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Xuming He

Publications and source records attributed to Xuming He.

142 records · Page 8Linked to original sources

Globally adaptive quantile regression with ultra-high dimensional data

Quantile regression has become a valuable tool to analyze heterogeneous covaraite-response associations that are often encountered in practice. The development of quantile regression methodology for high-dimensional covariates primarily focuses on examination of model sparsity at a single or multiple quantile levels, which are typically pre-specified ad hoc by the users. The resulting models may be sensitive to the specific choices of the quantile levels, leading to difficulties in interpretation and erosion of confidence in the results. In this article, we propose a new penalization framework for quantile regression in the high-dimensional setting. We employ adaptive L1 penalties, and more importantly, propose a uniform selector of the tuning parameter for a set of quantile levels to avoid some of the potential problems with model selection at individual quantile levels. Our proposed approach achieves consistent shrinkage of regression quantile estimates across a continuous range of quantiles levels, enhancing the flexibility and robustness of the existing penalized quantile regression methods. Our theoretical results include the oracle rate of uniform convergence and weak convergence of the parameter estimators. We also use numerical studies to confirm our theoretical findings and illustrate the practical utility of our proposal

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Bayesian quantile regression with approximate likelihood

Quantile regression is often used when a comprehensive relationship between a response variable and one or more explanatory variables is desired. The traditional frequentists' approach to quantile regression has been well developed around asymptotic theories and efficient algorithms. However, not much work has been published under the Bayesian framework. One challenging problem for Bayesian quantile regression is that the full likelihood has no parametric forms. In this paper, we propose a Bayesian quantile regression method, the linearly interpolated density (LID) method, which uses a linear interpolation of the quantiles to approximate the likelihood. Unlike most of the existing methods that aim at tackling one quantile at a time, our proposed method estimates the joint posterior distribution of multiple quantiles, leading to higher global efficiency for all quantiles of interest. Markov chain Monte Carlo algorithms are developed to carry out the proposed method. We provide convergence results that justify both the algorithmic convergence and statistical approximations to an integrated-likelihood-based posterior. From the simulation results, we verify that LID has a clear advantage over other existing methods in estimating quantities that relate to two or more quantiles.

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Bayesian variable selection with shrinking and diffusing priors

We consider a Bayesian approach to variable selection in the presence of high dimensional covariates based on a hierarchical model that places prior distributions on the regression coefficients as well as on the model space. We adopt the well-known spike and slab Gaussian priors with a distinct feature, that is, the prior variances depend on the sample size through which appropriate shrinkage can be achieved. We show the strong selection consistency of the proposed method in the sense that the posterior probability of the true model converges to one even when the number of covariates grows nearly exponentially with the sample size. This is arguably the strongest selection consistency result that has been available in the Bayesian variable selection literature; yet the proposed method can be carried out through posterior sampling with a simple Gibbs sampler. Furthermore, we argue that the proposed method is asymptotically similar to model selection with the $L_0$ penalty. We also demonstrate through empirical work the fine performance of the proposed approach relative to some state of the art alternatives.

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Statistical inference based on robust low-rank data matrix approximation

The singular value decomposition is widely used to approximate data matrices with lower rank matrices. Feng and He [Ann. Appl. Stat. 3 (2009) 1634-1654] developed tests on dimensionality of the mean structure of a data matrix based on the singular value decomposition. However, the first singular values and vectors can be driven by a small number of outlying measurements. In this paper, we consider a robust alternative that moderates the effect of outliers in low-rank approximations. Under the assumption of random row effects, we provide the asymptotic representations of the robust low-rank approximation. These representations may be used in testing the adequacy of a low-rank approximation. We use oligonucleotide gene microarray data to demonstrate how robust singular value decomposition compares with the its traditional counterparts. Examples show that the robust methods often lead to a more meaningful assessment of the dimensionality of gene intensity data matrices.

