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Xinyu Nie

Publications and source records attributed to Xinyu Nie.

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Feynman Kac Reweighted Schrödinger Bridge Matching for Surface-Based Tau PET Harmonization

Tau positron emission tomography (PET) is widely used for the in vivo characterization of disease stage and progression in Alzheimer's disease (AD). With the adoption of multiple tau PET tracers including AV-1451, PI-2620, MK-6240 with different binding behaviors in various large-scale studies, there is a great need of effective harmonization methods to enable the cross-tracer integration of tau PET datasets. While previous methods such as CenTauR were proposed to standardize scalar tau PET measures, they are limited in accounting for the heterogeneity of tau pathology. In this work, we propose Feynman-Kac Reweighted Schrödinger Bridge Matching (FKRSBM), a surface-based framework for cross-tracer tau PET harmonization. FKRSBM learns a direct stochastic transport between tracer domains using Schrödinger Bridge matching, avoiding the Gaussian-prior routing used in diffusion-based translation. To promote biologically consistent transport, FKRSBM introduces an endpoint penalty favoring bridge pairings with matched tau-pathology status and implements it through a Feynman-Kac reweighted endpoint proposal. To preserve cortical organization, FKRSBM uses a spherical convolutional network for vertex-level harmonization on cortical surface meshes. In our experiments, we demonstrate our method by harmonizing Tau PET images acquired with the AV-1451 (n=1480) and PI-2620 (n=2458) tracers from two large-scale datasets. Compared to previous methods including ComBat, CycleGAN, Diffusion Model(DF), and unregularized Schrödinger Bridge Model(DSBM), the proposed FKRSBM method outperforms these baselines in subgroup-level alignment, tau-positivity consistency, and diagnostic classification while preserving subject-specific cortical topography of tau pathology. The code is available at: https://github.com/jianweizhang17/FKRSBM.

eess.IV

YOLO-RS: Remote Sensing Enhanced Crop Detection Methods

With the rapid development of remote sensing technology, crop classification and health detection based on deep learning have gradually become a research hotspot. However, the existing target detection methods show poor performance when dealing with small targets in remote sensing images, especially in the case of complex background and image mixing, which is difficult to meet the practical application requirementsite. To address this problem, a novel target detection model YOLO-RS is proposed in this paper. The model is based on the latest Yolov11 which significantly enhances the detection of small targets by introducing the Context Anchor Attention (CAA) mechanism and an efficient multi-field multi-scale feature fusion network. YOLO-RS adopts a bidirectional feature fusion strategy in the feature fusion process, which effectively enhances the model's performance in the detection of small targets. Small target detection. Meanwhile, the ACmix module at the end of the model backbone network solves the category imbalance problem by adaptively adjusting the contrast and sample mixing, thus enhancing the detection accuracy in complex scenes. In the experiments on the PDT remote sensing crop health detection dataset and the CWC crop classification dataset, YOLO-RS improves both the recall and the mean average precision (mAP) by about 2-3\% or so compared with the existing state-of-the-art methods, while the F1-score is also significantly improved. Moreover, the computational complexity of the model only increases by about 5.2 GFLOPs, indicating its significant advantages in both performance and efficiency. The experimental results validate the effectiveness and application potential of YOLO-RS in the task of detecting small targets in remote sensing images.

cs.CV