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Xuchen Li

Publications and source records attributed to Xuchen Li.

At least 19 recordsLinked to original sources

VINCENT: Validated Interaction Network for Cross-drug Explanation of Therapeutics

Drug synergy prediction estimates whether two drugs produce a stronger joint effect than expected from their individual activities. For drug combination discovery, a single synergy score is often not enough: researchers also need to know which molecular regions jointly drive the prediction. We study motif-pair synergy explanation, which identifies pairs of chemically coherent regions, one from each drug, that jointly contribute to predicted synergy. Existing interpretable synergy models expose atom- or substructure-level signals, but their explanations are built into the predictor architecture, and none validates cross-drug region scores under repeated perturbations or feeds that evidence back to refine the explanation. A reliable motif-pair explanation should instead be chemically coherent, perturbation-stable, and aligned with predictor behavior. We introduce VINCENT (Validated Interaction Network for Cross-drug Explanation of Therapeutics), a post-training framework for a fixed interaction-aware synergy predictor. VINCENT extracts atom-pair evidence from attention and gradient signals, groups atoms into chemically coherent motifs, and validates candidate motif pairs through repeated local perturbations. The validated evidence is fed back to refine motif assignments, yielding explanations that satisfy these three criteria. On a 25-pair literature-annotated subset, VINCENT achieves a mean motif recall of 0.826 (95% CI: 0.78-0.87), compared with 0.49-0.66 for baselines. Across all 71 test pairs, its validated interaction scores yield a TP/TN separation of 3.36. These results show that closed-loop perturbation validation recovers literature-supported molecular regions more accurately than existing alternatives while producing cross-drug interaction scores that better reflect predictor behavior.

cs.LG

Scalable Generative Game Engine: Breaking the Resolution Wall via Hardware-Algorithm Co-Design

Real-time generative game engines represent a paradigm shift in interactive simulation, promising to replace traditional graphics pipelines with neural world models. However, existing approaches are fundamentally constrained by the ``Memory Wall,'' restricting practical deployments to low resolutions (e.g., $64 \times 64$). This paper bridges the gap between generative models and high-resolution neural simulations by introducing a scalable \textit{Hardware-Algorithm Co-Design} framework. We identify that high-resolution generation suffers from a critical resource mismatch: the World Model is compute-bound while the Decoder is memory-bound. To address this, we propose a heterogeneous architecture that intelligently decouples these components across a cluster of AI accelerators. Our system features three core innovations: (1) an asymmetric resource allocation strategy that optimizes throughput under sequence parallelism constraints; (2) a memory-centric operator fusion scheme that minimizes off-chip bandwidth usage; and (3) a manifold-aware latent extrapolation mechanism that exploits temporal redundancy to mask latency. We validate our approach on a cluster of programmable AI accelerators, enabling real-time generation at $720 \times 480$ resolution -- a $50\times$ increase in pixel throughput over prior baselines. Evaluated on both continuous 3D racing and discrete 2D platformer benchmarks, our system delivers fluid 26.4 FPS and 48.3 FPS respectively, with an amortized effective latency of 2.7 ms. This work demonstrates that resolving the ``Memory Wall'' via architectural co-design is not merely an optimization, but a prerequisite for enabling high-fidelity, responsive neural gameplay.

cs.AI

Beyond Accuracy: Evaluating Grounded Visual Evidence in Thinking with Images

Despite the remarkable progress of Vision-Language Models (VLMs) in adopting "Thinking-with-Images" capabilities, accurately evaluating the authenticity of their reasoning process remains a critical challenge. Existing benchmarks mainly rely on outcome-oriented accuracy, lacking the capability to assess whether models can accurately leverage fine-grained visual cues for multi-step reasoning. To address these limitations, we propose ViEBench, a process-verifiable benchmark designed to evaluate faithful visual reasoning. Comprising 200 multi-scenario high-resolution images with expert-annotated visual evidence, ViEBench uniquely categorizes tasks by difficulty into perception and reasoning dimensions, where reasoning tasks require utilizing localized visual details with prior knowledge. To establish comprehensive evaluation criteria, we introduce a dual-axis matrix that provides fine-grained metrics through four diagnostic quadrants, enabling transparent diagnosis of model behavior across varying task complexities. Our experiments yield several interesting observations: (1) VLMs can sometimes produce correct final answers despite grounding on irrelevant regions, and (2) they may successfully locate the correct evidence but still fail to utilize it to reach accurate conclusions. Our findings demonstrate that ViEBench can serve as a more explainable and practical benchmark for comprehensively evaluating the effectiveness agentic VLMs. The codes will be released at: https://github.com/Xuchen-Li/ViEBench.

