arXiv subjects

Yao Chen

Publications and source records attributed to Yao Chen.

At least 73 records · Page 4Linked to original sources

arXiv2025

WATCH: A Workflow to Assess Treatment Effect Heterogeneity in Drug Development for Clinical Trial Sponsors

This paper proposes a Workflow for Assessing Treatment effeCt Heterogeneity (WATCH) in clinical drug development targeted at clinical trial sponsors. WATCH is designed to address the challenges of investigating treatment effect heterogeneity (TEH) in randomized clinical trials, where sample size and multiplicity limit the reliability of findings. The proposed workflow includes four steps: Analysis Planning, Initial Data Analysis and Analysis Dataset Creation, TEH Exploration, and Multidisciplinary Assessment. The workflow offers a general overview of how treatment effects vary by baseline covariates in the observed data, and guides interpretation of the observed findings based on external evidence and best scientific understanding. The workflow is exploratory and not inferential/confirmatory in nature, but should be pre-planned before data-base lock and analysis start. It is focused on providing a general overview rather than a single specific finding or subgroup with differential effect.

stat.AP↗

arXiv2024

The magnetic origin of the mystery of rare H$α$ Moreton waves

Over the past three decades, a lot of coronal fast-mode waves were detected by space missions, but their counterparts in the chromosphere, called the Moreton waves, were rarely captured. How this happens remains a mystery. Here, to shed light on this problem, we investigate the photospheric vector magnetograms of the Moreton wave events associated with M- and X-class solar flares in 2010--2023. The H$α$ data are taken with the Global Oscillation Network Group (GONG) and the Chinese H$α$ Solar Explorer (CHASE). Our statistical results show that more than 80\% of the events occur at the edge of active regions and propagate non-radially due to asymmetric magnetic fields above the flares. According to the reconstructed magnetic field and atmospheric model, Moreton waves propagate in the direction along which the horizontal fast-mode wave speed drops the fastest. The result supports that the inclined magnetic configuration of the eruption is crucial to generate Moreton waves, even for X-class flares. It may explain the low occurrence rate of Moreton waves and why some X-class flares accompanied with coronal mass ejections (CMEs) do not generate Moreton waves.

astro-ph.SR↗

arXiv2024

T-Edge: Trusted Heterogeneous Edge Computing

Heterogeneous computing, which incorporates GPUs, NPUs, and FPGAs, is increasingly utilized to improve the efficiency of computer systems. However, this shift has given rise to significant security and privacy concerns, especially when the execution platform is remote. One way to tackle these challenges is to establish a trusted and isolated environment for remote program execution, while maintaining minimal overhead and flexibility. While CPU-based trusted execution has been extensively explored and found commercial success, extension to heterogeneous computing systems remains a challenge. This paper proposes a practical trusted execution environment design for ARM/FPGA System-on-Chip platforms, leveraging TrustZone's unique characteristics. The design features a dedicated security controller within the ARM TrustZone, overseeing FPGA reconfiguration and managing communication between CPU cores and FPGA fabrics. This design involves a provisioning service that enables application users to establish trust in the FPGA fabric within cloud-based computing resources provided by the platform owner, running applications developed by third-party developers and hardware manufactured by the device manufacturer. To ensure the security of our proposed system, we employ an automated protocol verifier, ProVerif, to validate its compliance with essential security requirements. Furthermore, we demonstrate the practicality of our system model by implementing a prototype application on the Xilinx MPSoC development board.

cs.CR↗

arXiv2024

ASLoRA: Adaptive Sharing Low-Rank Adaptation Across Layers

As large language models (LLMs) grow in size, traditional full fine-tuning becomes increasingly impractical due to its high computational and storage costs. Although popular parameter-efficient fine-tuning methods, such as LoRA, have significantly reduced the number of tunable parameters, there is still room for further optimization. In this work, we propose ASLoRA, a cross-layer parameter-sharing strategy combining global sharing with partial adaptive sharing. Specifically, we share the low-rank matrix A across all layers and adaptively merge matrix B during training. This sharing mechanism not only mitigates overfitting effectively but also captures inter-layer dependencies, significantly enhancing the model's representational capability. We conduct extensive experiments on various NLP tasks, showing that ASLoRA outperforms LoRA while using less than 25% of the parameters, highlighting its flexibility and superior parameter efficiency. Furthermore, in-depth analyses of the adaptive sharing strategy confirm its significant advantages in enhancing both model flexibility and task adaptability.

