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Xiaojin Zhang

Publications and source records attributed to Xiaojin Zhang.

At least 55 records · Page 3Linked to original sources

MC-CoT: A Modular Collaborative CoT Framework for Zero-shot Medical-VQA with LLM and MLLM Integration

In recent advancements, multimodal large language models (MLLMs) have been fine-tuned on specific medical image datasets to address medical visual question answering (Med-VQA) tasks. However, this common approach of task-specific fine-tuning is costly and necessitates separate models for each downstream task, limiting the exploration of zero-shot capabilities. In this paper, we introduce MC-CoT, a modular cross-modal collaboration Chain-of-Thought (CoT) framework designed to enhance the zero-shot performance of MLLMs in Med-VQA by leveraging large language models (LLMs). MC-CoT improves reasoning and information extraction by integrating medical knowledge and task-specific guidance, where LLM provides various complex medical reasoning chains and MLLM provides various observations of medical images based on instructions of the LLM. Our experiments on datasets such as SLAKE, VQA-RAD, and PATH-VQA show that MC-CoT surpasses standalone MLLMs and various multimodality CoT frameworks in recall rate and accuracy. These findings highlight the importance of incorporating background information and detailed guidance in addressing complex zero-shot Med-VQA tasks.

cs.CV↗

Privacy in Large Language Models: Attacks, Defenses and Future Directions

The advancement of large language models (LLMs) has significantly enhanced the ability to effectively tackle various downstream NLP tasks and unify these tasks into generative pipelines. On the one hand, powerful language models, trained on massive textual data, have brought unparalleled accessibility and usability for both models and users. On the other hand, unrestricted access to these models can also introduce potential malicious and unintentional privacy risks. Despite ongoing efforts to address the safety and privacy concerns associated with LLMs, the problem remains unresolved. In this paper, we provide a comprehensive analysis of the current privacy attacks targeting LLMs and categorize them according to the adversary's assumed capabilities to shed light on the potential vulnerabilities present in LLMs. Then, we present a detailed overview of prominent defense strategies that have been developed to counter these privacy attacks. Beyond existing works, we identify upcoming privacy concerns as LLMs evolve. Lastly, we point out several potential avenues for future exploration.

cs.CL↗

VulDetectBench: Evaluating the Deep Capability of Vulnerability Detection with Large Language Models

Large Language Models (LLMs) have training corpora containing large amounts of program code, greatly improving the model's code comprehension and generation capabilities. However, sound comprehensive research on detecting program vulnerabilities, a more specific task related to code, and evaluating the performance of LLMs in this more specialized scenario is still lacking. To address common challenges in vulnerability analysis, our study introduces a new benchmark, VulDetectBench, specifically designed to assess the vulnerability detection capabilities of LLMs. The benchmark comprehensively evaluates LLM's ability to identify, classify, and locate vulnerabilities through five tasks of increasing difficulty. We evaluate the performance of 17 models (both open- and closed-source) and find that while existing models can achieve over 80% accuracy on tasks related to vulnerability identification and classification, they still fall short on specific, more detailed vulnerability analysis tasks, with less than 30% accuracy, making it difficult to provide valuable auxiliary information for professional vulnerability mining. Our benchmark effectively evaluates the capabilities of various LLMs at different levels in the specific task of vulnerability detection, providing a foundation for future research and improvements in this critical area of code security. VulDetectBench is publicly available at https://github.com/Sweetaroo/VulDetectBench.

cs.CR↗

A Framework for Evaluating Privacy-Utility Trade-off in Vertical Federated Learning

Federated learning (FL) has emerged as a practical solution to tackle data silo issues without compromising user privacy. One of its variants, vertical federated learning (VFL), has recently gained increasing attention as the VFL matches the enterprises' demands of leveraging more valuable features to build better machine learning models while preserving user privacy. Current works in VFL concentrate on developing a specific protection or attack mechanism for a particular VFL algorithm. In this work, we propose an evaluation framework that formulates the privacy-utility evaluation problem. We then use this framework as a guide to comprehensively evaluate a broad range of protection mechanisms against most of the state-of-the-art privacy attacks for three widely deployed VFL algorithms. These evaluations may help FL practitioners select appropriate protection mechanisms given specific requirements. Our evaluation results demonstrate that: the model inversion and most of the label inference attacks can be thwarted by existing protection mechanisms; the model completion (MC) attack is difficult to be prevented, which calls for more advanced MC-targeted protection mechanisms. Based on our evaluation results, we offer concrete advice on improving the privacy-preserving capability of VFL systems. The code is available at https://github.com/yankang18/Attack-Defense-VFL

cs.LG↗

The Grothendieck group of a triangulated category

We give a direct proof of the following known result: the Grothendieck group of a triangulated category with a silting subcategory is isomorphic to the split Grothendieck group of the silting subcategory. Moreover, we obtain its cluster-tilting analogue.