cs.CV

MathMixup: Boosting LLM Mathematical Reasoning with Difficulty-Controllable Data Synthesis and Curriculum Learning

In mathematical reasoning tasks, the advancement of Large Language Models (LLMs) relies heavily on high-quality training data with clearly defined and well-graded difficulty levels. However, existing data synthesis methods often suffer from limited diversity and lack precise control over problem difficulty, making them insufficient for supporting efficient training paradigms such as curriculum learning. To address these challenges, we propose MathMixup, a novel data synthesis paradigm that systematically generates high-quality, difficulty-controllable mathematical reasoning problems through hybrid and decomposed strategies. Automated self-checking and manual screening are incorporated to ensure semantic clarity and a well-structured difficulty gradient in the synthesized data. Building on this, we construct the MathMixupQA dataset and design a curriculum learning strategy that leverages these graded problems, supporting flexible integration with other datasets. Experimental results show that MathMixup and its curriculum learning strategy significantly enhance the mathematical reasoning performance of LLMs. Fine-tuned Qwen2.5-7B achieves an average score of 52.6\% across seven mathematical benchmarks, surpassing previous state-of-the-art methods. These results fully validate the effectiveness and broad applicability of MathMixup in improving the mathematical reasoning abilities of LLMs and advancing data-centric curriculum learning.

cs.LG

STEMVerse: A Dual-Axis Diagnostic Framework for STEM Reasoning in Large Language Models

As Large Language Models (LLMs) achieve significant breakthroughs in complex reasoning tasks, evaluating their proficiency in science, technology, engineering, and mathematics (STEM) has become a primary method for measuring machine intelligence. However, current evaluation paradigms often treat benchmarks as isolated "silos," offering only monolithic aggregate scores that neglect the intricacies of both academic specialization and cognitive depth. This result-oriented approach fails to distinguish whether model errors stem from insufficient domain knowledge or deficiencies in cognitive capacity, thereby limiting the diagnostic value. To address this, we propose STEMVerse, a diagnostic framework designed to systematically analyze the STEM reasoning capabilities of LLMs. This framework characterizes model performance across academic specialization and cognitive complexity to map the capability required for reasoning. We re-aggregate over 20,000 STEM problems from mainstream benchmarks into a unified "Discipline $\times$ Cognition" capability space, assigning dual-axis labels to every instance. Utilizing this unified diagnostic framework, we systematically evaluate representative LLM families across varying parameter scales and training paradigms. Our empirical results reveal structural failure patterns in STEM reasoning. By integrating multi-disciplinary coverage and fine-grained cognitive stratification into a unified framework, STEMVerse provides a clear and actionable perspective for understanding the scientific reasoning characteristics of LLMs.

cs.CL

PPBoost: Progressive Prompt Boosting for Text-Driven Medical Image Segmentation

Text-prompted foundation models for medical image segmentation offer an intuitive way to delineate anatomical structures from natural language queries, but their predictions often lack spatial precision and degrade under domain shift. In contrast, visual-prompted models achieve strong segmentation performance across diverse modalities by leveraging spatial cues of precise bounding-box (bbox) prompts to guide the segmentation of target lesions. However, it is costly and challenging to obtain the precise visual prompts in clinical practice. We propose PPBoost (Progressive Prompt-Boosting), a framework that bridges these limitations by transforming weak text-derived signals into strong, spatially grounded visual prompts, operating under a strict zero-shot regime with no image- or pixel-level segmentation labels. PPBoost first uses a vision-language model to produce initial pseudo-bboxes conditioned on the textual object descriptions and applies an uncertainty-aware criterion to filter unreliable predictions. The retained image-bboxes pairs are then leveraged to train a pseudo-labeled detector, producing the high-quality bboxes for the query images. During inference, PPBoost further refines the generated bboxes by appropriately expanding them to tightly cover the target anatomical structures. The enhanced spatially-grounding bbox prompts guide existing segmentation models to generate final dense masks, effectively amplifying weak text cues into strong spatial guidance. Across three datasets spanning diverse modalities and anatomies, PPBoost consistently improves Dice and Normalized Surface Distance over text- and visual-prompted baselines and, notably, surpasses few-shot segmentation models without using labeled data. PPBoost can generalize to multiple typical visual segmentation model backbones.

