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Y. Samuel Wang

Publications and source records attributed to Y. Samuel Wang.

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Nonparametric Regression via Tree-Guided Feature Aggregation

In regression problems where covariates are naturally organized in a hierarchical tree structure, a central challenge is to select the resolution at which covariates enter the model. Determining this level of feature aggregation is of intrinsic scientific interest and can improve statistical efficiency by inducing sparsity. While a rich literature addresses this problem in the linear setting, extending feature aggregation to the nonlinear setting remains an open challenge. In this work, we propose to simultaneously perform model selection and feature aggregation through a penalized Nadaraya-Watson-type estimator. Our proposed estimator, Kernel Regression with Tree-EXploring AggregationS (KR-TEXAS), constructs adaptive penalty weights for the features based on pilot estimators of the regression function's partial derivatives. Under mild conditions, we establish model selection consistency for a well-defined target aggregation set, and our simulations show strong performance in both model selection and prediction. Finally, we demonstrate the utility of our procedure by applying it to a microbiome data set to predict short chain fatty acids. A user-friendly implementation of our procedure is available in the R package krtexas.

stat.ME

Causal Discovery for Linear Non-Gaussian Models with Disjoint Cycles

The paradigm of linear structural equation modeling readily allows one to incorporate causal feedback loops in the model specification. These appear as directed cycles in the common graphical representation of the models. However, the presence of cycles entails difficulties such as the fact that models need no longer be characterized by conditional independence relations. As a result, learning cyclic causal structures remains a challenging problem. In this paper, we offer new insights on this problem in the context of linear non-Gaussian models. First, we precisely characterize when two directed graphs determine the same linear non-Gaussian model. Next, we take up a setting of cycle-disjoint graphs, for which we are able to show that simple quadratic and cubic polynomial relations among low-order moments of a non-Gaussian distribution allow one to locate source cycles. Complementing this with a strategy of decorrelating cycles and multivariate regression allows one to infer a block-topological order among the directed cycles, which leads to a {consistent and computationally efficient algorithm} for learning causal structures with disjoint cycles.

math.ST

Bayesian analysis of regression discontinuity designs with heterogeneous treatment effects

Regression Discontinuity Design (RDD) is a popular framework for estimating a causal effect in settings where treatment is assigned if an observed covariate exceeds a fixed threshold. We consider estimation and inference in the common setting where the sample consists of multiple known sub-populations with potentially heterogeneous treatment effects. In the applied literature, it is common to account for heterogeneity by either fitting a parametric model or considering each sub-population separately. In contrast, we develop a Bayesian hierarchical model using Gaussian process regression which allows for non-parametric regression while borrowing information across sub-populations. We derive the posterior distribution, prove posterior consistency, and develop a Metropolis-Hastings within Gibbs sampling algorithm. In extensive simulations, we show that the proposed procedure outperforms existing methods in both estimation and inferential tasks. Finally, we apply our procedure to U.S. Senate election data and discover an incumbent party advantage which is heterogeneous over different time periods.

math.ST

Confidence Sets for Causal Orderings

Causal discovery procedures aim to deduce causal relationships among variables in a multivariate dataset. While various methods have been proposed for estimating a single causal model or a single equivalence class of models, less attention has been given to quantifying uncertainty in causal discovery in terms of confidence statements. A primary challenge in causal discovery of directed acyclic graphs is determining a causal ordering among the variables, and our work offers a framework for constructing confidence sets of causal orderings that the data do not rule out. Our methodology specifically applies to identifiable structural equation models with additive errors and is based on a residual bootstrap procedure to test the goodness-of-fit of causal orderings. We demonstrate the asymptotic validity of the confidence set constructed using this goodness-of-fit test and explain how the confidence set may be used to form sub/supersets of ancestral relationships as well as confidence intervals for causal effects that incorporate model uncertainty.

stat.ME

High-dimensional Functional Graphical Model Structure Learning via Neighborhood Selection Approach

Undirected graphical models are widely used to model the conditional independence structure of vector-valued data. However, in many modern applications, for example those involving EEG and fMRI data, observations are more appropriately modeled as multivariate random functions rather than vectors. Functional graphical models have been proposed to model the conditional independence structure of such functional data. We propose a neighborhood selection approach to estimate the structure of Gaussian functional graphical models, where we first estimate the neighborhood of each node via a function-on-function regression and subsequently recover the entire graph structure by combining the estimated neighborhoods. Our approach only requires assumptions on the conditional distributions of random functions, and we estimate the conditional independence structure directly. We thus circumvent the need for a well-defined precision operator that may not exist when the functions are infinite dimensional. Additionally, the neighborhood selection approach is computationally efficient and can be easily parallelized. The statistical consistency of the proposed method in the high-dimensional setting is supported by both theory and experimental results. In addition, we study the effect of the choice of the function basis used for dimensionality reduction in an intermediate step. We give a heuristic criterion for choosing a function basis and motivate two practically useful choices, which we justify by both theory and experiments.

stat.ML

Gender-based homophily in collaborations across a heterogeneous scholarly landscape