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Quantile-adaptive model-free variable screening for high-dimensional heterogeneous data

We introduce a quantile-adaptive framework for nonlinear variable screening with high-dimensional heterogeneous data. This framework has two distinctive features: (1) it allows the set of active variables to vary across quantiles, thus making it more flexible to accommodate heterogeneity; (2) it is model-free and avoids the difficult task of specifying the form of a statistical model in a high dimensional space. Our nonlinear independence screening procedure employs spline approximations to model the marginal effects at a quantile level of interest. Under appropriate conditions on the quantile functions without requiring the existence of any moments, the new procedure is shown to enjoy the sure screening property in ultra-high dimensions. Furthermore, the quantile-adaptive framework can naturally handle censored data arising in survival analysis. We prove that the sure screening property remains valid when the response variable is subject to random right censoring. Numerical studies confirm the fine performance of the proposed method for various semiparametric models and its effectiveness to extract quantile-specific information from heteroscedastic data.

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Tracking Large-Scale Video Remix in Real-World Events

Social information networks, such as YouTube, contains traces of both explicit online interaction (such as "like", leaving a comment, or subscribing to video feed), and latent interactions (such as quoting, or remixing parts of a video). We propose visual memes, or frequently re-posted short video segments, for tracking such latent video interactions at scale. Visual memes are extracted by scalable detection algorithms that we develop, with high accuracy. We further augment visual memes with text, via a statistical model of latent topics. We model content interactions on YouTube with visual memes, defining several measures of influence and building predictive models for meme popularity. Experiments are carried out on with over 2 million video shots from more than 40,000 videos on two prominent news events in 2009: the election in Iran and the swine flu epidemic. In these two events, a high percentage of videos contain remixed content, and it is apparent that traditional news media and citizen journalists have different roles in disseminating remixed content. We perform two quantitative evaluations for annotating visual memes and predicting their popularity. The joint statistical model of visual memes and words outperform a concurrence model, and the average error is ~2% for predicting meme volume and ~17% for their lifespan.

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Bayesian empirical likelihood for quantile regression

Bayesian inference provides a flexible way of combining data with prior information. However, quantile regression is not equipped with a parametric likelihood, and therefore, Bayesian inference for quantile regression demands careful investigation. This paper considers the Bayesian empirical likelihood approach to quantile regression. Taking the empirical likelihood into a Bayesian framework, we show that the resultant posterior from any fixed prior is asymptotically normal; its mean shrinks toward the true parameter values, and its variance approaches that of the maximum empirical likelihood estimator. A more interesting case can be made for the Bayesian empirical likelihood when informative priors are used to explore commonality across quantiles. Regression quantiles that are computed separately at each percentile level tend to be highly variable in the data sparse areas (e.g., high or low percentile levels). Through empirical likelihood, the proposed method enables us to explore various forms of commonality across quantiles for efficiency gains. By using an MCMC algorithm in the computation, we avoid the daunting task of directly maximizing empirical likelihood. The finite sample performance of the proposed method is investigated empirically, where substantial efficiency gains are demonstrated with informative priors on common features across several percentile levels. A theoretical framework of shrinking priors is used in the paper to better understand the power of the proposed method.

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Detection of treatment effects by covariate-adjusted expected shortfall

The statistical tests that are commonly used for detecting mean or median treatment effects suffer from low power when the two distribution functions differ only in the upper (or lower) tail, as in the assessment of the Total Sharp Score (TSS) under different treatments for rheumatoid arthritis. In this article, we propose a more powerful test that detects treatment effects through the expected shortfalls. We show how the expected shortfall can be adjusted for covariates, and demonstrate that the proposed test can achieve a substantial sample size reduction over the conventional tests on the mean effects.

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Inference on low-rank data matrices with applications to microarray data

Probe-level microarray data are usually stored in matrices, where the row and column correspond to array and probe, respectively. Scientists routinely summarize each array by a single index as the expression level of each probe set (gene). We examine the adequacy of a unidimensional summary for characterizing the data matrix of each probe set. To do so, we propose a low-rank matrix model for the probe-level intensities, and develop a useful framework for testing the adequacy of unidimensionality against targeted alternatives. This is an interesting statistical problem where inference has to be made based on one data matrix whose entries are not i.i.d. We analyze the asymptotic properties of the proposed test statistics, and use Monte Carlo simulations to assess their small sample performance. Applications of the proposed tests to GeneChip data show that evidence against a unidimensional model is often indicative of practically relevant features of a probe set.

