arXiv subjects

Xiaoming Zhang

Publications and source records attributed to Xiaoming Zhang.

At least 37 records · Page 2Linked to original sources

arXiv2026

Mixture of Disentangled Experts with Missing Modalities for Robust Multimodal Sentiment Analysis

Multimodal Sentiment Analysis (MSA) integrates multiple modalities to infer human sentiment, but real-world noise often leads to missing or corrupted data. However, existing feature-disentangled methods struggle to handle the internal variations of heterogeneous information under uncertain missingness, making it difficult to learn effective multimodal representations from degraded modalities. To address this issue, we propose DERL, a Disentangled Expert Representation Learning framework for robust MSA. Specifically, DERL employs hybrid experts to adaptively disentangle multimodal inputs into orthogonal private and shared representation spaces. A multi-level reconstruction strategy is further developed to provide collaborative supervision, enhancing both the expressiveness and robustness of the learned representations. Finally, the disentangled features act as modality experts with distinct roles to generate importance-aware fusion results. Extensive experiments on two MSA benchmarks demonstrate that DERL outperforms state-of-the-art methods under various missing-modality conditions. For instance, our method achieves improvements of 2.47% in Acc-2 and 2.25% in MAE on MOSI under intra-modal missingness.

cs.MM↗

arXiv2026

The R2Pub Telescopes for Surveying: An Overview and Performance Evaluation of the System

The R2Pub telescope, built by the Beijing Planetarium, is a 60 cm equatorial binocular telescope located at the Daocheng site of Yunnan Observatories in China, at an altitude of about 4700 m. This paper presents an overview of the R2Pub telescope system, including its design, instrumentation, and survey capabilities, and reports an initial evaluation of its system performance. R2Pub is a prime-focus binocular system, with each optical tube covering a field of view of approximately 18 square degrees. It is designed to detect a wide range of transient and variable sources in the local universe, such as variable stars, eclipsing binaries, supernovae, gamma-ray burst afterglows, tidal disruption events, active galactic nuclei, and other unknown transients. The observatory infrastructure, including the dome, equatorial mount, optical tubes, and associated subsystems, has been fully constructed and installed, and the system has entered the commissioning phase. Benefiting from the high-altitude location, good seeing conditions, and dark sky background at the Daocheng site, performance tests during commissioning show that the R2Pub system can reach a 5-sigma limiting magnitude of about 18.7 mag in the Pan-STARRS r' band with a 60 s exposure. Ongoing observations with R2Pub are expected to contribute to studies of variable and transient phenomena and to enhance public outreach in astronomy. The binocular design enables simultaneous dual-band observations, providing instantaneous color information for transient sources and improving the classification and physical characterization of their properties and evolution.

astro-ph.IM↗

arXiv2026

TF-Mamba: Text-enhanced Fusion Mamba with Missing Modalities for Robust Multimodal Sentiment Analysis

Multimodal Sentiment Analysis (MSA) with missing modalities has attracted increasing attention recently. While current Transformer-based methods leverage dense text information to maintain model robustness, their quadratic complexity hinders efficient long-range modeling and multimodal fusion. To this end, we propose a novel and efficient Text-enhanced Fusion Mamba (TF-Mamba) framework for robust MSA with missing modalities. Specifically, a Text-aware Modality Enhancement (TME) module aligns and enriches non-text modalities, while reconstructing the missing text semantics. Moreover, we develop Text-based Context Mamba (TC-Mamba) to capture intra-modal contextual dependencies under text collaboration. Finally, Text-guided Query Mamba (TQ-Mamba) queries text-guided multimodal information and learns joint representations for sentiment prediction. Extensive experiments on three MSA datasets demonstrate the effectiveness and efficiency of the proposed method under missing modality scenarios. Our code is available at https://github.com/codemous/TF-Mamba.

cs.MM↗

arXiv2025

Non-Contrast CT Esophageal Varices Grading through Clinical Prior-Enhanced Multi-Organ Analysis

