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Xin Yang

Publications and source records attributed to Xin Yang.

At least 253 records · Page 14Linked to original sources
arXiv2023

FFPN: Fourier Feature Pyramid Network for Ultrasound Image Segmentation

Ultrasound (US) image segmentation is an active research area that requires real-time and highly accurate analysis in many scenarios. The detect-to-segment (DTS) frameworks have been recently proposed to balance accuracy and efficiency. However, existing approaches may suffer from inadequate contour encoding or fail to effectively leverage the encoded results. In this paper, we introduce a novel Fourier-anchor-based DTS framework called Fourier Feature Pyramid Network (FFPN) to address the aforementioned issues. The contributions of this paper are two fold. First, the FFPN utilizes Fourier Descriptors to adequately encode contours. Specifically, it maps Fourier series with similar amplitudes and frequencies into the same layer of the feature map, thereby effectively utilizing the encoded Fourier information. Second, we propose a Contour Sampling Refinement (CSR) module based on the contour proposals and refined features produced by the FFPN. This module extracts rich features around the predicted contours to further capture detailed information and refine the contours. Extensive experimental results on three large and challenging datasets demonstrate that our method outperforms other DTS methods in terms of accuracy and efficiency. Furthermore, our framework can generalize well to other detection or segmentation tasks.

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arXiv2023

OnUVS: Online Feature Decoupling Framework for High-Fidelity Ultrasound Video Synthesis

Ultrasound (US) imaging is indispensable in clinical practice. To diagnose certain diseases, sonographers must observe corresponding dynamic anatomic structures to gather comprehensive information. However, the limited availability of specific US video cases causes teaching difficulties in identifying corresponding diseases, which potentially impacts the detection rate of such cases. The synthesis of US videos may represent a promising solution to this issue. Nevertheless, it is challenging to accurately animate the intricate motion of dynamic anatomic structures while preserving image fidelity. To address this, we present a novel online feature-decoupling framework called OnUVS for high-fidelity US video synthesis. Our highlights can be summarized by four aspects. First, we introduced anatomic information into keypoint learning through a weakly-supervised training strategy, resulting in improved preservation of anatomical integrity and motion while minimizing the labeling burden. Second, to better preserve the integrity and textural information of US images, we implemented a dual-decoder that decouples the content and textural features in the generator. Third, we adopted a multiple-feature discriminator to extract a comprehensive range of visual cues, thereby enhancing the sharpness and fine details of the generated videos. Fourth, we constrained the motion trajectories of keypoints during online learning to enhance the fluidity of generated videos. Our validation and user studies on in-house echocardiographic and pelvic floor US videos showed that OnUVS synthesizes US videos with high fidelity.

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arXiv2023

Unleashing the Strengths of Unlabeled Data in Pan-cancer Abdominal Organ Quantification: the FLARE22 Challenge

Quantitative organ assessment is an essential step in automated abdominal disease diagnosis and treatment planning. Artificial intelligence (AI) has shown great potential to automatize this process. However, most existing AI algorithms rely on many expert annotations and lack a comprehensive evaluation of accuracy and efficiency in real-world multinational settings. To overcome these limitations, we organized the FLARE 2022 Challenge, the largest abdominal organ analysis challenge to date, to benchmark fast, low-resource, accurate, annotation-efficient, and generalized AI algorithms. We constructed an intercontinental and multinational dataset from more than 50 medical groups, including Computed Tomography (CT) scans with different races, diseases, phases, and manufacturers. We independently validated that a set of AI algorithms achieved a median Dice Similarity Coefficient (DSC) of 90.0\% by using 50 labeled scans and 2000 unlabeled scans, which can significantly reduce annotation requirements. The best-performing algorithms successfully generalized to holdout external validation sets, achieving a median DSC of 89.5\%, 90.9\%, and 88.3\% on North American, European, and Asian cohorts, respectively. They also enabled automatic extraction of key organ biology features, which was labor-intensive with traditional manual measurements. This opens the potential to use unlabeled data to boost performance and alleviate annotation shortages for modern AI models.