cs.CL↗

arXiv2024

Vision Mamba Distillation for Low-resolution Fine-grained Image Classification

Low-resolution fine-grained image classification has recently made significant progress, largely thanks to the super-resolution techniques and knowledge distillation methods. However, these approaches lead to an exponential increase in the number of parameters and computational complexity of models. In order to solve this problem, in this letter, we propose a Vision Mamba Distillation (ViMD) approach to enhance the effectiveness and efficiency of low-resolution fine-grained image classification. Concretely, a lightweight super-resolution vision Mamba classification network (SRVM-Net) is proposed to improve its capability for extracting visual features by redesigning the classification sub-network with Mamba modeling. Moreover, we design a novel multi-level Mamba knowledge distillation loss boosting the performance, which can transfer prior knowledge obtained from a High-resolution Vision Mamba classification Network (HRVM-Net) as a teacher into the proposed SRVM-Net as a student. Extensive experiments on seven public fine-grained classification datasets related to benchmarks confirm our ViMD achieves a new state-of-the-art performance. While having higher accuracy, ViMD outperforms similar methods with fewer parameters and FLOPs, which is more suitable for embedded device applications. Code is available at https://github.com/boa2004plaust/ViMD.

cs.CV↗

arXiv2024

Paying more attention to local contrast: improving infrared small target detection performance via prior knowledge

The data-driven method for infrared small target detection (IRSTD) has achieved promising results. However, due to the small scale of infrared small target datasets and the limited number of pixels occupied by the targets themselves, it is a challenging task for deep learning methods to directly learn from these samples. Utilizing human expert knowledge to assist deep learning methods in better learning is worthy of exploration. To effectively guide the model to focus on targets' spatial features, this paper proposes the Local Contrast Attention Enhanced infrared small target detection Network (LCAE-Net), combining prior knowledge with data-driven deep learning methods. LCAE-Net is a U-shaped neural network model which consists of two developed modules: a Local Contrast Enhancement (LCE) module and a Channel Attention Enhancement (CAE) module. The LCE module takes advantages of prior knowledge, leveraging handcrafted convolution operator to acquire Local Contrast Attention (LCA), which could realize background suppression while enhance the potential target region, thus guiding the neural network to pay more attention to potential infrared small targets' location information. To effectively utilize the response information throughout downsampling progresses, the CAE module is proposed to achieve the information fusion among feature maps' different channels. Experimental results indicate that our LCAE-Net outperforms existing state-of-the-art methods on the three public datasets NUDT-SIRST, NUAA-SIRST, and IRSTD-1K, and its detection speed could reach up to 70 fps. Meanwhile, our model has a parameter count and Floating-Point Operations (FLOPs) of 1.945M and 4.862G respectively, which is suitable for deployment on edge devices.

cs.CV↗

arXiv2024

Graph-Augmented Relation Extraction Model with LLMs-Generated Support Document

This study introduces a novel approach to sentence-level relation extraction (RE) that integrates Graph Neural Networks (GNNs) with Large Language Models (LLMs) to generate contextually enriched support documents. By harnessing the power of LLMs to generate auxiliary information, our approach crafts an intricate graph representation of textual data. This graph is subsequently processed through a Graph Neural Network (GNN) to refine and enrich the embeddings associated with each entity ensuring a more nuanced and interconnected understanding of the data. This methodology addresses the limitations of traditional sentence-level RE models by incorporating broader contexts and leveraging inter-entity interactions, thereby improving the model's ability to capture complex relationships across sentences. Our experiments, conducted on the CrossRE dataset, demonstrate the effectiveness of our approach, with notable improvements in performance across various domains. The results underscore the potential of combining GNNs with LLM-generated context to advance the field of relation extraction.

cs.CL↗

arXiv2024

Aggressive Post-Training Compression on Extremely Large Language Models

The increasing size and complexity of Large Language Models (LLMs) pose challenges for their deployment on personal computers and mobile devices. Aggressive post-training model compression is necessary to reduce the models' size, but it often results in significant accuracy loss. To address this challenge, we propose a novel network pruning technology that utilizes over 0.7 sparsity and less than 8 bits of quantization. Our approach enables the compression of prevailing LLMs within a couple of hours while maintaining a relatively small accuracy loss. In experimental evaluations, our method demonstrates effectiveness and potential for practical deployment. By making LLMs available on domestic devices, our work can facilitate a new era of natural language processing applications with wide-ranging impacts.