Esophageal varices (EV) represent a critical complication of portal hypertension, affecting approximately 60% of cirrhosis patients with a significant bleeding risk of ~30%. While traditionally diagnosed through invasive endoscopy, non-contrast computed tomography (NCCT) presents a potential non-invasive alternative that has yet to be fully utilized in clinical practice. We present Multi-Organ-COhesion Network++ (MOON++), a novel multimodal framework that enhances EV assessment through comprehensive analysis of NCCT scans. Inspired by clinical evidence correlating organ volumetric relationships with liver disease severity, MOON++ synthesizes imaging characteristics of the esophagus, liver, and spleen through multimodal learning. We evaluated our approach using 1,631 patients, those with endoscopically confirmed EV were classified into four severity grades. Validation in 239 patient cases and independent testing in 289 cases demonstrate superior performance compared to conventional single organ methods, achieving an AUC of 0.894 versus 0.803 for the severe grade EV classification (G3 versus =G2 versus <G2). We conducted a reader study involving experienced radiologists to further validate the performance of MOON++. To our knowledge, MOON++ represents the first comprehensive multi-organ NCCT analysis framework incorporating clinical knowledge priors for EV assessment, potentially offering a promising non-invasive diagnostic alternative.

cs.CV↗

arXiv2025

Life-Code: Central Dogma Modeling with Multi-Omics Sequence Unification

The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. Although modern biological pre-trained models have achieved great success in analyzing these macromolecules individually, their interconnected nature remains underexplored. This paper follows the guidance of the central dogma to redesign both the data and model pipeline and offers a comprehensive framework, Life-Code, that spans different biological functions. As for data flow, we propose a unified pipeline to integrate multi-omics data by reverse-transcribing RNA and reverse-translating amino acids into nucleotide-based sequences. As for the model, we design a codon tokenizer and a hybrid long-sequence architecture to encode the interactions between coding and non-coding regions through masked modeling pre-training. To model the translation and folding process with coding sequences, Life-Code learns protein structures of the corresponding amino acids by knowledge distillation from off-the-shelf protein language models. Such designs enable Life-Code to capture complex interactions within genetic sequences, providing a more comprehensive understanding of multi-omics with the central dogma. Extensive experiments show that Life-Code achieves state-of-the-art results on various tasks across three omics, highlighting its potential for advancing multi-omics analysis and interpretation.

cs.LG↗

arXiv2025

MergeDNA: Context-aware Genome Modeling with Dynamic Tokenization through Token Merging

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently designed DNA tokenizers, existing approaches with naive masked language modeling pre-training often fail to adapt to the varying complexities of genomic sequences. Leveraging Token Merging techniques, this paper introduces a hierarchical architecture that jointly optimizes a dynamic genomic tokenizer and latent Transformers with context-aware pre-training tasks. As for network structures, the tokenization module automatically chunks adjacent bases into words by stacking multiple layers of the differentiable token merging blocks with local-window constraints, then a Latent Encoder captures the global context of these merged words by full-attention blocks. Symmetrically employing a Latent Decoder and a Local Decoder, MergeDNA learns with two pre-training tasks: Merged Token Reconstruction simultaneously trains the dynamic tokenization module and adaptively filters important tokens, while Adaptive Masked Token Modeling learns to predict these filtered tokens to capture informative contents. Extensive experiments show that MergeDNA achieves superior performance on three popular DNA benchmarks and several multi-omics tasks with fine-tuning or zero-shot evaluation, outperforming typical tokenization methods and large-scale DNA foundation models.

q-bio.GN↗

arXiv2025

An Energy-Efficient Edge Coprocessor for Neural Rendering with Explicit Data Reuse Strategies

Neural radiance fields (NeRF) have transformed 3D reconstruction and rendering, facilitating photorealistic image synthesis from sparse viewpoints. This work introduces an explicit data reuse neural rendering (EDR-NR) architecture, which reduces frequent external memory accesses (EMAs) and cache misses by exploiting the spatial locality from three phases, including rays, ray packets (RPs), and samples. The EDR-NR architecture features a four-stage scheduler that clusters rays on the basis of Z-order, prioritize lagging rays when ray divergence happens, reorders RPs based on spatial proximity, and issues samples out-of-orderly (OoO) according to the availability of on-chip feature data. In addition, a four-tier hierarchical RP marching (HRM) technique is integrated with an axis-aligned bounding box (AABB) to facilitate spatial skipping (SS), reducing redundant computations and improving throughput. Moreover, a balanced allocation strategy for feature storage is proposed to mitigate SRAM bank conflicts. Fabricated using a 40 nm process with a die area of 10.5 mmX, the EDR-NR chip demonstrates a 2.41X enhancement in normalized energy efficiency, a 1.21X improvement in normalized area efficiency, a 1.20X increase in normalized throughput, and a 53.42% reduction in on-chip SRAM consumption compared to state-of-the-art accelerators.

