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Xian Wu

Publications and source records attributed to Xian Wu.

At least 127 records · Page 7Linked to original sources

Soft-Label Integration for Robust Toxicity Classification

Toxicity classification in textual content remains a significant problem. Data with labels from a single annotator fall short of capturing the diversity of human perspectives. Therefore, there is a growing need to incorporate crowdsourced annotations for training an effective toxicity classifier. Additionally, the standard approach to training a classifier using empirical risk minimization (ERM) may fail to address the potential shifts between the training set and testing set due to exploiting spurious correlations. This work introduces a novel bi-level optimization framework that integrates crowdsourced annotations with the soft-labeling technique and optimizes the soft-label weights by Group Distributionally Robust Optimization (GroupDRO) to enhance the robustness against out-of-distribution (OOD) risk. We theoretically prove the convergence of our bi-level optimization algorithm. Experimental results demonstrate that our approach outperforms existing baseline methods in terms of both average and worst-group accuracy, confirming its effectiveness in leveraging crowdsourced annotations to achieve more effective and robust toxicity classification.

cs.AI↗

GSCo: Towards Generalizable AI in Medicine via Generalist-Specialist Collaboration

Generalist foundation models (GFMs) are renowned for their exceptional capability and flexibility in effectively generalizing across diverse tasks and modalities. In the field of medicine, while GFMs exhibit superior generalizability based on their extensive intrinsic knowledge as well as proficiency in instruction following and in-context learning, specialist models excel in precision due to their domain knowledge. In this work, for the first time, we explore the synergy between the GFM and specialist models, to enable precise medical image analysis on a broader scope. Specifically, we propose a cooperative framework, Generalist-Specialist Collaboration (GSCo), which consists of two stages, namely the construction of GFM and specialists, and collaborative inference on downstream tasks. In the construction stage, we develop MedDr, the largest open-source GFM tailored for medicine, showcasing exceptional instruction-following and in-context learning capabilities. Meanwhile, a series of lightweight specialists are crafted for downstream tasks with low computational cost. In the collaborative inference stage, we introduce two cooperative mechanisms, Mixture-of-Expert Diagnosis and Retrieval-Augmented Diagnosis, to harvest the generalist's in-context learning abilities alongside the specialists' domain expertise. For a comprehensive evaluation, we curate a large-scale benchmark featuring 28 datasets and about 250,000 images. Extensive results demonstrate that MedDr consistently outperforms state-of-the-art GFMs on downstream datasets. Furthermore, GSCo exceeds both GFMs and specialists across all out-of-domain disease diagnosis datasets. These findings indicate a significant paradigm shift in the application of GFMs, transitioning from separate models for specific tasks to a collaborative approach between GFMs and specialists, thereby advancing the frontiers of generalizable AI in medicine.

cs.CV↗

LLM-ESR: Large Language Models Enhancement for Long-tailed Sequential Recommendation

Sequential recommender systems (SRS) aim to predict users' subsequent choices based on their historical interactions and have found applications in diverse fields such as e-commerce and social media. However, in real-world systems, most users interact with only a handful of items, while the majority of items are seldom consumed. These two issues, known as the long-tail user and long-tail item challenges, often pose difficulties for existing SRS. These challenges can adversely affect user experience and seller benefits, making them crucial to address. Though a few works have addressed the challenges, they still struggle with the seesaw or noisy issues due to the intrinsic scarcity of interactions. The advancements in large language models (LLMs) present a promising solution to these problems from a semantic perspective. As one of the pioneers in this field, we propose the Large Language Models Enhancement framework for Sequential Recommendation (LLM-ESR). This framework utilizes semantic embeddings derived from LLMs to enhance SRS without adding extra inference load from LLMs. To address the long-tail item challenge, we design a dual-view modeling framework that combines semantics from LLMs and collaborative signals from conventional SRS. For the long-tail user challenge, we propose a retrieval augmented self-distillation method to enhance user preference representation using more informative interactions from similar users. To verify the effectiveness and versatility of our proposed enhancement framework, we conduct extensive experiments on three real-world datasets using three popular SRS models. The results show that our method surpasses existing baselines consistently, and benefits long-tail users and items especially. The implementation code is available at https://github.com/Applied-Machine-Learning-Lab/LLM-ESR.