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arXiv2023

FedIIC: Towards Robust Federated Learning for Class-Imbalanced Medical Image Classification

Federated learning (FL), training deep models from decentralized data without privacy leakage, has shown great potential in medical image computing recently. However, considering the ubiquitous class imbalance in medical data, FL can exhibit performance degradation, especially for minority classes (e.g. rare diseases). Existing methods towards this problem mainly focus on training a balanced classifier to eliminate class prior bias among classes, but neglect to explore better representation to facilitate classification performance. In this paper, we present a privacy-preserving FL method named FedIIC to combat class imbalance from two perspectives: feature learning and classifier learning. In feature learning, two levels of contrastive learning are designed to extract better class-specific features with imbalanced data in FL. In classifier learning, per-class margins are dynamically set according to real-time difficulty and class priors, which helps the model learn classes equally. Experimental results on publicly-available datasets demonstrate the superior performance of FedIIC in dealing with both real-world and simulated multi-source medical imaging data under class imbalance. Code is available at https://github.com/wnn2000/FedIIC.

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arXiv2023

GSMorph: Gradient Surgery for cine-MRI Cardiac Deformable Registration

Deep learning-based deformable registration methods have been widely investigated in diverse medical applications. Learning-based deformable registration relies on weighted objective functions trading off registration accuracy and smoothness of the deformation field. Therefore, they inevitably require tuning the hyperparameter for optimal registration performance. Tuning the hyperparameters is highly computationally expensive and introduces undesired dependencies on domain knowledge. In this study, we construct a registration model based on the gradient surgery mechanism, named GSMorph, to achieve a hyperparameter-free balance on multiple losses. In GSMorph, we reformulate the optimization procedure by projecting the gradient of similarity loss orthogonally to the plane associated with the smoothness constraint, rather than additionally introducing a hyperparameter to balance these two competing terms. Furthermore, our method is model-agnostic and can be merged into any deep registration network without introducing extra parameters or slowing down inference. In this study, We compared our method with state-of-the-art (SOTA) deformable registration approaches over two publicly available cardiac MRI datasets. GSMorph proves superior to five SOTA learning-based registration models and two conventional registration techniques, SyN and Demons, on both registration accuracy and smoothness.

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arXiv2023

Multi-IMU with Online Self-Consistency for Freehand 3D Ultrasound Reconstruction

Ultrasound (US) imaging is a popular tool in clinical diagnosis, offering safety, repeatability, and real-time capabilities. Freehand 3D US is a technique that provides a deeper understanding of scanned regions without increasing complexity. However, estimating elevation displacement and accumulation error remains challenging, making it difficult to infer the relative position using images alone. The addition of external lightweight sensors has been proposed to enhance reconstruction performance without adding complexity, which has been shown to be beneficial. We propose a novel online self-consistency network (OSCNet) using multiple inertial measurement units (IMUs) to improve reconstruction performance. OSCNet utilizes a modal-level self-supervised strategy to fuse multiple IMU information and reduce differences between reconstruction results obtained from each IMU data. Additionally, a sequence-level self-consistency strategy is proposed to improve the hierarchical consistency of prediction results among the scanning sequence and its sub-sequences. Experiments on large-scale arm and carotid datasets with multiple scanning tactics demonstrate that our OSCNet outperforms previous methods, achieving state-of-the-art reconstruction performance.

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arXiv2023

FreeCOS: Self-Supervised Learning from Fractals and Unlabeled Images for Curvilinear Object Segmentation

Curvilinear object segmentation is critical for many applications. However, manually annotating curvilinear objects is very time-consuming and error-prone, yielding insufficiently available annotated datasets for existing supervised methods and domain adaptation methods. This paper proposes a self-supervised curvilinear object segmentation method that learns robust and distinctive features from fractals and unlabeled images (FreeCOS). The key contributions include a novel Fractal-FDA synthesis (FFS) module and a geometric information alignment (GIA) approach. FFS generates curvilinear structures based on the parametric Fractal L-system and integrates the generated structures into unlabeled images to obtain synthetic training images via Fourier Domain Adaptation. GIA reduces the intensity differences between the synthetic and unlabeled images by comparing the intensity order of a given pixel to the values of its nearby neighbors. Such image alignment can explicitly remove the dependency on absolute intensity values and enhance the inherent geometric characteristics which are common in both synthetic and real images. In addition, GIA aligns features of synthetic and real images via the prediction space adaptation loss (PSAL) and the curvilinear mask contrastive loss (CMCL). Extensive experimental results on four public datasets, i.e., XCAD, DRIVE, STARE and CrackTree demonstrate that our method outperforms the state-of-the-art unsupervised methods, self-supervised methods and traditional methods by a large margin. The source code of this work is available at https://github.com/TY-Shi/FreeCOS.