eess.IV↗

arXiv2025

Attack the Messages, Not the Agents: A Multi-round Adaptive Stealthy Tampering Framework for LLM-MAS

Large language model-based multi-agent systems (LLM-MAS) effectively accomplish complex and dynamic tasks through inter-agent communication, but this reliance introduces substantial safety vulnerabilities. Existing attack methods targeting LLM-MAS either compromise agent internals or rely on direct and overt persuasion, which limit their effectiveness, adaptability, and stealthiness. In this paper, we propose MAST, a Multi-round Adaptive Stealthy Tampering framework designed to exploit communication vulnerabilities within the system. MAST integrates Monte Carlo Tree Search with Direct Preference Optimization to train an attack policy model that adaptively generates effective multi-round tampering strategies. Furthermore, to preserve stealthiness, we impose dual semantic and embedding similarity constraints during the tampering process. Comprehensive experiments across diverse tasks, communication architectures, and LLMs demonstrate that MAST consistently achieves high attack success rates while significantly enhancing stealthiness compared to baselines. These findings highlight the effectiveness, stealthiness, and adaptability of MAST, underscoring the need for robust communication safeguards in LLM-MAS.

cs.CR↗

arXiv2025

Hybrid CNN-Mamba Enhancement Network for Robust Multimodal Sentiment Analysis

Multimodal Sentiment Analysis (MSA) with missing modalities has recently attracted increasing attention. Although existing research mainly focuses on designing complex model architectures to handle incomplete data, it still faces significant challenges in effectively aligning and fusing multimodal information. In this paper, we propose a novel framework called the Hybrid CNN-Mamba Enhancement Network (HCMEN) for robust multimodal sentiment analysis under missing modality conditions. HCMEN is designed around three key components: (1) hierarchical unimodal modeling, (2) cross-modal enhancement and alignment, and (3) multimodal mix-up fusion. First, HCMEN integrates the strengths of Convolutional Neural Network (CNN) for capturing local details and the Mamba architecture for modeling global contextual dependencies across different modalities. Furthermore, grounded in the principle of Mutual Information Maximization, we introduce a cross-modal enhancement mechanism that generates proxy modalities from mixed token-level representations and learns fine-grained token-level correspondences between modalities. The enhanced unimodal features are then fused and passed through the CNN-Mamba backbone, enabling local-to-global cross-modal interaction and comprehensive multimodal integration. Extensive experiments on two benchmark MSA datasets demonstrate that HCMEN consistently outperforms existing state-of-the-art methods, achieving superior performance across various missing modality scenarios. The code will be released publicly in the near future.

cs.MM↗

arXiv2025

EnTao-GPM: DNA Foundation Model for Predicting the Germline Pathogenic Mutations

Distinguishing pathogenic mutations from benign polymorphisms remains a critical challenge in precision medicine. EnTao-GPM, developed by Fudan University and BioMap, addresses this through three innovations: (1) Cross-species targeted pre-training on disease-relevant mammalian genomes (human, pig, mouse), leveraging evolutionary conservation to enhance interpretation of pathogenic motifs, particularly in non-coding regions; (2) Germline mutation specialization via fine-tuning on ClinVar and HGMD, improving accuracy for both SNVs and non-SNVs; (3) Interpretable clinical framework integrating DNA sequence embeddings with LLM-based statistical explanations to provide actionable insights. Validated against ClinVar, EnTao-GPM demonstrates superior accuracy in mutation classification. It revolutionizes genetic testing by enabling faster, more accurate, and accessible interpretation for clinical diagnostics (e.g., variant assessment, risk identification, personalized treatment) and research, advancing personalized medicine.