cs.CV

SciAgent: A Unified Multi-Agent System for Generalistic Scientific Reasoning

Recent advances in large language models have enabled AI systems to achieve expert-level performance on domain-specific scientific tasks, yet these systems remain narrow and handcrafted. We introduce SciAgent, a unified multi-agent system designed for generalistic scientific reasoning-the ability to adapt reasoning strategies across disciplines and difficulty levels. SciAgent organizes problem solving as a hierarchical process: a Coordinator Agent interprets each problem's domain and complexity, dynamically orchestrating specialized Worker Systems, each composed of interacting reasoning Sub-agents for symbolic deduction, conceptual modeling, numerical computation, and verification. These agents collaboratively assemble and refine reasoning pipelines tailored to each task. Across mathematics and physics Olympiads (IMO, IMC, IPhO, CPhO), SciAgent consistently attains or surpasses human gold-medalist performance, demonstrating both domain generality and reasoning adaptability. Additionally, SciAgent has been tested on the International Chemistry Olympiad (IChO) and selected problems from the Humanity's Last Exam (HLE) benchmark, further confirming the system's ability to generalize across diverse scientific domains. This work establishes SciAgent as a concrete step toward generalistic scientific intelligence-AI systems capable of coherent, cross-disciplinary reasoning at expert levels.

cs.AI

MATrack: Efficient Multiscale Adaptive Tracker for Real-Time Nighttime UAV Operations

Nighttime UAV tracking faces significant challenges in real-world robotics operations. Low-light conditions not only limit visual perception capabilities, but cluttered backgrounds and frequent viewpoint changes also cause existing trackers to drift or fail during deployment. To address these difficulties, researchers have proposed solutions based on low-light enhancement and domain adaptation. However, these methods still have notable shortcomings in actual UAV systems: low-light enhancement often introduces visual artifacts, domain adaptation methods are computationally expensive and existing lightweight designs struggle to fully leverage dynamic object information. Based on an in-depth analysis of these key issues, we propose MATrack-a multiscale adaptive system designed specifically for nighttime UAV tracking. MATrack tackles the main technical challenges of nighttime tracking through the collaborative work of three core modules: Multiscale Hierarchy Blende (MHB) enhances feature consistency between static and dynamic templates. Adaptive Key Token Gate accurately identifies object information within complex backgrounds. Nighttime Template Calibrator (NTC) ensures stable tracking performance over long sequences. Extensive experiments show that MATrack achieves a significant performance improvement. On the UAVDark135 benchmark, its precision, normalized precision and AUC surpass state-of-the-art (SOTA) methods by 5.9%, 5.4% and 4.2% respectively, while maintaining a real-time processing speed of 81 FPS. Further tests on a real-world UAV platform validate the system's reliability, demonstrating that MATrack can provide stable and effective nighttime UAV tracking support for critical robotics applications such as nighttime search and rescue and border patrol.

cs.CV

Select Less, Reason More: Prioritizing Evidence Purity for Video Reasoning

Long-form video reasoning remains a major challenge for Video Large Language Models (Video LLMs), as static uniform frame sampling leads to information dilution and obscures critical evidence. Furthermore, existing pixel-space video reasoning agents, which are designed to actively interact with the video to acquire new visual information, remain suboptimal due to their lack of rigorous reward mechanisms to enforce evidence purity and their inability to perform temporal information supplementation beyond pre-sampled frames. To address this critical gap, we propose a novel evidence-prioritized adaptive framework built upon our core philosophy: "Select Less, Reason More." Our core contribution is the evidence-aware reinforcement learning (EARL) framework, which transforms the model into an active interrogator of evidence. EARL is precisely engineered to dynamically select the most relevant frames and, crucially, to perform localized re-sampling around the selected key frames to access fine-grained temporal detail. Extensive experiments on five demanding video reasoning benchmarks demonstrate that our EARL-trained model achieves new state-of-the-art among open-source Video LLMs, simultaneously learning an effective and high-purity visual evidence selection policy. Impressively, our 7B model achieves 59.8% on LongVideoBench, 69.0% on MVBench and 64.9% on VideoMME. These results highlight the importance of prioritizing evidence purity and the effectiveness of our framework.

