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Xiaoli Yang

Publications and source records attributed to Xiaoli Yang.

8 recordsLinked to original sources

Harmonic-Aware Transformer for Real-Time Catheter Localization in Interventional Procedures of Magnetic Particle Imaging

Magnetic particle imaging (MPI) enables real-time, radiation-free tracking of magnetic nanoparticle-coated instruments, making it highly suitable for interventional procedures. This study proposes a harmonic-aware transformer framework that directly predicts catheter tip positions from raw MPI voltage signals, eliminating the need for image reconstruction and reducing computational latency. The framework incorporates frequency-domain preprocessing to isolate the 2nd to 8th drive-field harmonics, enhancing the signal-to-noise ratio while preserving motion-relevant features. A transformer architecture with six encoder layers and eight attention heads is employed to learn spatio-temporal dependencies across the three receive axes (x, y, z) for accurate three-dimensional position estimation. The model is trained on simulated MPI signals and evaluated on real in vitro datasets under standard, bending, and heartbeat-like motion conditions. The proposed method achieves sub-millimeter localization accuracy, with a minimum L2 error of 0.103 +/- 0.092 mm and mean absolute errors (MAEs) of 0.039 +/- 0.046 mm, 0.054 +/- 0.049 mm, and 0.060 +/- 0.044 mm along the (x, y, z) axes, respectively, for the bending dataset. Across all datasets, the MAE ranges from 0.165 mm to 0.655 mm, demonstrating consistent performance. The optimized inference achieves a latency of 0.55 ms per frame and a throughput of approximately 1800 frames per second, confirming real-time capability. Compared with conventional MPI-guided approaches relying on image reconstruction, the proposed framework provides improved accuracy, reduced latency, and enhanced robustness under complex motion conditions. These results highlight the potential of harmonic-aware transformer models as efficient and scalable solutions for real-time catheter localization in interventional MPI.

physics.med-ph

Brain-CLIPLM: Semantic Compression for EEG-to-Text Decoding

Decoding natural language from non-invasive electroencephalography (EEG) remains constrained by low signal-to-noise ratio and limited information bandwidth. This raises a central question: can sentence-level language be reliably recovered from such signals? Under realistic information constraints, this direct-recovery assumption may be too strong. We introduce a semantic compression hypothesis: non-invasive EEG may preserve recoverable semantic anchors rather than the full lexical--syntactic form of a sentence. From this perspective, direct sentence reconstruction is overly fine-grained relative to the recoverable information scale of EEG. To address this mismatch, we propose Brain-CLIPLM, a two-stage framework that decomposes EEG-to-text decoding into semantic-anchor recovery and anchor-guided sentence reconstruction. Stage 1 uses contrastive learning to align word-level EEG evidence with a fixed keyword vocabulary and recover ordered semantic anchors. Stage 2 uses a retrieval-grounded large language model with chain-of-thought reasoning prompts to reconstruct sentence meaning from these anchors, following a granularity matching principle that aligns decoding complexity with the recoverable neural information scale. On the combined Zurich Cognitive Language Processing (ZuCo) benchmark, Brain-CLIPLM achieves 67.6\% Top-5 and 85.0\% Top-25 sentence retrieval accuracy, with the strongest performance at intermediate anchor granularity. Control analyses show that EEG-derived anchors carry sentence-specific information beyond language-model priors. Within the constrained ZuCo sentence pool and fixed keyword-vocabulary settings, these findings suggest that EEG-to-text decoding is better framed as recovering compressed semantic content before anchor-guided sentence reconstruction.

cs.CL

A Generative Foundation Model for Chest Radiography

The scarcity of well-annotated diverse medical images is a major hurdle for developing reliable AI models in healthcare. Substantial technical advances have been made in generative foundation models for natural images. Here we develop `ChexGen', a generative vision-language foundation model that introduces a unified framework for text-, mask-, and bounding box-guided synthesis of chest radiographs. Built upon the latent diffusion transformer architecture, ChexGen was pretrained on the largest curated chest X-ray dataset to date, consisting of 960,000 radiograph-report pairs. ChexGen achieves accurate synthesis of radiographs through expert evaluations and quantitative metrics. We demonstrate the utility of ChexGen for training data augmentation and supervised pretraining, which led to performance improvements across disease classification, detection, and segmentation tasks using a small fraction of training data. Further, our model enables the creation of diverse patient cohorts that enhance model fairness by detecting and mitigating demographic biases. Our study supports the transformative role of generative foundation models in building more accurate, data-efficient, and equitable medical AI systems.

cs.CV

CTC: The Composite Task Challenge for Cooperative Multi-Agent Reinforcement Learning

