arXiv subjects

Xin Yang

Publications and source records attributed to Xin Yang.

At least 343 records · Page 19Linked to original sources

arXiv2021

Flip Learning: Erase to Segment

Nodule segmentation from breast ultrasound images is challenging yet essential for the diagnosis. Weakly-supervised segmentation (WSS) can help reduce time-consuming and cumbersome manual annotation. Unlike existing weakly-supervised approaches, in this study, we propose a novel and general WSS framework called Flip Learning, which only needs the box annotation. Specifically, the target in the label box will be erased gradually to flip the classification tag, and the erased region will be considered as the segmentation result finally. Our contribution is three-fold. First, our proposed approach erases on superpixel level using a Multi-agent Reinforcement Learning framework to exploit the prior boundary knowledge and accelerate the learning process. Second, we design two rewards: classification score and intensity distribution reward, to avoid under- and over-segmentation, respectively. Third, we adopt a coarse-to-fine learning strategy to reduce the residual errors and improve the segmentation performance. Extensively validated on a large dataset, our proposed approach achieves competitive performance and shows great potential to narrow the gap between fully-supervised and weakly-supervised learning.

cs.CV↗

arXiv2021

Style Curriculum Learning for Robust Medical Image Segmentation

The performance of deep segmentation models often degrades due to distribution shifts in image intensities between the training and test data sets. This is particularly pronounced in multi-centre studies involving data acquired using multi-vendor scanners, with variations in acquisition protocols. It is challenging to address this degradation because the shift is often not known \textit{a priori} and hence difficult to model. We propose a novel framework to ensure robust segmentation in the presence of such distribution shifts. Our contribution is three-fold. First, inspired by the spirit of curriculum learning, we design a novel style curriculum to train the segmentation models using an easy-to-hard mode. A style transfer model with style fusion is employed to generate the curriculum samples. Gradually focusing on complex and adversarial style samples can significantly boost the robustness of the models. Second, instead of subjectively defining the curriculum complexity, we adopt an automated gradient manipulation method to control the hard and adversarial sample generation process. Third, we propose the Local Gradient Sign strategy to aggregate the gradient locally and stabilise training during gradient manipulation. The proposed framework can generalise to unknown distribution without using any target data. Extensive experiments on the public M\&Ms Challenge dataset demonstrate that our proposed framework can generalise deep models well to unknown distributions and achieve significant improvements in segmentation accuracy.

eess.IV↗

arXiv2021

Prior-Induced Information Alignment for Image Matting

Image matting is an ill-posed problem that aims to estimate the opacity of foreground pixels in an image. However, most existing deep learning-based methods still suffer from the coarse-grained details. In general, these algorithms are incapable of felicitously distinguishing the degree of exploration between deterministic domains (certain FG and BG pixels) and undetermined domains (uncertain in-between pixels), or inevitably lose information in the continuous sampling process, leading to a sub-optimal result. In this paper, we propose a novel network named Prior-Induced Information Alignment Matting Network (PIIAMatting), which can efficiently model the distinction of pixel-wise response maps and the correlation of layer-wise feature maps. It mainly consists of a Dynamic Gaussian Modulation mechanism (DGM) and an Information Alignment strategy (IA). Specifically, the DGM can dynamically acquire a pixel-wise domain response map learned from the prior distribution. The response map can present the relationship between the opacity variation and the convergence process during training. On the other hand, the IA comprises an Information Match Module (IMM) and an Information Aggregation Module (IAM), jointly scheduled to match and aggregate the adjacent layer-wise features adaptively. Besides, we also develop a Multi-Scale Refinement (MSR) module to integrate multi-scale receptive field information at the refinement stage to recover the fluctuating appearance details. Extensive quantitative and qualitative evaluations demonstrate that the proposed PIIAMatting performs favourably against state-of-the-art image matting methods on the Alphamatting.com, Composition-1K and Distinctions-646 dataset.

cs.CV↗

arXiv2021

The Numerical Unified Transform Method for the Nonlinear Schrödinger equation on the half-line

We implement the Numerical Unified Transform Method to solve the Nonlinear Schrödinger equation on the half-line. For so-called linearizable boundary conditions, the method solves the half-line problems with comparable complexity as the Numerical Inverse Scattering Transform solves whole-line problems. In particular, the method computes the solution at any $x$ and $t$ without spatial discretization or time stepping. Contour deformations based on the method of nonlinear steepest descent are used so that the method's computational cost does not increase for large $x,t$ and the method is more accurate as $x,t$ increase. Our ideas also apply to some cases where the boundary conditions are not linearizable.