cs.IR↗

Large Language Models for Generative Information Extraction: A Survey

Information extraction (IE) aims to extract structural knowledge from plain natural language texts. Recently, generative Large Language Models (LLMs) have demonstrated remarkable capabilities in text understanding and generation. As a result, numerous works have been proposed to integrate LLMs for IE tasks based on a generative paradigm. To conduct a comprehensive systematic review and exploration of LLM efforts for IE tasks, in this study, we survey the most recent advancements in this field. We first present an extensive overview by categorizing these works in terms of various IE subtasks and techniques, and then we empirically analyze the most advanced methods and discover the emerging trend of IE tasks with LLMs. Based on a thorough review conducted, we identify several insights in technique and promising research directions that deserve further exploration in future studies. We maintain a public repository and consistently update related works and resources on GitHub (\href{https://github.com/quqxui/Awesome-LLM4IE-Papers}{LLM4IE repository})

cs.CL↗

Mitigating Hallucinations of Large Language Models in Medical Information Extraction via Contrastive Decoding

The impressive capabilities of large language models (LLMs) have attracted extensive interests of applying LLMs to medical field. However, the complex nature of clinical environments presents significant hallucination challenges for LLMs, hindering their widespread adoption. In this paper, we address these hallucination issues in the context of Medical Information Extraction (MIE) tasks by introducing ALternate Contrastive Decoding (ALCD). We begin by redefining MIE tasks as an identify-and-classify process. We then separate the identification and classification functions of LLMs by selectively masking the optimization of tokens during fine-tuning. During the inference stage, we alternately contrast output distributions derived from sub-task models. This approach aims to selectively enhance the identification and classification capabilities while minimizing the influence of other inherent abilities in LLMs. Additionally, we propose an alternate adaptive constraint strategy to more effectively adjust the scale and scope of contrastive tokens. Through comprehensive experiments on two different backbones and six diverse medical information extraction tasks, ALCD demonstrates significant improvements in resolving hallucination issues compared to conventional decoding methods.

cs.CL↗

Editing Factual Knowledge and Explanatory Ability of Medical Large Language Models

Model editing aims to precisely alter the behaviors of large language models (LLMs) in relation to specific knowledge, while leaving unrelated knowledge intact. This approach has proven effective in addressing issues of hallucination and outdated information in LLMs. However, the potential of using model editing to modify knowledge in the medical field remains largely unexplored, even though resolving hallucination is a pressing need in this area. Our observations indicate that current methods face significant challenges in dealing with specialized and complex knowledge in medical domain. Therefore, we propose MedLaSA, a novel Layer-wise Scalable Adapter strategy for medical model editing. MedLaSA harnesses the strengths of both adding extra parameters and locate-then-edit methods for medical model editing. We utilize causal tracing to identify the association of knowledge in neurons across different layers, and generate a corresponding scale set from the association value for each piece of knowledge. Subsequently, we incorporate scalable adapters into the dense layers of LLMs. These adapters are assigned scaling values based on the corresponding specific knowledge, which allows for the adjustment of the adapter's weight and rank. The more similar the content, the more consistent the scale between them. This ensures precise editing of semantically identical knowledge while avoiding impact on unrelated knowledge. To evaluate the editing impact on the behaviours of LLMs, we propose two model editing studies for medical domain: (1) editing factual knowledge for medical specialization and (2) editing the explanatory ability for complex knowledge. We build two novel medical benchmarking datasets and introduce a series of challenging and comprehensive metrics. Extensive experiments on medical LLMs demonstrate the editing efficiency of MedLaSA, without affecting unrelated knowledge.

cs.CL↗

RockTrack: A 3D Robust Multi-Camera-Ken Multi-Object Tracking Framework

3D Multi-Object Tracking (MOT) obtains significant performance improvements with the rapid advancements in 3D object detection, particularly in cost-effective multi-camera setups. However, the prevalent end-to-end training approach for multi-camera trackers results in detector-specific models, limiting their versatility. Moreover, current generic trackers overlook the unique features of multi-camera detectors, i.e., the unreliability of motion observations and the feasibility of visual information. To address these challenges, we propose RockTrack, a 3D MOT method for multi-camera detectors. Following the Tracking-By-Detection framework, RockTrack is compatible with various off-the-shelf detectors. RockTrack incorporates a confidence-guided preprocessing module to extract reliable motion and image observations from distinct representation spaces from a single detector. These observations are then fused in an association module that leverages geometric and appearance cues to minimize mismatches. The resulting matches are propagated through a staged estimation process, forming the basis for heuristic noise modeling. Additionally, we introduce a novel appearance similarity metric for explicitly characterizing object affinities in multi-camera settings. RockTrack achieves state-of-the-art performance on the nuScenes vision-only tracking leaderboard with 59.1% AMOTA while demonstrating impressive computational efficiency.

