arXiv subjects

Yanhui Hu

Publications and source records attributed to Yanhui Hu.

5 recordsLinked to original sources

arXiv2026

Optomechanical Levitation and Control of High Aspect Ratio Silicon Nanorods

Nano- and micro-particles levitated by optical, electrical or magnetic fields are a new frontier in precision sensing and for tests of fundamental physics. For optically levitated anisotropic particles it is possible to control their translation, alignment and rotation. We report on the levitation and characterization of nanofabricated, high uniformity, high aspect ratio, high refractive index silicon cylinders, with diameters as low as 50 nm and lengths up to 1500 nm. We are able to tune their oscillation frequencies from 10 kHz to over 1 MHz, and exert huge optical torque to generate high rotation rates. These optically levitated silicon nanorods will enable precision torque sensing, and when pushed to smaller sizes, tests of quantum physics through the generation of angular momentum superposition states.

physics.optics↗

arXiv2022

Ultrasensitive atomic comagnetometer with enhanced nuclear spin coherence

Achieving high energy resolution in spin systems is important for fundamental physics research and precision measurements, with alkali-noble-gas comagnetometers being among the best available sensors. We found a new relaxation mechanism in such devices, the gradient of the Fermi-contact-interaction field that dominates the relaxation of hyperpolarized nuclear spins. We report on precise control over spin distribution, demonstrating a tenfold increase of nuclear spin hyperpolarization and transverse coherence time with optimal hybrid optical pumping. Operating in the self-compensation regime, our $^{21}$Ne-Rb-K comagnetometer achieves an ultrahigh inertial rotation sensitivity of $3\times10^{-8}$\,rad/s/Hz$^{1/2}$ in the frequency range from 0.2 to 1.0 Hz, which is equivalent to the energy resolution of $3.1\times 10^{-23}$\,eV/Hz$^{1/2}$. We propose to use this comagnetometer to search for exotic spin-dependent interactions involving proton and neutron spins. The projected sensitivity surpasses the previous experimental and astrophysical limits by more than four orders of magnitude.

physics.atom-ph↗

arXiv2022

Structured transverse orbital angular momentum probed by a levitated optomechanical sensor

The momentum carried by structured light fields exhibits a rich array of surprising features. In this work, we generate transverse orbital angular momentum (TOAM) in the interference field of two parallel and counterpropagating linearly-polarised focused beams, synthesising an array of identical handedness vortices carrying intrinsic TOAM. We explore this structured light field using an optomechanical sensor, consisting of an optically levitated silicon nanorod, whose rotation is a probe of the optical angular momentum, which generates an exceptionally large torque. This simple creation and direct observation of TOAM will have applications in studies of fundamental physics, the optical manipulation of matter and quantum optomechanics.

physics.optics↗

arXiv2021

Direct and clean loading of nanoparticles into optical traps at millibar pressures

Nanoparticles levitated by optical fields under vacuum conditions have applications in quantum science, the study of nanothermodynamics and precision sensing. Existing techniques for loading optical traps require ambient conditions, and often involve dispersion in liquids, which can contaminate delicate optics and lead to enhanced optical absorption and heating. Here we present a clean, dry and generic mechanism for directly loading optical traps at pressures down to 1\,mbar, exploiting Laser Induced Acoustic Desorption. Our method allows rapid and efficient trapping, and is also suitable for site-selective loading of nanofabricated particles grown on a silicon substrate.

quant-ph↗

arXiv2015

Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets

The protein-protein interaction (PPI) network is crucial for cellular information processing and decision-making. With suitable inputs, PPI networks drive the cells to diverse functional outcomes such as cell proliferation or cell death. Here we characterize the structural controllability of a large directed human PPI network comprised of 6,339 proteins and 34,813 interactions. This allows us to classify proteins as "indispensable", "neutral" or "dispensable", which correlates to increasing, no effect, or decreasing the number of driver nodes in the network upon removal of that protein. We find that 21% of the proteins in the PPI network are indispensable. Interestingly, these indispensable proteins are the primary targets of disease-causing mutations, human viruses, and drugs, suggesting that altering a network's control property is critical for the transition between healthy and disease states. Furthermore, analyzing copy number alterations data from 1,547 cancer patients reveals that 56 genes that are frequently amplified or deleted in nine different cancers are indispensable. Among the 56 genes, 46 of them have not been previously associated with cancer. This suggests that controllability analysis is very useful in identifying novel disease genes and potential drug targets.

q-bio.MN↗