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Yang-Hsien Lin

Publications and source records attributed to Yang-Hsien Lin.

4 recordsLinked to original sources

TASTE2: Text-Aligned Speech Modeling and Deployment toward Full-Duplex Voice Interaction

Full-duplex voice interaction requires more than utterance-level conversion. It must process streaming speech, manage turn-taking and interruptions, while preserving pretrained linguistic competence and acoustic paralinguistic cues. We ask whether TASTE (Text-Aligned Speech Tokenization and Embedding) provides a viable path toward this goal. We present TASTE2, which transforms utterance-level TASTE into an incremental dialogue stack. A shared text-token vocabulary removes word-level averaging, while modality-aligned dialogue training predicts one continuous audio latent per text token without interleaving heterogeneous token streams. An incremental Speech Detokenizer enables streaming synthesis through CosyVoice2. After speech and dialogue training, TASTE2 (Merge) reaches 56.3% on LLaMA-Questions against a 57.3% Qwen2.5-7B Instruct text-only reference (98.2% accuracy retention), and TASTE2 (Direct) reaches 53.0% (92.4% retention). We build TASTE2 VoiceBot, which processes user speech incrementally, streams synthesized audio, and stops generation on barge-in. On Full-Duplex-Bench v1.0, TASTE2 and TASTE2 VoiceBot handle interruptions well while maintaining high conversational coherence. Natural conversation remains challenging, and deployed mean time to first audio is 2.701 s on two NVIDIA RTX A6000 after TensorRT acceleration. Finally, to our knowledge, we provide the first systematic characterization of explicit paralinguistic control in a TASTE based model. Fast speaking rate serves as a cross-strategy proof of concept after dialogue SFT, while emotion control is strategy dependent and the remaining attributes stay weak. Together, these results establish TASTE based modeling as a practical route toward full-duplex systems while identifying natural conversation robustness, speech generation latency, and feature general paralinguistic control as open challenges. Explore TASTE2 online.

cs.SD

NVAITC AI Scientist: A Governed End-to-End Research System -- A Hypertension GWAS Case Study

Agentic research systems are emerging as a new paradigm for coordinating scientific workflows beyond isolated model inference, code generation, or statistical analysis. However, deployment in institutional biomedical environments requires governed mechanisms for research planning, data access, workflow orchestration, evidence tracking, reproducibility, and human oversight. We present NVAITC AI Scientist (NAIS), a governed end-to-end agentic research system designed to support domain-general scientific workflows while keeping protected data within institutional privacy boundaries. NAIS integrates proposal review, execution planning, governed computational routing, reproducible workflow orchestration, evidence generation, and scientist-in-the-loop oversight. We validate NAIS in a real-world hypertension genome-wide association study (GWAS) using hospital-linked genotype and electronic health record (EHR) data from 286,422 individuals under an aggregate-only data policy. The agent planned cohort extraction, orchestrated GWAS execution, generated quality-control summaries, and drafted publication-oriented outputs. Human-AI review identified phenotype discrepancies and enabled iterative refinement of the hypertension definition. After reconciliation, the agent-orchestrated GWAS reproduced established hypertension loci, including FGF5, ATP2B1, CNNM2, FTO, and GRB14, with the strongest signal at FGF5 reaching $-\log_{10}(p) \sim 70$. As a secondary demonstration, NAIS also supported a drug-induced liver injury prediction workflow, achieving a multimodal graph neural network AUC of 0.842. These results demonstrate that governed agentic research systems can support scalable AI-assisted biomedical discovery while producing outputs comparable to expert-led workflows.

cs.AI

Continual Pre-Training is (not) What You Need in Domain Adaption

The recent advances in Legal Large Language Models (LLMs) have transformed the landscape of legal research and practice by automating tasks, enhancing research precision, and supporting complex decision-making processes. However, effectively adapting LLMs to the legal domain remains challenging due to the complexity of legal reasoning, the need for precise interpretation of specialized language, and the potential for hallucinations. This paper examines the efficacy of Domain-Adaptive Continual Pre-Training (DACP) in improving the legal reasoning capabilities of LLMs. Through a series of experiments on legal reasoning tasks within the Taiwanese legal framework, we demonstrate that while DACP enhances domain-specific knowledge, it does not uniformly improve performance across all legal tasks. We discuss the trade-offs involved in DACP, particularly its impact on model generalization and performance in prompt-based tasks, and propose directions for future research to optimize domain adaptation strategies in legal AI.

cs.CL

Combining optical diffraction tomography with imaging flow cytometry for characterizing morphology, hemoglobin content, and membrane deformability of live red blood cells

Integrating optical diffraction tomography with imaging flow cytometry enables label-free quantifications of the three-dimensional (3D) morphology and hemoglobin content of red blood cells (RBCs) in their natural form. Self-rotation of RBCs flowing in a microfluidic channel has been utilized to achieve various projection directions for 3D reconstruction. However, the practicality of this technique has not been sufficiently studied. We improved the accuracy of estimating the rotation angle of RBCs and demonstrated 3D reconstructions of both healthy and glutaraldehyde-treated RBCs. Results showed the capability to quantify changes in RBC morphology, hemoglobin content, and membrane fluctuations generated by glutaraldehyde treatments, demonstrating the potential to detect changes frequently present in various RBC membrane disorders.

physics.med-ph