math.NA↗

arXiv2021

Joint Landmark and Structure Learning for Automatic Evaluation of Developmental Dysplasia of the Hip

The ultrasound (US) screening of the infant hip is vital for the early diagnosis of developmental dysplasia of the hip (DDH). The US diagnosis of DDH refers to measuring alpha and beta angles that quantify hip joint development. These two angles are calculated from key anatomical landmarks and structures of the hip. However, this measurement process is not trivial for sonographers and usually requires a thorough understanding of complex anatomical structures. In this study, we propose a multi-task framework to learn the relationships among landmarks and structures jointly and automatically evaluate DDH. Our multi-task networks are equipped with three novel modules. Firstly, we adopt Mask R-CNN as the basic framework to detect and segment key anatomical structures and add one landmark detection branch to form a new multi-task framework. Secondly, we propose a novel shape similarity loss to refine the incomplete anatomical structure prediction robustly and accurately. Thirdly, we further incorporate the landmark-structure consistent prior to ensure the consistency of the bony rim estimated from the segmented structure and the detected landmark. In our experiments, 1,231 US images of the infant hip from 632 patients are collected, of which 247 images from 126 patients are tested. The average errors in alpha and beta angles are 2.221 degrees and 2.899 degrees. About 93% and 85% estimates of alpha and beta angles have errors less than 5 degrees, respectively. Experimental results demonstrate that the proposed method can accurately and robustly realize the automatic evaluation of DDH, showing great potential for clinical application.

eess.IV↗

arXiv2021

Vertical Federated Learning without Revealing Intersection Membership

Vertical Federated Learning (vFL) allows multiple parties that own different attributes (e.g. features and labels) of the same data entity (e.g. a person) to jointly train a model. To prepare the training data, vFL needs to identify the common data entities shared by all parties. It is usually achieved by Private Set Intersection (PSI) which identifies the intersection of training samples from all parties by using personal identifiable information (e.g. email) as sample IDs to align data instances. As a result, PSI would make sample IDs of the intersection visible to all parties, and therefore each party can know that the data entities shown in the intersection also appear in the other parties, i.e. intersection membership. However, in many real-world privacy-sensitive organizations, e.g. banks and hospitals, revealing membership of their data entities is prohibited. In this paper, we propose a vFL framework based on Private Set Union (PSU) that allows each party to keep sensitive membership information to itself. Instead of identifying the intersection of all training samples, our PSU protocol generates the union of samples as training instances. In addition, we propose strategies to generate synthetic features and labels to handle samples that belong to the union but not the intersection. Through extensive experiments on two real-world datasets, we show our framework can protect the privacy of the intersection membership while maintaining the model utility.

cs.LG↗

arXiv2021

Deriving Autism Spectrum Disorder Functional Networks from RS-FMRI Data using Group ICA and Dictionary Learning

The objective of this study is to derive functional networks for the autism spectrum disorder (ASD) population using the group ICA and dictionary learning model together and to classify ASD and typically developing (TD) participants using the functional connectivity calculated from the derived functional networks. In our experiments, the ASD functional networks were derived from resting-state functional magnetic resonance imaging (rs-fMRI) data. We downloaded a total of 120 training samples, including 58 ASD and 62 TD participants, which were obtained from the public repository: Autism Brain Imaging Data Exchange I (ABIDE I). Our methodology and results have five main parts. First, we utilize a group ICA model to extract functional networks from the ASD group and rank the top 20 regions of interest (ROIs). Second, we utilize a dictionary learning model to extract functional networks from the ASD group and rank the top 20 ROIs. Third, we merged the 40 selected ROIs from the two models together as the ASD functional networks. Fourth, we generate three corresponding masks based on the 20 selected ROIs from group ICA, the 20 ROIs selected from dictionary learning, and the 40 combined ROIs selected from both. Finally, we extract ROIs for all training samples using the above three masks, and the calculated functional connectivity was used as features for ASD and TD classification. The classification results showed that the functional networks derived from ICA and dictionary learning together outperform those derived from a single ICA model or a single dictionary learning model.

