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Xiuyuan Wang

Publications and source records attributed to Xiuyuan Wang.

17 recordsLinked to original sources

Self-similar finite-time blowups with singular profiles of the generalized Constantin-Lax-Majda model: theoretical and numerical investigations

We investigate novel scenarios of self-similar finite-time blowups of the generalized Constantin-Lax-Majda model with a parameter $a$, which are induced by a new setting where the smooth initial data satisfy certain derivative degeneracy condition. In this setting, our numerical study reveals distinct self-similar blowup behaviors depending on the sign of $a$. For $a>0$, we observe one-scale self-similar blowups with regular profiles that have not been found in previous studies. In contrast, for $a\le 0$, we discover a novel two-scale self-similar blowup scenario where the outer profile converges to a singular function at the blowup time while the inner profile remains regular on a much smaller scale. Correspondingly, an $a$-parameterized family of singular self-similar profiles with explicit expressions are constructed for $a<0$ and shown to match nicely with the limiting profiles obtained in numerical simulation. In particular, for the specific case of $a=0$, we rigorously prove the convergence of the outer profile to an explicit singular function in self-similar coordinates. Furthermore, we demonstrate the two-scale nature of the blowup in this scenario by showing that the local inner profile behavior around the singularity point of the outer profile is governed by a traveling wave on a smaller scale. To support this observation, we rigorously establish the existence of such traveling wave solutions via a fixed-point method.

math.AP

Accelerated Mixing Time of Randomized Hamiltonian Monte Carlo

We show the Randomized Hamiltonian Monte Carlo (RHMC) algorithm has accelerated mixing time guarantees for sampling from log-concave probability distributions. RHMC proceeds by repeatedly simulating the continuous-time Hamiltonian dynamics for some random integration times, and resetting the velocity to be an independent Gaussian random variable between each simulation. We show that when the target distribution is log-concave and satisfies an $α$-Talagrand inequality (for example, if the target distribution is $α$-strongly log-concave), if we use a random integration time from either the triangular or the exponential distribution with mean $Θ(α^{-1/2})$, then RHMC converges exponentially fast in KL divergence, and the total integration time to reach error $\varepsilon$ in KL divergence scales as $O(α^{-1/2} \log(\varepsilon^{-1}))$. We also show that when the target distribution is log-concave, if we use a sequence of random integration times from the triangular distribution with exponentially increasing means, then the total integration time to reach error $\varepsilon$ in KL divergence scales as $O(\varepsilon^{-1/2})$. Our analysis relies on a bound on the average KL divergence along Hamiltonian dynamics, which is inspired by an analogous result on accelerated optimization methods based on Hamiltonian dynamics.

stat.ML

Exact Blowup Analysis for the Weak-Advection Hou--Li Model

We study self-similar singularity formation for the one-dimensional weak-advection Hou--Li model, a reduced model motivated by the axisymmetric Euler equations. In the periodic setting, we construct exact finite-time self-similar blowup solutions for $2/3<a<1$, with profiles that are neither focusing nor expanding. In the whole-space setting with a Neumann condition, we construct exact finite-time self-similar blowup solutions for the full range $0<a\leq1$, with profiles of focusing, non-expanding/non-focusing, or expanding form depending on the sign of the self-similar scaling parameter. The construction is based on a fixed-point formulation near the origin, followed by an ODE extension argument. We also establish regularity, asymptotic behavior, monotonicity properties of the profiles, and uniqueness up to the natural scaling invariance.

math.AP

Accelerated Convex Optimization via Hamiltonian Dynamics with Deterministic Integration Time

We develop Hamiltonian dynamics-based algorithms for smooth convex optimization that achieve accelerated rates of convergence. By exploiting contraction of averaged Hamiltonian flow trajectories rather than requiring contraction at trajectory endpoints, we show that Hamiltonian dynamics-based optimization methods admit deterministic and accelerated convergence guarantees, extending prior work that is limited to quadratic objectives or holds only in expectation. We analyze an idealized continuous-time algorithm and derive practical discrete-time implementations with optimal first-order complexity, thereby establishing Hamiltonian dynamics as a useful algorithmic primitive for deterministic accelerated convex optimization.

