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Winnie Li

Publications and source records attributed to Winnie Li.

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Understanding When Graph Convolutional Networks Help: A Diagnostic Study on Label Scarcity and Structural Properties

Graph Convolutional Networks (GCNs) have become a standard approach for semi-supervised node classification, yet practitioners lack clear guidance on when GCNs provide meaningful improvements over simpler baselines. We present a diagnostic study using the Amazon Computers co-purchase data to understand when and why GCNs help. Through systematic experiments with simulated label scarcity, feature ablation, and per-class analysis, we find that GCN performance depends critically on the interaction between graph homophily and feature quality. GCNs provide the largest gains under extreme label scarcity, where they leverage neighborhood structure to compensate for limited supervision. Surprisingly, GCNs can match their original performance even when node features are replaced with random noise, suggesting that structure alone carries sufficient signal on highly homophilous graphs. However, GCNs hurt performance when homophily is low and features are already strong, as noisy neighbors corrupt good predictions. Our quadrant analysis reveals that GCNs help in three of four conditions and only hurt when low homophily meets strong features. These findings offer practical guidance for practitioners deciding whether to adopt graph-based methods.

cs.LG

Geometric and Dosimetric Validation of Deformable Image Registration for Prostate MR-guided Adaptive Radiotherapy

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25 patients treated with 30 Gy in 5 fractions on a 1.5 T MR-linac using an adaptive workflow. A reference MR was used for planning, with three images collected at each fraction: adapt MR for adaptive planning, verify MR for pretreatment position verification and beam-on for capturing anatomy during radiation delivery. We assessed three DIR approaches: intensity-based, intensity-based with controlling structures (CS) and novel intensity based with controlling structures and points of interest (CS+P). DIRs were performed between the reference and fraction images and within fractions. We propagated CTV, bladder, and rectum contours using the DIRs and compared to manual contours using Dice similarity coefficient, mean distance to agreement (DTAmean), and dose-volume metrics. Results: CS and CS+P improved geometric agreement between contours over intensity-only DIR. DTAmean for reference-to-beam-on intensity-only DIR was 0.131+/-0.009cm (CTV), 0.46+/-0.08cm (bladder), and 0.154+/-0.013cm (rectum). For the CS, the values were 0.018+/-0.002cm, 0.388+/-0.14cm, and 0.036+/-0.013cm. For CS+P these values were 0.015+/-0.001cm, 0.025+/-0.004cm, and 0.021+/-0.002cm. Dosimetrically, comparing CS and CS+P for reference to beam-on DIRs resulted in a change of CTV D98% from [-29cGy, 19cGy] to [-18cGy, 26cGy], rectum D1cc from [-106cGy, 72cGy] to [-52cGy, 74cGy], and bladder D5cc from [-51cGy, 544cGy] to [-79cGy, 36cGy]. Significance: CS improved geometric and dosimetric accuracy over intensity-only DIR, with CS+P providing the most consistent performance. However, session image segmentation remains a challenge, which may be addressed with automated contouring.

physics.med-ph