cs.CL↗

arXiv2024

Alpha-Proton Differential Flow of A Coronal Mass Ejection at 15 Solar Radii

Alpha-proton differential flow ($V_{αp}$) of coronal mass ejections (CMEs) and solar wind from the Sun to 1 au and beyond could influence the instantaneous correspondence of absolute abundances of alpha particles (He$^{2+}$/H$^{+}$) between solar corona and interplanetary space as the abundance of a coronal source can vary with time. Previous studies based on Ulysses and Helios showed that $V_{αp}$ is negligible within CMEs from 5 to 0.3 au, similar to slow solar wind ($<$ 400 km s$^{-1}$). However, recent new observations using Parker Solar Probe (PSP) revealed that the $V_{αp}$ of slow wind increases to $\sim$60 km s$^{-1}$ inside 0.1 au. It is significant to answer whether the $V_{αp}$ of CMEs exhibits the similar behavior near the Sun. In this Letter, we report the $V_{αp}$ of a CME measured by PSP at $\sim$15 $R_\odot$ for the first time, which demonstrates that the $V_{αp}$ of CMEs is obvious and complex inside 0.1 au while keeps lower than the local Alfvén speed. A very interesting point is that the same one CME duration can be divided into A and B intervals clearly with Coulomb number below and beyond 0.5, respectively. The means of $V_{αp}$ and alpha-to-proton temperature ratios of interval A (B) is 96.52 (21.96) km s$^{-1}$ and 7.65 (2.23), respectively. This directly illustrates that Coulomb collisions play an important role in reducing the non-equilibrium features of CMEs. Our study indicates that the absolute elemental abundances of CMEs also might vary during their propagation.

astro-ph.SR↗

arXiv2024

Robust Real-time Segmentation of Bio-Morphological Features in Human Cherenkov Imaging during Radiotherapy via Deep Learning

Cherenkov imaging enables real-time visualization of megavoltage X-ray or electron beam delivery to the patient during Radiation Therapy (RT). Bio-morphological features, such as vasculature, seen in these images are patient-specific signatures that can be used for verification of positioning and motion management that are essential to precise RT treatment. However until now, no concerted analysis of this biological feature-based tracking was utilized because of the slow speed and accuracy of conventional image processing for feature segmentation. This study demonstrated the first deep learning framework for such an application, achieving video frame rate processing. To address the challenge of limited annotation of these features in Cherenkov images, a transfer learning strategy was applied. A fundus photography dataset including 20,529 patch retina images with ground-truth vessel annotation was used to pre-train a ResNet segmentation framework. Subsequently, a small Cherenkov dataset (1,483 images from 212 treatment fractions of 19 breast cancer patients) with known annotated vasculature masks was used to fine-tune the model for accurate segmentation prediction. This deep learning framework achieved consistent and rapid segmentation of Cherenkov-imaged bio-morphological features on another 19 patients, including subcutaneous veins, scars, and pigmented skin. Average segmentation by the model achieved Dice score of 0.85 and required less than 0.7 milliseconds processing time per instance. The model demonstrated outstanding consistency against input image variances and speed compared to conventional manual segmentation methods, laying the foundation for online segmentation in real-time monitoring in a prospective setting.

eess.IV↗

arXiv2024

Local Conditional Controlling for Text-to-Image Diffusion Models

Diffusion models have exhibited impressive prowess in the text-to-image task. Recent methods add image-level structure controls, e.g., edge and depth maps, to manipulate the generation process together with text prompts to obtain desired images. This controlling process is globally operated on the entire image, which limits the flexibility of control regions. In this paper, we explore a novel and practical task setting: local control. It focuses on controlling specific local region according to user-defined image conditions, while the remaining regions are only conditioned by the original text prompt. However, it is non-trivial to achieve local conditional controlling. The naive manner of directly adding local conditions may lead to the local control dominance problem, which forces the model to focus on the controlled region and neglect object generation in other regions. To mitigate this problem, we propose Regional Discriminate Loss to update the noised latents, aiming at enhanced object generation in non-control regions. Furthermore, the proposed Focused Token Response suppresses weaker attention scores which lack the strongest response to enhance object distinction and reduce duplication. Lastly, we adopt Feature Mask Constraint to reduce quality degradation in images caused by information differences across the local control region. All proposed strategies are operated at the inference stage. Extensive experiments demonstrate that our method can synthesize high-quality images aligned with the text prompt under local control conditions.

