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Xiaoxu Lu

Publications and source records attributed to Xiaoxu Lu.

3 recordsLinked to original sources

Single-shot structured illumination microscopy

Structured illumination microscopy (SIM) can double the resolution beyond the light diffraction limit, but it comes at the cost of multiple camera exposures and the heavy computation burden of multiple Fourier transforms. In this paper, we report a novel technique termed single-shot SIM, to overcome these limitations. A multi-task joint deep-learning strategy is proposed. Generative adversative networks (GAN) are employed to generate five structured illumination images based on the single-shot structured illumination image. U-Net is employed to reconstruct the super-resolution image from these six generated images without time-consuming Fourier transform. By imaging a self-assembling DNB array, we experimentally verified that this technique could perform single-shot super-resolution reconstruction comparing favorably with conventional SIM. This single-shot SIM technique may ultimately overcome the limitations of multiple exposures and Fourier transforms and is potentially applied for high-throughput gene sequencing.

eess.IV

Deep Phase Shifter for Quantitative Phase Imaging

A single intensity-only holographic interferogram can records the full amplitude and phase information of optical field. However, current digital holography technologies cannot recover the lossless phase information from a single interferogram. In this paper, we provide an entirely new approach for the full-field quantitative phase imaging technology. We demonstrate that deep learning can be used to replace the entitative phase shifter, and quantitative phase imaging can obtain quantitative phase from a single interferogram in in-line holography. A deep-phase-shift network (DPS-net) is reported, which can be trained with simulation training data. The trained DPS-net can be used to generate multiple interferograms with arbitrary phase shift from a single interferogram as an artificial intelligence phase shifter. The ability and the accuracy of generating arbitrary phase shifts are verified, and the performance of the proposed method is also verified by the experimental interferogram. The results demonstrate that the proposed method can provide a full digital phase shifter with high-accuracy for the technology of dynamic quantitative phase measurement.

eess.IV

Polarization manipulation holographic lithography by single refracting prism

We propose a simple but effective strategy for polarization manipulation holographic lithography by single refractive prism. By tuning the polarization of single laser beam, we simply obtain a pill shape interference pattern where multiple modulated beams are needed in conventional holography lithography. Fabrication of large area pill shape two-dimensional polymer photonic crystals template using one beam and one shoot holography lithography is shown as an example. This integrated fabrication technique, for example, can release the crucial stability restrictions imposed on the multiple beams holography lithography.

physics.optics