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Xiaoyan Wu

Publications and source records attributed to Xiaoyan Wu.

13 recordsLinked to original sources

CorePath: A Breast-Specialized Pathology Foundation Model for Core Needle Biopsy Diagnosis and Risk-Controlled Report Generation

Breast core needle biopsy (CNB) is central to breast cancer diagnosis yet remains challenging because limited tissue sampling, lesion heterogeneity, and subtle morphologic overlap can obscure subtype distinctions. We developed CorePath, a breast-specialized multimodal pathology foundation model fine-tuned from PRISM using 7901 paired CNB whole-slide images and diagnostic reports from two centers. Evaluated across six CNB cohorts and two public breast pathology benchmarks without task-specific retraining, CorePath consistently outperformed PRISM across cancer detection, invasion assessment, and histological subtyping. It achieved weighted area under the receiver operating characteristic curves (AUCs) of 0.9526-0.9735 for five-class CNB histological subtyping across private centers. On public benchmarks, CorePath outperformed leading pathology foundation models, achieving the highest weighted AUCs of 0.7780 for BCNB invasive carcinoma subtyping, 0.8178 for BRACS lesion stratification, and 0.8252 for BRACS fine-grained classification. In report generation, CorePath reduced the overall non-breast hallucinations from 30.1% to 2.8%, demonstrating improved domain fidelity after breast-specific adaptation. CorePath-CRG further combined conformal filtering of subtype and binary cancer status predictions with Learn-Then-Test-based threshold calibration to support selective narrative release, diagnostic fallback, and deferral. CorePath-CRG achieved zero non-breast hallucinations among released outputs and showed the strongest overall performance in pathologist-validated LLM-based Evaluation Scores and quantitative report-generation metrics across most centers. These results demonstrate that domain-specialized foundation models with statistical risk control offer a promising approach for accurate breast CNB diagnosis and reliable report generation.

cs.CV

Human-like moral judgments conceal divergent motive attributions in large language models

Large language models (LLMs) are used to simulate human participants in psychological research. We asked whether LLMs that reproduce human evaluations of a whistleblower's moral character also reproduce the motive attributions that accompany them. Five LLMs and two human samples (N = 125 and N = 742) evaluated a physician who either remained silent about fraudulent billing or reported it to a hospital, regulator, or newspaper. Models reproduced the human ranking of the physician's moral character but portrayed whistleblowers as more helpful, less self-interested, and less hostile. In four of five models, competitive motives were less strongly associated with moral-character judgments. Model ratings changed little when prompts reproduced the narratives and demographic profiles of both human samples, although this comparison cannot isolate a perspective effect. Thus, agreement in average ratings can conceal differences in attributed motives, relationships among judgments, and sensitivity to context. Validating LLMs as simulated participants therefore requires testing psychologically informative response patterns, not average agreement alone.

cs.AI

Beyond Monologue: Interactive Talking-Listening Avatar Generation with Conversational Audio Context-Aware Kernels

Audio-driven human video generation has achieved remarkable success in monologue scenarios, largely driven by advancements in powerful video generation foundation models. Moving beyond monologues, authentic human communication is inherently a full-duplex interactive process, requiring virtual agents not only to articulate their own speech but also to react naturally to incoming conversational audio. Most existing methods simply extend conventional audio-driven paradigms to listening scenarios. However, relying on strict frame-to-frame alignment renders the model's response to long-range conversational dynamics rigid, whereas directly introducing global attention catastrophically degrades lip synchronization. Recognizing the unique temporal Scale Discrepancy between talking and listening behaviors, we introduce a multi-head Gaussian kernel to explicitly inject this physical intuition into the model as a progressive temporal inductive bias. Building upon this, we construct a full-duplex interactive virtual agent capable of simultaneously processing dual-stream audio inputs for both talking and listening. Furthermore, we introduce a rigorously cleaned Talking-Listening dataset VoxHear featuring perfectly decoupled speech and background audio tracks. Extensive experiments demonstrate that our approach successfully fuses strong temporal alignment with deep contextual semantics, setting a new state-of-the-art for generating highly natural and responsive full-duplex interactive digital humans. The project page is available at https://warmcongee.github.io/beyond-monologue/ .

cs.AI

EARTalking: End-to-end GPT-style Autoregressive Talking Head Synthesis with Frame-wise Control

Audio-driven talking head generation aims to create vivid and realistic videos from a static portrait and speech. Existing AR-based methods rely on intermediate facial representations, which limit their expressiveness and realism. Meanwhile, diffusion-based methods generate clip-by-clip, lacking fine-grained control and causing inherent latency due to overall denoising across the window. To address these limitations, we propose EARTalking, a novel end-to-end, GPT-style autoregressive model for interactive audio-driven talking head generation. Our method introduces a novel frame-by-frame, in-context, audio-driven streaming generation paradigm. For inherently supporting variable-length video generation with identity consistency, we propose the Sink Frame Window Attention (SFA) mechanism. Furthermore, to avoid the complex, separate networks that prior works required for diverse control signals, we propose a streaming Frame Condition In-Context (FCIC) scheme. This scheme efficiently injects diverse control signals in a streaming, in-context manner, enabling interactive control at every frame and at arbitrary moments. Experiments demonstrate that EARTalking outperforms existing autoregressive methods and achieves performance comparable to diffusion-based methods. Our work demonstrates the feasibility of in-context streaming autoregressive control, unlocking a scalable direction for flexible, efficient generation. The code will be released for reproducibility.

