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Xuefei

Publications and source records attributed to Xuefei.

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Developing the PsyCogMetrics AI Lab to Evaluate Large Language Models and Advance Cognitive Science -- A Three-Cycle Action Design Science Study

This study presents the development of the PsyCogMetrics AI Lab (psycogmetrics.ai), an integrated, cloud-based platform that operationalizes psychometric and cognitive-science methodologies for Large Language Model (LLM) evaluation. Framed as a three-cycle Action Design Science study, the Relevance Cycle identifies key limitations in current evaluation methods and unfulfilled stakeholder needs. The Rigor Cycle draws on kernel theories such as Popperian falsifiability, Classical Test Theory, and Cognitive Load Theory to derive deductive design objectives. The Design Cycle operationalizes these objectives through nested Build-Intervene-Evaluate loops. The study contributes a novel IT artifact, a validated design for LLM evaluation, benefiting research at the intersection of AI, psychology, cognitive science, and the social and behavioral sciences.

q-bio.NC

Counterweights and Complementarities: The Convergence of AI and Blockchain Powering a Decentralized Future

This editorial addresses the critical intersection of artificial intelligence (AI) and blockchain technologies, highlighting their contrasting tendencies toward centralization and decentralization, respectively. While AI, particularly with the rise of large language models (LLMs), exhibits a strong centralizing force due to data and resource monopolization by large corporations, blockchain offers a counterbalancing mechanism through its inherent decentralization, transparency, and security. The editorial argues that these technologies are not mutually exclusive but possess complementary strengths. Blockchain can mitigate AI's centralizing risks by enabling decentralized data management, computation, and governance, promoting greater inclusivity, transparency, and user privacy. Conversely, AI can enhance blockchain's efficiency and security through automated smart contract management, content curation, and threat detection. The core argument calls for the development of ``decentralized intelligence'' (DI) -- an interdisciplinary research area focused on creating intelligent systems that function without centralized control.

cs.AI

Simple Agents Outperform Experts in Biomedical Imaging Workflow Optimization

Adapting production-level computer vision tools to bespoke scientific datasets is a critical "last mile" bottleneck. Current solutions are impractical: fine-tuning requires large annotated datasets scientists often lack, while manual code adaptation costs scientists weeks to months of effort. We consider using AI agents to automate this manual coding, and focus on the open question of optimal agent design for this targeted task. We introduce a systematic evaluation framework for agentic code optimization and use it to study three production-level biomedical imaging pipelines. We demonstrate that a simple agent framework consistently generates adaptation code that outperforms human-expert solutions. Our analysis reveals that common, complex agent architectures are not universally beneficial, leading to a practical roadmap for agent design. We open source our framework and validate our approach by deploying agent-generated functions into a production pipeline, demonstrating a clear pathway for real-world impact.

cs.CV

An AI system to help scientists write expert-level empirical software

The cycle of scientific discovery is frequently bottlenecked by the slow, manual creation of software to support computational experiments\cite{hannay2009how}. To address this, we present Empirical Research Assistance (ERA), an AI system that creates expert-level scientific software whose goal is to maximize a quality metric. The system uses a Large Language Model (LLM) and Tree Search (TS)\cite{silver2016mastering} to systematically improve the quality metric and intelligently navigate the large space of possible solutions. ERA achieves expert-level results when it explores and integrates complex research ideas from external sources. The effectiveness of tree search is demonstrated across a diverse range of tasks. In bioinformatics, ERA discovered 40 novel methods for single-cell data analysis that outperformed the top human-developed methods on a public leaderboard. In epidemiology, ERA generated 14 models that outperformed the CDC ensemble and all other individual models for forecasting COVID-19 hospitalizations. ERA also produced expert-level software for geospatial analysis, neural activity prediction in zebrafish, and numerical solution of integrals, and a novel rule-based construction for time series forecasting. By devising and implementing novel solutions to diverse tasks, ERA represents a significant step towards accelerating scientific progress.

cs.AI