q-bio.NC↗

arXiv2021

Searching Collaborative Agents for Multi-plane Localization in 3D Ultrasound

3D ultrasound (US) has become prevalent due to its rich spatial and diagnostic information not contained in 2D US. Moreover, 3D US can contain multiple standard planes (SPs) in one shot. Thus, automatically localizing SPs in 3D US has the potential to improve user-independence and scanning-efficiency. However, manual SP localization in 3D US is challenging because of the low image quality, huge search space and large anatomical variability. In this work, we propose a novel multi-agent reinforcement learning (MARL) framework to simultaneously localize multiple SPs in 3D US. Our contribution is four-fold. First, our proposed method is general and it can accurately localize multiple SPs in different challenging US datasets. Second, we equip the MARL system with a recurrent neural network (RNN) based collaborative module, which can strengthen the communication among agents and learn the spatial relationship among planes effectively. Third, we explore to adopt the neural architecture search (NAS) to automatically design the network architecture of both the agents and the collaborative module. Last, we believe we are the first to realize automatic SP localization in pelvic US volumes, and note that our approach can handle both normal and abnormal uterus cases. Extensively validated on two challenging datasets of the uterus and fetal brain, our proposed method achieves the average localization accuracy of 7.03 degrees/1.59mm and 9.75 degrees/1.19mm. Experimental results show that our light-weight MARL model has higher accuracy than state-of-the-art methods.

cs.CV↗

arXiv2021

Learn Fine-grained Adaptive Loss for Multiple Anatomical Landmark Detection in Medical Images

Automatic and accurate detection of anatomical landmarks is an essential operation in medical image analysis with a multitude of applications. Recent deep learning methods have improved results by directly encoding the appearance of the captured anatomy with the likelihood maps (i.e., heatmaps). However, most current solutions overlook another essence of heatmap regression, the objective metric for regressing target heatmaps and rely on hand-crafted heuristics to set the target precision, thus being usually cumbersome and task-specific. In this paper, we propose a novel learning-to-learn framework for landmark detection to optimize the neural network and the target precision simultaneously. The pivot of this work is to leverage the reinforcement learning (RL) framework to search objective metrics for regressing multiple heatmaps dynamically during the training process, thus avoiding setting problem-specific target precision. We also introduce an early-stop strategy for active termination of the RL agent's interaction that adapts the optimal precision for separate targets considering exploration-exploitation tradeoffs. This approach shows better stability in training and improved localization accuracy in inference. Extensive experimental results on two different applications of landmark localization: 1) our in-house prenatal ultrasound (US) dataset and 2) the publicly available dataset of cephalometric X-Ray landmark detection, demonstrate the effectiveness of our proposed method. Our proposed framework is general and shows the potential to improve the efficiency of anatomical landmark detection.

cs.CV↗

arXiv2021

FL-NTK: A Neural Tangent Kernel-based Framework for Federated Learning Convergence Analysis

Federated Learning (FL) is an emerging learning scheme that allows different distributed clients to train deep neural networks together without data sharing. Neural networks have become popular due to their unprecedented success. To the best of our knowledge, the theoretical guarantees of FL concerning neural networks with explicit forms and multi-step updates are unexplored. Nevertheless, training analysis of neural networks in FL is non-trivial for two reasons: first, the objective loss function we are optimizing is non-smooth and non-convex, and second, we are even not updating in the gradient direction. Existing convergence results for gradient descent-based methods heavily rely on the fact that the gradient direction is used for updating. This paper presents a new class of convergence analysis for FL, Federated Learning Neural Tangent Kernel (FL-NTK), which corresponds to overparamterized ReLU neural networks trained by gradient descent in FL and is inspired by the analysis in Neural Tangent Kernel (NTK). Theoretically, FL-NTK converges to a global-optimal solution at a linear rate with properly tuned learning parameters. Furthermore, with proper distributional assumptions, FL-NTK can also achieve good generalization.