q-bio.GN↗

arXiv2025

LLMs are Introvert

The exponential growth of social media and generative AI has transformed information dissemination, fostering connectivity but also accelerating the spread of misinformation. Understanding information propagation dynamics and developing effective control strategies is essential to mitigate harmful content. Traditional models, such as SIR, provide basic insights but inadequately capture the complexities of online interactions. Advanced methods, including attention mechanisms and graph neural networks, enhance accuracy but typically overlook user psychology and behavioral dynamics. Large language models (LLMs), with their human-like reasoning, offer new potential for simulating psychological aspects of information spread. We introduce an LLM-based simulation environment capturing agents' evolving attitudes, emotions, and responses. Initial experiments, however, revealed significant gaps between LLM-generated behaviors and authentic human dynamics, especially in stance detection and psychological realism. A detailed evaluation through Social Information Processing Theory identified major discrepancies in goal-setting and feedback evaluation, stemming from the lack of emotional processing in standard LLM training. To address these issues, we propose the Social Information Processing-based Chain of Thought (SIP-CoT) mechanism enhanced by emotion-guided memory. This method improves the interpretation of social cues, personalization of goals, and evaluation of feedback. Experimental results confirm that SIP-CoT-enhanced LLM agents more effectively process social information, demonstrating behaviors, attitudes, and emotions closer to real human interactions. In summary, this research highlights critical limitations in current LLM-based propagation simulations and demonstrates how integrating SIP-CoT and emotional memory significantly enhances the social intelligence and realism of LLM agents.

cs.AI↗

arXiv2025

PLUS: Plug-and-Play Enhanced Liver Lesion Diagnosis Model on Non-Contrast CT Scans

Focal liver lesions (FLL) are common clinical findings during physical examination. Early diagnosis and intervention of liver malignancies are crucial to improving patient survival. Although the current 3D segmentation paradigm can accurately detect lesions, it faces limitations in distinguishing between malignant and benign liver lesions, primarily due to its inability to differentiate subtle variations between different lesions. Furthermore, existing methods predominantly rely on specialized imaging modalities such as multi-phase contrast-enhanced CT and magnetic resonance imaging, whereas non-contrast CT (NCCT) is more prevalent in routine abdominal imaging. To address these limitations, we propose PLUS, a plug-and-play framework that enhances FLL analysis on NCCT images for arbitrary 3D segmentation models. In extensive experiments involving 8,651 patients, PLUS demonstrated a significant improvement with existing methods, improving the lesion-level F1 score by 5.66%, the malignant patient-level F1 score by 6.26%, and the benign patient-level F1 score by 4.03%. Our results demonstrate the potential of PLUS to improve malignant FLL screening using widely available NCCT imaging substantially.

eess.IV↗

arXiv2025

Lifelong Evolution: Collaborative Learning between Large and Small Language Models for Continuous Emergent Fake News Detection

The widespread dissemination of fake news on social media has significantly impacted society, resulting in serious consequences. Conventional deep learning methodologies employing small language models (SLMs) suffer from extensive supervised training requirements and difficulties adapting to evolving news environments due to data scarcity and distribution shifts. Large language models (LLMs), despite robust zero-shot capabilities, fall short in accurately detecting fake news owing to outdated knowledge and the absence of suitable demonstrations. In this paper, we propose a novel Continuous Collaborative Emergent Fake News Detection (C$^2$EFND) framework to address these challenges. The C$^2$EFND framework strategically leverages both LLMs' generalization power and SLMs' classification expertise via a multi-round collaborative learning framework. We further introduce a lifelong knowledge editing module based on a Mixture-of-Experts architecture to incrementally update LLMs and a replay-based continue learning method to ensure SLMs retain prior knowledge without retraining entirely. Extensive experiments on Pheme and Twitter16 datasets demonstrate that C$^2$EFND significantly outperforms existed methods, effectively improving detection accuracy and adaptability in continuous emergent fake news scenarios.

cs.CL↗

arXiv2025

PFMBench: Protein Foundation Model Benchmark

This study investigates the current landscape and future directions of protein foundation model research. While recent advancements have transformed protein science and engineering, the field lacks a comprehensive benchmark for fair evaluation and in-depth understanding. Since ESM-1B, numerous protein foundation models have emerged, each with unique datasets and methodologies. However, evaluations often focus on limited tasks tailored to specific models, hindering insights into broader generalization and limitations. Specifically, researchers struggle to understand the relationships between tasks, assess how well current models perform across them, and determine the criteria in developing new foundation models. To fill this gap, we present PFMBench, a comprehensive benchmark evaluating protein foundation models across 38 tasks spanning 8 key areas of protein science. Through hundreds of experiments on 17 state-of-the-art models across 38 tasks, PFMBench reveals the inherent correlations between tasks, identifies top-performing models, and provides a streamlined evaluation protocol. Code is available at \href{https://github.com/biomap-research/PFMBench}{\textcolor{blue}{GitHub}}.

