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Xiaopeng Ma

Publications and source records attributed to Xiaopeng Ma.

4 recordsLinked to original sources

Harmonic-Aware Transformer for Real-Time Catheter Localization in Interventional Procedures of Magnetic Particle Imaging

Magnetic particle imaging (MPI) enables real-time, radiation-free tracking of magnetic nanoparticle-coated instruments, making it highly suitable for interventional procedures. This study proposes a harmonic-aware transformer framework that directly predicts catheter tip positions from raw MPI voltage signals, eliminating the need for image reconstruction and reducing computational latency. The framework incorporates frequency-domain preprocessing to isolate the 2nd to 8th drive-field harmonics, enhancing the signal-to-noise ratio while preserving motion-relevant features. A transformer architecture with six encoder layers and eight attention heads is employed to learn spatio-temporal dependencies across the three receive axes (x, y, z) for accurate three-dimensional position estimation. The model is trained on simulated MPI signals and evaluated on real in vitro datasets under standard, bending, and heartbeat-like motion conditions. The proposed method achieves sub-millimeter localization accuracy, with a minimum L2 error of 0.103 +/- 0.092 mm and mean absolute errors (MAEs) of 0.039 +/- 0.046 mm, 0.054 +/- 0.049 mm, and 0.060 +/- 0.044 mm along the (x, y, z) axes, respectively, for the bending dataset. Across all datasets, the MAE ranges from 0.165 mm to 0.655 mm, demonstrating consistent performance. The optimized inference achieves a latency of 0.55 ms per frame and a throughput of approximately 1800 frames per second, confirming real-time capability. Compared with conventional MPI-guided approaches relying on image reconstruction, the proposed framework provides improved accuracy, reduced latency, and enhanced robustness under complex motion conditions. These results highlight the potential of harmonic-aware transformer models as efficient and scalable solutions for real-time catheter localization in interventional MPI.

physics.med-ph

Cross-Axis Weighted Harmonic Method: A Frequency-Domain Approach for Enhanced Resolution in Magnetic Particle Imaging

Magnetic Particle Imaging (MPI) is a promising imaging modality that tracks magnetic nanoparticles (MNPs) to generate real time, high-resolution images. However, achieving an optimal balance between strong signal strength and sharp image clarity remains challenging. Higher drive field frequencies improve the signal-to-noise ratio (SNR), but also risk image blurring due to nanoparticle relaxation effects. To address this, we developed an end-to-end MPI simulation framework that models MNPs behavior, magnetic field dynamics, signal acquisition, and image reconstruction across a wide frequency range (20 to 85 kHz). Central to this framework is Cross-Axis Harmonic Analysis (CAHA), a novel, frequency-domain signal processing technique that adaptively extracts high-SNR harmonics from the x, y, and z directions for improved signal reconstruction. Using a simulated 3D vascular phantom, CAHA significantly enhanced image quality, achieving sub-millimeter resolution (0.8 mm FWHM at 85 kHz), strong noise suppression (nRMSE as low as 0.01), and structural fidelity (SSIM up to 0.94 at 55 kHz). The peak SNR reached 29.7 dB at 85 kHz. The signal processed with CAHA was also tested with other reconstruction methods; when combined with total variation regularization, CAHA achieved a pSNR of 37.91 dB. Evaluation on the Open MPI dataset further demonstrated up to 20% resolution improvement, confirming CAHA's robustness on real-world data. Although minor blurring was observed at the highest frequency due to relaxation, CAHA consistently maintained image clarity. By leveraging directional harmonic content rather than the full signal, CAHA sets a new benchmark for sharper, faster, and more robust MPI imaging.

physics.med-ph

High-Resolution Magnetic Particle Imaging System Matrix Recovery Using a Vision Transformer with Residual Feature Network

This study presents a hybrid deep learning framework, the Vision Transformer with Residual Feature Network (VRF-Net), for recovering high-resolution system matrices in Magnetic Particle Imaging (MPI). MPI resolution often suffers from downsampling and coil sensitivity variations. VRF-Net addresses these challenges by combining transformer-based global attention with residual convolutional refinement, enabling recovery of both large-scale structures and fine details. To reflect realistic MPI conditions, the system matrix is degraded using a dual-stage downsampling strategy. Training employed paired-image super-resolution on the public Open MPI dataset and a simulated dataset incorporating variable coil sensitivity profiles. For system matrix recovery on the Open MPI dataset, VRF-Net achieved nRMSE = 0.403, pSNR = 39.08 dB, and SSIM = 0.835 at 2x scaling, and maintained strong performance even at challenging scale 8x (pSNR = 31.06 dB, SSIM = 0.717). For the simulated dataset, VRF-Net achieved nRMSE = 4.44, pSNR = 28.52 dB, and SSIM = 0.771 at 2x scaling, with stable performance at higher scales. On average, it reduced nRMSE by 88.2%, increased pSNR by 44.7%, and improved SSIM by 34.3% over interpolation and CNN-based methods. In image reconstruction of Open MPI phantoms, VRF-Net further reduced reconstruction error to nRMSE = 1.79 at 2x scaling, while preserving structural fidelity (pSNR = 41.58 dB, SSIM = 0.960), outperforming existing methods. These findings demonstrate that VRF-Net enables sharper, artifact-free system matrix recovery and robust image reconstruction across multiple scales, offering a promising direction for future in vivo applications.

physics.med-ph

An Adaptive Approach for Anomaly Detector Selection and Fine-Tuning in Time Series

The anomaly detection of time series is a hotspot of time series data mining. The own characteristics of different anomaly detectors determine the abnormal data that they are good at. There is no detector can be optimizing in all types of anomalies. Moreover, it still has difficulties in industrial production due to problems such as a single detector can't be optimized at different time windows of the same time series. This paper proposes an adaptive model based on time series characteristics and selecting appropriate detector and run-time parameters for anomaly detection, which is called ATSDLN(Adaptive Time Series Detector Learning Network). We take the time series as the input of the model, and learn the time series representation through FCN. In order to realize the adaptive selection of detectors and run-time parameters according to the input time series, the outputs of FCN are the inputs of two sub-networks: the detector selection network and the run-time parameters selection network. In addition, the way that the variable layer width design of the parameter selection sub-network and the introduction of transfer learning make the model be with more expandability. Through experiments, it is found that ATSDLN can select appropriate anomaly detector and run-time parameters, and have strong expandability, which can quickly transfer. We investigate the performance of ATSDLN in public data sets, our methods outperform other methods in most cases with higher effect and better adaptation. We also show experimental results on public data sets to demonstrate how model structure and transfer learning affect the effectiveness.

stat.ML