arXiv subjects

Yangjianchen Xu

Publications and source records attributed to Yangjianchen Xu.

3 recordsLinked to original sources

arXiv2026

Functional Cox model for interval-censored data

Interval-censored data arise frequently in scientific studies, where the event of interest is known only to occur within a specific time interval. In such studies, functional covariates taking the form of continuous curves or spatial profiles are increasingly encountered, and it is of substantial scientific relevance to investigate how the trajectory of a functional covariate affects the event time. We formulate the effects of both scalar and functional covariates on the interval-censored event time through a functional Cox model. We consider penalized maximum likelihood estimation for this model and devise an EM algorithm to stably compute the parameter estimators. The resulting estimators for the regression parameters and linear functionals of the coefficient function are shown to be consistent and asymptotically normal, with limiting covariance matrices that attain the semiparametric efficiency bound and can be readily estimated through the profile likelihood method. Building upon these results, we construct a global test for the overall effect of the functional covariate. Finally, we assess the performance of the proposed methods through extensive simulation studies and present an application to data from the Alzheimer's Disease Neuroimaging Initiative.

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arXiv2026

A goodness-of-fit test for the logistic propensity score model under nonignorable missing data

Logistic regression is widely used to model the propensity score in the analysis of nonignorable missing data. However, goodness-of-fit testing for this propensity score model has received limited attention in the literature. In this paper, we propose a new goodness-of-fit testing procedure for the logistic propensity score model under nonignorable missing data. The proposed test is based on an unweighted sum-of-squared residuals constructed from the marginal missingness mechanism and accommodates the partial observability of the outcome. We establish the asymptotic distribution of the test statistic under both the null hypothesis and general alternatives, and develop a bootstrap procedure with theoretical guarantees to approximate its null distribution. We show that the resulting bootstrap test attains asymptotically correct size and is consistent, with power converging to one under model misspecification. Simulation studies and a real data application demonstrate that the proposed method performs well in finite samples.

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arXiv2026

Varying coefficient model for longitudinal data with informative observation times

Varying coefficient models are widely used to characterize dynamic associations between longitudinal outcomes and covariates. Existing work on varying coefficient models, however, all assumes that observation times are independent of the longitudinal outcomes, which is often violated in real-world studies with outcome-driven or otherwise informative visit schedules. Such informative observation times can lead to biased estimation and invalid inference using existing methods. In this article, we develop estimation and inference procedures for varying coefficient models that account for informative observation times. We model the observation time process as a general counting process under a proportional intensity model, with time-varying covariates summarizing the observed history. To address potential bias, we incorporate inverse intensity weighting into a sieve estimation framework, yielding closed-form coefficient function estimators via weighted least squares. We establish consistency, convergence rates, and asymptotic normality of the proposed estimators, and construct pointwise confidence intervals for the coefficient functions. Extensive simulation studies demonstrate that the proposed weighted method substantially outperforms the conventional unweighted method when observation times are informative. Finally, we provide an application of our method to the Alzheimer's Disease Neuroimaging Initiative study.

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