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Efficient randomized-adaptive designs

Response-adaptive randomization has recently attracted a lot of attention in the literature. In this paper, we propose a new and simple family of response-adaptive randomization procedures that attain the Cramer--Rao lower bounds on the allocation variances for any allocation proportions, including optimal allocation proportions. The allocation probability functions of proposed procedures are discontinuous. The existing large sample theory for adaptive designs relies on Taylor expansions of the allocation probability functions, which do not apply to nondifferentiable cases. In the present paper, we study stopping times of stochastic processes to establish the asymptotic efficiency results. Furthermore, we demonstrate our proposal through examples, simulations and a discussion on the relationship with earlier works, including Efron's biased coin design.

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Dimension reduction based on constrained canonical correlation and variable filtering

The ``curse of dimensionality'' has remained a challenge for high-dimensional data analysis in statistics. The sliced inverse regression (SIR) and canonical correlation (CANCOR) methods aim to reduce the dimensionality of data by replacing the explanatory variables with a small number of composite directions without losing much information. However, the estimated composite directions generally involve all of the variables, making their interpretation difficult. To simplify the direction estimates, Ni, Cook and Tsai [Biometrika 92 (2005) 242--247] proposed the shrinkage sliced inverse regression (SSIR) based on SIR. In this paper, we propose the constrained canonical correlation ($C^3$) method based on CANCOR, followed by a simple variable filtering method. As a result, each composite direction consists of a subset of the variables for interpretability as well as predictive power. The proposed method aims to identify simple structures without sacrificing the desirable properties of the unconstrained CANCOR estimates. The simulation studies demonstrate the performance advantage of the proposed $C^3$ method over the SSIR method. We also use the proposed method in two examples for illustration.

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Robust estimates in generalized partially linear models

In this paper, we introduce a family of robust estimates for the parametric and nonparametric components under a generalized partially linear model, where the data are modeled by $y_i|(\mathbf{x}_i,t_i)\sim F(\cdot,μ_i)$ with $μ_i=H(η(t_i)+\mathbf{x}_i^{$\mathrm{T}$}β)$, for some known distribution function F and link function H. It is shown that the estimates of $β$ are root-n consistent and asymptotically normal. Through a Monte Carlo study, the performance of these estimators is compared with that of the classical ones.

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On the limiting distributions of multivariate depth-based rank sum statistics and related tests

A depth-based rank sum statistic for multivariate data introduced by Liu and Singh [J. Amer. Statist. Assoc. 88 (1993) 252--260] as an extension of the Wilcoxon rank sum statistic for univariate data has been used in multivariate rank tests in quality control and in experimental studies. Those applications, however, are based on a conjectured limiting distribution, provided by Liu and Singh [J. Amer. Statist. Assoc. 88 (1993) 252--260]. The present paper proves the conjecture under general regularity conditions and, therefore, validates various applications of the rank sum statistic in the literature. The paper also shows that the corresponding rank sum tests can be more powerful than Hotelling's T^2 test and some commonly used multivariate rank tests in detecting location-scale changes in multivariate distributions.

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Discussion paper. Conditional growth charts

Growth charts are often more informative when they are customized per subject, taking into account prior measurements and possibly other covariates of the subject. We study a global semiparametric quantile regression model that has the ability to estimate conditional quantiles without the usual distributional assumptions. The model can be estimated from longitudinal reference data with irregular measurement times and with some level of robustness against outliers, and it is also flexible for including covariate information. We propose a rank score test for large sample inference on covariates, and develop a new model assessment tool for longitudinal growth data. Our research indicates that the global model has the potential to be a very useful tool in conditional growth chart analysis.

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Breakdown and groups

The concept of breakdown point was introduced by Hampel [Ph.D. dissertation (1968), Univ. California, Berkeley; Ann. Math. Statist. 42 (1971) 1887-1896] and developed further by, among others, Huber [Robust Statistics (1981). Wiley, New York] and Donoho and Huber [In A Festschrift for Erich L. Lehmann (1983) 157-184. Wadsworth, Belmont, CA]. It has proved most successful in the context of location, scale and regression problems. Attempts to extend the concept to other situations have not met with general acceptance. In this paper we argue that this is connected to the fact that in the location, scale and regression problems the translation and affine groups give rise to a definition of equivariance for statistical functionals. Comparisons in terms of breakdown points seem only useful when restricted to equivariant functionals and even here the connection between breakdown and equivariance is a tenuous one.

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