and bandit learning method can efficiently discover a near-optimal design. The full algorithm is compatible with a suite of randomized tree search heuristics, machine learning models, pre-trained embeddings, and bandit techniques. We test various instances of the algorithm across benchmark protein datasets using simulated screens. Experiment results demonstrate that the algorithm is both sample-efficient and able to find top designs using reasonably small mutation counts.

q-bio.BM↗

InfiMM-Eval: Complex Open-Ended Reasoning Evaluation For Multi-Modal Large Language Models

Multi-modal Large Language Models (MLLMs) are increasingly prominent in the field of artificial intelligence. These models not only excel in traditional vision-language tasks but also demonstrate impressive performance in contemporary multi-modal benchmarks. Although many of these benchmarks attempt to holistically evaluate MLLMs, they typically concentrate on basic reasoning tasks, often yielding only simple yes/no or multi-choice responses. These methods naturally lead to confusion and difficulties in conclusively determining the reasoning capabilities of MLLMs. To mitigate this issue, we manually curate a benchmark dataset specifically designed for MLLMs, with a focus on complex reasoning tasks. Our benchmark comprises three key reasoning categories: deductive, abductive, and analogical reasoning. The queries in our dataset are intentionally constructed to engage the reasoning capabilities of MLLMs in the process of generating answers. For a fair comparison across various MLLMs, we incorporate intermediate reasoning steps into our evaluation criteria. In instances where an MLLM is unable to produce a definitive answer, its reasoning ability is evaluated by requesting intermediate reasoning steps. If these steps align with our manual annotations, appropriate scores are assigned. This evaluation scheme resembles methods commonly used in human assessments, such as exams or assignments, and represents what we consider a more effective assessment technique compared with existing benchmarks. We evaluate a selection of representative MLLMs using this rigorously developed open-ended multi-step elaborate reasoning benchmark, designed to challenge and accurately measure their reasoning capabilities. The code and data will be released at https://infimm.github.io/InfiMM-Eval/

cs.CV↗

Realization of programmable Ising models in a trapped-ion quantum simulator

A promising paradigm of quantum computing for achieving practical quantum advantages is quantum annealing or quantum approximate optimization algorithm, where the classical problems are encoded in Ising interactions. However, it is challenging to build a quantum system that can efficiently map any structured problems. Here, we present a programmable trapped-ion quantum simulator of an Ising model with all-to-all connectivity with up to four spins. We implement the spin-spin interactions by using the coupling of trapped ions to multiple collective motional modes and realize the programmability through phase modulation of the Raman laser beams that are individually addressed on ions. As an example, we realize several Ising lattices with different interaction connectivities, where the interactions can be ferromagnetic or anti-ferromagnetic. We confirm the programmed interaction geometry by observing the ground states of the corresponding models through quantum state tomography. Our experimental demonstrations serve as an important basis for realizing practical quantum advantages with trapped ions.

quant-ph↗

Active Countermeasures for Email Fraud

As a major component of online crime, email-based fraud is a threat that causes substantial economic losses every year. To counteract these scammers, volunteers called scam-baiters play the roles of victims, reply to scammers, and try to waste their time and attention with long and unproductive conversations. To curb email fraud and magnify the effectiveness of scam-baiting, we developed and deployed an expandable scam-baiting mailserver that can conduct scam-baiting activities automatically. We implemented three reply strategies using three different models and conducted a one-month-long experiment during which we elicited 150 messages from 130 different scammers. We compare the performance of each strategy at attracting and holding the attention of scammers, finding tradeoffs between human-written and automatically-generated response strategies. We also demonstrate that scammers can be engaged concurrently by multiple servers deploying these strategies in a second experiment, which used two server instances to contact 92 different scammers over 12 days. We release both our platform and a dataset containing conversations between our automatic scam-baiters and real human scammers, to support future work in preventing online fraud.

cs.CR↗

Semantic Prompt for Few-Shot Image Recognition

Few-shot learning is a challenging problem since only a few examples are provided to recognize a new class. Several recent studies exploit additional semantic information, e.g. text embeddings of class names, to address the issue of rare samples through combining semantic prototypes with visual prototypes. However, these methods still suffer from the spurious visual features learned from the rare support samples, resulting in limited benefits. In this paper, we propose a novel Semantic Prompt (SP) approach for few-shot learning. Instead of the naive exploitation of semantic information for remedying classifiers, we explore leveraging semantic information as prompts to tune the visual feature extraction network adaptively. Specifically, we design two complementary mechanisms to insert semantic prompts into the feature extractor: one is to enable the interaction between semantic prompts and patch embeddings along the spatial dimension via self-attention, another is to supplement visual features with the transformed semantic prompts along the channel dimension. By combining these two mechanisms, the feature extractor presents a better ability to attend to the class-specific features and obtains more generalized image representations with merely a few support samples. Through extensive experiments on four datasets, the proposed approach achieves promising results, improving the 1-shot learning accuracy by 3.67% on average.

cs.CV↗

Coarse-to-Fine Covid-19 Segmentation via Vision-Language Alignment

Segmentation of COVID-19 lesions can assist physicians in better diagnosis and treatment of COVID-19. However, there are few relevant studies due to the lack of detailed information and high-quality annotation in the COVID-19 dataset. To solve the above problem, we propose C2FVL, a Coarse-to-Fine segmentation framework via Vision-Language alignment to merge text information containing the number of lesions and specific locations of image information. The introduction of text information allows the network to achieve better prediction results on challenging datasets. We conduct extensive experiments on two COVID-19 datasets including chest X-ray and CT, and the results demonstrate that our proposed method outperforms other state-of-the-art segmentation methods.

eess.IV↗

Polymer-Based Self-Calibrated Optical Fiber Tactile Sensor

Human skin can accurately sense the self-decoupled normal and shear forces when in contact with objects of different sizes. Although there exist many soft and conformable tactile sensors on robotic applications able to decouple the normal force and shear forces, the impact of the size of object in contact on the force calibration model has been commonly ignored. Here, using the principle that contact force can be derived from the light power loss in the soft optical fiber core, we present a soft tactile sensor that decouples normal and shear forces and calibrates the measurement results based on the object size, by designing a two-layered weaved polymer-based optical fiber anisotropic structure embedded in a soft elastomer. Based on the anisotropic response of optical fibers, we developed a linear calibration algorithm to simultaneously measure the size of the contact object and the decoupled normal and shear forces calibrated the object size. By calibrating the sensor at the robotic arm tip, we show that robots can reconstruct the force vector at an average accuracy of 0.15N for normal forces, 0.17N for shear forces in X-axis , and 0.18N for shear forces in Y-axis, within the sensing range of 0-2N in all directions, and the average accuracy of object size measurement of 0.4mm, within the test indenter diameter range of 5-12mm.

cs.RO↗