math.RT↗

A Hybrid Quantum Computing Pipeline for Real World Drug Discovery

Quantum computing, with its superior computational capabilities compared to classical approaches, holds the potential to revolutionize numerous scientific domains, including pharmaceuticals. However, the application of quantum computing for drug discovery has primarily been limited to proof-of-concept studies, which often fail to capture the intricacies of real-world drug development challenges. In this study, we diverge from conventional investigations by developing \rev{a hybrid} quantum computing pipeline tailored to address genuine drug design problems. Our approach underscores the application of quantum computation in drug discovery and propels it towards more scalable system. We specifically construct our versatile quantum computing pipeline to address two critical tasks in drug discovery: the precise determination of Gibbs free energy profiles for prodrug activation involving covalent bond cleavage, and the accurate simulation of covalent bond interactions. This work serves as a pioneering effort in benchmarking quantum computing against veritable scenarios encountered in drug design, especially the covalent bonding issue present in both of the case studies, thereby transitioning from theoretical models to tangible applications. Our results demonstrate the potential of a quantum computing pipeline for integration into real world drug design workflows.

physics.chem-ph↗

Theoretical Analysis of Privacy Leakage in Trustworthy Federated Learning: A Perspective from Linear Algebra and Optimization Theory

Federated learning has emerged as a promising paradigm for collaborative model training while preserving data privacy. However, recent studies have shown that it is vulnerable to various privacy attacks, such as data reconstruction attacks. In this paper, we provide a theoretical analysis of privacy leakage in federated learning from two perspectives: linear algebra and optimization theory. From the linear algebra perspective, we prove that when the Jacobian matrix of the batch data is not full rank, there exist different batches of data that produce the same model update, thereby ensuring a level of privacy. We derive a sufficient condition on the batch size to prevent data reconstruction attacks. From the optimization theory perspective, we establish an upper bound on the privacy leakage in terms of the batch size, the distortion extent, and several other factors. Our analysis provides insights into the relationship between privacy leakage and various aspects of federated learning, offering a theoretical foundation for designing privacy-preserving federated learning algorithms.

cs.CR↗

A Unified Learn-to-Distort-Data Framework for Privacy-Utility Trade-off in Trustworthy Federated Learning

In this paper, we first give an introduction to the theoretical basis of the privacy-utility equilibrium in federated learning based on Bayesian privacy definitions and total variation distance privacy definitions. We then present the \textit{Learn-to-Distort-Data} framework, which provides a principled approach to navigate the privacy-utility equilibrium by explicitly modeling the distortion introduced by the privacy-preserving mechanism as a learnable variable and optimizing it jointly with the model parameters. We demonstrate the applicability of our framework to a variety of privacy-preserving mechanisms on the basis of data distortion and highlight its connections to related areas such as adversarial training, input robustness, and unlearnable examples. These connections enable leveraging techniques from these areas to design effective algorithms for privacy-utility equilibrium in federated learning under the \textit{Learn-to-Distort-Data} framework.

cs.LG↗

Beyond ESM2: Graph-Enhanced Protein Sequence Modeling with Efficient Clustering

Proteins are essential to life's processes, underpinning evolution and diversity. Advances in sequencing technology have revealed millions of proteins, underscoring the need for sophisticated pre-trained protein models for biological analysis and AI development. Facebook's ESM2, the most advanced protein language model to date, leverages a masked prediction task for unsupervised learning, crafting amino acid representations with notable biochemical accuracy. Yet, it lacks in delivering functional protein insights, signaling an opportunity for enhancing representation quality.Our study addresses this gap by incorporating protein family classification into ESM2's training.This approach, augmented with Community Propagation-Based Clustering Algorithm, improves global protein representations, while a contextual prediction task fine-tunes local amino acid accuracy. Significantly, our model achieved state-of-the-art results in several downstream experiments, demonstrating the power of combining global and local methodologies to substantially boost protein representation quality.

q-bio.BM↗

Grounding Foundation Models through Federated Transfer Learning: A General Framework

