arXiv subjects

Widemberg S. Nobre

Publications and source records attributed to Widemberg S. Nobre.

3 recordsLinked to original sources

arXiv2026

A Bayesian framework for multilevel data under model mis-specification

We propose a Bayesian framework for uncertainty quantification from the perspective that the working model is mis-specified in settings of a multilevel data-generating process. We focus on settings in which the mis-specification fails to match the functional form of the mean structure, and discuss Bayesian estimation of target parameters under dependence induced by a mismatch between working and data-generating models. The proposal represents a Bayesian semi-parametric procedure aimed at estimating population-level parameters while accounting for cluster- and unit-level variation in the estimating function. The proposal extends the regular Bayesian bootstrap to account for cluster- and unit-level variation using multilevel weights from an enriched Dirichlet model. Simulation studies indicate that the proposed approach has good frequentist properties when the data-generating process and the proposed model induce a partially exchangeable sequence associated with the unknown quantity of interest. Applications to radon (Gelman and Hill, 2007), Programme for International Student Assessment 2022 (OECD, 2023), and tuberculosis (Nobre et al., 2023) datasets are presented for illustrative purposes. The results demonstrate that the proposed method is competitive with variations of multilevel models, with major differences observed in the range of credible intervals, which are justified by the nonparametric assumptions underlying the proposed method.

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arXiv2023

The impact of directly observed therapy on the efficacy of Tuberculosis treatment: A Bayesian multilevel approach

We propose and discuss a Bayesian procedure to estimate the average treatment effect (ATE) for multilevel observations in the presence of confounding. We focus on situations where the confounders may be latent (e.g., spatial latent effects). This work is motivated by an interest in determining the causal impact of directly observed therapy (DOT) on the successful treatment of Tuberculosis (TB); the available data correspond to individual-level information observed across different cities in a state in Brazil. We focus on propensity score regression and covariate adjustment to balance the treatment (DOT) allocation. We discuss the need to include latent local-level random effects in the propensity score model to reduce bias in the estimation of the ATE. A simulation study suggests that accounting for the multilevel nature of the data with latent structures in both the outcome and propensity score models has the potential to reduce bias in the estimation of causal effects.

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arXiv2022

Causal inference under mis-specification: adjustment based on the propensity score

We study Bayesian approaches to causal inference via propensity score regression. Much of the Bayesian literature on propensity score methods have relied on approaches that cannot be viewed as fully Bayesian in the context of conventional `likelihood times prior' posterior inference; in addition, most methods rely on parametric and distributional assumptions, and presumed correct specification. We emphasize that causal inference is typically carried out in settings of mis-specification, and develop strategies for fully Bayesian inference that reflect this. We focus on methods based on decision-theoretic arguments, and show how inference based on loss-minimization can give valid and fully Bayesian inference. We propose a computational approach to inference based on the Bayesian bootstrap which has good Bayesian and frequentist properties.

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