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Wenzheng Cheng

Publications and source records attributed to Wenzheng Cheng.

4 recordsLinked to original sources

Development of 3D Pixel Sensors via an 8-inch CMOS-Compatible Process

In the construction of High-Luminosity Large Hadron Collider (HL-LHC) and Future Circular Collider (FCC) experiments, 3D pixel sensors have become indispensable components due to their superior radiation hardness, fast response, and low power consumption. However, there are still significant challenges in the process of 3D sensors manufacturing. In this work, single devices and arrays of 3D sensors based on 30 $μ$m epitaxial silicon wafer have been designed, simulated, fabricated, and tested. This process was developed on the 8-inch CMOS process platform of the Institute of Microelectronics of the Chinese Academy of Sciences (IMECAS). The key processes include Deep Reactive Ion Etching (DRIE) with the Bosch process, in-situ doping, and an innovative back-etching. After testing the 3D pixel sensors, we have summarized the leakage current and capacitance of devices with different sizes with respect to bias voltages. We also found that the fabricated devices were almost all successfully produced, which laid a strong foundation for subsequent large-scale mass production.

physics.ins-det

Design, fabrication and initial test of a novel 3D-Trench sensor utilizing 8-inch CMOS compatible technology

The 3D silicon sensor has demonstrated excellent performances (signal collection, detection efficiency, power consumption, etc.) comparable or even better with respect to the traditional planar sensor of the ATLAS Detector at the Large Hadron Collider (LHC), especially after the high irradiation fluence, mainly due to the shorter drift length of the generated carriers. These characteristics have made it the most attractive technology for the detection and track reconstruction of charged particles for the High Energy Physics (HEP). In addition, its application is also being explored in astronomy, microdosimetry and medical imaging. This paper will present the design and fabrication of a novel 3D-Trench sensor which features an enclosed deep trench surrounding the central columnar cathode. This novel sensor has been fabricated on the 8-inch COMS pilot line at the Institute of Microelectronics of the Chinese Academy of Sciences (IMECAS) where ultra-narrow etch width of 0.5 μm and the ultra-high depth-to-width ratio (aspect ratio) (>70) have been achieved. Its preliminary simulation and characterization results including electrostatic potential, electric field, Current-Voltage (IV), Capacitance-Voltage (CV), Charge Collection Efficiency (CCE) and Timing Performance before irradiation will be presented in this paper.

physics.ins-det

Towards Robust Algorithms for Surgical Phase Recognition via Digital Twin Representation

Surgical phase recognition (SPR) is an integral component of surgical data science, enabling high-level surgical analysis. End-to-end trained neural networks that predict surgical phase directly from videos have shown excellent performance on benchmarks. However, these models struggle with robustness due to non-causal associations in the training set. Our goal is to improve model robustness to variations in the surgical videos by leveraging the digital twin (DT) paradigm -- an intermediary layer to separate high-level analysis (SPR) from low-level processing. As a proof of concept, we present a DT representation-based framework for SPR from videos. The framework employs vision foundation models with reliable low-level scene understanding to craft DT representation. We embed the DT representation in place of raw video inputs in the state-of-the-art SPR model. The framework is trained on the Cholec80 dataset and evaluated on out-of-distribution (OOD) and corrupted test samples. Contrary to the vulnerability of the baseline model, our framework demonstrates strong robustness on both OOD and corrupted samples, with a video-level accuracy of 80.3 on a highly corrupted Cholec80 test set, 67.9 on the challenging CRCD dataset, and 99.8 on an internal robotic surgery dataset, outperforming the baseline by 3.9, 16.8, and 90.9 respectively. We also find that using DT representation as an augmentation to the raw input can significantly improve model robustness. Our findings lend support to the thesis that DT representations are effective in enhancing model robustness. Future work will seek to improve the feature informativeness and incorporate interpretability for a more comprehensive framework.

cs.CV

DeepHEN: quantitative prediction essential lncRNA genes and rethinking essentialities of lncRNA genes

Gene essentiality refers to the degree to which a gene is necessary for the survival and reproductive efficacy of a living organism. Although the essentiality of non-coding genes has been documented, there are still aspects of non-coding genes' essentiality that are unknown to us. For example, We do not know the contribution of sequence features and network spatial features to essentiality. As a consequence, in this work, we propose DeepHEN that could answer the above question. By buidling a new lncRNA-proteion-protein network and utilizing both representation learning and graph neural network, we successfully build our DeepHEN models that could predict the essentiality of lncRNA genes. Compared to other methods for predicting the essentiality of lncRNA genes, our DeepHEN model not only tells whether sequence features or network spatial features have a greater influence on essentiality but also addresses the overfitting issue of those methods caused by the low number of essential lncRNA genes, as evidenced by the results of enrichment analysis.

q-bio.MN