math.OC

A Symplectic Analysis of Alternating Mirror Descent

Motivated by understanding the behavior of the Alternating Mirror Descent (AMD) algorithm for bilinear zero-sum games, we study the discretization of continuous-time Hamiltonian flow via the symplectic Euler method. We provide a framework for analysis using results from Hamiltonian dynamics, Lie algebra, and symplectic numerical integrators, with an emphasis on the existence and properties of a conserved quantity, the modified Hamiltonian (MH), for the symplectic Euler method. We compute the MH in closed-form when the original Hamiltonian is a quadratic function, and show that it generally differs from the other conserved quantity known previously in that case. We derive new error bounds on the MH when truncated at orders in the stepsize in terms of the number of iterations, $K$, and use these bounds to show an improved $\mathcal{O}(K^{1/5})$ total regret bound and an $\mathcal{O}(K^{-4/5})$ duality gap of the average iterates for AMD. Finally, we propose a conjecture which, if true, would imply that the total regret for AMD scales as $\mathcal{O}\left(K^{\varepsilon}\right)$ and the duality gap of the average iterates as $\mathcal{O}\left(K^{-1+\varepsilon}\right)$ for any $\varepsilon>0$, and we can take $\varepsilon=0$ upon certain convergence conditions for the MH.

math.OC

Physically-Based Inverse Rendering Framework for PET Image Reconstruction

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of scene parameters. Inspired by this paradigm, we propose a physically-based inverse rendering (IR) framework, the first ever platform for PET image reconstruction using Dr.Jit, for PET image reconstruction. Our method integrates Monte Carlo sampling with an analytical projector in the forward rendering process to accurately model photon transport and physical process in the PET system. The emission image is iteratively optimized using voxel-wise gradients obtained via automatic differentiation, eliminating the need for manually derived update equations. The proposed framework was evaluated using both phantom studies and clinical brain PET data acquired from a Siemens Biograph mCT scanner. Implementing the Maximum Likelihood Expectation Maximization (MLEM) algorithm across both the CASToR toolkit and our IR framework, the IR reconstruction achieved a higher signal-to-noise ratio (SNR) and improved image quality compared to CASToR reconstructions. In clinical evaluation compared with the Siemens Biograph mCT platform, the IR reconstruction yielded higher hippocampal standardized uptake value ratios (SUVR) and gray-to-white matter ratios (GWR), indicating enhanced tissue contrast and the potential for more accurate tau localization and Braak staging in Alzheimer's disease assessment. The proposed IR framework offers a physically interpretable and extensible platform for high-fidelity PET image reconstruction, demonstrating strong performance in both phantom and real-world scenarios.

physics.med-ph

Exact self-similar finite-time blowup of the Hou-Luo model with smooth profiles

We show that the 1D Hou-Luo model on the real line admits exact self-similar finite-time blowup solutions with smooth self-similar profiles. The existence of these profiles is established via a fixed-point method that is purely analytic. We also prove that the profiles satisfy some monotonicity and convexity properties that were unknown before, and we give rigorous estimates on the algebraic decay rates of the profiles in the far field. Our result supplements the previous computer-assisted proof of self-similar finite-time blowup for the Hou-Luo model with finer characterizations of the profiles.

math.AP

Multi-scale self-similar finite-time blowups of the Constantin-Lax-Majda model for the 3D Euler equations

We construct a new class of asymptotically self-similar finite-time blowups that have two collapsing spatial scales for the 1D Constantin-Lax-Majda model. The larger spatial scale measures the decreasing distance between the bulk of the solution and the eventual blowup point, while the smaller scale measures the shrinking size of the bulk of the solution. Similar multi-scale blowup phenomena have recently been discovered for many higher dimensional equations. Our study may provide some understanding of the common mechanism behind these multi-scale blowups.

