arXiv subjects

Wenxin Deng

Publications and source records attributed to Wenxin Deng.

4 recordsLinked to original sources

arXiv2026

VIP-MINGLE: A Corpus for Videoconference and In-Person Multimodal Interaction in Group Language Engagement

Group conversations are a fundamental yet complex form of social interaction central to human cognition and telecommunication technology. While understanding and facilitating these interactions has been a long-standing goal, findings are often isolated within specific in-person or videoconferencing settings due to a scarcity of datasets that bridge the two. We introduce VIP-MINGLE, a multimodal dataset comprising 59 hours of recordings (32 groups, 105 participants), featuring paired within-subject sessions in both settings. The dataset includes raw audio/video, psychometric data, processed multimodal features (e.g., diarized speech, facial expressions, transcriptions), and time-resolved human annotations. Our analysis reveals significant behavioral distribution shifts across multiple modalities between settings, reinforcing the need for a cross-setting corpus. VIP-MINGLE serves as a critical resource for developing robust models of group conversations across settings.

cs.HC↗

arXiv2025

High-bandwidth photodetector enabled by frequency-domain equalization

High-bandwidth germanium (Ge) photodetectors are crucial for silicon photonic integrated circuits. However, their bandwidth is restricted by carrier transit time and parasitic parameters. In this work, we propose an equalization photodetector (EqPD) utilizing the frequency response of a high-bandwidth photodetector PDA to subtract the frequency response of a low-bandwidth photodetector PDB. With the response of PDB attenuating more severely than PDA at high frequency, the differential frequency response (the response of EqPD) can get higher values at high frequency than at low frequency, flattening the overall frequency response and expanding the bandwidth. Experimental results show that the EqPD has a bandwidth exceeding 110 GHz with a responsivity of 94 mA/W. A 100 Gbaud non-return-to-zero (NRZ) operation without digital signal processing is also demonstrated. To the best of our knowledge, this represents the highest bandwidth in a vertical Ge photodetector, providing a promising solution for high-speed photodetection in next-generation optical communication.

physics.optics↗

arXiv2025

POINT: a web-based platform for pharmacological investigation enhanced by multi-omics networks and knowledge graphs

Network pharmacology (NP) explores pharmacological mechanisms through biological networks. Multi-omics data enable multi-layer network construction under diverse conditions, requiring integration into NP analyses. We developed POINT, a novel NP platform enhanced by multi-omics biological networks, advanced algorithms, and knowledge graphs (KGs) featuring network-based and KG-based analytical functions. In the network-based analysis, users can perform NP studies flexibly using 1,158 multi-omics biological networks encompassing proteins, transcription factors, and non-coding RNAs across diverse cell line-, tissue- and disease-specific conditions. Network-based analysis-including random walk with restart (RWR), GSEA, and diffusion profile (DP) similarity algorithms-supports tasks such as target prediction, functional enrichment, and drug screening. We merged networks from experimental sources to generate a pre-integrated multi-layer human network for evaluation. RWR demonstrated superior performance with a 33.1% average ranking improvement over the second-best algorithm, PageRank, in identifying known targets across 2,002 drugs. Additionally, multi-layer networks significantly improve the ability to identify FDA-approved drug-disease pairs compared to the single-layer network. For KG-based analysis, we compiled three high-quality KGs to construct POINT KG, which cross-references over 90% of network-based predictions. We illustrated the platform's capabilities through two case studies. POINT bridges the gap between multi-omics networks and drug discovery; it is freely accessible at http://point.gene.ac/.

q-bio.MN↗

arXiv2023

PND-Net: Physics based Non-local Dual-domain Network for Metal Artifact Reduction

Metal artifacts caused by the presence of metallic implants tremendously degrade the reconstructed computed tomography (CT) image quality, affecting clinical diagnosis or reducing the accuracy of organ delineation and dose calculation in radiotherapy. Recently, deep learning methods in sinogram and image domains have been rapidly applied on metal artifact reduction (MAR) task. The supervised dual-domain methods perform well on synthesized data, while unsupervised methods with unpaired data are more generalized on clinical data. However, most existing methods intend to restore the corrupted sinogram within metal trace, which essentially remove beam hardening artifacts but ignore other components of metal artifacts, such as scatter, non-linear partial volume effect and noise. In this paper, we mathematically derive a physical property of metal artifacts which is verified via Monte Carlo (MC) simulation and propose a novel physics based non-local dual-domain network (PND-Net) for MAR in CT imaging. Specifically, we design a novel non-local sinogram decomposition network (NSD-Net) to acquire the weighted artifact component, and an image restoration network (IR-Net) is proposed to reduce the residual and secondary artifacts in the image domain. To facilitate the generalization and robustness of our method on clinical CT images, we employ a trainable fusion network (F-Net) in the artifact synthesis path to achieve unpaired learning. Furthermore, we design an internal consistency loss to ensure the integrity of anatomical structures in the image domain, and introduce the linear interpolation sinogram as prior knowledge to guide sinogram decomposition. Extensive experiments on simulation and clinical data demonstrate that our method outperforms the state-of-the-art MAR methods.

physics.med-ph↗