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Xiaoming Guo

Publications and source records attributed to Xiaoming Guo.

2 recordsLinked to original sources

Focal-point scanning for dose delivery and optimization with focused laser-accelerated very-high-energy electron beams

Focused very-high-energy electron (VHEE) beams can produce localized dose enhancement at selected depths, but irradiation of a finite target requires coordinated control of multiple focal positions, incidence directions, and beam weights while limiting exposure of nearby organs at risk (OARs). We present Focal-Point Scanning (FPS), a dose delivery and optimization method developed for laser wakefield accelerator (LWFA)-driven VHEE beams. The method is based on a two-dipole focusing system that produces single-plane beam convergence and allows the focal position to be varied by changing the magnetic field strength. FPS distributes focal points throughout the planning target volume and determines focal-point-specific incidence sectors according to the geometry of nearby critical OARs. The method was evaluated using the AAPM TG119 C-shape benchmark and one previously treated lung radiotherapy case. At matched target coverage, FPS reduced the TG119 Core mean dose by approximately one half relative to parallel VHEE and intensity-modulated x-ray plans, approaching the single-field proton pencil-beam-scanning reference. In the lung case, FPS maintained target coverage comparable to the clinical volumetric modulated arc therapy reference while reducing the mean dose to every evaluated OAR; spinal-cord mean and maximum doses decreased by 93.2% and 87.2%, respectively. The evaluated OAR mean doses varied little across rms energy spreads of 0 to 10% and for a flat-top electron spectrum spanning 150 to 250 MeV. These results demonstrate that focal-point-specific angular selection can translate focused-beam physics into effective OAR sparing and support FPS as a planning strategy for broadband LWFA-VHEE radiotherapy.

physics.med-ph

Comparative study of equilibrium and non-equilibrium predictions by different models for a hypersonic cone at high-altitude

Targeting a cone with the half-angle as 10-deg at M = 27 and H = 72 km, simulations were conducted comparatively to analyze the predictions by different equilibrium and non-equilibrium gas models. Following validation and grid studies, systematic comparisons on aerodynamic performance, flow structures, and characteristic distributions were performed. The key findings are: (1) While the overall flow structures are broadly similar, discrepancies exist in the features at the base locations, e.g., the diverse high-temperature distributions. Notably, the vibrational temperatures distribute differently under slip and non-slip boundary conditions near the wall; (2) The equilibrium gas model predicts higher drag coefficient, wall heat flux, and skin friction than those of non-equilibrium models. Predictions also vary among the non-equilibrium models themselves. Specifically, compared to the three-temperature model, the one- and two-temperature models predict larger drag coefficients with the relative difference exceeding 5%. Nevertheless, the results from the three-temperature model with and without slip conditions are largely consistent; (3) The disparities between equilibrium and non-equilibrium characteristics are primarily manifested in the shock layer and wake regions. Within these regions, the overall temperature for the equilibrium gas is lower than that for the non-equilibrium cases, while in the latter specific non-equilibrium features are distinctly exhibited, e.g., the translational-rotational temperature is generally higher than that from the one-temperature model, and the vibrational-electronic temperature shows the opposite trend. Notably, in the slip flow within the three-temperature model, the translational-rotational temperature is higher and, particularly, the vibrational temperature is even larger than counterparts of the non-slip flows near the wall and base center line.

physics.flu-dyn