math.AP

On the Convergence of Min-Max Langevin Dynamics and Algorithm

We study zero-sum games in the space of probability distributions over the Euclidean space $\mathbb{R}^d$ with entropy regularization, in the setting when the interaction function between the players is smooth and strongly convex-strongly concave. We prove an exponential convergence guarantee for the mean-field min-max Langevin dynamics to compute the equilibrium distribution of the zero-sum game. We also study the finite-particle approximation of the mean-field min-max Langevin dynamics, both in continuous and discrete times. We prove biased convergence guarantees for the continuous-time finite-particle min-max Langevin dynamics to the stationary mean-field equilibrium distribution with an explicit bias term which does not scale with the number of particles. We also prove biased convergence guarantees for the discrete-time finite-particle min-max Langevin algorithm to the stationary mean-field equilibrium distribution with an additional bias term which scales with the step size and the number of particles. This provides an explicit iteration complexity for the average particle along the finite-particle algorithm to approximately compute the equilibrium distribution of the zero-sum game.

cs.GT

Self-similar finite-time blowups with smooth profiles of the generalized Constantin-Lax-Majda model

We show that the $a$-parameterized family of the generalized Constantin-Lax-Majda model, also known as the Okamoto-Sakajo-Wunsch model, admits exact self-similar finite-time blowup solutions with interiorly smooth profiles for all $a\leq 1$. Depending on the value of $a$, these self-similar profiles are either smooth on the whole real line or compactly supported and smooth in the interior of their closed supports. The existence of these profiles is proved in a consistent way by considering the fixed-point problem of an $a$-dependent nonlinear map, based on which detailed characterizations of their regularity, monotonicity, and far-field decay rates are established. Our work unifies existing results for some discrete values of $a$ and also explains previous numerical observations for a wide range of $a$.

math.AP

DARTS: DenseUnet-based Automatic Rapid Tool for brain Segmentation

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain segmentation software, widespread clinical adoption of volumetric analysis has been hindered due to processing times and reliance on manual corrections. Here, we extend the use of deep learning models from proof-of-concept, as previously reported, to present a comprehensive segmentation of cortical and deep gray matter brain structures matching the standard regions of aseg+aparc included in the commonly used open-source tool, Freesurfer. The work presented here provides a real-life, rapid deep learning-based brain segmentation tool to enable clinical translation as well as research application of quantitative brain segmentation. The advantages of the presented tool include short (~1 minute) processing time and improved segmentation quality. This is the first study to perform quick and accurate segmentation of 102 brain regions based on the surface-based protocol (DMK protocol), widely used by experts in the field. This is also the first work to include an expert reader study to assess the quality of the segmentation obtained using a deep-learning-based model. We show the superior performance of our deep-learning-based models over the traditional segmentation tool, Freesurfer. We refer to the proposed deep learning-based tool as DARTS (DenseUnet-based Automatic Rapid Tool for brain Segmentation). Our tool and trained models are available at https://github.com/NYUMedML/DARTS

q-bio.QM

Identification of relevant diffusion MRI metrics impacting cognitive functions using a novel feature selection method

Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to tissue microstructure using diffusion MRI. However, it remains unclear which diffusion measures are the most informative with regard to cognitive functions in both the healthy state as well as after injury. In this study, we use diffusion MRI to formulate a predictive model for performance on working memory based on the most relevant MRI features. The key challenge is to identify relevant features over a large feature space with high accuracy in an efficient manner. To tackle this challenge, we propose a novel improvement of the best first search approach with crossover operators inspired by genetic algorithm. Compared against other heuristic feature selection algorithms, the proposed method achieves significantly more accurate predictions and yields clinically interpretable selected features.

eess.IV

MTBI Identification From Diffusion MR Images Using Bag of Adversarial Visual Features

In this work, we propose bag of adversarial features (BAF) for identifying mild traumatic brain injury (MTBI) patients from their diffusion magnetic resonance images (MRI) (obtained within one month of injury) by incorporating unsupervised feature learning techniques. MTBI is a growing public health problem with an estimated incidence of over 1.7 million people annually in US. Diagnosis is based on clinical history and symptoms, and accurate, concrete measures of injury are lacking. Unlike most of previous works, which use hand-crafted features extracted from different parts of brain for MTBI classification, we employ feature learning algorithms to learn more discriminative representation for this task. A major challenge in this field thus far is the relatively small number of subjects available for training. This makes it difficult to use an end-to-end convolutional neural network to directly classify a subject from MR images. To overcome this challenge, we first apply an adversarial auto-encoder (with convolutional structure) to learn patch-level features, from overlapping image patches extracted from different brain regions. We then aggregate these features through a bag-of-word approach. We perform an extensive experimental study on a dataset of 227 subjects (including 109 MTBI patients, and 118 age and sex matched healthy controls), and compare the bag-of-deep-features with several previous approaches. Our experimental results show that the BAF significantly outperforms earlier works relying on the mean values of MR metrics in selected brain regions.