cs.CV

MorphoBench: A Benchmark with Difficulty Adaptive to Model Reasoning

With the advancement of powerful large-scale reasoning models, effectively evaluating the reasoning capabilities of these models has become increasingly important. However, existing benchmarks designed to assess the reasoning abilities of large models tend to be limited in scope and lack the flexibility to adapt their difficulty according to the evolving reasoning capacities of the models. To address this, we propose MorphoBench, a benchmark that incorporates multidisciplinary questions to evaluate the reasoning capabilities of large models and can adjust and update question difficulty based on the reasoning abilities of advanced models. Specifically, we curate the benchmark by selecting and collecting complex reasoning questions from existing benchmarks and sources such as Olympiad-level competitions. Additionally, MorphoBench adaptively modifies the analytical challenge of questions by leveraging key statements generated during the model's reasoning process. Furthermore, it includes questions generated using simulation software, enabling dynamic adjustment of benchmark difficulty with minimal resource consumption. We have gathered over 1,300 test questions and iteratively adjusted the difficulty of MorphoBench based on the reasoning capabilities of models such as o3 and GPT-5. MorphoBench enhances the comprehensiveness and validity of model reasoning evaluation, providing reliable guidance for improving both the reasoning abilities and scientific robustness of large models. The code has been released in https://github.com/OpenDCAI/MorphoBench.

cs.AI

Look Less, Reason More: Rollout-Guided Adaptive Pixel-Space Reasoning

Vision-Language Models (VLMs) excel at many multimodal tasks, yet they frequently struggle with tasks requiring precise understanding and handling of fine-grained visual elements. This is mainly due to information loss during image encoding or insufficient attention to critical regions. Recent work has shown promise by incorporating pixel-level visual information into the reasoning process, enabling VLMs to access high-resolution visual details during their thought process. However, this pixel-level information is often overused, leading to inefficiency and distraction from irrelevant visual details. To address these challenges, we propose the first framework for adaptive pixel reasoning that dynamically determines necessary pixel-level operations based on the input query. Specifically, we first apply operation-aware supervised fine-tuning to establish baseline competence in textual reasoning and visual operations, then design a novel rollout-guided reinforcement learning framework relying on feedback of the model's own responses, which enables the VLM to determine when pixel operations should be invoked based on query difficulty. Experiments on extensive multimodal reasoning benchmarks show that our model achieves superior performance while significantly reducing unnecessary visual operations. Impressively, our model achieves 73.4\% accuracy on HR-Bench 4K while maintaining a tool usage ratio of only 20.1\%, improving accuracy and simultaneously reducing tool usage by 66.5\% compared to the previous methods.

cs.CV

VS-LLM: Visual-Semantic Depression Assessment based on LLM for Drawing Projection Test

The Drawing Projection Test (DPT) is an essential tool in art therapy, allowing psychologists to assess participants' mental states through their sketches. Specifically, through sketches with the theme of "a person picking an apple from a tree (PPAT)", it can be revealed whether the participants are in mental states such as depression. Compared with scales, the DPT can enrich psychologists' understanding of an individual's mental state. However, the interpretation of the PPAT is laborious and depends on the experience of the psychologists. To address this issue, we propose an effective identification method to support psychologists in conducting a large-scale automatic DPT. Unlike traditional sketch recognition, DPT more focus on the overall evaluation of the sketches, such as color usage and space utilization. Moreover, PPAT imposes a time limit and prohibits verbal reminders, resulting in low drawing accuracy and a lack of detailed depiction. To address these challenges, we propose the following efforts: (1) Providing an experimental environment for automated analysis of PPAT sketches for depression assessment; (2) Offering a Visual-Semantic depression assessment based on LLM (VS-LLM) method; (3) Experimental results demonstrate that our method improves by 17.6% compared to the psychologist assessment method. We anticipate that this work will contribute to the research in mental state assessment based on PPAT sketches' elements recognition. Our datasets and codes are available at https://github.com/wmeiqi/VS-LLM.