cs.CV↗

arXiv2024

Deep Feature Surgery: Towards Accurate and Efficient Multi-Exit Networks

Multi-exit network is a promising architecture for efficient model inference by sharing backbone networks and weights among multiple exits. However, the gradient conflict of the shared weights results in sub-optimal accuracy. This paper introduces Deep Feature Surgery (\methodname), which consists of feature partitioning and feature referencing approaches to resolve gradient conflict issues during the training of multi-exit networks. The feature partitioning separates shared features along the depth axis among all exits to alleviate gradient conflict while simultaneously promoting joint optimization for each exit. Subsequently, feature referencing enhances multi-scale features for distinct exits across varying depths to improve the model accuracy. Furthermore, \methodname~reduces the training operations with the reduced complexity of backpropagation. Experimental results on Cifar100 and ImageNet datasets exhibit that \methodname~provides up to a \textbf{50.00\%} reduction in training time and attains up to a \textbf{6.94\%} enhancement in accuracy when contrasted with baseline methods across diverse models and tasks. Budgeted batch classification evaluation on MSDNet demonstrates that DFS uses about $\mathbf{2}\boldsymbol{\times}$ fewer average FLOPs per image to achieve the same classification accuracy as baseline methods on Cifar100. The code is available at https://github.com/GongCheng1919/dfs.

cs.CV↗

arXiv2024

LoRA-Composer: Leveraging Low-Rank Adaptation for Multi-Concept Customization in Training-Free Diffusion Models

Customization generation techniques have significantly advanced the synthesis of specific concepts across varied contexts. Multi-concept customization emerges as the challenging task within this domain. Existing approaches often rely on training a fusion matrix of multiple Low-Rank Adaptations (LoRAs) to merge various concepts into a single image. However, we identify this straightforward method faces two major challenges: 1) concept confusion, where the model struggles to preserve distinct individual characteristics, and 2) concept vanishing, where the model fails to generate the intended subjects. To address these issues, we introduce LoRA-Composer, a training-free framework designed for seamlessly integrating multiple LoRAs, thereby enhancing the harmony among different concepts within generated images. LoRA-Composer addresses concept vanishing through concept injection constraints, enhancing concept visibility via an expanded cross-attention mechanism. To combat concept confusion, concept isolation constraints are introduced, refining the self-attention computation. Furthermore, latent re-initialization is proposed to effectively stimulate concept-specific latent within designated regions. Our extensive testing showcases a notable enhancement in LoRA-Composer's performance compared to standard baselines, especially when eliminating the image-based conditions like canny edge or pose estimations. Code is released at \url{https://github.com/Young98CN/LoRA_Composer}

cs.CV↗

arXiv2024

Prevalence of non-standard collapsing of strong Langmuir turbulence in solar corona plasmas

We present a fully-kinetic simulation of the full life cycle of strong Langmuir turbulence (SLT) excited by electron beams that are accelerated under the solar corona conditions. We find that (1) most packets ($\sim$80%) are affected by their neighbors during their collapse, as a result, their spatial scale variations present non-standard evolutionary features, i.e., deviating away from what was predicted by the Zakharov model; (2) the collapsing cavity is too shallow to trap the wave packet due to the growth of the Coulomb force, as a result a majority ($\sim$70%) of the packet energy runs away and a secondary localization may occur. The study indicates that the non-standard Langmuir collapse may play an important role in coronal plasmas interacting with an intense electron beam, that may be eventually confirmed by humanity's first mission to fly through the corona.

astro-ph.SR↗

arXiv2024

Electron acceleration and transport in the 2023-03-06 solar flare

We investigated in detail the M5.8 class solar flare that occurred on 2023-03-06. This flare was one of the first strong flares observed by the Siberian Radioheliograph in the microwave range and the Advanced Space-based Solar Observatory in the X-ray range. The flare consisted of two separate flaring events (a "thermal" and a "cooler" ones), and was associated with (and probably triggered by) a filament eruption. During the first part of the flare, the microwave emission was produced in an arcade of relatively short and low flaring loops. During the second part of the flare, the microwave emission was produced by energetic electrons trapped near the top of a large-scale flaring loop; the evolution of the trapped electrons was mostly affected by the Coulomb collisions. Using the available observations and the GX Simulator tool, we created a 3D model of the flare, and estimated the parameters of the energetic electrons in it.

astro-ph.SR↗

arXiv2024

HiKonv: Maximizing the Throughput of Quantized Convolution With Novel Bit-wise Management and Computation

