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Xiaoting Chen

Publications and source records attributed to Xiaoting Chen.

5 recordsLinked to original sources

Quaternionic Response Geometry for Proteins: Toward a Noncommutative Theory of Ordered Deformations

Protein function may depend not only on endpoint conformations but also on the ordered deformation histories through which they are reached. This distinction is relevant to allostery, conformational switching, mutation-induced rearrangements, and epistatic effects, where different perturbation sequences may produce similar visible structures while retaining distinct internal transport histories. Current state-centered or endpoint-centered representations do not always preserve this order-sensitive information. The practical motivation is therefore to provide a foundation for future descriptors of protein deformation trajectories that can distinguish ordered histories even when endpoint conformations are similar. We propose a deformation-first geometric framework based on quaternionic frame transport along the protein backbone. Local backbone frames are lifted to quaternionic variables, with infinitesimal rotation encoded by \(\Omega(\ell)=2\,q(\ell)^{-1}\partial_\ell q(\ell).\) Ordered concatenation of admissible deformation paths generates a noncommutative transport algebra, recording that deformation A followed by B need not be equivalent to B followed by A. From this ordered transport layer, we construct a spectral-response layer comprising a global Dirac-type operator, local spectral germs, a renormalized spectral density, and a mixed response form. A minimal realization on an idealized \(\alpha\)-helix shows how localized pitch and bending perturbations can yield similar endpoint descriptors while producing a nonzero endpoint-derived ordered-transport discrepancy. At the formal level, the framework separates an order-sensitive transport-memory sector, lost under a commutative shadow, from a spectral-response sector that remains visible.

q-bio.BM

Discoverability matters: Open access models and the translation of science into patents

Scientific research is a key input into technological innovation, yet not all scientific knowledge is equally mobilized in patents. This paper examines how different scientific publishing models shape both the selection of scientific publications cited in patents and their cognitive alignment with patented technologies. Using large-scale data on non-patent references linking patents to scientific publications, combined with metadata from OpenAlex, we compare the Open Access (OA) structure of patent-cited science to that of the scientific literature. We then assess cognitive alignment using semantic similarity between patent abstracts and the abstracts of cited publications, distinguishing between citations appearing in the front section of patents and those embedded in the body of patent texts. We find that patent citations disproportionately draw on publications disseminated through highly visible and institutionally established publishing channels, particularly hybrid and bronze OA models, indicating strong selection effects. However, this dominance in citation counts does not translate into stronger cognitive alignment with patented technologies. On the contrary, publications in fully OA journals (gold and diamond OA) exhibit equal or higher semantic proximity, especially when cited in the body of patents. These results suggest that the contribution of OA to innovation depends less on access alone than on how different publishing models are embedded in information infrastructures that shape the visibility, discoverability, and use of scientific knowledge.

cs.DL

MUSE: Flexible Voiceprint Receptive Fields and Multi-Path Fusion Enhanced Taylor Transformer for U-Net-based Speech Enhancement

Achieving a balance between lightweight design and high performance remains a challenging task for speech enhancement. In this paper, we introduce Multi-path Enhanced Taylor (MET) Transformer based U-net for Speech Enhancement (MUSE), a lightweight speech enhancement network built upon the Unet architecture. Our approach incorporates a novel Multi-path Enhanced Taylor (MET) Transformer block, which integrates Deformable Embedding (DE) to enable flexible receptive fields for voiceprints. The MET Transformer is uniquely designed to fuse Channel and Spatial Attention (CSA) branches, facilitating channel information exchange and addressing spatial attention deficits within the Taylor-Transformer framework. Through extensive experiments conducted on the VoiceBank+DEMAND dataset, we demonstrate that MUSE achieves competitive performance while significantly reducing both training and deployment costs, boasting a mere 0.51M parameters.

cs.SD

Global and Local Mixture Consistency Cumulative Learning for Long-tailed Visual Recognitions

In this paper, our goal is to design a simple learning paradigm for long-tail visual recognition, which not only improves the robustness of the feature extractor but also alleviates the bias of the classifier towards head classes while reducing the training skills and overhead. We propose an efficient one-stage training strategy for long-tailed visual recognition called Global and Local Mixture Consistency cumulative learning (GLMC). Our core ideas are twofold: (1) a global and local mixture consistency loss improves the robustness of the feature extractor. Specifically, we generate two augmented batches by the global MixUp and local CutMix from the same batch data, respectively, and then use cosine similarity to minimize the difference. (2) A cumulative head tail soft label reweighted loss mitigates the head class bias problem. We use empirical class frequencies to reweight the mixed label of the head-tail class for long-tailed data and then balance the conventional loss and the rebalanced loss with a coefficient accumulated by epochs. Our approach achieves state-of-the-art accuracy on CIFAR10-LT, CIFAR100-LT, and ImageNet-LT datasets. Additional experiments on balanced ImageNet and CIFAR demonstrate that GLMC can significantly improve the generalization of backbones. Code is made publicly available at https://github.com/ynu-yangpeng/GLMC.

cs.CV

Operator transpose within normal ordering and its applications for quantifying entanglement

Partial transpose is an important operation for quantifying the entanglement, here we study the (partial) transpose of any single (two-mode) operators. Using the Fock-basis expansion, it is found that the transposed operator of an arbitrary operator can be obtained by replacement of a^{†}(a) by a(a^{†}) instead of c-number within normal ordering form. The transpose of displacement operator and Wigner operator are studied, from which the relation of Wigner function, characteristics function and average values such as covariance matrix are constructed between density operator and transposed density operator. These observations can be further extended to multi-mode cases. As applications, the partial transpose of two-mode squeezed operator and the entanglement of two-mode squeezed vacuum through a laser channel are considered.

quant-ph