Foundation Models (FMs) such as GPT-4 encoded with vast knowledge and powerful emergent abilities have achieved remarkable success in various natural language processing and computer vision tasks. Grounding FMs by adapting them to domain-specific tasks or augmenting them with domain-specific knowledge enables us to exploit the full potential of FMs. However, grounding FMs faces several challenges, stemming primarily from constrained computing resources, data privacy, model heterogeneity, and model ownership. Federated Transfer Learning (FTL), the combination of federated learning and transfer learning, provides promising solutions to address these challenges. In recent years, the need for grounding FMs leveraging FTL, coined FTL-FM, has arisen strongly in both academia and industry. Motivated by the strong growth in FTL-FM research and the potential impact of FTL-FM on industrial applications, we propose an FTL-FM framework that formulates problems of grounding FMs in the federated learning setting, construct a detailed taxonomy based on the FTL-FM framework to categorize state-of-the-art FTL-FM works, and comprehensively overview FTL-FM works based on the proposed taxonomy. We also establish correspondences between FTL-FM and conventional phases of adapting FM so that FM practitioners can align their research works with FTL-FM. In addition, we overview advanced efficiency-improving and privacy-preserving techniques because efficiency and privacy are critical concerns in FTL-FM. Last, we discuss opportunities and future research directions of FTL-FM.

cs.LG↗

Towards Achieving Near-optimal Utility for Privacy-Preserving Federated Learning via Data Generation and Parameter Distortion

Federated learning (FL) enables participating parties to collaboratively build a global model with boosted utility without disclosing private data information. Appropriate protection mechanisms have to be adopted to fulfill the requirements in preserving \textit{privacy} and maintaining high model \textit{utility}. The nature of the widely-adopted protection mechanisms including \textit{Randomization Mechanism} and \textit{Compression Mechanism} is to protect privacy via distorting model parameter. We measure the utility via the gap between the original model parameter and the distorted model parameter. We want to identify under what general conditions privacy-preserving federated learning can achieve near-optimal utility via data generation and parameter distortion. To provide an avenue for achieving near-optimal utility, we present an upper bound for utility loss, which is measured using two main terms called variance-reduction and model parameter discrepancy separately. Our analysis inspires the design of appropriate protection parameters for the protection mechanisms to achieve near-optimal utility and meet the privacy requirements simultaneously. The main techniques for the protection mechanism include parameter distortion and data generation, which are generic and can be applied extensively. Furthermore, we provide an upper bound for the trade-off between privacy and utility, \blue{which together with the lower bound provided by no free lunch theorem in federated learning (\cite{zhang2022no}) form the conditions for achieving optimal trade-off.

cs.LG↗

A Game-theoretic Framework for Privacy-preserving Federated Learning

In federated learning, benign participants aim to optimize a global model collaboratively. However, the risk of \textit{privacy leakage} cannot be ignored in the presence of \textit{semi-honest} adversaries. Existing research has focused either on designing protection mechanisms or on inventing attacking mechanisms. While the battle between defenders and attackers seems never-ending, we are concerned with one critical question: is it possible to prevent potential attacks in advance? To address this, we propose the first game-theoretic framework that considers both FL defenders and attackers in terms of their respective payoffs, which include computational costs, FL model utilities, and privacy leakage risks. We name this game the federated learning privacy game (FLPG), in which neither defenders nor attackers are aware of all participants' payoffs. To handle the \textit{incomplete information} inherent in this situation, we propose associating the FLPG with an \textit{oracle} that has two primary responsibilities. First, the oracle provides lower and upper bounds of the payoffs for the players. Second, the oracle acts as a correlation device, privately providing suggested actions to each player. With this novel framework, we analyze the optimal strategies of defenders and attackers. Furthermore, we derive and demonstrate conditions under which the attacker, as a rational decision-maker, should always follow the oracle's suggestion \textit{not to attack}.

cs.LG↗

A Meta-learning Framework for Tuning Parameters of Protection Mechanisms in Trustworthy Federated Learning

Trustworthy Federated Learning (TFL) typically leverages protection mechanisms to guarantee privacy. However, protection mechanisms inevitably introduce utility loss or efficiency reduction while protecting data privacy. Therefore, protection mechanisms and their parameters should be carefully chosen to strike an optimal tradeoff between \textit{privacy leakage}, \textit{utility loss}, and \textit{efficiency reduction}. To this end, federated learning practitioners need tools to measure the three factors and optimize the tradeoff between them to choose the protection mechanism that is most appropriate to the application at hand. Motivated by this requirement, we propose a framework that (1) formulates TFL as a problem of finding a protection mechanism to optimize the tradeoff between privacy leakage, utility loss, and efficiency reduction and (2) formally defines bounded measurements of the three factors. We then propose a meta-learning algorithm to approximate this optimization problem and find optimal protection parameters for representative protection mechanisms, including Randomization, Homomorphic Encryption, Secret Sharing, and Compression. We further design estimation algorithms to quantify these found optimal protection parameters in a practical horizontal federated learning setting and provide a theoretical analysis of the estimation error.