cs.CV

CausalStep: A Benchmark for Explicit Stepwise Causal Reasoning in Videos

Recent advances in large language models (LLMs) have improved reasoning in text and image domains, yet achieving robust video reasoning remains a significant challenge. Existing video benchmarks mainly assess shallow understanding and reasoning and allow models to exploit global context, failing to rigorously evaluate true causal and stepwise reasoning. We present CausalStep, a benchmark designed for explicit stepwise causal reasoning in videos. CausalStep segments videos into causally linked units and enforces a strict stepwise question-answer (QA) protocol, requiring sequential answers and preventing shortcut solutions. Each question includes carefully constructed distractors based on error type taxonomy to ensure diagnostic value. The benchmark features 100 videos across six categories and 1,852 multiple-choice QA pairs. We introduce seven diagnostic metrics for comprehensive evaluation, enabling precise diagnosis of causal reasoning capabilities. Experiments with leading proprietary and open-source models, as well as human baselines, reveal a significant gap between current models and human-level stepwise reasoning. CausalStep provides a rigorous benchmark to drive progress in robust and interpretable video reasoning.

cs.CV

VerifyBench: A Systematic Benchmark for Evaluating Reasoning Verifiers Across Domains

Large language models (LLMs) increasingly rely on reinforcement learning (RL) to enhance their reasoning capabilities through feedback. A critical challenge is verifying the consistency of model-generated responses and reference answers, since these responses are often lengthy, diverse, and nuanced. Rule-based verifiers struggle with complexity, prompting the use of model-based verifiers. However, specialized verifiers lack flexibility, while general LLM judges can be inconsistent. Existing research primarily focuses on building better verifiers, yet a systematic evaluation of different types of verifiers' performance across domains remains lacking, severely constraining the reliable development of Reinforcement Learning with Verifiable Reward (RLVR). To address this, we propose VerifyBench--a cross-domain comprehensive benchmark for systematically evaluating verifiers. We construct 4,000 expert-level questions covering mathematics, physics, chemistry, and biology. Each question is equipped with reference answers and diverse responses. The reliability of the evaluation is ensured through a rigorous annotation process conducted by a multidisciplinary expert team. We design a four-dimensional experimental framework to comprehensively compare the performance boundaries of specialized verifiers and general LLMs under combined conditions of extracted answers vs. complete responses, and short vs. long outputs. Our evaluation uncovers fundamental trade-offs in verifiers: while specialized verifiers achieve leading accuracy, they exhibit deficiencies in recall; general models show stronger inclusivity but unstable precision. More importantly, we discover verifiers' high sensitivity to input structure and inherent limitations in cross-domain generalization, providing critical insights into the bottlenecks of current verifier technology.

cs.AI

DARTer: Dynamic Adaptive Representation Tracker for Nighttime UAV Tracking

Nighttime UAV tracking presents significant challenges due to extreme illumination variations and viewpoint changes, which severely degrade tracking performance. Existing approaches either rely on light enhancers with high computational costs or introduce redundant domain adaptation mechanisms, failing to fully utilize the dynamic features in varying perspectives. To address these issues, we propose \textbf{DARTer} (\textbf{D}ynamic \textbf{A}daptive \textbf{R}epresentation \textbf{T}racker), an end-to-end tracking framework designed for nighttime UAV scenarios. DARTer leverages a Dynamic Feature Blender (DFB) to effectively fuse multi-perspective nighttime features from static and dynamic templates, enhancing representation robustness. Meanwhile, a Dynamic Feature Activator (DFA) adaptively activates Vision Transformer layers based on extracted features, significantly improving efficiency by reducing redundant computations. Our model eliminates the need for complex multi-task loss functions, enabling a streamlined training process. Extensive experiments on multiple nighttime UAV tracking benchmarks demonstrate the superiority of DARTer over state-of-the-art trackers. These results confirm that DARTer effectively balances tracking accuracy and efficiency, making it a promising solution for real-world nighttime UAV tracking applications.

cs.CV

How Texts Help? A Fine-grained Evaluation to Reveal the Role of Language in Vision-Language Tracking

