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Xiang 'Anthony' Chen

Publications and source records attributed to Xiang 'Anthony' Chen.

At least 37 records · Page 2Linked to original sources

Supporting Mitosis Detection AI Training with Inter-Observer Eye-Gaze Consistencies

The expansion of artificial intelligence (AI) in pathology tasks has intensified the demand for doctors' annotations in AI development. However, collecting high-quality annotations from doctors is costly and time-consuming, creating a bottleneck in AI progress. This study investigates eye-tracking as a cost-effective technology to collect doctors' behavioral data for AI training with a focus on the pathology task of mitosis detection. One major challenge in using eye-gaze data is the low signal-to-noise ratio, which hinders the extraction of meaningful information. We tackled this by levering the properties of inter-observer eye-gaze consistencies and creating eye-gaze labels from consistent eye-fixations shared by a group of observers. Our study involved 14 non-medical participants, from whom we collected eye-gaze data and generated eye-gaze labels based on varying group sizes. We assessed the efficacy of such eye-gaze labels by training Convolutional Neural Networks (CNNs) and comparing their performance to those trained with ground truth annotations and a heuristic-based baseline. Results indicated that CNNs trained with our eye-gaze labels closely followed the performance of ground-truth-based CNNs, and significantly outperformed the baseline. Although primarily focused on mitosis, we envision that insights from this study can be generalized to other medical imaging tasks.

cs.CV↗

Human I/O: Towards a Unified Approach to Detecting Situational Impairments

Situationally Induced Impairments and Disabilities (SIIDs) can significantly hinder user experience in contexts such as poor lighting, noise, and multi-tasking. While prior research has introduced algorithms and systems to address these impairments, they predominantly cater to specific tasks or environments and fail to accommodate the diverse and dynamic nature of SIIDs. We introduce Human I/O, a unified approach to detecting a wide range of SIIDs by gauging the availability of human input/output channels. Leveraging egocentric vision, multimodal sensing and reasoning with large language models, Human I/O achieves a 0.22 mean absolute error and a 82% accuracy in availability prediction across 60 in-the-wild egocentric video recordings in 32 different scenarios. Furthermore, while the core focus of our work is on the detection of SIIDs rather than the creation of adaptive user interfaces, we showcase the efficacy of our prototype via a user study with 10 participants. Findings suggest that Human I/O significantly reduces effort and improves user experience in the presence of SIIDs, paving the way for more adaptive and accessible interactive systems in the future.

cs.HC↗

HCI Papers Cite HCI Papers, Increasingly So

To measure how HCI papers are cited across disciplinary boundaries, we collected a citation dataset of CHI, UIST, and CSCW papers published between 2010 and 2020. Our analysis indicates that HCI papers have been more and more likely to be cited by HCI papers rather than by non-HCI papers.

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Domain generalization across tumor types, laboratories, and species -- insights from the 2022 edition of the Mitosis Domain Generalization Challenge

Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with deterioration of algorithmic performance under shifts in image representations. Considerable covariate shifts occur when assessment is performed on different tumor types, images are acquired using different digitization devices, or specimens are produced in different laboratories. This observation motivated the inception of the 2022 challenge on MItosis Domain Generalization (MIDOG 2022). The challenge provided annotated histologic tumor images from six different domains and evaluated the algorithmic approaches for mitotic figure detection provided by nine challenge participants on ten independent domains. Ground truth for mitotic figure detection was established in two ways: a three-expert consensus and an independent, immunohistochemistry-assisted set of labels. This work represents an overview of the challenge tasks, the algorithmic strategies employed by the participants, and potential factors contributing to their success. With an $F_1$ score of 0.764 for the top-performing team, we summarize that domain generalization across various tumor domains is possible with today's deep learning-based recognition pipelines. However, we also found that domain characteristics not present in the training set (feline as new species, spindle cell shape as new morphology and a new scanner) led to small but significant decreases in performance. When assessed against the immunohistochemistry-assisted reference standard, all methods resulted in reduced recall scores, but with only minor changes in the order of participants in the ranking.