cs.LG↗

CauESC: A Causal Aware Model for Emotional Support Conversation

Emotional Support Conversation aims at reducing the seeker's emotional distress through supportive response. Existing approaches have two limitations: (1) They ignore the emotion causes of the distress, which is important for fine-grained emotion understanding; (2) They focus on the seeker's own mental state rather than the emotional dynamics during interaction between speakers. To address these issues, we propose a novel framework CauESC, which firstly recognizes the emotion causes of the distress, as well as the emotion effects triggered by the causes, and then understands each strategy of verbal grooming independently and integrates them skillfully. Experimental results on the benchmark dataset demonstrate the effectiveness of our approach and show the benefits of emotion understanding from cause to effect and independent-integrated strategy modeling.

cs.CL↗

Applications of Gorenstein projective $τ$-rigid modules

We first introduce the notion of $CM$-$τ$-tilting free algebras as the generalization of $CM$-free algebras and show the homological properties of $CM$-$τ$-tilting free algebras. Then we give a bijection between Gorenstein projective $τ$-rigid modules and certain modules by using an equivalence established by Kong and Zhang. Finally, we give a partial answer to Tachikawa's first conjecture by using Gorenstein projective $τ$-rigid modules.

math.RT↗

Improved Algorithm for Permutation Testing

For a permutation $π: [K]\rightarrow [K]$, a sequence $f: \{1,2,\cdots, n\}\rightarrow \mathbb R$ contains a $π$-pattern of size $K$, if there is a sequence of indices $(i_1, i_2, \cdots, i_K)$ ($i_1<i_2<\cdots<i_K$), satisfying that $f(i_a)<f(i_b)$ if $π(a)<π(b)$, for $a,b\in [K]$. Otherwise, $f$ is referred to as $π$-free. For the special case where $π= (1,2,\cdots, K)$, it is referred to as the monotone pattern. \cite{newman2017testing} initiated the study of testing $π$-freeness with one-sided error. They focused on two specific problems, testing the monotone permutations and the $(1,3,2)$ permutation. For the problem of testing monotone permutation $(1,2,\cdots,K)$, \cite{ben2019finding} improved the $(\log n)^{O(K^2)}$ non-adaptive query complexity of \cite{newman2017testing} to $O((\log n)^{\lfloor \log_{2} K\rfloor})$. Further, \cite{ben2019optimal} proposed an adaptive algorithm with $O(\log n)$ query complexity. However, no progress has yet been made on the problem of testing $(1,3,2)$-freeness. In this work, we present an adaptive algorithm for testing $(1,3,2)$-freeness. The query complexity of our algorithm is $O(ε^{-2}\log^4 n)$, which significantly improves over the $O(ε^{-7}\log^{26}n)$-query adaptive algorithm of \cite{newman2017testing}. This improvement is mainly achieved by the proposal of a new structure embedded in the patterns.

cs.DS↗

K-ESConv: Knowledge Injection for Emotional Support Dialogue Systems via Prompt Learning

Automatic psychological counseling requires mass of professional knowledge that can be found in online counseling forums. Motivated by this, we propose K-ESConv, a novel prompt learning based knowledge injection method for emotional support dialogue system, transferring forum knowledge to response generation. We evaluate our model on an emotional support dataset ESConv, where the model retrieves and incorporates knowledge from external professional emotional Q\&A forum. Experiment results show that the proposed method outperforms existing baselines on both automatic evaluation and human evaluation, which shows that our approach significantly improves the correlation and diversity of responses and provides more comfort and better suggestion for the seeker.

cs.CL↗

Toward the Tradeoffs between Privacy, Fairness and Utility in Federated Learning

Federated Learning (FL) is a novel privacy-protection distributed machine learning paradigm that guarantees user privacy and prevents the risk of data leakage due to the advantage of the client's local training. Researchers have struggled to design fair FL systems that ensure fairness of results. However, the interplay between fairness and privacy has been less studied. Increasing the fairness of FL systems can have an impact on user privacy, while an increase in user privacy can affect fairness. In this work, on the client side, we use fairness metrics, such as Demographic Parity (DemP), Equalized Odds (EOs), and Disparate Impact (DI), to construct the local fair model. To protect the privacy of the client model, we propose a privacy-protection fairness FL method. The results show that the accuracy of the fair model with privacy increases because privacy breaks the constraints of the fairness metrics. In our experiments, we conclude the relationship between privacy, fairness and utility, and there is a tradeoff between these.

cs.LG↗