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arXiv2023

An image segmentation algorithm based on multi-scale feature pyramid network

Medical image segmentation is particularly critical as a prerequisite for relevant quantitative analysis in the treatment of clinical diseases. For example, in clinical cervical cancer radiotherapy, after acquiring subabdominal MRI images, a fast and accurate image segmentation of organs and tumors in MRI images can optimize the clinical radiotherapy process, whereas traditional approaches use manual annotation by specialist doctors, which is time-consuming and laborious, therefore, automatic organ segmentation of subabdominal MRI images is a valuable research topic.

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arXiv2023

Biologically Inspired Dynamic Thresholds for Spiking Neural Networks

The dynamic membrane potential threshold, as one of the essential properties of a biological neuron, is a spontaneous regulation mechanism that maintains neuronal homeostasis, i.e., the constant overall spiking firing rate of a neuron. As such, the neuron firing rate is regulated by a dynamic spiking threshold, which has been extensively studied in biology. Existing work in the machine learning community does not employ bioinspired spiking threshold schemes. This work aims at bridging this gap by introducing a novel bioinspired dynamic energy-temporal threshold (BDETT) scheme for spiking neural networks (SNNs). The proposed BDETT scheme mirrors two bioplausible observations: a dynamic threshold has 1) a positive correlation with the average membrane potential and 2) a negative correlation with the preceding rate of depolarization. We validate the effectiveness of the proposed BDETT on robot obstacle avoidance and continuous control tasks under both normal conditions and various degraded conditions, including noisy observations, weights, and dynamic environments. We find that the BDETT outperforms existing static and heuristic threshold approaches by significant margins in all tested conditions, and we confirm that the proposed bioinspired dynamic threshold scheme offers homeostasis to SNNs in complex real-world tasks.

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arXiv2023

Dual-view Correlation Hybrid Attention Network for Robust Holistic Mammogram Classification

Mammogram image is important for breast cancer screening, and typically obtained in a dual-view form, i.e., cranio-caudal (CC) and mediolateral oblique (MLO), to provide complementary information. However, previous methods mostly learn features from the two views independently, which violates the clinical knowledge and ignores the importance of dual-view correlation. In this paper, we propose a dual-view correlation hybrid attention network (DCHA-Net) for robust holistic mammogram classification. Specifically, DCHA-Net is carefully designed to extract and reinvent deep features for the two views, and meanwhile to maximize the underlying correlations between them. A hybrid attention module, consisting of local relation and non-local attention blocks, is proposed to alleviate the spatial misalignment of the paired views in the correlation maximization. A dual-view correlation loss is introduced to maximize the feature similarity between corresponding strip-like regions with equal distance to the chest wall, motivated by the fact that their features represent the same breast tissues, and thus should be highly-correlated. Experimental results on two public datasets, i.e., INbreast and CBIS-DDSM, demonstrate that DCHA-Net can well preserve and maximize feature correlations across views, and thus outperforms the state-of-the-arts for classifying a whole mammogram as malignant or not.

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arXiv2023

Inflated 3D Convolution-Transformer for Weakly-supervised Carotid Stenosis Grading with Ultrasound Videos

Localization of the narrowest position of the vessel and corresponding vessel and remnant vessel delineation in carotid ultrasound (US) are essential for carotid stenosis grading (CSG) in clinical practice. However, the pipeline is time-consuming and tough due to the ambiguous boundaries of plaque and temporal variation. To automatize this procedure, a large number of manual delineations are usually required, which is not only laborious but also not reliable given the annotation difficulty. In this study, we present the first video classification framework for automatic CSG. Our contribution is three-fold. First, to avoid the requirement of laborious and unreliable annotation, we propose a novel and effective video classification network for weakly-supervised CSG. Second, to ease the model training, we adopt an inflation strategy for the network, where pre-trained 2D convolution weights can be adapted into the 3D counterpart in our network for an effective warm start. Third, to enhance the feature discrimination of the video, we propose a novel attention-guided multi-dimension fusion (AMDF) transformer encoder to model and integrate global dependencies within and across spatial and temporal dimensions, where two lightweight cross-dimensional attention mechanisms are designed. Our approach is extensively validated on a large clinically collected carotid US video dataset, demonstrating state-of-the-art performance compared with strong competitors.