In this article, we investigate the role of gender in collaboration patterns by analyzing gender-based homophily -- the tendency for researchers to co-author with individuals of the same gender. We develop and apply novel methodology to the corpus of JSTOR articles, a broad scholarly landscape, which we analyze at various levels of granularity. Most notably, for a precise analysis of gender homophily, we develop methodology which explicitly accounts for the fact that the data comprises heterogeneous intellectual communities and that not all authorships are exchangeable. In particular, we distinguish three phenomena which may affect the distribution of observed gender homophily in collaborations: a structural component that is due to demographics and non-gendered authorship norms of a scholarly community, a compositional component which is driven by varying gender representation across sub-disciplines and time, and a behavioral component which we define as the remainder of observed gender homophily after its structural and compositional components have been taken into account. Using minimal modeling assumptions, the methodology we develop allows us to test for behavioral homophily. We find that statistically significant behavioral homophily can be detected across the JSTOR corpus and show that this finding is robust to missing gender indicators in our data. In a secondary analysis, we show that the proportion of women representation in a field is positively associated with the probability of finding statistically significant behavioral homophily.

stat.AP

FuDGE: A Method to Estimate a Functional Differential Graph in a High-Dimensional Setting

We consider the problem of estimating the difference between two undirected functional graphical models with shared structures. In many applications, data are naturally regarded as a vector of random functions rather than as a vector of scalars. For example, electroencephalography (EEG) data are treated more appropriately as functions of time. In such a problem, not only can the number of functions measured per sample be large, but each function is itself an infinite-dimensional object, making estimation of model parameters challenging. This is further complicated by the fact that curves are usually observed only at discrete time points. We first define a functional differential graph that captures the differences between two functional graphical models and formally characterize when the functional differential graph is well defined. We then propose a method, FuDGE, that directly estimates the functional differential graph without first estimating each individual graph. This is particularly beneficial in settings where the individual graphs are dense but the differential graph is sparse. We show that FuDGE consistently estimates the functional differential graph even in a high-dimensional setting for both fully observed and discretely observed function paths. We illustrate the finite sample properties of our method through simulation studies. We also propose a competing method, the Joint Functional Graphical Lasso, which generalizes the Joint Graphical Lasso to the functional setting. Finally, we apply our method to EEG data to uncover differences in functional brain connectivity between a group of individuals with alcohol use disorder and a control group.

stat.ML

Causal Discovery with Unobserved Confounding and non-Gaussian Data

We consider recovering causal structure from multivariate observational data. We assume the data arise from a linear structural equation model (SEM) in which the idiosyncratic errors are allowed to be dependent in order to capture possible latent confounding. Each SEM can be represented by a graph where vertices represent observed variables, directed edges represent direct causal effects, and bidirected edges represent dependence among error terms. Specifically, we assume that the true model corresponds to a bow-free acyclic path diagram; i.e., a graph that has at most one edge between any pair of nodes and is acyclic in the directed part. We show that when the errors are non-Gaussian, the exact causal structure encoded by such a graph, and not merely an equivalence class, can be recovered from observational data. The method we propose for this purpose uses estimates of suitable moments, but, in contrast to previous results, does not require specifying the number of latent variables a priori. We also characterize the output of our procedure when the assumptions are violated and the true graph is acyclic, but not bow-free. We illustrate the effectiveness of our procedure in simulations and an application to an ecology data set.

stat.ME

Robust Inference for High-Dimensional Linear Models via Residual Randomization

We propose a residual randomization procedure designed for robust Lasso-based inference in the high-dimensional setting. Compared to earlier work that focuses on sub-Gaussian errors, the proposed procedure is designed to work robustly in settings that also include heavy-tailed covariates and errors. Moreover, our procedure can be valid under clustered errors, which is important in practice, but has been largely overlooked by earlier work. Through extensive simulations, we illustrate our method's wider range of applicability as suggested by theory. In particular, we show that our method outperforms state-of-art methods in challenging, yet more realistic, settings where the distribution of covariates is heavy-tailed or the sample size is small, while it remains competitive in standard, "well behaved" settings previously studied in the literature.

stat.ME

Direct Estimation of Differential Functional Graphical Models

We consider the problem of estimating the difference between two functional undirected graphical models with shared structures. In many applications, data are naturally regarded as high-dimensional random function vectors rather than multivariate scalars. For example, electroencephalography (EEG) data are more appropriately treated as functions of time. In these problems, not only can the number of functions measured per sample be large, but each function is itself an infinite dimensional object, making estimation of model parameters challenging. We develop a method that directly estimates the difference of graphs, avoiding separate estimation of each graph, and show it is consistent in certain high-dimensional settings. We illustrate finite sample properties of our method through simulation studies. Finally, we apply our method to EEG data to uncover differences in functional brain connectivity between alcoholics and control subjects.