cs.CV↗

A semi-analytical method using auxiliary sine series for vibration and sound radiation of a rectangular plate with elastic edges

This paper proposes an efficient semi-analytical method using auxiliary sine series for transverse vibration and sound radiation of a thin rectangular plate with edges elastically restrained against translation and rotation. The formulation, constructed by two-dimensional sine and/or cosine series, can approximately express the bending displacement, and calculate vibration and sound radiation under excitation of point force, arbitrary-angle plane wave, or diffuse acoustic field with acceptable accuracy. It is also applied for baffled or unbaffled conditions. A post-process program is developed to predict vibrating frequencies and modes, mean square velocity spectrum, and sound transmission loss via reduced-order integrals of radiation impedances. The method is validated by experiment and simulation results, demonstrating accurate and efficient computation using a single program for transverse vibration and sound radiation of a plate under different elastic boundary conditions and different excitations. Formulas given in this paper provide a basis for the code development on transverse vibration and sound radiation analysis of thin plates.

physics.app-ph↗

Fast-Poly: A Fast Polyhedral Framework For 3D Multi-Object Tracking

3D Multi-Object Tracking (MOT) captures stable and comprehensive motion states of surrounding obstacles, essential for robotic perception. However, current 3D trackers face issues with accuracy and latency consistency. In this paper, we propose Fast-Poly, a fast and effective filter-based method for 3D MOT. Building upon our previous work Poly-MOT, Fast-Poly addresses object rotational anisotropy in 3D space, enhances local computation densification, and leverages parallelization technique, improving inference speed and precision. Fast-Poly is extensively tested on two large-scale tracking benchmarks with Python implementation. On the nuScenes dataset, Fast-Poly achieves new state-of-the-art performance with 75.8% AMOTA among all methods and can run at 34.2 FPS on a personal CPU. On the Waymo dataset, Fast-Poly exhibits competitive accuracy with 63.6% MOTA and impressive inference speed (35.5 FPS). The source code is publicly available at https://github.com/lixiaoyu2000/FastPoly.

cs.CV↗

A Survey of Large Language Models in Medicine: Progress, Application, and Challenge

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of LLMs in supporting different medical tasks (e.g., enhancing clinical diagnostics and providing medical education), a review of these efforts, particularly their development, practical applications, and outcomes in medicine, remains scarce. Therefore, this review aims to provide a detailed overview of the development and deployment of LLMs in medicine, including the challenges and opportunities they face. In terms of development, we provide a detailed introduction to the principles of existing medical LLMs, including their basic model structures, number of parameters, and sources and scales of data used for model development. It serves as a guide for practitioners in developing medical LLMs tailored to their specific needs. In terms of deployment, we offer a comparison of the performance of different LLMs across various medical tasks, and further compare them with state-of-the-art lightweight models, aiming to provide an understanding of the advantages and limitations of LLMs in medicine. Overall, in this review, we address the following questions: 1) What are the practices for developing medical LLMs 2) How to measure the medical task performance of LLMs in a medical setting? 3) How have medical LLMs been employed in real-world practice? 4) What challenges arise from the use of medical LLMs? and 5) How to more effectively develop and deploy medical LLMs? By answering these questions, this review aims to provide insights into the opportunities for LLMs in medicine and serve as a practical resource. We also maintain a regularly updated list of practical guides on medical LLMs at https://github.com/AI-in-Health/MedLLMsPracticalGuide

cs.CL↗

Retrieval-Augmented and Knowledge-Grounded Language Models for Faithful Clinical Medicine

Language models (LMs), including large language models (such as ChatGPT), have the potential to assist clinicians in generating various clinical notes. However, LMs are prone to produce ``hallucinations'', i.e., generated content that is not aligned with facts and knowledge. In this paper, we propose the Re$^3$Writer method with retrieval-augmented generation and knowledge-grounded reasoning to enable LMs to generate faithful clinical texts. We demonstrate the effectiveness of our method in generating patient discharge instructions. It requires the LMs not to only understand the patients' long clinical documents, i.e., the health records during hospitalization, but also to generate critical instructional information provided both to carers and to the patient at the time of discharge. The proposed Re$^3$Writer imitates the working patterns of physicians to first \textbf{re}trieve related working experience from historical instructions written by physicians, then \textbf{re}ason related medical knowledge. Finally, it \textbf{re}fines the retrieved working experience and reasoned medical knowledge to extract useful information, which is used to generate the discharge instructions for previously-unseen patients. Our experiments show that, using our method, the performance of five representative LMs can be substantially boosted across all metrics. Meanwhile, we show results from human evaluations to measure the effectiveness in terms of fluency, faithfulness, and comprehensiveness.