cs.CV

A Deep Unsupervised Learning Approach Toward MTBI Identification Using Diffusion MRI

Mild traumatic brain injury is a growing public health problem with an estimated incidence of over 1.7 million people annually in US. Diagnosis is based on clinical history and symptoms, and accurate, concrete measures of injury are lacking. This work aims to directly use diffusion MR images obtained within one month of trauma to detect injury, by incorporating deep learning techniques. To overcome the challenge due to limited training data, we describe each brain region using the bag of word representation, which specifies the distribution of representative patch patterns. We apply a convolutional auto-encoder to learn the patch-level features, from overlapping image patches extracted from the MR images, to learn features from diffusion MR images of brain using an unsupervised approach. Our experimental results show that the bag of word representation using patch level features learnt by the auto encoder provides similar performance as that using the raw patch patterns, both significantly outperform earlier work relying on the mean values of MR metrics in selected brain regions.

cs.CV

Low Rank plus Sparse Decomposition of ODFs for Improved Detection of Group-level Differences and Variable Correlations in White Matter

A novel approach is presented for group statistical analysis of diffusion weighted MRI datasets through voxelwise Orientation Distribution Functions (ODF). Recent advances in MRI acquisition make it possible to use high quality diffusion weighted protocols (multi-shell, large number of gradient directions) for routine in vivo study of white matter architecture. The dimensionality of these data sets is however often reduced to simplify statistical analysis. While these approaches may detect large group differences, they do not fully capitalize on all acquired image volumes. Incorporation of all available diffusion information in the analysis however risks biasing the outcome by outliers. Here we propose a statistical analysis method operating on the ODF, either the diffusion ODF or fiber ODF. To avoid outlier bias and reliably detect voxelwise group differences and correlations with demographic or behavioral variables, we apply the Low-Rank plus Sparse (L + S) matrix decomposition on the voxelwise ODFs which separates the sparse individual variability in the sparse matrix S whilst recovering the essential ODF features in the low-rank matrix L. We demonstrate the performance of this ODF L + S approach by replicating the established negative association between global white matter integrity and physical obesity in the Human Connectome dataset. The volume of positive findings agrees with and expands on the volume found by TBSS, Connectivity based fixel enhancement and Connectometry. In the same dataset we further localize the correlations of brain structure with neurocognitive measures such as fluid intelligence and episodic memory. The presented ODF L + S approach will aid in the full utilization of all acquired diffusion weightings leading to the detection of smaller group differences in clinically relevant settings as well as in neuroscience applications.

physics.med-ph

Identifying Mild Traumatic Brain Injury Patients From MR Images Using Bag of Visual Words

Mild traumatic brain injury (mTBI) is a growing public health problem with an estimated incidence of one million people annually in US. Neurocognitive tests are used to both assess the patient condition and to monitor the patient progress. This work aims to directly use MR images taken shortly after injury to detect whether a patient suffers from mTBI, by incorporating machine learning and computer vision techniques to learn features suitable discriminating between mTBI and normal patients. We focus on 3 regions in brain, and extract multiple patches from them, and use bag-of-visual-word technique to represent each subject as a histogram of representative patterns derived from patches from all training subjects. After extracting the features, we use greedy forward feature selection, to choose a subset of features which achieves highest accuracy. We show through experimental studies that BoW features perform better than the simple mean value features which were used previously.

cs.CV

A Machine Learning Approach For Identifying Patients with Mild Traumatic Brain Injury Using Diffusion MRI Modeling

While diffusion MRI has been extremely promising in the study of MTBI, identifying patients with recent MTBI remains a challenge. The literature is mixed with regard to localizing injury in these patients, however, gray matter such as the thalamus and white matter including the corpus callosum and frontal deep white matter have been repeatedly implicated as areas at high risk for injury. The purpose of this study is to develop a machine learning framework to classify MTBI patients and controls using features derived from multi-shell diffusion MRI in the thalamus, frontal white matter and corpus callosum.

cs.CV