cs.CV↗

Next Steps for Human-Centered Generative AI: A Technical Perspective

Through iterative, cross-disciplinary discussions, we define and propose next-steps for Human-centered Generative AI (HGAI). We contribute a comprehensive research agenda that lays out future directions of Generative AI spanning three levels: aligning with human values; assimilating human intents; and augmenting human abilities. By identifying these next-steps, we intend to draw interdisciplinary research teams to pursue a coherent set of emergent ideas in HGAI, focusing on their interested topics while maintaining a coherent big picture of the future work landscape.

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Marvista: Exploring the Design of a Human-AI Collaborative News Reading Tool

We explore the design of Marvista -- a human-AI collaborative tool that employs a suite of natural language processing models to provide end-to-end support for reading online news articles. Before reading an article, Marvista helps a user plan what to read by filtering text based on how much time one can spend and what questions one is interested to find out from the article. During reading, Marvista helps the user reflect on their understanding of each paragraph with AI-generated questions. After reading, Marvista generates an explainable human-AI summary that combines both AI's processing of the text, the user's reading behavior, and user-generated data in the reading process. In contrast to prior work that offered (content-independent) interaction techniques or devices for reading, Marvista takes a human-AI collaborative approach that contributes text-specific guidance (content-aware) to support the entire reading process.

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AVscript: Accessible Video Editing with Audio-Visual Scripts

Sighted and blind and low vision (BLV) creators alike use videos to communicate with broad audiences. Yet, video editing remains inaccessible to BLV creators. Our formative study revealed that current video editing tools make it difficult to access the visual content, assess the visual quality, and efficiently navigate the timeline. We present AVscript, an accessible text-based video editor. AVscript enables BLV creators to edit their video using a script that embeds the video's visual content, visual errors (e.g., dark or blurred footage), and speech. BLV creators can use AVscript to efficiently navigate between scenes and visual errors or to locate objects in the frame or spoken words of interest. A comparison study (N=12) showed that AVscript significantly lowered BLV creators' mental demands while increasing confidence and independence in video editing. We further demonstrate the potential of AVscript through an exploratory study (N=3) where BLV creators edited their own footage.

cs.HC↗

Designing and Evaluating Interfaces that Highlight News Coverage Diversity Using Discord Questions

Modern news aggregators do the hard work of organizing a large news stream, creating collections for a given news story with tens of source options. This paper shows that navigating large source collections for a news story can be challenging without further guidance. In this work, we design three interfaces -- the Annotated Article, the Recomposed Article, and the Question Grid -- aimed at accompanying news readers in discovering coverage diversity while they read. A first usability study with 10 journalism experts confirms the designed interfaces all reveal coverage diversity and determine each interface's potential use cases and audiences. In a second usability study, we developed and implemented a reading exercise with 95 novice news readers to measure exposure to coverage diversity. Results show that Annotated Article users are able to answer questions 34% more completely than with two existing interfaces while finding the interface equally easy to use.

cs.HC↗

Augmenting Pathologists with NaviPath: Design and Evaluation of a Human-AI Collaborative Navigation System

Artificial Intelligence (AI) brings advancements to support pathologists in navigating high-resolution tumor images to search for pathology patterns of interest. However, existing AI-assisted tools have not realized this promised potential due to a lack of insight into pathology and HCI considerations for pathologists' navigation workflows in practice. We first conducted a formative study with six medical professionals in pathology to capture their navigation strategies. By incorporating our observations along with the pathologists' domain knowledge, we designed NaviPath -- a human-AI collaborative navigation system. An evaluation study with 15 medical professionals in pathology indicated that: (i) compared to the manual navigation, participants saw more than twice the number of pathological patterns in unit time with NaviPath, and (ii) participants achieved higher precision and recall against the AI and the manual navigation on average. Further qualitative analysis revealed that navigation was more consistent with NaviPath, which can improve the overall examination quality.

