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Xiaotong Shen

Publications and source records attributed to Xiaotong Shen.

32 records · Page 2Linked to original sources

Discovery and inference of a causal network with hidden confounding

This article proposes a novel causal discovery and inference method called GrIVET for a Gaussian directed acyclic graph with unmeasured confounders. GrIVET consists of an order-based causal discovery method and a likelihood-based inferential procedure. For causal discovery, we generalize the existing peeling algorithm to estimate the ancestral relations and candidate instruments in the presence of hidden confounders. Based on this, we propose a new procedure for instrumental variable estimation of each direct effect by separating it from any mediation effects. For inference, we develop a new likelihood ratio test of multiple causal effects that is able to account for the unmeasured confounders. Theoretically, we prove that the proposed method has desirable guarantees, including robustness to invalid instruments and uncertain interventions, estimation consistency, low-order polynomial time complexity, and validity of asymptotic inference. Numerically, GrIVET performs well and compares favorably against state-of-the-art competitors. Furthermore, we demonstrate the utility and effectiveness of the proposed method through an application inferring regulatory pathways from Alzheimer's disease gene expression data.

stat.ME↗

A Spectral Approach for the Dynamic Bradley-Terry Model

The dynamic ranking, due to its increasing importance in many applications, is becoming crucial, especially with the collection of voluminous time-dependent data. One such application is sports statistics, where dynamic ranking aids in forecasting the performance of competitive teams, drawing on historical and current data. Despite its usefulness, predicting and inferring rankings pose challenges in environments necessitating time-dependent modeling. This paper introduces a spectral ranker called Kernel Rank Centrality, designed to rank items based on pairwise comparisons over time. The ranker operates via kernel smoothing in the Bradley-Terry model, utilizing a Markov chain model. Unlike the maximum likelihood approach, the spectral ranker is nonparametric, demands fewer model assumptions and computations, and allows for real-time ranking. We establish the asymptotic distribution of the ranker by applying an innovative group inverse technique, resulting in a uniform and precise entrywise expansion. This result allows us to devise a new inferential method for predictive inference, previously unavailable in existing approaches. Our numerical examples showcase the ranker's utility in predictive accuracy and constructing an uncertainty measure for prediction, leveraging data from the National Basketball Association (NBA). The results underscore our method's potential compared to the gold standard in sports, the Arpad Elo rating system.

stat.ME↗

Inference for a Large Directed Acyclic Graph with Unspecified Interventions

Statistical inference of directed relations given some unspecified interventions (i.e., the intervention targets are unknown) is challenging. In this article, we test hypothesized directed relations with unspecified interventions. First, we derive conditions to yield an identifiable model. Unlike classical inference, testing directed relations requires identifying the ancestors and relevant interventions of hypothesis-specific primary variables. To this end, we propose a peeling algorithm based on nodewise regressions to establish a topological order of primary variables. Moreover, we prove that the peeling algorithm yields a consistent estimator in low-order polynomial time. Second, we propose a likelihood ratio test integrated with a data perturbation scheme to account for the uncertainty of identifying ancestors and interventions. Also, we show that the distribution of a data perturbation test statistic converges to the target distribution. Numerical examples demonstrate the utility and effectiveness of the proposed methods, including an application to infer gene regulatory networks. The R implementation is available at https://github.com/chunlinli/intdag.

stat.ME↗

Data-Adaptive Discriminative Feature Localization with Statistically Guaranteed Interpretation

In explainable artificial intelligence, discriminative feature localization is critical to reveal a blackbox model's decision-making process from raw data to prediction. In this article, we use two real datasets, the MNIST handwritten digits and MIT-BIH Electrocardiogram (ECG) signals, to motivate key characteristics of discriminative features, namely adaptiveness, predictive importance and effectiveness. Then, we develop a localization framework based on adversarial attacks to effectively localize discriminative features. In contrast to existing heuristic methods, we also provide a statistically guaranteed interpretability of the localized features by measuring a generalized partial $R^2$. We apply the proposed method to the MNIST dataset and the MIT-BIH dataset with a convolutional auto-encoder. In the first, the compact image regions localized by the proposed method are visually appealing. Similarly, in the second, the identified ECG features are biologically plausible and consistent with cardiac electrophysiological principles while locating subtle anomalies in a QRS complex that may not be discernible by the naked eye. Overall, the proposed method compares favorably with state-of-the-art competitors. Accompanying this paper is a Python library dnn-locate (https://dnn-locate.readthedocs.io/en/latest/) that implements the proposed approach.