cs.CV

REST: Diffusion-based Real-time End-to-end Streaming Talking Head Generation via ID-Context Caching and Asynchronous Streaming Distillation

Diffusion models have significantly advanced the field of talking head generation (THG). However, slow inference speeds and prevalent non-autoregressive paradigms severely constrain the application of diffusion-based THG models. In this study, we propose REST, a pioneering diffusion-based, real-time, end-to-end streaming audio-driven talking head generation framework. To support real-time end-to-end generation, a compact video latent space is first learned through a spatiotemporal variational autoencoder with a high compression ratio. Additionally, to enable semi-autoregressive streaming within the compact video latent space, we introduce an ID-Context Cache mechanism, which integrates ID-Sink and Context-Cache principles into key-value caching for maintaining identity consistency and temporal coherence during long-term streaming generation. Furthermore, an Asynchronous Streaming Distillation (ASD) strategy is proposed to mitigate error accumulation and enhance temporal consistency in streaming generation, leveraging a non-streaming teacher with an asynchronous noise schedule to supervise the streaming student. REST bridges the gap between autoregressive and diffusion-based approaches, achieving a breakthrough in efficiency for applications requiring real-time THG. Experimental results demonstrate that REST outperforms state-of-the-art methods in both generation speed and overall performance.

cs.CV

READ: Real-time and Efficient Asynchronous Diffusion for Audio-driven Talking Head Generation

The introduction of diffusion models has brought significant advances to the field of audio-driven talking head generation. However, the extremely slow inference speed severely limits the practical implementation of diffusion-based talking head generation models. In this study, we propose READ, a real-time diffusion-transformer-based talking head generation framework. Our approach first learns a spatiotemporal highly compressed video latent space via a temporal VAE, significantly reducing the token count to accelerate generation. To achieve better audio-visual alignment within this compressed latent space, a pre-trained Speech Autoencoder (SpeechAE) is proposed to generate temporally compressed speech latent codes corresponding to the video latent space. These latent representations are then modeled by a carefully designed Audio-to-Video Diffusion Transformer (A2V-DiT) backbone for efficient talking head synthesis. Furthermore, to ensure temporal consistency and accelerated inference in extended generation, we propose a novel asynchronous noise scheduler (ANS) for both the training and inference processes of our framework. The ANS leverages asynchronous add-noise and asynchronous motion-guided generation in the latent space, ensuring consistency in generated video clips. Experimental results demonstrate that READ outperforms state-of-the-art methods by generating competitive talking head videos with significantly reduced runtime, achieving an optimal balance between quality and speed while maintaining robust metric stability in long-time generation.

cs.GR

Pure Vision Language Action (VLA) Models: A Comprehensive Survey

The emergence of Vision Language Action (VLA) models marks a paradigm shift from traditional policy-based control to generalized robotics, reframing Vision Language Models (VLMs) from passive sequence generators into active agents for manipulation and decision-making in complex, dynamic environments. This survey delves into advanced VLA methods, aiming to provide a clear taxonomy and a systematic, comprehensive review of existing research. It presents a comprehensive analysis of VLA applications across different scenarios and classifies VLA approaches into several paradigms: autoregression-based, diffusion-based, reinforcement-based, hybrid, and specialized methods; while examining their motivations, core strategies, and implementations in detail. In addition, foundational datasets, benchmarks, and simulation platforms are introduced. Building on the current VLA landscape, the review further proposes perspectives on key challenges and future directions to advance research in VLA models and generalizable robotics. By synthesizing insights from over three hundred recent studies, this survey maps the contours of this rapidly evolving field and highlights the opportunities and challenges that will shape the development of scalable, general-purpose VLA methods.

cs.RO

EmotiveTalk: Expressive Talking Head Generation through Audio Information Decoupling and Emotional Video Diffusion

Diffusion models have revolutionized the field of talking head generation, yet still face challenges in expressiveness, controllability, and stability in long-time generation. In this research, we propose an EmotiveTalk framework to address these issues. Firstly, to realize better control over the generation of lip movement and facial expression, a Vision-guided Audio Information Decoupling (V-AID) approach is designed to generate audio-based decoupled representations aligned with lip movements and expression. Specifically, to achieve alignment between audio and facial expression representation spaces, we present a Diffusion-based Co-speech Temporal Expansion (Di-CTE) module within V-AID to generate expression-related representations under multi-source emotion condition constraints. Then we propose a well-designed Emotional Talking Head Diffusion (ETHD) backbone to efficiently generate highly expressive talking head videos, which contains an Expression Decoupling Injection (EDI) module to automatically decouple the expressions from reference portraits while integrating the target expression information, achieving more expressive generation performance. Experimental results show that EmotiveTalk can generate expressive talking head videos, ensuring the promised controllability of emotions and stability during long-time generation, yielding state-of-the-art performance compared to existing methods.