cs.CL↗

Precision frequency tuning of tunable transmon qubits using alternating-bias assisted annealing

Superconducting quantum processors are one of the leading platforms for realizing scalable fault-tolerant quantum computation (FTQC). The recent demonstration of post-fabrication tuning of Josephson junctions using alternating-bias assisted annealing (ABAA) technique and a reduction in junction loss after ABAA illuminates a promising path towards precision tuning of qubit frequency while maintaining high coherence. Here, we demonstrate precision tuning of the maximum $|0\rangle\rightarrow |1\rangle$ transition frequency ($f_{01}^{\rm max}$) of tunable transmon qubits by performing ABAA at room temperature using commercially available test equipment. We characterize the impact of junction relaxation and aging on resistance spread after tuning, and demonstrate a frequency equivalent tuning precision of 7.7 MHz ($0.17\%$) based on targeted resistance tuning on hundreds of qubits, with a resistance tuning range up to $18.5\%$. Cryogenic measurements on tuned and untuned qubits show evidence of improved coherence after ABAA with no significant impact on tunability. Despite a small global offset, we show an empirical $f_{01}^{\rm max}$ tuning precision of 18.4 MHz by tuning a set of multi-qubit processors targeting their designed Hamiltonians. We experimentally characterize high-fidelity parametric resonance iSWAP gates on two ABAA-tuned 9-qubit processors with fidelity as high as $99.51\pm 0.20\%$. On the best-performing device, we measured across the device a median fidelity of $99.22\%$ and an average fidelity of $99.13\pm 0.12 \%$. Yield modeling analysis predicts high detuning-edge-yield using ABAA beyond the 1000-qubit scale. These results demonstrate the cutting-edge capability of frequency targeting using ABAA and open up a new avenue to systematically improving Hamiltonian targeting and optimization for scaling high-performance superconducting quantum processors.

quant-ph↗

RepAct: The Re-parameterizable Adaptive Activation Function

Addressing the imperative need for efficient artificial intelligence in IoT and edge computing, this study presents RepAct, a re-parameterizable adaptive activation function tailored for optimizing lightweight neural networks within the computational limitations of edge devices. By employing a multi-branch structure with learnable adaptive weights, RepAct enriches feature processing and enhances cross-layer interpretability. When evaluated on tasks such as image classification and object detection, RepAct notably surpassed conventional activation functions in lightweight networks, delivering up to a 7.92% accuracy boost on MobileNetV3-Small for the ImageNet100 dataset, while maintaining computational complexity on par with HardSwish. This innovative approach not only maximizes model parameter efficiency but also significantly improves the performance and understanding capabilities of lightweight neural networks, demonstrating its potential for real-time edge computing applications.

cs.LG↗

Guiding Clinical Reasoning with Large Language Models via Knowledge Seeds

Clinical reasoning refers to the cognitive process that physicians employ in evaluating and managing patients. This process typically involves suggesting necessary examinations, diagnosing patients' diseases, and deciding on appropriate therapies, etc. Accurate clinical reasoning requires extensive medical knowledge and rich clinical experience, setting a high bar for physicians. This is particularly challenging in developing countries due to the overwhelming number of patients and limited physician resources, contributing significantly to global health inequity and necessitating automated clinical reasoning approaches. Recently, the emergence of large language models (LLMs) such as ChatGPT and GPT-4 have demonstrated their potential in clinical reasoning. However, these LLMs are prone to hallucination problems, and the reasoning process of LLMs may not align with the clinical decision path of physicians. In this study, we introduce a novel framework, In-Context Padding (ICP), designed to enhance LLMs with medical knowledge. Specifically, we infer critical clinical reasoning elements (referred to as knowledge seeds) and use these as anchors to guide the generation process of LLMs. Experiments on two clinical question datasets demonstrate that ICP significantly improves the clinical reasoning ability of LLMs.

cs.CL↗

RICE: Breaking Through the Training Bottlenecks of Reinforcement Learning with Explanation

