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Yangyang Yuan

Publications and source records attributed to Yangyang Yuan.

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Understanding of Task-specific and Subject-specific Components in Surface EMG

Surface electromyogram (sEMG) signals are widely used in human-machine interfaces for gesture recognition and user identification, but existing models often struggle to generalize across individuals due to subject-specific neuromuscular characteristics. This study introduces a disentanglement model that separates task-specific and subject-specific components from sEMG signals, thereby improving the generalization and interpretability of gesture recognition and user identification systems. Experimental results demonstrate that the disentangled components significantly improve the accuracy of both gesture classification and user identification across subjects and days, outperforming conventional methods under the same experimental conditions. Further analysis reveals that the task-specific components capture consistent activation patterns associated with the same gestures across individuals. In contrast, the subject-specific components reflect unique neuromuscular characteristics that can be used for user identification. Notably, the subject-specific components show lower similarity across days than the task-specific components, contributing to a greater decrease in user identification accuracy than in gesture recognition accuracy. These findings suggest that the disentanglement approach not only improves classification performance but also provides deeper insights into the physiological mechanisms underlying sEMG signals. The model's ability to isolate and interpret different neuromuscular components holds promise for enhancing the robustness of sEMG-based applications in real-world settings, including rehabilitation and user authentication. Our code is available at https://github.com/Open-EXG/HandDisentanglement.

cs.HC

Fronto-parietal and fronto-temporal EEG coherence as predictive neuromarkers of transcutaneous auricular vagus nerve stimulation response in treatment-resistant schizophrenia: A machine learning study

Response variability limits the clinical utility of transcutaneous auricular vagus nerve stimulation (taVNS) for negative symptoms in treatment-resistant schizophrenia (TRS). This study aimed to develop an electroencephalography (EEG)-based machine learning (ML) model to predict individual response and explore associated neurophysiological mechanisms. We used ML to develop and validate predictive models based on pre-treatment EEG data features (power, coherence, and dynamic functional connectivity) from 50 TRS patients enrolled in the taVNS trial, within a nested cross-validation framework. Participants received 20 sessions of active or sham taVNS (n = 25 each) over two weeks, followed by a two-week follow-up. The prediction target was the percentage change in the positive and negative syndrome scale-factor score for negative symptoms (PANSS-FSNS) from baseline to post-treatment, with further evaluation of model specificity and neurophysiological relevance.The optimal model accurately predicted taVNS response in the active group, with predicted PANSS-FSNS changes strongly correlated with observed changes (r = 0.87, p < .001); permutation testing confirmed performance above chance (p < .001). Nine consistently retained features were identified, predominantly fronto-parietal and fronto-temporal coherence features. Negligible predictive performance in the sham group and failure to predict positive symptom change support the predictive specificity of this oscillatory signature for taVNS-related negative symptom improvement. Two coherence features within fronto-parietal-temporal networks showed post-taVNS changes significantly associated with symptom improvement, suggesting dual roles as predictors and potential therapeutic targets. EEG oscillatory neuromarkers enable accurate prediction of individual taVNS response in TRS, supporting mechanism-informed precision neuromodulation strategies.

cs.LG