cs.CV

WAL-Net: Weakly supervised auxiliary task learning network for carotid plaques classification

The classification of carotid artery ultrasound images is a crucial means for diagnosing carotid plaques, holding significant clinical relevance for predicting the risk of stroke. Recent research suggests that utilizing plaque segmentation as an auxiliary task for classification can enhance performance by leveraging the correlation between segmentation and classification tasks. However, this approach relies on obtaining a substantial amount of challenging-to-acquire segmentation annotations. This paper proposes a novel weakly supervised auxiliary task learning network model (WAL-Net) to explore the interdependence between carotid plaque classification and segmentation tasks. The plaque classification task is primary task, while the plaque segmentation task serves as an auxiliary task, providing valuable information to enhance the performance of the primary task. Weakly supervised learning is adopted in the auxiliary task to completely break away from the dependence on segmentation annotations. Experiments and evaluations are conducted on a dataset comprising 1270 carotid plaque ultrasound images from Wuhan University Zhongnan Hospital. Results indicate that the proposed method achieved an approximately 1.3% improvement in carotid plaque classification accuracy compared to the baseline network. Specifically, the accuracy of mixed-echoic plaques classification increased by approximately 3.3%, demonstrating the effectiveness of our approach.

eess.IV

Molecular Dynamics Study of Plasmon-Mediated Chemical Transformations

Heterogeneous catalysis of adsorbates on metallic surfaces mediated by plasmon has potential high photoelectric conversion efficiency and controllable reaction selectivity. Theoretical modeling of dynamical reaction processes provides in-depth analyses complementing experimental investigations. Especially for plasmon-mediated chemical transformations, light absorption, photoelectric conversion, electron-electron scattering, and electron-phonon coupling occur simultaneously at different timescales, rendering it very challenging to delineate the complex interplay of different factors. In this work, a trajectory surface hopping non-adiabatic molecular dynamics method is used to investigate the dynamics of plasmon excitation in an Au$_{20}$-CO system, including hot carrier generation, plasmon energy relaxation, and CO activation induced by electron-vibration coupling. The electronic properties indicate that when Au$_{20}$-CO is excited, a partial charge transfer takes place from Au$_{20}$ to CO. On the other hand, the dynamical simulations show that hot carriers generated after plasmon excitation transfer back and forth between Au$_{20}$ and CO. Meanwhile, the C-O stretching mode is activated due to the non-adiabatic couplings. The efficiency of plasmon-mediated transformation ($\sim$40\%) is obtained based on the ensemble average of these quantities. Our simulations provide important dynamical and atomistic insights into plasmon-mediated chemical transformation from the perspective of non-adiabatic simulations.

physics.chem-ph

Type of Non-reciprocity in Fiber Sagnac Interferometer Induced by Geometric Phases

The non-reciprocity of Sagnac interferometer provides ultra-high sensitivity for parameter estimation and offers a wide range of applications, especially for optical fiber sensing. In this work, we study a new type of non-reciprocity existed in optical fiber Sagnac interferometer where the polarization dependent loss is taken into consideration. In particular, this non-reciprocity is irrelevant to the physical effects that being considered in previous studies, which originates from the geometric phases induced by continuous-weak-measurement. In consequence, it has a unique phenomenon of sudden phase transition, which may open a new way for the future design of high precision optical fiber sensors.

physics.optics

DFGC 2021: A DeepFake Game Competition

This paper presents a summary of the DFGC 2021 competition. DeepFake technology is developing fast, and realistic face-swaps are increasingly deceiving and hard to detect. At the same time, DeepFake detection methods are also improving. There is a two-party game between DeepFake creators and detectors. This competition provides a common platform for benchmarking the adversarial game between current state-of-the-art DeepFake creation and detection methods. In this paper, we present the organization, results and top solutions of this competition and also share our insights obtained during this event. We also release the DFGC-21 testing dataset collected from our participants to further benefit the research community.

cs.CV

Photoluminescence of InGaAs/GaAsBi/InGaAs type-II quantum well grown by gas source molecular beam epitaxy

InGaAs/GaAsBi/InGaAs quantum wells (QWs) were grown on GaAs substrates by gas source molecular beam epitaxy for realizing the type II band-edge line-up. Both type I and type II transitions were observed in the Bi containing W QWs and the photoluminescence intensity was enhanced in the sample with a high Bi content, which is mainly due to the improvement of carrier confinement. Blue-shift of type II transitions at high excitation power density was observed and ascribed to the band-bending effect. The calculated transition energies based on 8 band k.p model fit well with the experiment results. The experimental and theoretical results show that the type-II QW design is a new promising candidate for realizing long wavelength GaAs-based light emitting devices near 1.3 um.

cond-mat.mtrl-sci