Deep reinforcement learning (DRL) is playing an increasingly important role in real-world applications. However, obtaining an optimally performing DRL agent for complex tasks, especially with sparse rewards, remains a significant challenge. The training of a DRL agent can be often trapped in a bottleneck without further progress. In this paper, we propose RICE, an innovative refining scheme for reinforcement learning that incorporates explanation methods to break through the training bottlenecks. The high-level idea of RICE is to construct a new initial state distribution that combines both the default initial states and critical states identified through explanation methods, thereby encouraging the agent to explore from the mixed initial states. Through careful design, we can theoretically guarantee that our refining scheme has a tighter sub-optimality bound. We evaluate RICE in various popular RL environments and real-world applications. The results demonstrate that RICE significantly outperforms existing refining schemes in enhancing agent performance.

cs.LG↗

ZeroNLG: Aligning and Autoencoding Domains for Zero-Shot Multimodal and Multilingual Natural Language Generation

Natural Language Generation (NLG) accepts input data in the form of images, videos, or text and generates corresponding natural language text as output. Existing NLG methods mainly adopt a supervised approach and rely heavily on coupled data-to-text pairs. However, for many targeted scenarios and for non-English languages, sufficient quantities of labeled data are often not available. To relax the dependency on labeled data of downstream tasks, we propose an intuitive and effective zero-shot learning framework, ZeroNLG, which can deal with multiple NLG tasks, including image-to-text (image captioning), video-to-text (video captioning), and text-to-text (neural machine translation), across English, Chinese, German, and French within a unified framework. ZeroNLG does not require any labeled downstream pairs for training. During training, ZeroNLG (i) projects different domains (across modalities and languages) to corresponding coordinates in a shared common latent space; (ii) bridges different domains by aligning their corresponding coordinates in this space; and (iii) builds an unsupervised multilingual auto-encoder to learn to generate text by reconstructing the input text given its coordinate in shared latent space. Consequently, during inference, based on the data-to-text pipeline, ZeroNLG can generate target sentences across different languages given the coordinate of input data in the common space. Within this unified framework, given visual (imaging or video) data as input, ZeroNLG can perform zero-shot visual captioning; given textual sentences as input, ZeroNLG can perform zero-shot machine translation. We present the results of extensive experiments on twelve NLG tasks, showing that, without using any labeled downstream pairs for training, ZeroNLG generates high-quality and believable outputs and significantly outperforms existing zero-shot methods.

cs.CL↗

When MOE Meets LLMs: Parameter Efficient Fine-tuning for Multi-task Medical Applications

The recent surge in Large Language Models (LLMs) has garnered significant attention across numerous fields. Fine-tuning is often required to fit general LLMs for a specific domain, like the web-based healthcare system. However, two problems arise during fine-tuning LLMs for medical applications. One is the task variety problem, which involves distinct tasks in real-world medical scenarios. The variety often leads to sub-optimal fine-tuning for data imbalance and seesaw problems. Besides, the large amount of parameters in LLMs leads to huge time and computation consumption by fine-tuning. To address these two problems, we propose a novel parameter efficient fine-tuning framework for multi-task medical applications, dubbed as MOELoRA. The designed framework aims to absorb both the benefits of mixture-of-expert (MOE) for multi-task learning and low-rank adaptation (LoRA) for parameter efficient fine-tuning. For unifying MOE and LoRA, we devise multiple experts as the trainable parameters, where each expert consists of a pair of low-rank matrices to retain the small size of trainable parameters. Then, a task-motivated gate function for all MOELoRA layers is proposed, which can control the contributions of each expert and produce distinct parameters for various tasks. We conduct experiments on a multi-task medical dataset, indicating MOELoRA outperforms the existing parameter efficient fine-tuning methods. The code is available online.

cs.CL↗

Biomedical Entity Linking as Multiple Choice Question Answering

Although biomedical entity linking (BioEL) has made significant progress with pre-trained language models, challenges still exist for fine-grained and long-tailed entities. To address these challenges, we present BioELQA, a novel model that treats Biomedical Entity Linking as Multiple Choice Question Answering. BioELQA first obtains candidate entities with a fast retriever, jointly presents the mention and candidate entities to a generator, and then outputs the predicted symbol associated with its chosen entity. This formulation enables explicit comparison of different candidate entities, thus capturing fine-grained interactions between mentions and entities, as well as among entities themselves. To improve generalization for long-tailed entities, we retrieve similar labeled training instances as clues and concatenate the input with retrieved instances for the generator. Extensive experimental results show that BioELQA outperforms state-of-the-art baselines on several datasets.

cs.CL↗