stat.ML↗

Significance tests of feature relevance for a black-box learner

An exciting recent development is the uptake of deep neural networks in many scientific fields, where the main objective is outcome prediction with the black-box nature. Significance testing is promising to address the black-box issue and explore novel scientific insights and interpretation of the decision-making process based on a deep learning model. However, testing for a neural network poses a challenge because of its black-box nature and unknown limiting distributions of parameter estimates while existing methods require strong assumptions or excessive computation. In this article, we derive one-split and two-split tests relaxing the assumptions and computational complexity of existing black-box tests and extending to examine the significance of a collection of features of interest in a dataset of possibly a complex type such as an image. The one-split test estimates and evaluates a black-box model based on estimation and inference subsets through sample splitting and data perturbation. The two-split test further splits the inference subset into two but require no perturbation. Also, we develop their combined versions by aggregating the p-values based on repeated sample splitting. By deflating the bias-sd-ratio, we establish asymptotic null distributions of the test statistics and the consistency in terms of Type II error. Numerically, we demonstrate the utility of the proposed tests on seven simulated examples and six real datasets. Accompanying this paper is our Python library dnn-inference (https://dnn-inference.readthedocs.io/en/latest/) that implements the proposed tests.

stat.ML↗

Distribution-Invariant Differential Privacy

Differential privacy is becoming one gold standard for protecting the privacy of publicly shared data. It has been widely used in social science, data science, public health, information technology, and the U.S. decennial census. Nevertheless, to guarantee differential privacy, existing methods may unavoidably alter the conclusion of the original data analysis, as privatization often changes the sample distribution. This phenomenon is known as the trade-off between privacy protection and statistical accuracy. In this work, we mitigate this trade-off by developing a distribution-invariant privatization (DIP) method to reconcile both high statistical accuracy and strict differential privacy. As a result, any downstream statistical or machine learning task yields essentially the same conclusion as if one used the original data. Numerically, under the same strictness of privacy protection, DIP achieves superior statistical accuracy in a wide range of simulation studies and real-world benchmarks.

cs.CR↗

Two-level monotonic multistage recommender systems

A recommender system learns to predict the user-specific preference or intention over many items simultaneously for all users, making personalized recommendations based on a relatively small number of observations. One central issue is how to leverage three-way interactions, referred to as user-item-stage dependencies on a monotonic chain of events, to enhance the prediction accuracy. A monotonic chain of events occurs, for instance, in an article sharing dataset, where a ``follow'' action implies a ``like'' action, which in turn implies a ``view'' action. In this article, we develop a multistage recommender system utilizing a two-level monotonic property characterizing a monotonic chain of events for personalized prediction. Particularly, we derive a large-margin classifier based on a nonnegative additive latent factor model in the presence of a high percentage of missing observations, particularly between stages, reducing the number of model parameters for personalized prediction while guaranteeing prediction consistency. On this ground, we derive a regularized cost function to learn user-specific behaviors at different stages, linking decision functions to numerical and categorical covariates to model user-item-stage interactions. Computationally, we derive an algorithm based on blockwise coordinate descent. Theoretically, we show that the two-level monotonic property enhances the accuracy of learning as compared to a standard method treating each stage individually and an ordinal method utilizing only one-level monotonicity. Finally, the proposed method compares favorably with existing methods in simulations and an article sharing dataset.

cs.IR↗

Multilayer tensor factorization with applications to recommender systems

Recommender systems have been widely adopted by electronic commerce and entertainment industries for individualized prediction and recommendation, which benefit consumers and improve business intelligence. In this article, we propose an innovative method, namely the recommendation engine of multilayers (REM), for tensor recommender systems. The proposed method utilizes the structure of a tensor response to integrate information from multiple modes, and creates an additional layer of nested latent factors to accommodate between-subjects dependency. One major advantage is that the proposed method is able to address the "cold-start" issue in the absence of information from new customers, new products or new contexts. Specifically, it provides more effective recommendations through sub-group information. To achieve scalable computation, we develop a new algorithm for the proposed method, which incorporates a maximum block improvement strategy into the cyclic blockwise-coordinate-descent algorithm. In theory, we investigate both algorithmic properties for global and local convergence, along with the asymptotic consistency of estimated parameters. Finally, the proposed method is applied in simulations and IRI marketing data with 116 million observations of product sales. Numerical studies demonstrate that the proposed method outperforms existing competitors in the literature.