Vision-language tracking (VLT) extends traditional single object tracking by incorporating textual information, providing semantic guidance to enhance tracking performance under challenging conditions like fast motion and deformations. However, current VLT trackers often underperform compared to single-modality methods on multiple benchmarks, with semantic information sometimes becoming a "distraction." To address this, we propose VLTVerse, the first fine-grained evaluation framework for VLT trackers that comprehensively considers multiple challenge factors and diverse semantic information, hoping to reveal the role of language in VLT. Our contributions include: (1) VLTVerse introduces 10 sequence-level challenge labels and 6 types of multi-granularity semantic information, creating a flexible and multi-dimensional evaluation space for VLT; (2) leveraging 60 subspaces formed by combinations of challenge factors and semantic types, we conduct systematic fine-grained evaluations of three mainstream SOTA VLT trackers, uncovering their performance bottlenecks across complex scenarios and offering a novel perspective on VLT evaluation; (3) through decoupled analysis of experimental results, we examine the impact of various semantic types on specific challenge factors in relation to different algorithms, providing essential guidance for enhancing VLT across data, evaluation, and algorithmic dimensions. The VLTVerse, toolkit, and results will be available at \url{http://metaverse.aitestunion.com}.

cs.CV

When LLMs Learn to be Students: The SOEI Framework for Modeling and Evaluating Virtual Student Agents in Educational Interaction

Recent advances in large language models (LLMs) have enabled intelligent tutoring systems, yet the development of LLM-based Virtual Student Agents (LVSAs) remains underexplored. Such agents are essential for teacher-facing applications, where simulating diverse learner traits can support adaptive instruction and pedagogical skill development. However, current methods lack principled personality modeling, scalable evaluation of behavioral consistency, and empirical validation in interactive teaching settings. We propose the SOEI framework, a structured pipeline comprising Scene, Object, Evaluation, and Interaction, for constructing and evaluating personality-aligned LVSAs in classroom scenarios. Leveraging Chinese language instruction as a cognitively and emotionally rich testbed, we generate five LVSAs based on Big Five traits through LoRA fine-tuning and expert-informed prompt design. Their behavioral realism and personality coherence are assessed using a hybrid human & GPT-4 evaluation and a multi-dimensional annotation protocol. Through controlled experiments with real pre-service teachers, we demonstrate that LVSAs can elicit adaptive teaching strategies and maintain trait-consistent behavior across multi-turn dialogues. Our results provide: (1) an educationally and psychologically grounded generation pipeline for LLM-based student agents; (2) a hybrid, scalable evaluation framework for behavioral realism; and (3) empirical insights into the pedagogical utility of LVSAs in shaping instructional adaptation. By embedding LVSAs into both generative modeling and human-in-the-loop teaching, SOEI bridges AI for Education (AI4Edu) and Education for AI (Edu4AI), positioning classroom interaction as a rigorous testbed for controllability, personality alignment, and human-likeness in large language models.

cs.CV

FIOVA: A Multi-Annotator Benchmark for Human-Aligned Video Captioning

Despite rapid progress in large vision-language models (LVLMs), existing video caption benchmarks remain limited in evaluating their alignment with human understanding. Most rely on a single annotation per video and lexical similarity-based metrics, failing to capture the variability in human perception and the cognitive importance of events. These limitations hinder accurate diagnosis of model capabilities in producing coherent, complete, and human-aligned descriptions. To address this, we introduce FIOVA (Five-In-One Video Annotations), a human-centric benchmark tailored for evaluation. It comprises 3,002 real-world videos (about 33.6s each), each annotated independently by five annotators. This design enables modeling of semantic diversity and inter-subjective agreement, offering a richer foundation for measuring human-machine alignment. We further propose FIOVA-DQ, an event-level evaluation metric that incorporates cognitive weights derived from annotator consensus, providing fine-grained assessment of event relevance and semantic coverage. Leveraging FIOVA, we conduct a comprehensive evaluation of nine representative LVLMs and introduce a complexity-aware analysis framework based on inter-annotator variation (CV). This reveals consistency gaps across difficulty levels and identifies structural issues such as event under-description and template convergence. Our results highlight FIOVA's diagnostic value for understanding LVLM behavior under varying complexity, setting a new standard for cognitively aligned evaluation in long-video captioning. The benchmark, annotations, metric, and model outputs are publicly released to support future evaluation-driven research in video understanding. More detailed information can be found at https://huuuuusy.github.io/fiova/.

cs.CV