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arXiv2023

Out-of-domain GAN inversion via Invertibility Decomposition for Photo-Realistic Human Face Manipulation

The fidelity of Generative Adversarial Networks (GAN) inversion is impeded by Out-Of-Domain (OOD) areas (e.g., background, accessories) in the image. Detecting the OOD areas beyond the generation ability of the pre-trained model and blending these regions with the input image can enhance fidelity. The "invertibility mask" figures out these OOD areas, and existing methods predict the mask with the reconstruction error. However, the estimated mask is usually inaccurate due to the influence of the reconstruction error in the In-Domain (ID) area. In this paper, we propose a novel framework that enhances the fidelity of human face inversion by designing a new module to decompose the input images to ID and OOD partitions with invertibility masks. Unlike previous works, our invertibility detector is simultaneously learned with a spatial alignment module. We iteratively align the generated features to the input geometry and reduce the reconstruction error in the ID regions. Thus, the OOD areas are more distinguishable and can be precisely predicted. Then, we improve the fidelity of our results by blending the OOD areas from the input image with the ID GAN inversion results. Our method produces photo-realistic results for real-world human face image inversion and manipulation. Extensive experiments demonstrate our method's superiority over existing methods in the quality of GAN inversion and attribute manipulation.

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arXiv2023

Instructive Feature Enhancement for Dichotomous Medical Image Segmentation

Deep neural networks have been widely applied in dichotomous medical image segmentation (DMIS) of many anatomical structures in several modalities, achieving promising performance. However, existing networks tend to struggle with task-specific, heavy and complex designs to improve accuracy. They made little instructions to which feature channels would be more beneficial for segmentation, and that may be why the performance and universality of these segmentation models are hindered. In this study, we propose an instructive feature enhancement approach, namely IFE, to adaptively select feature channels with rich texture cues and strong discriminability to enhance raw features based on local curvature or global information entropy criteria. Being plug-and-play and applicable for diverse DMIS tasks, IFE encourages the model to focus on texture-rich features which are especially important for the ambiguous and challenging boundary identification, simultaneously achieving simplicity, universality, and certain interpretability. To evaluate the proposed IFE, we constructed the first large-scale DMIS dataset Cosmos55k, which contains 55,023 images from 7 modalities and 26 anatomical structures. Extensive experiments show that IFE can improve the performance of classic segmentation networks across different anatomies and modalities with only slight modifications. Code is available at https://github.com/yezi-66/IFE

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arXiv2023

Fourier Test-time Adaptation with Multi-level Consistency for Robust Classification

Deep classifiers may encounter significant performance degradation when processing unseen testing data from varying centers, vendors, and protocols. Ensuring the robustness of deep models against these domain shifts is crucial for their widespread clinical application. In this study, we propose a novel approach called Fourier Test-time Adaptation (FTTA), which employs a dual-adaptation design to integrate input and model tuning, thereby jointly improving the model robustness. The main idea of FTTA is to build a reliable multi-level consistency measurement of paired inputs for achieving self-correction of prediction. Our contribution is two-fold. First, we encourage consistency in global features and local attention maps between the two transformed images of the same input. Here, the transformation refers to Fourier-based input adaptation, which can transfer one unseen image into source style to reduce the domain gap. Furthermore, we leverage style-interpolated images to enhance the global and local features with learnable parameters, which can smooth the consistency measurement and accelerate convergence. Second, we introduce a regularization technique that utilizes style interpolation consistency in the frequency space to encourage self-consistency in the logit space of the model output. This regularization provides strong self-supervised signals for robustness enhancement. FTTA was extensively validated on three large classification datasets with different modalities and organs. Experimental results show that FTTA is general and outperforms other strong state-of-the-art methods.

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arXiv2023

Bidirectional Semi-supervised Dual-branch CNN for Robust 3D Reconstruction of Stereo Endoscopic Images via Adaptive Cross and Parallel Supervisions