The critical role of division of labor (DOL) in enhancing cooperation is well-recognized in real-world applications. Consequently, many cooperative multi-agent reinforcement learning (MARL) methods have incorporated DOL mechanisms to improve cooperation among agents. However, the lack of benchmark tasks specifically designed to evaluate and promote DOL and cooperation has limited the effective development and deployment of such mechanisms in cooperative MARL. This gap between current cooperative MARL methods and practical applications underscores the need for evaluation tasks that explicitly require DOL and cooperation. To address this gap, we propose the Composite Tasks Challenge (CTC), a suite of tasks explicitly designed to require both DOL and cooperation for successful task completion. The CTC tasks are constructed based on two core design principles: 1) DOL is a necessary condition for task success; 2) Failure in any atomic subtask results in failure of the overall task. The first principle emphasizes the necessity of DOL, while the second enforces the importance of cooperation, making both components essential for success in CTC tasks. We evaluate nine representative cooperative MARL methods on the proposed CTC tasks. Experimental results show that all methods consistently achieve zero test winning rates across all CTC tasks, highlighting the challenge of CTC tasks and the limitations of current methods. To facilitate future research, we also introduce a guiding solution that achieves non-zero test winning rates on all tasks, thereby demonstrating the solvability of the CTC tasks. However, the performance of this guiding solution remains suboptimal, further underscoring the value of CTC tasks as a challenging and meaningful testbed for advancing cooperative MARL research.

cs.LG

ReXrank: A Public Leaderboard for AI-Powered Radiology Report Generation

AI-driven models have demonstrated significant potential in automating radiology report generation for chest X-rays. However, there is no standardized benchmark for objectively evaluating their performance. To address this, we present ReXrank, https://rexrank.ai, a public leaderboard and challenge for assessing AI-powered radiology report generation. Our framework incorporates ReXGradient, the largest test dataset consisting of 10,000 studies, and three public datasets (MIMIC-CXR, IU-Xray, CheXpert Plus) for report generation assessment. ReXrank employs 8 evaluation metrics and separately assesses models capable of generating only findings sections and those providing both findings and impressions sections. By providing this standardized evaluation framework, ReXrank enables meaningful comparisons of model performance and offers crucial insights into their robustness across diverse clinical settings. Beyond its current focus on chest X-rays, ReXrank's framework sets the stage for comprehensive evaluation of automated reporting across the full spectrum of medical imaging.

cs.CV

LymphoML: An interpretable artificial intelligence-based method identifies morphologic features that correlate with lymphoma subtype

The accurate classification of lymphoma subtypes using hematoxylin and eosin (H&E)-stained tissue is complicated by the wide range of morphological features these cancers can exhibit. We present LymphoML - an interpretable machine learning method that identifies morphologic features that correlate with lymphoma subtypes. Our method applies steps to process H&E-stained tissue microarray cores, segment nuclei and cells, compute features encompassing morphology, texture, and architecture, and train gradient-boosted models to make diagnostic predictions. LymphoML's interpretable models, developed on a limited volume of H&E-stained tissue, achieve non-inferior diagnostic accuracy to pathologists using whole-slide images and outperform black box deep-learning on a dataset of 670 cases from Guatemala spanning 8 lymphoma subtypes. Using SHapley Additive exPlanation (SHAP) analysis, we assess the impact of each feature on model prediction and find that nuclear shape features are most discriminative for DLBCL (F1-score: 78.7%) and classical Hodgkin lymphoma (F1-score: 74.5%). Finally, we provide the first demonstration that a model combining features from H&E-stained tissue with features from a standardized panel of 6 immunostains results in a similar diagnostic accuracy (85.3%) to a 46-stain panel (86.1%).

cs.LG

Depth Estimation by Combining Binocular Stereo and Monocular Structured-Light

It is well known that the passive stereo system cannot adapt well to weak texture objects, e.g., white walls. However, these weak texture targets are very common in indoor environments. In this paper, we present a novel stereo system, which consists of two cameras (an RGB camera and an IR camera) and an IR speckle projector. The RGB camera is used both for depth estimation and texture acquisition. The IR camera and the speckle projector can form a monocular structured-light (MSL) subsystem, while the two cameras can form a binocular stereo subsystem. The depth map generated by the MSL subsystem can provide external guidance for the stereo matching networks, which can improve the matching accuracy significantly. In order to verify the effectiveness of the proposed system, we build a prototype and collect a test dataset in indoor scenes. The evaluation results show that the Bad 2.0 error of the proposed system is 28.2% of the passive stereo system when the network RAFT is used. The dataset and trained models are available at https://github.com/YuhuaXu/MonoStereoFusion.

cs.CV

Bilateral Grid Learning for Stereo Matching Networks

Real-time performance of stereo matching networks is important for many applications, such as automatic driving, robot navigation and augmented reality (AR). Although significant progress has been made in stereo matching networks in recent years, it is still challenging to balance real-time performance and accuracy. In this paper, we present a novel edge-preserving cost volume upsampling module based on the slicing operation in the learned bilateral grid. The slicing layer is parameter-free, which allows us to obtain a high quality cost volume of high resolution from a low-resolution cost volume under the guide of the learned guidance map efficiently. The proposed cost volume upsampling module can be seamlessly embedded into many existing stereo matching networks, such as GCNet, PSMNet, and GANet. The resulting networks are accelerated several times while maintaining comparable accuracy. Furthermore, we design a real-time network (named BGNet) based on this module, which outperforms existing published real-time deep stereo matching networks, as well as some complex networks on the KITTI stereo datasets. The code is available at https://github.com/YuhuaXu/BGNet.

cs.CV