stat.ML

High-Dimensional Causal Discovery Under non-Gaussianity

We consider graphical models based on a recursive system of linear structural equations. This implies that there is an ordering, $σ$, of the variables such that each observed variable $Y_v$ is a linear function of a variable specific error term and the other observed variables $Y_u$ with $σ(u) < σ(v)$. The causal relationships, i.e., which other variables the linear functions depend on, can be described using a directed graph. It has been previously shown that when the variable specific error terms are non-Gaussian, the exact causal graph, as opposed to a Markov equivalence class, can be consistently estimated from observational data. We propose an algorithm that yields consistent estimates of the graph also in high-dimensional settings in which the number of variables may grow at a faster rate than the number of observations, but in which the underlying causal structure features suitable sparsity; specifically, the maximum in-degree of the graph is controlled. Our theoretical analysis is couched in the setting of log-concave error distributions.

stat.ME

On Causal Discovery with Equal Variance Assumption

Prior work has shown that causal structure can be uniquely identified from observational data when these follow a structural equation model whose error terms have equal variances. We show that this fact is implied by an ordering among (conditional) variances. We demonstrate that ordering estimates of these variances yields a simple yet state-of-the-art method for causal structure learning that is readily extendable to high-dimensional problems.

stat.ME

On the use of bootstrap with variational inference: Theory, interpretation, and a two-sample test example

Variational inference is a general approach for approximating complex density functions, such as those arising in latent variable models, popular in machine learning. It has been applied to approximate the maximum likelihood estimator and to carry out Bayesian inference, however, quantification of uncertainty with variational inference remains challenging from both theoretical and practical perspectives. This paper is concerned with developing uncertainty measures for variational inference by using bootstrap procedures. We first develop two general bootstrap approaches for assessing the uncertainty of a variational estimate and the study the underlying bootstrap theory in both fixed- and increasing-dimension settings. We then use the bootstrap approach and our theoretical results in the context of mixed membership modeling with multivariate binary data on functional disability from the National Long Term Care Survey. We carry out a two-sample approach to test for changes in the repeated measures of functional disability for the subset of individuals present in 1989 and 1994 waves.

stat.ME

Empirical Likelihood for Linear Structural Equation Models with Dependent Errors

We consider linear structural equation models that are associated with mixed graphs. The structural equations in these models only involve observed variables, but their idiosyncratic error terms are allowed to be correlated and non-Gaussian. We propose empirical likelihood (EL) procedures for inference, and suggest several modifications, including a profile likelihood, in order to improve tractability and performance of the resulting methods. Through simulations, we show that when the error distributions are non-Gaussian, the use of EL and the proposed modifications may increase statistical efficiency and improve assessment of significance.

stat.CO

A Variational EM Method for Mixed Membership Models with Multivariate Rank Data: an Analysis of Public Policy Preferences

In this article, we consider modeling ranked responses from a heterogeneous population. Specifically, we analyze data from the Eurobarometer 34.1 survey regarding public policy preferences towards drugs, alcohol and AIDS. Such policy preferences are likely to exhibit substantial differences within as well as across European nations reflecting a wide variety of cultures, political affiliations, ideological perspectives and common practices. We use a mixed membership model to account for multiple subgroups with differing preferences and to allow each individual to possess partial membership in more than one subgroup. Previous methods for fitting mixed membership models to rank data in a univariate setting have utilized an MCMC approach and do not estimate the relative frequency of each subgroup. We propose a variational EM approach for fitting mixed membership models with multivariate rank data. Our method allows for fast approximate inference and explicitly estimates the subgroup sizes. Analyzing the Eurobarometer 34.1 data, we find interpretable subgroups which generally agree with the "left vs right" classification of political ideologies.

stat.ME

On the relationship between set-based and network-based measures of gender homophily in scholarly publications

There is an increased interest in the scientific community in the problem of measuring gender homophily in co-authorship on scholarly publications (Eisen, 2016). For a given set of publications and co-authorships, we assume that author identities have not been disambiguated in that we do not know when one person is an author on more than one paper. In this case, one way to think about measuring gender homophily is to consider all observed co-authorship pairs and obtain a set-based gender homophily coefficient (e.g., Bergstrom et al., 2016). Another way is to consider papers as observed disjoint networks of co-authors and use a network-based assortativity coefficient (e.g., Newman, 2003). In this note, we review both metrics and show that the gender homophily set-based index is equivalent to the gender assortativity network-based coefficient with properly weighted edges.

cs.DL

Computation of maximum likelihood estimates in cyclic structural equation models

Software for computation of maximum likelihood estimates in linear structural equation models typically employs general techniques from non-linear optimization, such as quasi-Newton methods. In practice, careful tuning of initial values is often required to avoid convergence issues. As an alternative approach, we propose a block-coordinate descent method that cycles through the considered variables, updating only the parameters related to a given variable in each step. We show that the resulting block update problems can be solved in closed form even when the structural equation model comprises feedback cycles. Furthermore, we give a characterization of the models for which the block-coordinate descent algorithm is well-defined, meaning that for generic data and starting values all block optimization problems admit a unique solution. For the characterization, we represent each model by its mixed graph (also known as path diagram), which leads to criteria that can be checked in time that is polynomial in the number of considered variables.

stat.CO