stat.ML↗

A General Framework for Multi-vehicle Cooperative Localization Using Pose Graph

When a vehicle observes another one, the two vehicles' poses are correlated by this spatial relative observation, which can be used in cooperative localization for further increasing localization accuracy and precision. To use spatial relative observations, we propose to add them into a pose graph for optimal pose estimation. Before adding them, we need to know the identities of the observed vehicles. The vehicle identification is formulated as a linear assignment problem, which can be solved efficiently. By using pose graph techniques and the start-of-the-art factor composition/decomposition method, our cooperative localization algorithm is robust against communication delay, packet loss, and out-of-sequence packet reception. We demonstrate the usability of our framework and effectiveness of our algorithm through both simulations and real-world experiments using three vehicles on the road.

cs.RO↗

Fused Multiple Graphical Lasso

In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain networks of Alzheimer's disease using neuroimaging data. Specifically, we may wish to estimate a brain network for the normal controls (NC), a brain network for the patients with mild cognitive impairment (MCI), and a brain network for Alzheimer's patients (AD). We expect the two brain networks for NC and MCI to share common structures but not to be identical to each other; similarly for the two brain networks for MCI and AD. The proposed formulation can be solved using a second-order method. Our key technical contribution is to establish the necessary and sufficient condition for the graphs to be decomposable. Based on this key property, a simple screening rule is presented, which decomposes the large graphs into small subgraphs and allows an efficient estimation of multiple independent (small) subgraphs, dramatically reducing the computational cost. We perform experiments on both synthetic and real data; our results demonstrate the effectiveness and efficiency of the proposed approach.

cs.LG↗

Efficient Sparse Group Feature Selection via Nonconvex Optimization

Sparse feature selection has been demonstrated to be effective in handling high-dimensional data. While promising, most of the existing works use convex methods, which may be suboptimal in terms of the accuracy of feature selection and parameter estimation. In this paper, we expand a nonconvex paradigm to sparse group feature selection, which is motivated by applications that require identifying the underlying group structure and performing feature selection simultaneously. The main contributions of this article are twofold: (1) statistically, we introduce a nonconvex sparse group feature selection model which can reconstruct the oracle estimator. Therefore, consistent feature selection and parameter estimation can be achieved; (2) computationally, we propose an efficient algorithm that is applicable to large-scale problems. Numerical results suggest that the proposed nonconvex method compares favorably against its competitors on synthetic data and real-world applications, thus achieving desired goal of delivering high performance.

cs.LG↗

Penalized model-based clustering with cluster-specific diagonal covariance matrices and grouped variables

Clustering analysis is one of the most widely used statistical tools in many emerging areas such as microarray data analysis. For microarray and other high-dimensional data, the presence of many noise variables may mask underlying clustering structures. Hence removing noise variables via variable selection is necessary. For simultaneous variable selection and parameter estimation, existing penalized likelihood approaches in model-based clustering analysis all assume a common diagonal covariance matrix across clusters, which however may not hold in practice. To analyze high-dimensional data, particularly those with relatively low sample sizes, this article introduces a novel approach that shrinks the variances together with means, in a more general situation with cluster-specific (diagonal) covariance matrices. Furthermore, selection of grouped variables via inclusion or exclusion of a group of variables altogether is permitted by a specific form of penalty, which facilitates incorporating subject-matter knowledge, such as gene functions in clustering microarray samples for disease subtype discovery. For implementation, EM algorithms are derived for parameter estimation, in which the M-steps clearly demonstrate the effects of shrinkage and thresholding. Numerical examples, including an application to acute leukemia subtype discovery with microarray gene expression data, are provided to demonstrate the utility and advantage of the proposed method.

stat.ML↗

Generalization error for multi-class margin classification

In this article, we study rates of convergence of the generalization error of multi-class margin classifiers. In particular, we develop an upper bound theory quantifying the generalization error of various large margin classifiers. The theory permits a treatment of general margin losses, convex or nonconvex, in presence or absence of a dominating class. Three main results are established. First, for any fixed margin loss, there may be a trade-off between the ideal and actual generalization performances with respect to the choice of the class of candidate decision functions, which is governed by the trade-off between the approximation and estimation errors. In fact, different margin losses lead to different ideal or actual performances in specific cases. Second, we demonstrate, in a problem of linear learning, that the convergence rate can be arbitrarily fast in the sample size $n$ depending on the joint distribution of the input/output pair. This goes beyond the anticipated rate $O(n^{-1})$. Third, we establish rates of convergence of several margin classifiers in feature selection with the number of candidate variables $p$ allowed to greatly exceed the sample size $n$ but no faster than $\exp(n)$.

math.ST↗