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GANravel: User-Driven Direction Disentanglement in Generative Adversarial Networks

Generative adversarial networks (GANs) have many application areas including image editing, domain translation, missing data imputation, and support for creative work. However, GANs are considered 'black boxes'. Specifically, the end-users have little control over how to improve editing directions through disentanglement. Prior work focused on new GAN architectures to disentangle editing directions. Alternatively, we propose GANravel a user-driven direction disentanglement tool that complements the existing GAN architectures and allows users to improve editing directions iteratively. In two user studies with 16 participants each, GANravel users were able to disentangle directions and outperformed the state-of-the-art direction discovery baselines in disentanglement performance. In the second user study, GANravel was used in a creative task of creating dog memes and was able to create high-quality edited images and GIFs.

cs.HC↗

Improving Workflow Integration with xPath: Design and Evaluation of a Human-AI Diagnosis System in Pathology

Recent developments in AI have provided assisting tools to support pathologists' diagnoses. However, it remains challenging to incorporate such tools into pathologists' practice; one main concern is AI's insufficient workflow integration with medical decisions. We observed pathologists' examination and discovered that the main hindering factor to integrate AI is its incompatibility with pathologists' workflow. To bridge the gap between pathologists and AI, we developed a human-AI collaborative diagnosis tool -- xPath -- that shares a similar examination process to that of pathologists, which can improve AI's integration into their routine examination. The viability of xPath is confirmed by a technical evaluation and work sessions with twelve medical professionals in pathology. This work identifies and addresses the challenge of incorporating AI models into pathology, which can offer first-hand knowledge about how HCI researchers can work with medical professionals side-by-side to bring technological advances to medical tasks towards practical applications.

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Discord Questions: A Computational Approach To Diversity Analysis in News Coverage

There are many potential benefits to news readers accessing diverse sources. Modern news aggregators do the hard work of organizing the news, offering readers a plethora of source options, but choosing which source to read remains challenging. We propose a new framework to assist readers in identifying source differences and gaining an understanding of news coverage diversity. The framework is based on the generation of Discord Questions: questions with a diverse answer pool, explicitly illustrating source differences. To assemble a prototype of the framework, we focus on two components: (1) discord question generation, the task of generating questions answered differently by sources, for which we propose an automatic scoring method, and create a model that improves performance from current question generation (QG) methods by 5%, (2) answer consolidation, the task of grouping answers to a question that are semantically similar, for which we collect data and repurpose a method that achieves 81% balanced accuracy on our realistic test set. We illustrate the framework's feasibility through a prototype interface. Even though model performance at discord QG still lags human performance by more than 15%, generated questions are judged to be more interesting than factoid questions and can reveal differences in the level of detail, sentiment, and reasoning of sources in news coverage.

cs.CL↗

Detecting Mitoses with a Convolutional Neural Network for MIDOG 2022 Challenge

This work presents a mitosis detection method with only one vanilla Convolutional Neural Network (CNN). Our method consists of two steps: given an image, we first apply a CNN using a sliding window technique to extract patches that have mitoses; we then calculate each extracted patch's class activation map to obtain the mitosis's precise location. To increase the model performance on high-domain-variance pathology images, we train the CNN with a data augmentation pipeline, a noise-tolerant loss that copes with unlabeled images, and a multi-rounded active learning strategy. In the MIDOG 2022 challenge, our approach, with an EfficientNet-b3 CNN model, achieved an overall F1 score of 0.7323 in the preliminary test phase, and 0.6847 in the final test phase (task 1). Our approach sheds light on the broader applicability of class activation maps for object detections in pathology images.