cs.LG↗

arXiv2021

Camouflaged Object Segmentation with Distraction Mining

Camouflaged object segmentation (COS) aims to identify objects that are "perfectly" assimilate into their surroundings, which has a wide range of valuable applications. The key challenge of COS is that there exist high intrinsic similarities between the candidate objects and noise background. In this paper, we strive to embrace challenges towards effective and efficient COS. To this end, we develop a bio-inspired framework, termed Positioning and Focus Network (PFNet), which mimics the process of predation in nature. Specifically, our PFNet contains two key modules, i.e., the positioning module (PM) and the focus module (FM). The PM is designed to mimic the detection process in predation for positioning the potential target objects from a global perspective and the FM is then used to perform the identification process in predation for progressively refining the coarse prediction via focusing on the ambiguous regions. Notably, in the FM, we develop a novel distraction mining strategy for distraction discovery and removal, to benefit the performance of estimation. Extensive experiments demonstrate that our PFNet runs in real-time (72 FPS) and significantly outperforms 18 cutting-edge models on three challenging datasets under four standard metrics.

cs.CV↗

arXiv2021

A Two-Stage Attentive Network for Single Image Super-Resolution

Recently, deep convolutional neural networks (CNNs) have been widely explored in single image super-resolution (SISR) and contribute remarkable progress. However, most of the existing CNNs-based SISR methods do not adequately explore contextual information in the feature extraction stage and pay little attention to the final high-resolution (HR) image reconstruction step, hence hindering the desired SR performance. To address the above two issues, in this paper, we propose a two-stage attentive network (TSAN) for accurate SISR in a coarse-to-fine manner. Specifically, we design a novel multi-context attentive block (MCAB) to make the network focus on more informative contextual features. Moreover, we present an essential refined attention block (RAB) which could explore useful cues in HR space for reconstructing fine-detailed HR image. Extensive evaluations on four benchmark datasets demonstrate the efficacy of our proposed TSAN in terms of quantitative metrics and visual effects. Code is available at https://github.com/Jee-King/TSAN.

eess.IV↗

arXiv2021

A Deep Attentive Convolutional Neural Network for Automatic Cortical Plate Segmentation in Fetal MRI

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and time-consuming. Automatic segmentation of the cortical plate, on the other hand, is challenged by the relatively low resolution of the reconstructed fetal brain MRI scans compared to the thin structure of the cortical plate, partial voluming, and the wide range of variations in the morphology of the cortical plate as the brain matures during gestation. To reduce the burden of manual refinement of segmentations, we have developed a new and powerful deep learning segmentation method. Our method exploits new deep attentive modules with mixed kernel convolutions within a fully convolutional neural network architecture that utilizes deep supervision and residual connections. We evaluated our method quantitatively based on several performance measures and expert evaluations. Results show that our method outperforms several state-of-the-art deep models for segmentation, as well as a state-of-the-art multi-atlas segmentation technique. We achieved average Dice similarity coefficient of 0.87, average Hausdorff distance of 0.96 mm, and average symmetric surface difference of 0.28 mm on reconstructed fetal brain MRI scans of fetuses scanned in the gestational age range of 16 to 39 weeks. With a computation time of less than 1 minute per fetal brain, our method can facilitate and accelerate large-scale studies on normal and altered fetal brain cortical maturation and folding.

cs.CV↗

arXiv2021

Smart Scribbles for Image Mating

Image matting is an ill-posed problem that usually requires additional user input, such as trimaps or scribbles. Drawing a fne trimap requires a large amount of user effort, while using scribbles can hardly obtain satisfactory alpha mattes for non-professional users. Some recent deep learning-based matting networks rely on large-scale composite datasets for training to improve performance, resulting in the occasional appearance of obvious artifacts when processing natural images. In this article, we explore the intrinsic relationship between user input and alpha mattes and strike a balance between user effort and the quality of alpha mattes. In particular, we propose an interactive framework, referred to as smart scribbles, to guide users to draw few scribbles on the input images to produce high-quality alpha mattes. It frst infers the most informative regions of an image for drawing scribbles to indicate different categories (foreground, background, or unknown) and then spreads these scribbles (i.e., the category labels) to the rest of the image via our well-designed two-phase propagation. Both neighboring low-level afnities and high-level semantic features are considered during the propagation process. Our method can be optimized without large-scale matting datasets and exhibits more universality in real situations. Extensive experiments demonstrate that smart scribbles can produce more accurate alpha mattes with reduced additional input, compared to the state-of-the-art matting methods.

cs.CV↗

arXiv2021

Agent with Warm Start and Adaptive Dynamic Termination for Plane Localization in 3D Ultrasound

