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Yafang Deng

Publications and source records attributed to Yafang Deng.

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Apportioning Causal Responsibility of Two Risk Factors for an Adverse Outcome via Counterfactual Attribution

Unlike traditional causal inference, which prospectively evaluates the effects of causes, apportioning causal responsibility requires a retrospective assessment to deduce the causes of an outcome that has already occurred. This paper proposes a quantitative framework for apportioning causal responsibility between two binary risk factors that jointly contribute to a realized adverse outcome. Ideally, knowing the individual's latent causal type, defined by the potential outcomes under all possible exposure combinations, would allow precise apportionment; however, these potential outcomes cannot be simultaneously observed. We therefore define the average causal responsibility of each risk factor as its expected responsibility over the distribution of latent causal types. Under the assumptions of no confounding and monotonicity, we establish nonparametric identification of this metric when the type-specific responsibilities satisfy a structural balance condition, and derive sharp bounds otherwise. We illustrate the proposed framework using the classic example of lung cancer attributable to smoking and asbestos exposures.

stat.ME

Bidirectional causal inference for binary outcomes in the presence of unmeasured confounding

Bidirectional causal relationships arising from mutual interactions between variables are commonly observed within biomedical, econometrical, and social science contexts. When such relationships are further complicated by unobserved factors, identifying causal effects in both directions becomes especially challenging. For continuous variables, methods that utilize two instrumental variables from both directions have been proposed to explore bidirectional causal effects in linear models. However, the existing techniques are not applicable when the key variables of interest are binary. To address these issues, we propose a structural equation modeling approach that links observed binary variables to continuous latent variables through a constrained mapping. We further establish identification results for bidirectional causal effects using a pair of instrumental variables. Additionally, we develop an estimation method for the corresponding causal parameters. We also conduct sensitivity analysis under scenarios where certain identification conditions are violated. Finally, we apply our approach to investigate the bidirectional causal relationship between heart disease and diabetes, demonstrating its practical utility in biomedical research.

stat.ME