cs.CV↗

CrossA11y: Identifying Video Accessibility Issues via Cross-modal Grounding

Authors make their videos visually accessible by adding audio descriptions (AD), and auditorily accessible by adding closed captions (CC). However, creating AD and CC is challenging and tedious, especially for non-professional describers and captioners, due to the difficulty of identifying accessibility problems in videos. A video author will have to watch the video through and manually check for inaccessible information frame-by-frame, for both visual and auditory modalities. In this paper, we present CrossA11y, a system that helps authors efficiently detect and address visual and auditory accessibility issues in videos. Using cross-modal grounding analysis, CrossA11y automatically measures accessibility of visual and audio segments in a video by checking for modality asymmetries. CrossA11y then displays these segments and surfaces visual and audio accessibility issues in a unified interface, making it intuitive to locate, review, script AD/CC in-place, and preview the described and captioned video immediately. We demonstrate the effectiveness of CrossA11y through a lab study with 11 participants, comparing to existing baseline.

cs.HC↗

GANzilla: User-Driven Direction Discovery in Generative Adversarial Networks

Generative Adversarial Network (GAN) is widely adopted in numerous application areas, such as data preprocessing, image editing, and creativity support. However, GAN's 'black box' nature prevents non-expert users from controlling what data a model generates, spawning a plethora of prior work that focused on algorithm-driven approaches to extract editing directions to control GAN. Complementarily, we propose a GANzilla: a user-driven tool that empowers a user with the classic scatter/gather technique to iteratively discover directions to meet their editing goals. In a study with 12 participants, GANzilla users were able to discover directions that (i) edited images to match provided examples (closed-ended tasks) and that (ii) met a high-level goal, e.g., making the face happier, while showing diversity across individuals (open-ended tasks).

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Roman: Making Everyday Objects Robotically Manipulable with 3D-Printable Add-on Mechanisms

One important vision of robotics is to provide physical assistance by manipulating different everyday objects, e.g., hand tools, kitchen utensils. However, many objects designed for dexterous hand-control are not easily manipulable by a single robotic arm with a generic parallel gripper. Complementary to existing research on developing grippers and control algorithms, we present Roman, a suite of hardware design and software tool support for robotic engineers to create 3D printable mechanisms attached to everyday handheld objects, making them easier to be manipulated by conventional robotic arms. The Roman hardware comes with a versatile magnetic gripper that can snap on/off handheld objects and drive add-on mechanisms to perform tasks. Roman also provides software support to register and author control programs. To validate our approach, we designed and fabricated Roman mechanisms for 14 everyday objects/tasks presented within a design space and conducted expert interviews with robotic engineers indicating that Roman serves as a practical alternative for enabling robotic manipulation of everyday objects.

cs.RO↗

XAlgo: a Design Probe of Explaining Algorithms' Internal States via Question-Answering

Algorithms often appear as 'black boxes' to non-expert users. While prior work focuses on explainable representations and expert-oriented exploration, we propose and study an interactive approach using question answering to explain deterministic algorithms to non-expert users who need to understand the algorithms' internal states (e.g., students learning algorithms, operators monitoring robots, admins troubleshooting network routing). We construct XAlgo -- a formal model that first classifies the type of question based on a taxonomy and generates an answer based on a set of rules that extract information from representations of an algorithm's internal states, e.g., the pseudocode. A design probe in an algorithm learning scenario with 18 participants (9 for a Wizard-of-Oz XAlgo and 9 as a control group) reports findings and design implications based on what kinds of questions people ask, how well XAlgo responds, and what remain as challenges to bridge users' gulf of understanding algorithms.

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Lessons Learned from Designing an AI-Enabled Diagnosis Tool for Pathologists

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we involve AI usefully in physicians' diagnosis workflow given that most AI is still nascent and error-prone (e.g., in digital pathology)? To explore this question, we first propose a series of collaborative techniques to engage human pathologists with AI given AI's capabilities and limitations, based on which we prototype Impetus - a tool where an AI takes various degrees of initiatives to provide various forms of assistance to a pathologist in detecting tumors from histological slides. We summarize observations and lessons learned from a study with eight pathologists and discuss recommendations for future work on human-centered medical AI systems.

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