Semi-supervised learning via teacher-student network can train a model effectively on a few labeled samples. It enables a student model to distill knowledge from the teacher's predictions of extra unlabeled data. However, such knowledge flow is typically unidirectional, having the performance vulnerable to the quality of teacher model. In this paper, we seek to robust 3D reconstruction of stereo endoscopic images by proposing a novel fashion of bidirectional learning between two learners, each of which can play both roles of teacher and student concurrently. Specifically, we introduce two self-supervisions, i.e., Adaptive Cross Supervision (ACS) and Adaptive Parallel Supervision (APS), to learn a dual-branch convolutional neural network. The two branches predict two different disparity probability distributions for the same position, and output their expectations as disparity values. The learned knowledge flows across branches along two directions: a cross direction (disparity guides distribution in ACS) and a parallel direction (disparity guides disparity in APS). Moreover, each branch also learns confidences to dynamically refine its provided supervisions. In ACS, the predicted disparity is softened into a unimodal distribution, and the lower the confidence, the smoother the distribution. In APS, the incorrect predictions are suppressed by lowering the weights of those with low confidence. With the adaptive bidirectional learning, the two branches enjoy well-tuned supervisions, and eventually converge on a consistent and more accurate disparity estimation. The extensive and comprehensive experimental results on four public datasets demonstrate our superior performance over other state-of-the-arts with a relative decrease of averaged disparity error by at least 9.76%.

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arXiv2023

Frame-Event Alignment and Fusion Network for High Frame Rate Tracking

Most existing RGB-based trackers target low frame rate benchmarks of around 30 frames per second. This setting restricts the tracker's functionality in the real world, especially for fast motion. Event-based cameras as bioinspired sensors provide considerable potential for high frame rate tracking due to their high temporal resolution. However, event-based cameras cannot offer fine-grained texture information like conventional cameras. This unique complementarity motivates us to combine conventional frames and events for high frame rate object tracking under various challenging conditions. Inthispaper, we propose an end-to-end network consisting of multi-modality alignment and fusion modules to effectively combine meaningful information from both modalities at different measurement rates. The alignment module is responsible for cross-style and cross-frame-rate alignment between frame and event modalities under the guidance of the moving cues furnished by events. While the fusion module is accountable for emphasizing valuable features and suppressing noise information by the mutual complement between the two modalities. Extensive experiments show that the proposed approach outperforms state-of-the-art trackers by a significant margin in high frame rate tracking. With the FE240hz dataset, our approach achieves high frame rate tracking up to 240Hz.

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arXiv2023

Real-time 6K Image Rescaling with Rate-distortion Optimization

Contemporary image rescaling aims at embedding a high-resolution (HR) image into a low-resolution (LR) thumbnail image that contains embedded information for HR image reconstruction. Unlike traditional image super-resolution, this enables high-fidelity HR image restoration faithful to the original one, given the embedded information in the LR thumbnail. However, state-of-the-art image rescaling methods do not optimize the LR image file size for efficient sharing and fall short of real-time performance for ultra-high-resolution (e.g., 6K) image reconstruction. To address these two challenges, we propose a novel framework (HyperThumbnail) for real-time 6K rate-distortion-aware image rescaling. Our framework first embeds an HR image into a JPEG LR thumbnail by an encoder with our proposed quantization prediction module, which minimizes the file size of the embedding LR JPEG thumbnail while maximizing HR reconstruction quality. Then, an efficient frequency-aware decoder reconstructs a high-fidelity HR image from the LR one in real time. Extensive experiments demonstrate that our framework outperforms previous image rescaling baselines in rate-distortion performance and can perform 6K image reconstruction in real time.

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arXiv2023

Affinity Feature Strengthening for Accurate, Complete and Robust Vessel Segmentation

Vessel segmentation is crucial in many medical image applications, such as detecting coronary stenoses, retinal vessel diseases and brain aneurysms. However, achieving high pixel-wise accuracy, complete topology structure and robustness to various contrast variations are critical and challenging, and most existing methods focus only on achieving one or two of these aspects. In this paper, we present a novel approach, the affinity feature strengthening network (AFN), which jointly models geometry and refines pixel-wise segmentation features using a contrast-insensitive, multiscale affinity approach. Specifically, we compute a multiscale affinity field for each pixel, capturing its semantic relationships with neighboring pixels in the predicted mask image. This field represents the local geometry of vessel segments of different sizes, allowing us to learn spatial- and scale-aware adaptive weights to strengthen vessel features. We evaluate our AFN on four different types of vascular datasets: X-ray angiography coronary vessel dataset (XCAD), portal vein dataset (PV), digital subtraction angiography cerebrovascular vessel dataset (DSA) and retinal vessel dataset (DRIVE). Extensive experimental results demonstrate that our AFN outperforms the state-of-the-art methods in terms of both higher accuracy and topological metrics, while also being more robust to various contrast changes. The source code of this work is available at https://github.com/TY-Shi/AFN.

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