Accurate standard plane (SP) localization is the fundamental step for prenatal ultrasound (US) diagnosis. Typically, dozens of US SPs are collected to determine the clinical diagnosis. 2D US has to perform scanning for each SP, which is time-consuming and operator-dependent. While 3D US containing multiple SPs in one shot has the inherent advantages of less user-dependency and more efficiency. Automatically locating SP in 3D US is very challenging due to the huge search space and large fetal posture variations. Our previous study proposed a deep reinforcement learning (RL) framework with an alignment module and active termination to localize SPs in 3D US automatically. However, termination of agent search in RL is important and affects the practical deployment. In this study, we enhance our previous RL framework with a newly designed adaptive dynamic termination to enable an early stop for the agent searching, saving at most 67% inference time, thus boosting the accuracy and efficiency of the RL framework at the same time. Besides, we validate the effectiveness and generalizability of our algorithm extensively on our in-house multi-organ datasets containing 433 fetal brain volumes, 519 fetal abdomen volumes, and 683 uterus volumes. Our approach achieves localization error of 2.52mm/10.26 degrees, 2.48mm/10.39 degrees, 2.02mm/10.48 degrees, 2.00mm/14.57 degrees, 2.61mm/9.71 degrees, 3.09mm/9.58 degrees, 1.49mm/7.54 degrees for the transcerebellar, transventricular, transthalamic planes in fetal brain, abdominal plane in fetal abdomen, and mid-sagittal, transverse and coronal planes in uterus, respectively. Experimental results show that our method is general and has the potential to improve the efficiency and standardization of US scanning.

eess.IV↗

arXiv2021

Manipulate the Electronic State of Mott Iridate Superlattice through Protonation Induced Electron-Filling

Spin-orbit-coupled Mott iridates show great similarity with parent compounds of superconducting cuprates, attracting extensive research interests especially for their electron-doped states. However, previous experiments are largely limited within a small doping range due to the absence of effective dopants, and therefore the electron-doped phase diagram remains elusive. Here we utilize an ionic-liquid-gating induced protonation method to achieve electron-doping into a 5d Mott-insulator built with SrIrO3/SrTiO3 superlattice, and achieve a systematic mapping of its electron-doped phase diagram with the evolution of the iridium valence state from 4+ to 3+, equivalent to doping of one electron per iridium ion. Along increasing doping level, the parent Mott-insulator is first turned into a localized metallic state with gradually suppressed magnetic ordering, and then further evolved into a nonmagnetic band insulating state. This work forms an important step forward for the study of electron-doped Mott iridate systems, and the strategy of manipulating the band filling in an artificially designed superlattice structure can be readily extended into other systems with more exotic states to explore.

cond-mat.str-el↗

arXiv2021

Multi-scale Information Assembly for Image Matting

Image matting is a long-standing problem in computer graphics and vision, mostly identified as the accurate estimation of the foreground in input images. We argue that the foreground objects can be represented by different-level information, including the central bodies, large-grained boundaries, refined details, etc. Based on this observation, in this paper, we propose a multi-scale information assembly framework (MSIA-matte) to pull out high-quality alpha mattes from single RGB images. Technically speaking, given an input image, we extract advanced semantics as our subject content and retain initial CNN features to encode different-level foreground expression, then combine them by our well-designed information assembly strategy. Extensive experiments can prove the effectiveness of the proposed MSIA-matte, and we can achieve state-of-the-art performance compared to most existing matting networks.

cs.CV↗

arXiv2021

Automatic Comic Generation with Stylistic Multi-page Layouts and Emotion-driven Text Balloon Generation

In this paper, we propose a fully automatic system for generating comic books from videos without any human intervention. Given an input video along with its subtitles, our approach first extracts informative keyframes by analyzing the subtitles, and stylizes keyframes into comic-style images. Then, we propose a novel automatic multi-page layout framework, which can allocate the images across multiple pages and synthesize visually interesting layouts based on the rich semantics of the images (e.g., importance and inter-image relation). Finally, as opposed to using the same type of balloon as in previous works, we propose an emotion-aware balloon generation method to create different types of word balloons by analyzing the emotion of subtitles and audios. Our method is able to vary balloon shapes and word sizes in balloons in response to different emotions, leading to more enriched reading experience. Once the balloons are generated, they are placed adjacent to their corresponding speakers via speaker detection. Our results show that our method, without requiring any user inputs, can generate high-quality comic pages with visually rich layouts and balloons. Our user studies also demonstrate that users prefer our generated results over those by state-of-the-art comic generation systems.

cs.CV↗