Quantization for CNN has shown significant progress with the intention of reducing the cost of computation and storage with low-bitwidth data representations. There are, however, no systematic studies on how an existing full-bitwidth processing unit, such as ALU in CPUs and DSP in FPGAs, can be better utilized to deliver significantly higher computation throughput for convolution under various quantized bitwidths. In this study, we propose HiKonv, a unified solution that maximizes the throughput of convolution on a given underlying processing unit with low-bitwidth quantized data inputs through novel bit-wise management and parallel computation. We establish theoretical framework and performance models using a full-bitwidth multiplier for highly parallelized low-bitwidth convolution, and demonstrate new breakthroughs for high-performance computing in this critical domain. For example, a single 32-bit processing unit in CPU can deliver 128 binarized convolution operations (multiplications and additions) and 13 4-bit convolution operations with a single multiplication instruction, and a single 27x18 multiplier in the FPGA DSP can deliver 60, 8 or 2 convolution operations with 1, 4 or 8-bit inputs in one clock cycle. We demonstrate the effectiveness of HiKonv on both CPU and FPGA. On CPU, HiKonv outperforms the baseline implementation with 1 to 8-bit inputs and provides up to 7.6x and 1.4x performance improvements for 1-D convolution, and performs 2.74x and 3.19x over the baseline implementation for 4-bit signed and unsigned data inputs for 2-D convolution. On FPGA, HiKonv solution enables a single DSP to process multiple convolutions with a shorter processing latency. For binarized input, each DSP with HiKonv is equivalent up to 76.6 LUTs. Compared to the DAC-SDC 2020 champion model, HiKonv achieves a 2.37x throughput improvement and 2.61x DSP efficiency improvement, respectively.

cs.AR↗

arXiv2024

A Multi-Peak Solar Flare with a High Turnover Frequency of The Gyrosynchrotron Spectra from the Loop-Top Source

The origin of multiple peaks in lightcurves of various wavelengths remains illusive during flares. Here we discuss the flare of SOL2023-05-09T03:54M6.5 with six flux peaks as recorded by a tandem of new microwave and Hard X-ray instruments. According to its microwave spectra, the flare represents a high-turnover frequency (>15 GHz) event. The rather-complete microwave and HXR spectral coverage provides a rare opportunity to uncover the origin of such event together with simultaneous EUV images. We concluded that (1) the microwave sources originates around the top section of the flaring loops with a trend of source spatial dispersion with frequency;(2) the visible movement of the microwave source from peak to peak originates from the process of new flaring loops appearing sequentially along the magnetic neutral line; 3) the optically-thin microwave spectra are hard with the indices varying from -1.2 to -0.4, and the turnover frequency always exceeds 15 GHz; 4) higher turnover/peak frequency corresponds to stronger peak intensity and harder optically-thin spectra. Using the Fokker-Planck and GX simulator codes we obtained a good fit to the observed microwave spectra and spatial distribution of the sources at all peaks, if assuming the radiating energetic electrons have the same spatial distribution and single-power-law spectra but with the number density varying in a range of 30%. We conclude that the particle acceleration in this flare happens in a compact region nearing the looptop. These results provide new constraints on the acceleration of energetic electrons and the underlying flare intermittent reconnection process.

astro-ph.SR↗

arXiv2024

Comparison of Ion-Proton Differential Speed between ICMEs and Solar Wind near 1 au

The elemental abundance of ICMEs and solar wind near 1 au is often adopted to represent the abundance in the corresponding coronal sources. However, the absolute abundance of heavy ions (relative to hydrogen) near 1 au might be different from the coronal abundance due to the ion-proton differential speed ($V_{ip}$). To illustrate the $V_{ip}$ characteristics and explore whether it influences the absolute abundance analysis for ICMEs and solar wind, we perform a statistical study on the $V_{ip}$ for He$^{2+}$, C$^{5+}$, O$^{6+}$, and Fe$^{10+}$ in both ICMEs and solar wind based on measurements of Advanced Composition Explorer. The results show that the $V_{ip}$ is negligible within ICMEs and slow solar wind ($<$ 400 km s$^{-1}$), while obvious in the intermediate (400 -- 600 km s$^{-1}$) and fast wind ($>$ 600 km s$^{-1}$). Previous studies showed that the $V_{ip}$ in ICMEs keeps negligible during propagation from 0.3 to 5 au, but in solar wind it increases with the decreasing heliocentric distance. Therefore, it might be questionable to infer the absolute abundance of coronal sources through in-situ abundance near 1 au for solar wind. Fortunately, the ion-oxygen (O$^{6+}$) differential speed ($V_{io}$) is negligible for He$^{2+}$, C$^{5+}$, and Fe$^{10+}$ within both ICMEs and solar wind, and previous studies suggested that the $V_{io}$ does not vary significantly with the heliocentric distance. This indicates that various heavy ions always flow at the same bulk speed and their relative abundance (relative to oxygen) near 1 au can represent the coronal abundance for both ICMEs and solar wind.

astro-ph.SR↗