q-bio.BM↗

arXiv2025

A novel implementation of Yau-Yau filter for time-variant nonlinear problems

Nonlinear filter has long been an important problem in practical industrial applications. The Yau-Yau method is a highly versatile framework that transforms nonlinear filtering problems into initial-value problems governed by the Forward Kolmogorov Equation (FKE). Previous researches have shown that the method can be applied to highly nonlinear and high dimensional problems. However, when time-varying coefficients are involved in the system models, developing an implementation of the method with high computational speed and low data storage still presents a challenge. To address these limitations, this paper proposes a novel numerical algorithm that incorporates physics-informed neural network (PINN) and principal component analysis (PCA) to solve the FKE approximately. Equipped with this algorithm, the Yau-Yau filter can be implemented by an offline stage for the training of a solver for the approximate solution of FKE and an online stage for its execution. Results of three examples indicate that this implementation is accurate, both time-efficient and storage-efficient for online computation, and is superior than existing nonlinear filtering methods such as extended Kalman filter and particle filter. It is capable of applications to practical nonlinear time-variant filtering problems.

math.OC↗

arXiv2025

Refining Interactions: Enhancing Anisotropy in Graph Neural Networks with Language Semantics

The integration of Large Language Models (LLMs) with Graph Neural Networks (GNNs) has recently been explored to enhance the capabilities of Text Attribute Graphs (TAGs). Most existing methods feed textual descriptions of the graph structure or neighbouring nodes' text directly into LLMs. However, these approaches often cause LLMs to treat structural information simply as general contextual text, thus limiting their effectiveness in graph-related tasks. In this paper, we introduce LanSAGNN (Language Semantic Anisotropic Graph Neural Network), a framework that extends the concept of anisotropic GNNs to the natural language level. This model leverages LLMs to extract tailor-made semantic information for node pairs, effectively capturing the unique interactions within node relationships. In addition, we propose an efficient dual-layer LLMs finetuning architecture to better align LLMs' outputs with graph tasks. Experimental results demonstrate that LanSAGNN significantly enhances existing LLM-based methods without increasing complexity while also exhibiting strong robustness against interference.

cs.CL↗

arXiv2025

Resolving phonon-mediated superconducting pairing symmetries from first-principles calculation

The quest for topological superconductors triggers revived interests in resolving non-s-wave pairing channels mediated by phonons. While density functional theory and density functional perturbtaion theory have established a powerful framework to calculate electron-phonon couplings in real materials in a first-principles way, its application is largely limited to conventional s-wave superconductivity. Here, we formulate an efficient and simple-to-use algorithm for first-principles pairing channel analysis, and apply it to several representative material systems.

cond-mat.supr-con↗

arXiv2025

Collaborative Evolution: Multi-Round Learning Between Large and Small Language Models for Emergent Fake News Detection

The proliferation of fake news on social media platforms has exerted a substantial influence on society, leading to discernible impacts and deleterious consequences. Conventional deep learning methodologies employing small language models (SLMs) suffer from the necessity for extensive supervised training and the challenge of adapting to rapidly evolving circumstances. Large language models (LLMs), despite their robust zero-shot capabilities, have fallen short in effectively identifying fake news due to a lack of pertinent demonstrations and the dynamic nature of knowledge. In this paper, a novel framework Multi-Round Collaboration Detection (MRCD) is proposed to address these aforementioned limitations. The MRCD framework is capable of enjoying the merits from both LLMs and SLMs by integrating their generalization abilities and specialized functionalities, respectively. Our approach features a two-stage retrieval module that selects relevant and up-to-date demonstrations and knowledge, enhancing in-context learning for better detection of emerging news events. We further design a multi-round learning framework to ensure more reliable detection results. Our framework MRCD achieves SOTA results on two real-world datasets Pheme and Twitter16, with accuracy improvements of 7.4\% and 12.8\% compared to using only SLMs, which effectively addresses the limitations of current models and improves the detection of emergent fake news.

cs.CL↗